Department of Drug Design and Pharmacology > Employees
Rasmus Prætorius Clausen
Associate Professor
Medicinal Chemistry Research
30, Building: 207
2100 København Ø
ORCID: 0000-0001-9466-9431
- neuromedicinal chemistry
- epigenetic medicinal chemistry
- biostructure based SAR studies
- peptide and protein based ligands
- organic synthesis
Selected publications
- Published
Subtype-Specific Agonists for NMDA Receptor Glycine Binding Sites
Maolanon, A. R., Risgaard, R., Wang, S. Y., Snoep, Y., Papangelis, A., Yi, F., Holley, D., Barslund, A. F., Svenstrup, N., Hansen, K. B. & Clausen, R. P., 16 Aug 2017, In : ACS Chemical Neuroscience. 8, 8, p. 1681-1687 7 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Tweaking subtype-selectivity and agonist efficacy at (S)-2-amino-3-(3-hydroxy-5-methyl-isoxazol-4-yl)propionic acid (AMPA) receptors in a small series of BnTetAMPA analogues
Wang, S-Y., Larsen, Y., Navarrete, C. V., Jensen, A. A., Nielsen, B., Al-Musaed, A., Frydenvang, K., Kastrup, J. S., Pickering, D. S. & Clausen, R. P., 2016, In : Journal of Medicinal Chemistry. 59, 5, p. 2244-2254 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Substrate- and Cofactor-independent Inhibition of Histone Demethylase KDM4C
Leurs, U., Lohse, B., Rand, K. D., Ming, S., Riise, E. S., Cole, P. A., Kristensen, J. L. & Clausen, R. P., 11 Jul 2014, In : A C S Chemical Biology. 9, 9, p. 2131-2138 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Targeting histone lysine demethylases by truncating the histone 3 tail to obtain selective substrate-based inhibitors
Lohse, B., Nielsen, A. L., Kristensen, J. B. L., Helgstrand, C., Cloos, P. A. C., Olsen, L., Gajhede, M., Clausen, R. P. & Kristensen, J. L., 19 Sep 2011, In : Angewandte Chemie International Edition. 50, 39, p. 9100-9103Research output: Contribution to journal › Journal article › Research › peer-review
- Published
α4βδ GABA receptors are high-affinity targets for γ-hydroxybutyric acid (GHB)
Absalom, N., Karim, N., Eghorn, L. F., Villumsen, I. S., Bay, T., Bräuner-Osborne, H., Frølund, B., Clausen, R. P., Olsen, J. V., Knudsen, G. M., Chebib, M. & Wellendorph, P., 14 Aug 2012, In : Proceedings of the National Academy of Sciences USA (PNAS). 109, 33, p. 13404-13409 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 1302218