Researchers in Section of Pharmacotherapy – University of Copenhagen

Trine Meldgaard Lund

Trine Meldgaard Lund

Associate Professor


  1. 2019
  2. Published

    Simultaneous quantification of high-dose naloxone and naloxone-3-β-D-glucuronide in human plasma by UHPLC-MS/MS. / Kongstad, Kenneth Thermann; Papathanasiou, Theodoros; Springborg, Anders; Lund, Trine Meldgaard; Werner, Mads Utke; Stærk, Dan.

    In: Bioanalysis, Vol. 11, 2019, p. 165-173.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Accepted/In press

    High-dose naloxone, an experimental tool uncovering latent sensitisation: pharmacokinetics in humans. / Papathanasiou, Theodoros; Springborg, Anders; Kongstad, Kenneth Thermann; Stærk, Dan; Møller, Kirsten; Taylor, Bradley K.; Lund, Trine Meldgaard; Werner, Mads U.

    In: British Journal of Anaesthesia, 2019.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. 2018
  5. Published

    Feasibility of Exposure-Response Analyses for Clinical Dose-Ranging Studies of Drug Combinations. / Papathanasiou, Theodoros; Strathe, Anders; Hooker, Andrew C; Lund, Trine Meldgaard; Overgaard, Rune Viig.

    In: The AAPS Journal, Vol. 20, 64, 05.2018.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. 2017
  7. Published

    Analysis of opioid consumption in clinical trials: a simulation based analysis of power of four approaches. / Juul, Rasmus Vestergaard; Nyberg, Joakim; Kreilgaard, Mads; Christrup, Lona Louring; Simonsson, Ulrika S. H.; Lund, Trine Meldgaard.

    In: Journal of Pharmacokinetics and Pharmacodynamics, Vol. 44, No. 4, 08.2017, p. 325-333.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Quantification of the Pharmacodynamic Interaction of Morphine and Gabapentin Using a Response Surface Approach. / Papathanasiou, Theodoros; Juul, Rasmus Vestergaard; Gabel-Jensen, Charlotte; Kreilgaard, Mads; Heegaard, Anne Marie; Lund, Trine Meldgaard.

    In: AAPS Journal, Vol. 19, No. 6, 01.11.2017, p. 1804–1813.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. 2016
  10. Published

    A Model-Based Approach for Joint Analysis of Pain Intensity and Opioid Consumption in Postoperative Pain. / Juul, Rasmus V; Knøsgaard, Katrine R; Olesen, Anne E; Pedersen, Katja Venborg; Kreilgaard, Mads; Christrup, Lona L; Osther, Palle J; Drewes, Asbjørn M; Lund, Trine M.

    In: A A P S Journal, Vol. 18, No. 4, 07.2016, p. 1013-1022.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    A pharmacokinetic-pharmacodynamic model of morphine exposure and subsequent morphine consumption in postoperative pain. / Juul, Rasmus Vestergaard; Nyberg, Joakim; Lund, Trine Meldgaard; Rasmussen, Sten; Kreilgaard, Mads; Christrup, Lona Louring; Simonsson, Ulrika S H.

    In: Pharmaceutical Research, Vol. 33, No. 5, 2016, p. 1093–1103.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    A Model-Based Approach for Joint Analysis of Pain Intensity and Opioid Consumption in Postoperative Pain. / Knøsgaard, Katrine; Juul, Rasmus Vestergaard; Olesen, Anne Estrup; Pedersen, Katja Venborg; Kreilgaard, Mads; Christrup, Lona Louring; Osther, Palle Jørn Sloth; Drewes, Asbjørn M.; Lund, Trine Meldgaard.

    2016. Poster session presented at PAGE 2016: Population Approach Group Europe, Lissabon, Portugal.

    Research output: Contribution to conferencePosterResearch

  13. Published

    Co-administration of morphine and gabapentin leads to dose dependent synergistic effects in a rat model of postoperative pain. / Papathanasiou, Theodoros; Juul, Rasmus Vestergaard; Heegaard, Anne-Marie; Kreilgaard, Mads; Lund, Trine Meldgaard.

    In: European Journal of Pharmaceutical Sciences, Vol. 82, 2016, p. 97–105.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Population pharmacokinetic modelling of morphine, gabapentin and their combination in the rat. / Papathanasiou, Theodoros; Juul, Rasmus Vestergaard; Gabel-Jensen, Charlotte; Kreilgaard, Mads; Lund, Trine Meldgaard.

    In: Pharmaceutical Research, Vol. 33, No. 11, 2016, p. 2630–2643.

    Research output: Contribution to journalJournal articleResearchpeer-review

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