Department of Drug Design and Pharmacology

  1. 2022
  2. Accepted/In press

    C-locked analogs of the antimicrobial peptide BP214

    Andersen, I. K. L., Thomsen, T. T., Rashid, J., Bobak, T. R., Oddo, A., Franzyk, Henrik, Løbner-Olesen, Anders & Hansen, Paul Robert, 7 Aug 2022, (Accepted/In press) In: Antibiotics.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Sleep-controlling neurons are sensitive and vulnerable to multiple forms of α-synuclein: implications for the early appearance of sleeping disorders in α-synucleinopathies

    Dos Santos, A. B., Skaanning, L. K., Thaneshwaran, S., Mikkelsen, E., Romero-Leguizamón, C. R., Skamris, T., Kristensen, M. P., Langkilde, Annette Eva & Kohlmeier, Kristi Anne, 26 Jul 2022, In: Cellular and Molecular Life Sciences. 79, 8, p. 450

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Validation of anti-malarial leads from natural products and traditional medicine for treatment of malaria.

    Christensen, Søren Brøgger, 25 Jul 2022, In Evidence-Based validation of herbal medicine. Mukherjee, P. K. (ed.). Amsterdam: Elsever, p. 389-407 18 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  5. E-pub ahead of print

    Hypothermic oxygenated perfusion in extended criteria donor liver transplantation-A randomized clinical trial

    Ravaioli, M., Germinario, G., Dajti, G., Sessa, Maurizio, Vasuri, F., Siniscalchi, A., Morelli, M. C., Serenari, M., Del Gaudio, M., Zanfi, C., Odaldi, F., Bertuzzo, V. R., Maroni, L., Laurenzi, A. & Cescon, M., 7 Jun 2022, (E-pub ahead of print) In: American Journal of Transplantation.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Sleep-controlling neurons are sensitive and vulnerable to multiple forms of α-synuclein: implications for the early appearance of sleeping disorders in α-synucleinopathies

    Brito dos Santos, Altair, Skaanning, L. K., Thaneskwaran, S., Mikkelsen, E., Leguizamon, Cesar Ramon Romero, Skamris, T., Kristensen, M. P., Langkilde, Annette Eva & Kohlmeier, Kristi Anne, 9 May 2022, Research Square-Preprint, 46 p.

    Research output: Working paperPreprintResearch

  7. Submitted

    Cyclic N-Locked Indolicidin Analogues with Antimicrobial Activity: Effect of Ring Size and Fatty Acid Acylation

    Lone, A., Nielsen, J. E., Thulstrup, Peter Waaben, Lund, R., Hansen, Paul Robert & Jenssen, H., 1 Feb 2022, (Submitted) In: European Journal of Medicinal Chemistry.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    (S)-2-Mercaptohistidine: A First Selective Orthosteric GluK3 Antagonist

    Poulie, Christian Bernard Matthijs, Larsen, Y., Leteneur, C., Barthet, G., Bjørn-Yoshimoto, Walden, Malhaire, F., Nielsen, B., Pin, J. P., Mulle, C., Pickering, Darryl S & Bunch, Lennart, 2022, In: ACS Chemical Neuroscience. 13, 10, p. 1580–1587

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    In Vivo Neutralization of Myotoxin II, a Phospholipase A2Homologue from Bothrops asper Venom, Using Peptides Discovered via Phage Display Technology

    Laustsen, A. H., Gless, Bengt, Jenkins, T. P., Meyhoff-Madsen, M., Bjärtun, J., Munk, A. S., Oscoz, S., Fernández, J., Gutiérrez, J. M., Lomonte, B. & Lohse, B., 2022, In: ACS Omega. 7, 18, p. 15561–15569

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    popsicleR: A R Package for Pre-processing and Quality Control Analysis of Single Cell RNA-seq Data

    Grandi, F., Caroli, J., Romano, O., Marchionni, M., Forcato, M. & Bicciato, S., 2022, In: Journal of Molecular Biology. 434, 11, 11 p., 167560.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    A GPCR-based yeast biosensor for biomedical, biotechnological, and point-of-use cannabinoid determination

