Palladium-catalyzed asymmetric allylic alkylation of a-aryl ketones

Research output: Contribution to journalJournal article

Standard

Palladium-catalyzed asymmetric allylic alkylation of a-aryl ketones. / Trost, B.M.; Schroeder, G.M.; Kristensen, Jesper Langgaard.

In: Angewandte Chemie International Edition, Vol. 41, No. 18, 16.09.2002, p. 3492-3495.

Research output: Contribution to journalJournal article

Harvard

Trost, BM, Schroeder, GM & Kristensen, JL 2002, 'Palladium-catalyzed asymmetric allylic alkylation of a-aryl ketones', Angewandte Chemie International Edition, vol. 41, no. 18, pp. 3492-3495. https://doi.org/10.1002/1521-3773(20020916)41:18<3492::aid-anie3492>3.0.CO;2-P

APA

Trost, B. M., Schroeder, G. M., & Kristensen, J. L. (2002). Palladium-catalyzed asymmetric allylic alkylation of a-aryl ketones. Angewandte Chemie International Edition, 41(18), 3492-3495. https://doi.org/10.1002/1521-3773(20020916)41:18<3492::aid-anie3492>3.0.CO;2-P

Vancouver

Trost BM, Schroeder GM, Kristensen JL. Palladium-catalyzed asymmetric allylic alkylation of a-aryl ketones. Angewandte Chemie International Edition. 2002 Sep 16;41(18):3492-3495. https://doi.org/10.1002/1521-3773(20020916)41:18<3492::aid-anie3492>3.0.CO;2-P

Author

Trost, B.M. ; Schroeder, G.M. ; Kristensen, Jesper Langgaard. / Palladium-catalyzed asymmetric allylic alkylation of a-aryl ketones. In: Angewandte Chemie International Edition. 2002 ; Vol. 41, No. 18. pp. 3492-3495.

Bibtex

@article{ebf6e59c63cf40a38965af00a5c924da,
title = "Palladium-catalyzed asymmetric allylic alkylation of a-aryl ketones",
abstract = "Quaternary centers can be created asymmetrically in high enantiomeric excess by the proper choice of ligand and metal cation in the Pd-catalyzed asymmetric allylic alkylation of a-aryl ketones. A broad range of ketone enolates can be tolerated in the reaction, as illustrated by the synthesis of conformationally constrained {\ss}-tetralone in 96{\%} ee (see scheme, DBU = 1,8-diazabicyclo[5.4.0]undec-7-ene).",
author = "B.M. Trost and G.M. Schroeder and Kristensen, {Jesper Langgaard}",
year = "2002",
month = "9",
day = "16",
doi = "10.1002/1521-3773(20020916)41:18<3492::aid-anie3492>3.0.CO;2-P",
language = "English",
volume = "41",
pages = "3492--3495",
journal = "Angewandte Chemie International Edition",
issn = "1433-7851",
publisher = "Wiley-VCH Verlag GmbH & Co. KGaA",
number = "18",

}

RIS

TY - JOUR

T1 - Palladium-catalyzed asymmetric allylic alkylation of a-aryl ketones

AU - Trost, B.M.

AU - Schroeder, G.M.

AU - Kristensen, Jesper Langgaard

PY - 2002/9/16

Y1 - 2002/9/16

N2 - Quaternary centers can be created asymmetrically in high enantiomeric excess by the proper choice of ligand and metal cation in the Pd-catalyzed asymmetric allylic alkylation of a-aryl ketones. A broad range of ketone enolates can be tolerated in the reaction, as illustrated by the synthesis of conformationally constrained ß-tetralone in 96% ee (see scheme, DBU = 1,8-diazabicyclo[5.4.0]undec-7-ene).

AB - Quaternary centers can be created asymmetrically in high enantiomeric excess by the proper choice of ligand and metal cation in the Pd-catalyzed asymmetric allylic alkylation of a-aryl ketones. A broad range of ketone enolates can be tolerated in the reaction, as illustrated by the synthesis of conformationally constrained ß-tetralone in 96% ee (see scheme, DBU = 1,8-diazabicyclo[5.4.0]undec-7-ene).

UR - http://www.scopus.com/inward/record.url?scp=0037119732&partnerID=8YFLogxK

U2 - 10.1002/1521-3773(20020916)41:18<3492::aid-anie3492>3.0.CO;2-P

DO - 10.1002/1521-3773(20020916)41:18<3492::aid-anie3492>3.0.CO;2-P

M3 - Journal article

AN - SCOPUS:0037119732

VL - 41

SP - 3492

EP - 3495

JO - Angewandte Chemie International Edition

JF - Angewandte Chemie International Edition

SN - 1433-7851

IS - 18

ER -

ID: 45438013