Pulmonary intravascular macrophages in the pathogenesis of bovine pulmonary lesions caused by Actinomyces pyogenes

Research output: Contribution to journalJournal articleResearchpeer-review

Páll Skúli Leifsson, A. Basse, Henrik Michael Elvang Jensen, B. Bloch, Bent Aalbæk

Rabbit antisera raised against somatic antigens from two strains of Actinomyces pyogenes reacted specifically in a peroxidase anti-peroxidase technique which was developed for the location of the bacteria in formalin-fixed tissues. The technique was applied on experimental murine and spontaneous bovine lesions caused by A. pyogenes. By electron microscopy and immunohistochemistry it was demonstrated that pulmonary intravascular macrophages play a role in the uptake of A. pyogenes from the blood, and in the production of pyaemic pulmonary lesions
Original languageEnglish
JournalJournal of Comparative Pathology
Volume112
Issue number2
Pages (from-to)197-206
Number of pages10
ISSN0021-9975
Publication statusPublished - 1995

    Research areas

  • Former LIFE faculty - pulmonary intravascular macrophages, Arcanobacterium pyogenes, pyaemia

ID: 8087368