Nonselective matrix metalloproteinase but not tumor necrosis factor-a inhibition effectively preserves the early critical colon anastomotic integrity

Research output: Contribution to journalJournal articleResearchpeer-review

Magnus S. Ågren, Thomas L. Andersen, Line Andersen, Christine Bruun Schiødt, Vikas Surve, Troels T. Andreassen, Juha Risteli, Lennart E. Franzén, Jean-Marie Delaissé, Anne-Marie Heegaard, Lars Nannestad Jørgensen

Increased matrix metalloproteinase (MMP) activity has been implicated in the pathogenesis of colorectal anastomotic leakage. Tumor necrosis factor-a (TNF-a) induces MMPs and may influence anastomosis repair.
Original languageEnglish
JournalInternational Journal of Colorectal Disease
Issue number3
Pages (from-to)329-337
Number of pages9
Publication statusPublished - 2011

ID: 32908433