Unprecedented migration of N-alkoxycarbonyl groups in protected pyroglutaminol
Research output: Contribution to journal › Journal article › Research › peer-review
[figure: see text] Cleavage of an O-silyl ether in an N-BOC-protected pyroglutaminol using TBAF led to an unprecedented migration of the BOC group. An investigation of the mechanism, based on experimental data and quantum mechanical calculations, is presented. Similar migration was observed for N-Cbz and N-methoxycarbonyl groups.
|Number of pages||3|
|Publication status||Published - 2001|
- Formic Acid Esters, Glutamic Acid, Magnetic Resonance Spectroscopy, Molecular Structure, Pyrroles, Quantum Theory, X-Ray Diffraction