    Miettinen, Karel, Leelahakorn, Nattawat, Almeida Robles, A. R., Zhao, Yong, Hansen, L. R., Nikolajsen, I. E., Andersen, Jens Bo, Givskov, Michael, Stærk, Dan, Bak, Søren & Kampranis, Sotirios, 2022, In: Nature Communications. 13, 16 p., 3664.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    A Nationwide Observational Study of Chlamydia trachomatis Infections in Denmark during the COVID-19 Pandemic

    Hedley, P. L., Hoffmann, S., Lausten-Thomsen, U., Voldstedlund, M., Bjerre, K. D., Hviid, Anders Peter, Krebs, Lone, Jensen, J. S. & Christiansen, M., 2022, In: Acta Dermato-Venereologica. 102, 5 p., adv00704.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    A nationwide questionnaire study of post-acute symptoms and health problems after SARS-CoV-2 infection in Denmark

    Sørensen, Anna Irene Vedel, Spiliopoulos, L., Bager, P., Nielsen, N. M., Hansen, J. V., Koch, A., Meder, I. K., Ethelberg, Steen & Hviid, Anders Peter, 2022, In: Nature Communications. 13, 1, 8 p., 4213.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    A systematic review of blood eosinophils and continued treatment with inhaled corticosteroids in patients with COPD

    Dalin, D. A., Løkke, A., Kristiansen, P., Jensen, C., Birkefoss, K., Christensen, H. R., Godtfredsen, Nina, Hilberg, O., Rohde, J. F., Ussing, A., Vermehren, Charlotte & Händel, M. N., 2022, In: Respiratory Medicine. 198, 11 p., 106880.

    Research output: Contribution to journalReviewResearchpeer-review

  15. Published

    Adverse Effects and Safety in Glaucoma Patients: Agreement on Clinical Trial Outcomes for Reports on Eye Drops (ASGARD)—A Delphi Consensus Statement

    Thein, A. S., Hedengran, A., Azuara-Blanco, A., Arita, R., Cvenkel, B., Gazzard, G., Heegaard, Steffen, de Paiva, C. S., Petrovski, G., Prokosch-Willing, V., Utheim, T. P., Virgili, G. & Kolko, Miriam, 2022, In: American Journal of Ophthalmology. 241, p. 190-197

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    An Evaluation of the Physicochemical Properties of Preservative-Free 0.005% (w/v) Latanoprost Ophthalmic Solutions, and the Impact on In Vitro Human Conjunctival Goblet Cell Survival

    Freiberg, Josefine Clement, Hedengran, A., Heegaard, Steffen, Petrovski, G., Jacobsen, Jette, Cvenkel, B. & Kolko, Miriam, 2022, In: Journal of Clinical Medicine. 11, 11, 3137.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    An inverse association between plasma benzoxazinoid metabolites and PSA after rye intake in men with prostate cancer revealed with a new method

    Nordin, E., Steffensen, S. K., Laursen, B. B., Andersson, S., Johansson, J., Åman, P., Hallmans, G., Borre, M., Stærk, Dan, Hanhineva, K., Fomsgaard, I. S. & Landberg, R., 2022, In: Scientific Reports. 12, 14 p., 5260.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Analysis of Thromboembolic and Thrombocytopenic Events After the AZD1222, BNT162b2, and MRNA-1273 COVID-19 Vaccines in 3 Nordic Countries

    Dag Berild, J., Bergstad Larsen, V., Myrup Thiesson, E., Lehtonen, T., Grøsland, M., Helgeland, J., Wolhlfahrt, J., Vinsløv Hansen, J., Palmu, A. A. & Hviid, Anders Peter, 2022, In: JAMA network open. 5, 6, 12 p., E2217375.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Ancient biosynthesis in an oil crop: Glucosinulate profiles in Limnanthes alba and its relatives (Limnanthaceae, Brassicales)

