Synergy by secretory phospholipase A2 and glutamate on inducing cell death and sustained arachidonic acid metabolic changes in primary cortical neuronal cultures

Research output: Contribution to journalJournal articleResearchpeer-review

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Synergy by secretory phospholipase A2 and glutamate on inducing cell death and sustained arachidonic acid metabolic changes in primary cortical neuronal cultures. / Kolko, M; DeCoster, M A; de Turco, E B; Bazan, N G; Kolko, Miriam.

In: The Journal of Biological Chemistry, Vol. 271, No. 51, 20.12.1996, p. 32722-8.

Research output: Contribution to journalJournal articleResearchpeer-review

Harvard

Kolko, M, DeCoster, MA, de Turco, EB, Bazan, NG & Kolko, M 1996, 'Synergy by secretory phospholipase A2 and glutamate on inducing cell death and sustained arachidonic acid metabolic changes in primary cortical neuronal cultures', The Journal of Biological Chemistry, vol. 271, no. 51, pp. 32722-8.

APA

Kolko, M., DeCoster, M. A., de Turco, E. B., Bazan, N. G., & Kolko, M. (1996). Synergy by secretory phospholipase A2 and glutamate on inducing cell death and sustained arachidonic acid metabolic changes in primary cortical neuronal cultures. The Journal of Biological Chemistry, 271(51), 32722-8.

Vancouver

Kolko M, DeCoster MA, de Turco EB, Bazan NG, Kolko M. Synergy by secretory phospholipase A2 and glutamate on inducing cell death and sustained arachidonic acid metabolic changes in primary cortical neuronal cultures. The Journal of Biological Chemistry. 1996 Dec 20;271(51):32722-8.

Author

Kolko, M ; DeCoster, M A ; de Turco, E B ; Bazan, N G ; Kolko, Miriam. / Synergy by secretory phospholipase A2 and glutamate on inducing cell death and sustained arachidonic acid metabolic changes in primary cortical neuronal cultures. In: The Journal of Biological Chemistry. 1996 ; Vol. 271, No. 51. pp. 32722-8.

Bibtex

@article{230fd5ed302644cbbd8b9b6b91aacc96,
title = "Synergy by secretory phospholipase A2 and glutamate on inducing cell death and sustained arachidonic acid metabolic changes in primary cortical neuronal cultures",
abstract = "Secretory and cytosolic phospholipases A2 (sPLA2 and cPLA2) may contribute to the release of arachidonic acid and other bioactive lipids, which are modulators of synaptic function. In primary cortical neuron cultures, neurotoxic cell death and [3H]arachidonate metabolism was studied after adding glutamate and sPLA2 from bee venom. sPLA2, at concentrations eliciting low neurotoxicity (",
keywords = "Animals, Arachidonic Acid, Bee Venoms, Cell Death, Cells, Cultured, Cerebral Cortex, Dizocilpine Maleate, Drug Synergism, Glutamates, Neurons, Neurotoxins, Phospholipases A, Phospholipases A2, Phospholipids, Rats",
author = "M Kolko and DeCoster, {M A} and {de Turco}, {E B} and Bazan, {N G} and Miriam Kolko",
year = "1996",
month = "12",
day = "20",
language = "English",
volume = "271",
pages = "32722--8",
journal = "Journal of Biological Chemistry",
issn = "0021-9258",
publisher = "American Society for Biochemistry and Molecular Biology, Inc.",
number = "51",

}

RIS

TY - JOUR

T1 - Synergy by secretory phospholipase A2 and glutamate on inducing cell death and sustained arachidonic acid metabolic changes in primary cortical neuronal cultures

AU - Kolko, M

AU - DeCoster, M A

AU - de Turco, E B

AU - Bazan, N G

AU - Kolko, Miriam

PY - 1996/12/20

Y1 - 1996/12/20

N2 - Secretory and cytosolic phospholipases A2 (sPLA2 and cPLA2) may contribute to the release of arachidonic acid and other bioactive lipids, which are modulators of synaptic function. In primary cortical neuron cultures, neurotoxic cell death and [3H]arachidonate metabolism was studied after adding glutamate and sPLA2 from bee venom. sPLA2, at concentrations eliciting low neurotoxicity (

AB - Secretory and cytosolic phospholipases A2 (sPLA2 and cPLA2) may contribute to the release of arachidonic acid and other bioactive lipids, which are modulators of synaptic function. In primary cortical neuron cultures, neurotoxic cell death and [3H]arachidonate metabolism was studied after adding glutamate and sPLA2 from bee venom. sPLA2, at concentrations eliciting low neurotoxicity (

KW - Animals

KW - Arachidonic Acid

KW - Bee Venoms

KW - Cell Death

KW - Cells, Cultured

KW - Cerebral Cortex

KW - Dizocilpine Maleate

KW - Drug Synergism

KW - Glutamates

KW - Neurons

KW - Neurotoxins

KW - Phospholipases A

KW - Phospholipases A2

KW - Phospholipids

KW - Rats

M3 - Journal article

C2 - 8955105

VL - 271

SP - 32722

EP - 32728

JO - Journal of Biological Chemistry

JF - Journal of Biological Chemistry

SN - 0021-9258

IS - 51

ER -

ID: 128615130