Metabolic and growth response of mink (Neovison vison) kits until 10 weeks of age when exposed to different dietary protein provision

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Metabolic and growth response of mink (Neovison vison) kits until 10 weeks of age when exposed to different dietary protein provision. / Larsson, Caroline; Fink, Rikke; Matthiesen, Connie Marianne Frank; Thomsen, Preben Dybdahl; Tauson, Anne-Helene.

In: Archives of Animal Nutrition, Vol. 66, No. 3, 2012, p. 237-255.

Research output: Contribution to journalJournal articleResearchpeer-review

Harvard

Larsson, C, Fink, R, Matthiesen, CMF, Thomsen, PD & Tauson, A-H 2012, 'Metabolic and growth response of mink (Neovison vison) kits until 10 weeks of age when exposed to different dietary protein provision', Archives of Animal Nutrition, vol. 66, no. 3, pp. 237-255. https://doi.org/10.1080/1745039X.2012.676816

APA

Larsson, C., Fink, R., Matthiesen, C. M. F., Thomsen, P. D., & Tauson, A-H. (2012). Metabolic and growth response of mink (Neovison vison) kits until 10 weeks of age when exposed to different dietary protein provision. Archives of Animal Nutrition, 66(3), 237-255. https://doi.org/10.1080/1745039X.2012.676816

Vancouver

Larsson C, Fink R, Matthiesen CMF, Thomsen PD, Tauson A-H. Metabolic and growth response of mink (Neovison vison) kits until 10 weeks of age when exposed to different dietary protein provision. Archives of Animal Nutrition. 2012;66(3):237-255. https://doi.org/10.1080/1745039X.2012.676816

Author

Larsson, Caroline ; Fink, Rikke ; Matthiesen, Connie Marianne Frank ; Thomsen, Preben Dybdahl ; Tauson, Anne-Helene. / Metabolic and growth response of mink (Neovison vison) kits until 10 weeks of age when exposed to different dietary protein provision. In: Archives of Animal Nutrition. 2012 ; Vol. 66, No. 3. pp. 237-255.

Bibtex

@article{2b59d488f4ef4c918e0d19b09c3b0908,
title = "Metabolic and growth response of mink (Neovison vison) kits until 10 weeks of age when exposed to different dietary protein provision",
abstract = "Growth performance and metabolism were investigated in mink kits (n = 210) exposed to the same dietary treatment as their dams (n = 30), i.e. high (HP; 61{\%} of metabolisable energy, ME), medium (MP; 48{\%} of ME) or low (LP; 30{\%} of ME) protein supply, from birth until 10 weeks of age. The kits were weighed weekly, and were measured by means of balance experiment and indirect calorimetry, in weeks eight and nine post-partum (p.p.). At weaning (seven weeks p.p.) and 10 weeks p.p. one kit per litter was killed and blood, liver and kidneys were collected. Plasma amino acid profiles, and hepatic abundance of mRNA for phosphoenolpyruvate carboxykinase (PEPCK), fructose 1,6-biphosphatase, pyruvate kinase and glucose-6-phosphatase (G-6-Pase) by q-PCR, were determined. There were no differences in live weights among kits the first four weeks of life when kits solely consumed milk, but male LP kits were the heaviest. After transition to solid feed MP kits weighed most at nine weeks of age (p < 0.05). At eight weeks of age, the kits fed the LP diet retained less (p < 0.05) N than HP and MP kits. Heat production did not differ among kits, although protein oxidation was higher (p < 0.001) in HP kits than in LP kits. Kits fed the LP diet had lower (p < 0.05) plasma concentrations of lysine, methionine and leucine than MP kits. Dietary treatment was not reflected in the relative abundance of any of the studied mRNAs, but kits had significantly lower abundance of all studied mRNA than their dams, ranging from 83{\%} less PEPCK abundance to 40{\%} less for G-6-Pase. The kidney mass was smallest (p < 0.01) in kits fed the LP diet, and liver masses were largest (p < 0.001) in HP kits. The results indicate that the LP diet did not meet the protein requirements for mink kits in the transition period from milk to solid feed. The capacity to regulate the rate of gluconeogenesis was even more limited in young mink kits than in adult dams. However, young mink kits can regulate protein oxidation in response to dietary protein supply, probably by adapting the size of the liver and kidneys to the level of protein supply.",
keywords = "LIFE, amino acids, blood plasma, enzyme activity, gene expression, mink, offspring, protein metabolism",
author = "Caroline Larsson and Rikke Fink and Matthiesen, {Connie Marianne Frank} and Thomsen, {Preben Dybdahl} and Anne-Helene Tauson",
year = "2012",
doi = "10.1080/1745039X.2012.676816",
language = "English",
volume = "66",
pages = "237--255",
journal = "Archives of Animal Nutrition",
issn = "1745-039X",
publisher = "Taylor & Francis",
number = "3",