    Agerbirk, Niels, Pattison, David, Mandáková, T., Lysak, M. A., Montaut, S. & Stærk, Dan, 2022, In: Journal of Agricultural and Food Chemistry. 70, p. 1134-1147

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Artificial neural network vs pharmacometric model for population prediction of plasma concentration in real-world data: a case study on valproic acid

    Soeorg, H., Sverrisdóttir, Eva, Andersen, Morten, Lund, Trine Meldgaard & Sessa, Maurizio, 2022, In: Clinical Pharmacology and Therapeutics. 111, 6, p. 1278-1285

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Assessment of Seasonality and Extremely Preterm Birth in Denmark

    Hviid, Anders Peter, Laksafoss, A., Hedley, P., Lausten-Thomsen, U., Hjalgrim, Henrik, Christiansen, M. & Olsen, Sjurdur F., 2022, In: JAMA Network Open. 5, 2, 13 p., e2145800.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Astrocytic abnormalities in schizophrenia

    Saleki, K., Banazadeh, M., Abadi, B., Pirmoradi, Z., Esmaili, Z., Pourahmad, R., Kohlmeier, Kristi Anne & M, S., 2022, Astrocytes in Brain Communication and Disease. Larrivee, D. (ed.). In Tech Open Access

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  23. Published

    Bidirectional protein–protein interactions control liquid–liquid phase separation of PSD-95 and its interaction partners

    Christensen, N. R., Pedersen, Christian Parsbæk, Sereikaité, Vita, Pedersen, J. N., Vistrup-Parry, Maria, Sørensen, Andreas Toft, Otzen, D., Teilum, Kaare, Madsen, Kenneth Lindegaard & Strømgaard, Kristian, 2022, In: iScience. 25, 2, 26 p., 103808.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. E-pub ahead of print

    Biodiscoveries within the Australian plant genus Eremophila based on international and interdisciplinary collaboration: results and perspectives on outstanding ethical dilemmas

    Semple, S., Stærk, Dan, Buirchell, B., Fowler, R., Gericke, Oliver, Kjaerulff, Louise, Zhao, Yong, Pedersen, H. A., Petersen, M. J., Rasmussen, Line Fentz, Bredahl, E. K., Pedersen, Gustav Blichfeldt, McNair, Laura M., Ndi, C., Hansen, Nikolaj Lervad, Heskes, A., Bayly, M., Loland, Claus Juul, Heinz, Nanna & Møller, Birger Lindberg, 2022, (E-pub ahead of print) In: Plant Journal. 15866.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Biological and small molecule strategies in migraine therapy with relation to the CGRP family of peptides

    Edvinsson, L., Edvinsson, Jacob Carl Alexander & Haanes, Kristian Agmund, 2022, In: British Journal of Pharmacology. 179, 3, p. 371-380

    Research output: Contribution to journalReviewResearchpeer-review

  26. Published

    Chemogenetic profiling reveals PP2A-independent cytotoxicity of proposed PP2A activators iHAP1 and DT-061

    Vit, Gianmatteo, Duro, Joana Maria, Rajendraprasad, G., Hertz, Emil Peter Thrane, Holland, Lya Katrine Kauffeldt, Weisser, Melanie, McEwan, B. C., Lopez-Mendez, B., Sotelo-Parrilla, P., Jeyaprakash, A. A., Montoya, Guillermo, Mailand, Niels, Maeda, K., Kettenbach, A., Barisic, Marin & Nilsson, Jakob, 2022, In: EMBO Journal. 41, 14, e110611.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Chemogenetics defines a short-chain fatty acid receptor gut-brain axis

    Barki, N., Bolognini, D., Börjesson, U., Jenkins, L., Riddell, J., Hughes, D. I., Ulven, Trond, Hudson, B. D., Ulven, Elisabeth Rexen, Dekker, N., Tobin, A. B. & Milligan, G., 2022, In: eLife. 11, 23 p., e73777.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Class I histone deacetylases (HDAC1-3) are histone lysine delactylases

