Unprecedented migration of N-alkoxycarbonyl groups in protected pyroglutaminol

Research output: Contribution to journalJournal article

[figure: see text] Cleavage of an O-silyl ether in an N-BOC-protected pyroglutaminol using TBAF led to an unprecedented migration of the BOC group. An investigation of the mechanism, based on experimental data and quantum mechanical calculations, is presented. Similar migration was observed for N-Cbz and N-methoxycarbonyl groups.
Original languageEnglish
JournalOrganic Letters
Volume3
Issue number3
Pages (from-to)433-5
Number of pages3
ISSN1523-7060
Publication statusPublished - 2001

    Research areas

  • Formic Acid Esters, Glutamic Acid, Magnetic Resonance Spectroscopy, Molecular Structure, Pyrroles, Quantum Theory, X-Ray Diffraction

ID: 40371953