Louise Fletcher Nikolajsen
Jagtvej 162, 2100 København Ø
G-protein coupled receptors (GPCRs) form one of the largest human protein families and mediate the effect of 27% of current drugs. GPCR crystal structures are very valuable for understanding basic receptor structure and function, and as basis for rational drug design. Although still very challenging, technological breakthroughs have led to the determination of more than 310 GPCR crystal structures of 59 unique receptors.
During the first part of my PhD I gained knowledge with how to crystallize GPCRs at iHuman Institute, Shanghai, China, under the supervision of Prof. Raymond Stevens. During the second part I used and distributed this knowledge at University of Copenhagen under the supervision of Prof. Jette Kastrup, Prof. Michael Gajhede, and Ass. Prof. David Gloriam.
2012-2014 M.Sc. in Molecular Biomedicine
2018 Postdoc, Department of Drug Design and Pharmacology, UCPH
2015 PhD student, Department of Drug Design and Pharmacology, UCPH
2015 Research Assistant, Department of Drug Design and Pharmacology, UCPH
2015 Occupational Trainee at University of Queensland, Australia
2014 Occupational Trainee at University of Queensland, Australia
2013 Summer school, Harvard University, USA
2011 Exchange program, Australian National University, Australia
2014 Recipient of the Novo Nordic Scholarship