    Moreno Yruela, Carlos, Zhang, D., Wei, W., Bæk, M., Liu, W., Gao, J., Dankova, Daniela, Nielsen, A. L., Bolding, Julie Eilskov, Yang, L., Jameson, S. T., Wong, J., Olsen, Christian Adam & Zhao, Y., 2022, In: Science Advances. 8, 3, eabi6696.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Co-treatment with letrozole during ovarian stimulation for IVF/ICSI: a systematic review and meta-analysis

    Bülow, N. S., Dreyer Holt, M., Skouby, Sven O., Petersen, Kathrine Birch, Englund, A. L. M., Pinborg, Anja & Macklon, N. S., 2022, In: Reproductive BioMedicine Online. 44, 4, p. 717-736

    Research output: Contribution to journalReviewResearchpeer-review

  30. Published

    Comment on Delanaye et al: Future perspectives regarding kidney function estimates and dose adjustments

    Iversen, E., Hornum, M., Lund, Trine Meldgaard & Houlind, Morten Baltzer, 2022, In: British Journal of Clinical Pharmacology. 88, 6, p. 2998-2999

    Research output: Contribution to journalLetterResearchpeer-review

  31. Published

    Common coupling map advances GPCR-G protein selectivity

    Hauser, Alexander Sebastian, Avet, C., Normand, C., Mancini, A., Inoue, A., Bouvier, M. & Gloriam, David E., 2022, In: eLife. 11, 22 p., e74107.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Community guidelines for GPCR ligand bias: IUPHAR review 32

    Kolb, P., Kenakin, T., Alexander, S. P. H., Bermudez, M., Bohn, L. M., Breinholt, C. S., Bouvier, M., Hill, S. J., Kostenis, E., Martemyanov, K. A., Neubig, R. R., Onaran, H. O., Rajagopal, S., Roth, B. L., Selent, J., Shukla, A. K., Sommer, M. E. & Gloriam, David E., 2022, In: British Journal of Pharmacology. 179, 14, p. 3651-3674

    Research output: Contribution to journalReviewResearchpeer-review

  33. Published

    Comparative efficacy and safety of preserved versus preservative-free beta-blockers in patients with glaucoma or ocular hypertension: a systematic review

    Skov, A. G., Rives, A. S., Freiberg, Josefine Clement, Virgili, G., Azuara-Blanco, A. & Kolko, Miriam, 2022, In: Acta Ophthalmologica. 100, 3, p. 253-261

    Research output: Contribution to journalReviewResearchpeer-review

  34. Published

    Conformational decoupling in acidsensing ion channels uncovers mechanism and stoichiometry of PcTx1mediated inhibition

    Heusser, Stephanie, Borg, C. B., Colding, J. M. & Pless, Stephan, 2022, In: eLife. 11, 20 p., e73384.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Data-dependent acquisition-mass spectrometry guided isolation of new benzoxazinoids from the roots of Acanthus mollis L.

    Bhattarai, B., Steffensen, S. K., Stærk, Dan, Laursen, B. B. & Fomsgaard, I. S., 2022, In: International Journal of Mass Spectrometry. 474, 10 p., 116815.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Decreased Glucose Metabolism and Glutamine Synthesis in the Retina of a Transgenic Mouse Model of Alzheimer's Disease

    Tams, A. L. M., Sanz-Morello, B., Westi, E. W., Mouhammad, Zaynab Ahmad, Andersen, Jens Velde, Freude, Kristine, Vohra, Rupali, Hannibal, Jens, Aldana, Blanca & Kolko, Miriam, 2022, In: Cellular and Molecular Neurobiology. 42, p. 291–303

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Delineation of the GPR15 receptor-mediated Gα protein signalling profile in recombinant mammalian cells

    Deng, Y., Moo, Ee Von, Almería, C. V. P., Gentry, P. R., Vedel, L., Mathiesen, Jesper M. & Bräuner-Osborne, Hans, 2022, In: Basic and Clinical Pharmacology and Toxicology. 131, 2, p. 104-113

