Recent advances in the medicinal chemistry of polyamine toxins

Research output: Contribution to journalJournal articleResearchpeer-review

K Strømgaard, K Andersen, P Krogsgaard-Larsen, J W Jaroszewski

This review describes the recent developments in the field of polyamine toxins, with focus on structure activity relationship investigations, including studies of importance of the polyamine moiety for biological activity, photolabeling studies using polyamine toxins as templates, as well as use of solid phase methods for the synthesis of polyamine toxins. The review is mainly concerned with effects of polyamine toxins on nicotinic acetylcholine receptors and ionotropic glutamate receptors.
Original languageEnglish
JournalMini - Reviews in Medicinal Chemistry
Volume1
Issue number4
Pages (from-to)317-338
Number of pages22
ISSN1389-5575
Publication statusPublished - Nov 2001

    Research areas

  • Animals, Humans, Polyamines, Quantitative Structure-Activity Relationship, Spider Venoms, Toxins, Biological, Wasp Venoms

ID: 45823711