Novel screening assay for in vivo selection of Klebsiella pneumoniae genes promoting gastrointestinal colonisation

Research output: Contribution to journalJournal articleResearchpeer-review

Erik J. Boll, Lene N Nielsen, Karen A. Krogfelt, Carsten Struve

Klebsiella pneumoniae is an important opportunistic pathogen causing pneumonia, sepsis and urinary tract infections. Colonisation of the gastrointestinal (GI) tract is a key step in the development of infections; yet the specific factors important for K. pneumoniae to colonize and reside in the GI tract of the host are largely unknown. To identify K. pneumoniae genes promoting GI colonisation, a novel genomic-library-based approach was employed.
Original languageEnglish
JournalB M C Microbiology
Volume12
Issue number201
Number of pages8
ISSN1471-2180
DOIs
Publication statusPublished - 2012

ID: 43935300