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Derivatives of (R)-3-(5-Furanyl)carboxamido-2-aminopropanoic Acid as Potent NMDA Receptor Glycine Site Agonists with GluN2 Subunit-Specific Activity

    Zhao, F., Atxabal, U., Mariottini, S., Yi, F., Lotti, J. S., Rouzbeh, N., Liu, N., Bunch, Lennart, Hansen, K. B. & Clausen, Rasmus Prætorius, 2022, In: Journal of Medicinal Chemistry. 65, 1, p. 734-746

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Development of18F-Labeled Bispyridyl Tetrazines for In Vivo Pretargeted PET Imaging

    García Vázquez, Rocío, Jørgensen, Jesper Tranekjær, Bratteby, K. E., Shalgunov, Vladimir, Hvass, Lars, Herth, Matthias Manfred, Kjær, Andreas & Battisti, Umberto Maria, 2022, In: Pharmaceuticals. 15, 2, 28 p., 245.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Discovery and Optimization of 5-Hydroxy-Diclofenac toward a New Class of Ligands with Nanomolar Affinity for the CaMKIIα Hub Domain

    Tian, Yongsong, Shehata, Mohamed A., Gauger, Stine Juul, Ng, C. K. L., Solbak, Sara Marie Øie, Thiesen, L., Bruus-Jensen, J., Krall, J., Bundgaard, C., Gibson, K. M., Wellendorph, Petrine & Frølund, Bente, 2022, In: Journal of Medicinal Chemistry. 65, 9, p. 6656-6676

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Drug-induced optic neuropathy

    Horwitz, Anna & Horwitz, Henrik, 2022, In: Adverse Drug Reaction Bulletin. 334, 1, p. 1295-1298

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Dual action of the cannabinoid receptor 1 ligand arachidonyl-2′-chloroethylamide on calcitonin gene-related peptide release

    Christiansen, I. M., Edvinsson, Jacob Carl Alexander, Reducha, Philip Victor, Edvinsson, L. & Haanes, Kristian Agmund, 2022, In: Journal of Headache and Pain. 23, 11 p., 30.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Editorial: Amyloid-Membrane Interactions in Protein Misfolding Disorders: From Basic Mechanisms to Therapy

    Vassallo, N., Galvagnion-Büll, Céline & Chi, E. Y., 2022, In: Frontiers in Cell and Developmental Biology. 10, 870791.

    Research output: Contribution to journalEditorialResearchpeer-review

  44. Published

    Effector membrane translocation biosensors reveal G protein and βarrestin coupling profiles of 100 therapeutically relevant GPCRs

    Avet, C., Mancini, A., Breton, B., Le Gouill, C., Hauser, Alexander Sebastian, Normand, C., Kobayashi, H., Gross, F., Hogue, M., Lukasheva, V., St-Onge, S., Carrier, M., Héroux, M., Morissette, S., Fauman, E. B., Fortin, J. P., Schann, S., Leroy, X., Gloriam, David E. & Bouvier, M., 2022, In: eLife. 11, 34 p., e74101.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Electromembrane extraction of polar substances – Status and perspectives

    Eie, L. V., Pedersen-Bjergaard, Stig & Hansen, F. A., 2022, In: Journal of Pharmaceutical and Biomedical Analysis. 207, 17 p., 114407.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Elucidating Pathway and Anesthetic Mechanism of Action of Clove Oil Nanoformulations in Fish

    Kheawfu, K., Pikulkaew, S., Wellendorph, Petrine, Jørgensen, Louise von Gersdorff, Rades, Thomas, Mullertz, Anette & Okonogi, S., 2022, In: Pharmaceutics. 14, 5, 13 p., 919.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Enhanced depth imaging optical coherence tomography of the optic nerve head improves correct diagnosis in glaucoma suspects without glaucomatous optic disc morphology

    Ahmadi, H., Kolko, Miriam & Hamann, Steffen, 2022, In: BMJ Case Reports. 15, 2, e248109.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Erythropoietin attenuates locomotor and cognitive impairments in male rats subjected to physical and psychological stress

