Identification and characterization of a small-molecule inhibitor of death-associated protein kinase 1
Research output: Contribution to journal › Journal article › Research › peer-review
Theis S Wilbek, Tine Skovgaard, Fiona J Sorrell, Stefan Knapp, Jens Berthelsen, Kristian Strømgaard
A novel imidazo-pyramidazine inhibitor of DAPK1 that undergoes class-specific interactions and extends into the substrate recognition site has been identified. This inhibitor is a good starting point for the development of selective and potent inhibitors of DAPK1, with potential use against stroke and ischemia.
|Number of pages||5|
|Publication status||Published - 2 Jan 2015|