Primary hepatocytes: current understanding of the regulation of metabolic enzymes and transporter proteins, and pharmaceutical practice for the use of hepatocytes in metabolism, enzyme induction, transporter, clearance, and hepatotoxicity studies

Research output: Contribution to journalJournal articleResearchpeer-review

Standard

Primary hepatocytes : current understanding of the regulation of metabolic enzymes and transporter proteins, and pharmaceutical practice for the use of hepatocytes in metabolism, enzyme induction, transporter, clearance, and hepatotoxicity studies. / Hewitt, Nicola J.; Lechón, María José Gómez; Houston, J. Brian; Hallifax, David; Brown, Hayley S.; Maurel, Patrick; Kenna, J. Gerald; Gustavsson, Lena; Lohmann, Christina; Skonberg, Christian; Guillouzo, Andre; Tuschl, Gregor; Li, Albert P.; LeCluyse, Edward; Groothuis, Geny M.M.; Hengstler, Jan G.

In: Drug Metabolism Reviews, Vol. 39, No. 1, 2007, p. 159-234.

Research output: Contribution to journalJournal articleResearchpeer-review

Harvard

Hewitt, NJ, Lechón, MJG, Houston, JB, Hallifax, D, Brown, HS, Maurel, P, Kenna, JG, Gustavsson, L, Lohmann, C, Skonberg, C, Guillouzo, A, Tuschl, G, Li, AP, LeCluyse, E, Groothuis, GMM & Hengstler, JG 2007, 'Primary hepatocytes: current understanding of the regulation of metabolic enzymes and transporter proteins, and pharmaceutical practice for the use of hepatocytes in metabolism, enzyme induction, transporter, clearance, and hepatotoxicity studies', Drug Metabolism Reviews, vol. 39, no. 1, pp. 159-234. https://doi.org/10.1080/03602530601093489

APA

Hewitt, N. J., Lechón, M. J. G., Houston, J. B., Hallifax, D., Brown, H. S., Maurel, P., ... Hengstler, J. G. (2007). Primary hepatocytes: current understanding of the regulation of metabolic enzymes and transporter proteins, and pharmaceutical practice for the use of hepatocytes in metabolism, enzyme induction, transporter, clearance, and hepatotoxicity studies. Drug Metabolism Reviews, 39(1), 159-234. https://doi.org/10.1080/03602530601093489

Vancouver

Hewitt NJ, Lechón MJG, Houston JB, Hallifax D, Brown HS, Maurel P et al. Primary hepatocytes: current understanding of the regulation of metabolic enzymes and transporter proteins, and pharmaceutical practice for the use of hepatocytes in metabolism, enzyme induction, transporter, clearance, and hepatotoxicity studies. Drug Metabolism Reviews. 2007;39(1):159-234. https://doi.org/10.1080/03602530601093489

Author

Hewitt, Nicola J. ; Lechón, María José Gómez ; Houston, J. Brian ; Hallifax, David ; Brown, Hayley S. ; Maurel, Patrick ; Kenna, J. Gerald ; Gustavsson, Lena ; Lohmann, Christina ; Skonberg, Christian ; Guillouzo, Andre ; Tuschl, Gregor ; Li, Albert P. ; LeCluyse, Edward ; Groothuis, Geny M.M. ; Hengstler, Jan G. / Primary hepatocytes : current understanding of the regulation of metabolic enzymes and transporter proteins, and pharmaceutical practice for the use of hepatocytes in metabolism, enzyme induction, transporter, clearance, and hepatotoxicity studies. In: Drug Metabolism Reviews. 2007 ; Vol. 39, No. 1. pp. 159-234.

Bibtex

@article{bc3f5e90c80a11dcbee902004c4f4f50,
title = "Primary hepatocytes: current understanding of the regulation of metabolic enzymes and transporter proteins, and pharmaceutical practice for the use of hepatocytes in metabolism, enzyme induction, transporter, clearance, and hepatotoxicity studies",
keywords = "Former Faculty of Pharmaceutical Sciences",
author = "Hewitt, {Nicola J.} and Lech{\'o}n, {Mar{\'i}a Jos{\'e} G{\'o}mez} and Houston, {J. Brian} and David Hallifax and Brown, {Hayley S.} and Patrick Maurel and Kenna, {J. Gerald} and Lena Gustavsson and Christina Lohmann and Christian Skonberg and Andre Guillouzo and Gregor Tuschl and Li, {Albert P.} and Edward LeCluyse and Groothuis, {Geny M.M.} and Hengstler, {Jan G.}",
year = "2007",
doi = "10.1080/03602530601093489",
language = "English",
volume = "39",
pages = "159--234",
journal = "Drug Metabolism Reviews",
issn = "0360-2532",
publisher = "Taylor & Francis",
number = "1",

}

RIS

TY - JOUR

T1 - Primary hepatocytes

T2 - current understanding of the regulation of metabolic enzymes and transporter proteins, and pharmaceutical practice for the use of hepatocytes in metabolism, enzyme induction, transporter, clearance, and hepatotoxicity studies

AU - Hewitt, Nicola J.

AU - Lechón, María José Gómez

AU - Houston, J. Brian

AU - Hallifax, David

AU - Brown, Hayley S.

AU - Maurel, Patrick

AU - Kenna, J. Gerald

AU - Gustavsson, Lena

AU - Lohmann, Christina

AU - Skonberg, Christian

AU - Guillouzo, Andre

AU - Tuschl, Gregor

AU - Li, Albert P.

AU - LeCluyse, Edward

AU - Groothuis, Geny M.M.

AU - Hengstler, Jan G.

PY - 2007

Y1 - 2007

KW - Former Faculty of Pharmaceutical Sciences

U2 - 10.1080/03602530601093489

DO - 10.1080/03602530601093489

M3 - Journal article

C2 - 17364884

VL - 39

SP - 159

EP - 234

JO - Drug Metabolism Reviews

JF - Drug Metabolism Reviews

SN - 0360-2532

IS - 1

ER -

ID: 2385154