    Fathi, M., Tahamtan, M., Kohlmeier, Kristi Anne & Shabani, M., 2022, In: IBRO Neuroscience Reports. 12, p. 303-308

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Establishing a metabolic model of osteoarthritis in rats

    Mohamed, K. E., Iken, M. S., Katri, A., Karsdal, M. & Henriksen, K., 2022, In: Osteoarthritis and Cartilage. 30, Suppl. 1, p. S329-S329 1 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  50. Published

    Estimating Renal Function Following Lung Transplantation

    nsx114, nsx114, Houlind, Morten Baltzer, Iversen, E., Porrini, E., Luis-Lima, S., Oturai, P., Iversen, M., Bredahl, P., Carlsen, Jørn, Møller, Christian H., Andersen, M. J., Feldt-Rasmussen, Bo & Perch, Michael, 2022, In: Journal of Clinical Medicine. 11, 6, 13 p., 1496.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Exploration of Symptom Scale as an Outcome for Deprescribing: A Medication Review Study in Nursing Homes

    Dalin, D. A., Frandsen, S., Madsen, G. K. & Vermehren, Charlotte, 2022, In: Pharmaceuticals. 15, 5, 13 p., 505.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Expression, purification and characterization of human proton-coupled oligopeptide transporter 1 hPEPT1

    Rafiq, Maria, Ernst, H. A., Aduri, N. G., Prabhala, B. K., Tufail, S., Rahman, M., Bloch, Magnus Borup, Mirza, N., Taylor, Nicholas M I, Boesen, T., Gajhede, Michael & Mirza, Osman Asghar, 2022, In: Protein Expression and Purification. 190, 7 p., 105990.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Factors associated with ocular surface disease and severity in adults with atopic dermatitis: a nationwide survey

    Rønnstad, A., Hansen, P. M., Halling, A. S., Egeberg, A., Kolko, Miriam, Heegaard, Steffen & Thyssen, Jacob Pontoppidan, 2022, In: Journal of the European Academy of Dermatology and Venereology : JEADV. 36, 4, p. 592-601

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    Farmakogenetik kan blive supplement til fremtidens ordinationspraksis

    Clausen, E., Koch, N. E., Christrup, Lona Louring, Houlind, Morten Baltzer & Nørgaard, Lotte Stig, 2022, In: Best Practice Nordic.

    Research output: Contribution to journalJournal articleResearch

  55. Published

    Fibrous dysplasia animal models: A systematic review

    Hopkins, Chelsea, de Castro, L. F., Corsi, A., Boyce, A., Collins, M. T., Riminucci, M. & Heegaard, Anne-Marie, 2022, In: Bone. 155, 13 p., 116270.

    Research output: Contribution to journalReviewResearchpeer-review

  56. Published

    Food purchases in households with and without diabetes based on consumer purchase data

    Sørensen, K. K., Nielsen, Emilie Prang, Møller, Amalie Lykkemark, Andersen, M. P., Møller, F. T., Melbye, Mads, Kolko, Miriam, Ejlskov, L., Køber, Lars Valeur, Gislason, Gunnar Hilmar, Starkopf, L., Gerds, T. A. & Torp-Pedersen, C., 2022, In: Primary Care Diabetes. 16, 4, p. 574-580 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. Published

    Fremtidens bæredygtige medicin fra naturen: Nye teknologier hjælper med at finde nålen i høstakken

    Stærk, Dan, 2022, In: Pharma. 2022, 2, p. 20-22

    Research output: Contribution to journalContribution to newspaper - Newspaper articleCommunication

  58. Published

    GPCRs steer Gi and Gs selectivity via TM5-TM6 switches as revealed by structures of serotonin receptors

    Huang, S., Xu, P., Shen, D., Simon, I. A., Mao, C., Tan, Y., Zhang, H., Harpsøe, Kasper, Li, H., Zhang, Y., You, C., Yu, X., Jiang, Y., Zhang, Y., Gloriam, David E. & Xu, H. E., 2022, In: Molecular Cell. 82, 14, p. 2681-2695.e6 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. Published