}

RIS

TY - JOUR

T1 - Metabolic and growth response of mink (Neovison vison) kits until 10 weeks of age when exposed to different dietary protein provision

AU - Larsson, Caroline

AU - Fink, Rikke

AU - Matthiesen, Connie Marianne Frank

AU - Thomsen, Preben Dybdahl

AU - Tauson, Anne-Helene

PY - 2012

Y1 - 2012

N2 - Growth performance and metabolism were investigated in mink kits (n = 210) exposed to the same dietary treatment as their dams (n = 30), i.e. high (HP; 61% of metabolisable energy, ME), medium (MP; 48% of ME) or low (LP; 30% of ME) protein supply, from birth until 10 weeks of age. The kits were weighed weekly, and were measured by means of balance experiment and indirect calorimetry, in weeks eight and nine post-partum (p.p.). At weaning (seven weeks p.p.) and 10 weeks p.p. one kit per litter was killed and blood, liver and kidneys were collected. Plasma amino acid profiles, and hepatic abundance of mRNA for phosphoenolpyruvate carboxykinase (PEPCK), fructose 1,6-biphosphatase, pyruvate kinase and glucose-6-phosphatase (G-6-Pase) by q-PCR, were determined. There were no differences in live weights among kits the first four weeks of life when kits solely consumed milk, but male LP kits were the heaviest. After transition to solid feed MP kits weighed most at nine weeks of age (p < 0.05). At eight weeks of age, the kits fed the LP diet retained less (p < 0.05) N than HP and MP kits. Heat production did not differ among kits, although protein oxidation was higher (p < 0.001) in HP kits than in LP kits. Kits fed the LP diet had lower (p < 0.05) plasma concentrations of lysine, methionine and leucine than MP kits. Dietary treatment was not reflected in the relative abundance of any of the studied mRNAs, but kits had significantly lower abundance of all studied mRNA than their dams, ranging from 83% less PEPCK abundance to 40% less for G-6-Pase. The kidney mass was smallest (p < 0.01) in kits fed the LP diet, and liver masses were largest (p < 0.001) in HP kits. The results indicate that the LP diet did not meet the protein requirements for mink kits in the transition period from milk to solid feed. The capacity to regulate the rate of gluconeogenesis was even more limited in young mink kits than in adult dams. However, young mink kits can regulate protein oxidation in response to dietary protein supply, probably by adapting the size of the liver and kidneys to the level of protein supply.

AB - Growth performance and metabolism were investigated in mink kits (n = 210) exposed to the same dietary treatment as their dams (n = 30), i.e. high (HP; 61% of metabolisable energy, ME), medium (MP; 48% of ME) or low (LP; 30% of ME) protein supply, from birth until 10 weeks of age. The kits were weighed weekly, and were measured by means of balance experiment and indirect calorimetry, in weeks eight and nine post-partum (p.p.). At weaning (seven weeks p.p.) and 10 weeks p.p. one kit per litter was killed and blood, liver and kidneys were collected. Plasma amino acid profiles, and hepatic abundance of mRNA for phosphoenolpyruvate carboxykinase (PEPCK), fructose 1,6-biphosphatase, pyruvate kinase and glucose-6-phosphatase (G-6-Pase) by q-PCR, were determined. There were no differences in live weights among kits the first four weeks of life when kits solely consumed milk, but male LP kits were the heaviest. After transition to solid feed MP kits weighed most at nine weeks of age (p < 0.05). At eight weeks of age, the kits fed the LP diet retained less (p < 0.05) N than HP and MP kits. Heat production did not differ among kits, although protein oxidation was higher (p < 0.001) in HP kits than in LP kits. Kits fed the LP diet had lower (p < 0.05) plasma concentrations of lysine, methionine and leucine than MP kits. Dietary treatment was not reflected in the relative abundance of any of the studied mRNAs, but kits had significantly lower abundance of all studied mRNA than their dams, ranging from 83% less PEPCK abundance to 40% less for G-6-Pase. The kidney mass was smallest (p < 0.01) in kits fed the LP diet, and liver masses were largest (p < 0.001) in HP kits. The results indicate that the LP diet did not meet the protein requirements for mink kits in the transition period from milk to solid feed. The capacity to regulate the rate of gluconeogenesis was even more limited in young mink kits than in adult dams. However, young mink kits can regulate protein oxidation in response to dietary protein supply, probably by adapting the size of the liver and kidneys to the level of protein supply.

KW - LIFE

KW - amino acids

KW - blood plasma

KW - enzyme activity

KW - gene expression

KW - mink

KW - offspring

KW - protein metabolism

U2 - 10.1080/1745039X.2012.676816

DO - 10.1080/1745039X.2012.676816

M3 - Journal article

VL - 66

SP - 237

EP - 255

JO - Archives of Animal Nutrition

JF - Archives of Animal Nutrition

SN - 1745-039X

IS - 3

ER -

ID: 38105767