Mulig terapeutisk intervention med haemmere og fremmere af fosfolipase A 2 -subtyper

Research output: Contribution to journalJournal articleResearchpeer-review

Miriam Kolko, Chen Zhan, Jens Rovelt Andreasen, Jan Ulrik Prause, Steffen Heegaard, Miriam Kolko

Phospholipase A2 (PLA2) is a group of enzymes discovered more than a century ago in insect and snake poison. Not more than 20 years ago they were identified in vertebrates, and during the last five years, research has accelerated in relation to isolating and cloning several members of this super-family in humans. PLA2 inhibitors are in the process of being developed for pharmaceutical use. The purpose of this review is to outline the relevance and prospectives of PLA2 in a clinical perspective.

Translated title of the contributionPossible therapeutic intervention with inhibitors and promoters of phospholipase A2 subtypes
Original languageDanish
JournalUgeskrift for Laeger
Volume169
Issue number2
Pages (from-to)115-9
Number of pages5
Publication statusPublished - 8 Jan 2007

ID: 128614884