    GRK2 selectively attenuates the neutrophil NADPH-oxidase response triggered by β-arrestin recruiting GPR84 agonists

    Fredriksson, J., Holdfeldt, A., Mårtensson, J., Björkman, L., Møller, T. C., Müllers, E., Dahlgren, C., Sundqvist, M. & Forsman, H., 2022, In: Biochimica et Biophysica Acta - Molecular Cell Research. 1869, 7, 13 p., 119262.

    Research output: Contribution to journalJournal articleResearchpeer-review

  60. Accepted/In press
  61. Published

    Genome-wide association study of febrile seizures implicates fever response and neuronal excitability genes

    Skotte, L., Fadista, J., Bybjerg-Grauholm, J., Appadurai, V., Hildebrand, M. S., Hansen, Thomas Folkmann, Banasik, Karina, Grove, J., Albiñana, C., Geller, F., Bjurström, C. F., Vilhjálmsson, B. J., Coleman, M., Damiano, J. A., Burgess, R., Scheffer, I. E., Pedersen, Ole Birger Vesterager, Erikstrup, C., Westergaard, David, Nielsen, K. R., Sørensen, E., Bruun, M. T., Liu, X., Hjalgrim, Henrik, Pers, Tune H, Mortensen, P. B., Mors, O., Nordentoft, Merete, Dreier, J. W., Børglum, A. D., Christensen, J., Hougaard, D. M., Buil, A., Hviid, Anders Peter, Melbye, Mads, Ullum, Henrik, Berkovic, S. F., Werge, Thomas & Feenstra, B., 2022, In: Brain. 145, 2, p. 555–568

    Research output: Contribution to journalJournal articleResearchpeer-review

  62. Published

    Girl Power in Glaucoma: The Role of Estrogen in Primary Open Angle Glaucoma

    Fotesko, K., Thomsen, B. S. V., Kolko, Miriam & Vohra, Rupali, 2022, In: Cellular and Molecular Neurobiology. 42, p. 41–57

    Research output: Contribution to journalReviewResearchpeer-review

  63. Published

    Glucagon-Like Peptide 1 Receptor Agonists – Potential Game Changers in the Treatment of Glaucoma?

    Mouhammad, Zaynab Ahmad, Vohra, Rupali, Horwitz, Anna, Thein, A. S., Andreasen, Jens Rovelt, Cvenkel, B., Williams, P. A., Azuara-Blanco, A. & Kolko, Miriam, 2022, In: Frontiers in Neuroscience. 16, 824054.

    Research output: Contribution to journalReviewResearchpeer-review

  64. Published

    Highly cationic cell-penetrating peptides affect the barrier integrity and facilitates mannitol permeation in a human stem cell-based blood-brain barrier model

    Frøslev, Patrick, Franzyk, Henrik, Ozgür, Burak, Larsen, Birger Brodin & Kristensen, Mie, 2022, In: European Journal of Pharmaceutical Sciences. 168, 10 p., 106054.

    Research output: Contribution to journalJournal articleResearchpeer-review

  65. Published

    Hydroxyzine Initiation Following Drug Safety Advisories on Cardiac Arrhythmias in the UK and Canada: A Longitudinal Cohort Study

    Morrow, R. L., Mintzes, B., Souverein, P. C., Hallgreen, Christine Erikstrup, Ahmed, B., Roughead, E. E., De Bruin, M. L., Kristiansen, Sarah Brøgger, Lexchin, J., Kemp-Casey, A., Sketris, I., Mangin, D., Pearson, S. A., Puil, L., Lopert, R., Bero, L., Gnjidic, D., Sarpatwari, A. & Dormuth, C. R., 2022, In: Drug Safety. 45, p. 623–638

    Research output: Contribution to journalJournal articleResearchpeer-review

  66. Accepted/In press

    IL-4 and IL-13 both contribute to the homeostasis of human conjunctival goblet cells in vitro

    Hansen, Pernille May, Tollenaere, M. A. X., Hedengran, A., Heegaard, Steffen, Amoudruz, P., Røpke, M., Thyssen, Jacob Pontoppidan, Kolko, Miriam & Norsgaard, H., 2022, (Accepted/In press) In: Allergy: European Journal of Allergy and Clinical Immunology.

