Primary hepatocytes: current understanding of the regulation of metabolic enzymes and transporter proteins, and pharmaceutical practice for the use of hepatocytes in metabolism, enzyme induction, transporter, clearance, and hepatotoxicity studies

Research output: Contribution to journalJournal articleResearchpeer-review

Nicola J. Hewitt, María José Gómez Lechón, J. Brian Houston, David Hallifax, Hayley S. Brown, Patrick Maurel, J. Gerald Kenna, Lena Gustavsson, Christina Lohmann, Christian Skonberg, Andre Guillouzo, Gregor Tuschl, Albert P. Li, Edward LeCluyse, Geny M.M. Groothuis, Jan G. Hengstler

Original languageEnglish
JournalDrug Metabolism Reviews
Volume39
Issue number1
Pages (from-to)159-234
ISSN0360-2532
DOIs
Publication statusPublished - 2007

ID: 2385154