    Research output: Contribution to journalLetterResearchpeer-review

  67. Published

    Identification and Optimization of Novel Small-Molecule Cas9 Inhibitors by Cell-Based High-Throughput Screening

    Lee, S., Tran, K. T., Vazquez-Uribe, R., Gotfredsen, C. H., Clausen, M. H., Mendez, B. L., Montoya, Guillermo, Bach, Anders & Sommer, M. O. A., 2022, In: Journal of Medicinal Chemistry. 65, 4, p. 3266–3305

    Research output: Contribution to journalJournal articleResearchpeer-review

  68. Published

    Identifying molecular targets in trigeminal nociception

    Edvinsson, L., Edvinsson, Jacob Carl Alexander & Haanes, Kristian Agmund, 2022, In: Nature Reviews Neurology. 18, p. 385–386

    Research output: Contribution to journalJournal articleResearchpeer-review

  69. E-pub ahead of print

    Image-derived and physiological markers to predict adequate adenosine-induced hyperemic response in Rubidium-82 myocardial perfusion imaging

    Lassen, M. L., Wissenberg, M., Byrne, C., Sheykhzade, Majid, Hurry, P. K., Schmedes, A. V., Kjær, Andreas & Hasbak, P., 2022, (E-pub ahead of print) In: Journal of Nuclear Cardiology.

    Research output: Contribution to journalJournal articleResearchpeer-review

  70. Published

    Imitation of β-lactam binding enables broad-spectrum metallo-β-lactamase inhibitors

    Brem, J., Panduwawala, T., Hansen, J. U., Hewitt, J., Liepins, E., Donets, P., Espina, L., Farley, A. J. M., Shubin, K., Campillos, G. G., Kiuru, P., Shishodia, S., Krahn, D., Leśniak, R. K., Schmidt (Adrian), J., Calvopiña, K., Turrientes, M. C., Kavanagh, M. E., Lubriks, D., Hinchliffe, P., Langley, G. W., Aboklaish, A. F., Eneroth, A., Backlund, M., Baran, A. G., Nielsen, E. I., Speake, M., Kuka, J., Robinson, J., Grinberga, S., Robinson, L., McDonough, M. A., Rydzik, A. M., Leissing, T. M., Jimenez-Castellanos, J. C., Avison, M. B., Da Silva Pinto, S., Pannifer, A. D., Martjuga, M., Widlake, E., Priede, M., Hopkins Navratilova, I., Gniadkowski, M., Belfrage, A. K., Brandt, P., Yli-Kauhaluoma, J., Bacque, E., Page, M. G. P., Björkling, F., Tyrrell, J. M., Spencer, J., Lang, P. A., Baranczewski, P., Cantón, R., McElroy, S. P., Jones, P. S., Baquero, F., Suna, E., Morrison, A., Walsh, T. R. & Schofield, C. J., 2022, In: Nature Chemistry. 14, p. 15–24

    Research output: Contribution to journalJournal articleResearchpeer-review

  71. Published

    Impact of MELD 30-allocation policy on liver transplant outcomes in Italy

    Ravaioli, M., Lai, Q., Sessa, Maurizio, Ghinolfi, D., Fallani, G., Patrono, D., Di Sandro, S., Avolio, A., Odaldi, F., Bronzoni, J., Tandoi, F., De Carlis, R., Pascale, M. M., Mennini, G., Germinario, G., Rossi, M., Agnes, S., De Carlis, L., Cescon, M., Romagnoli, R. & De Simone, P., 2022, In: Journal of Hepatology. 76, 3, p. 619-627

    Research output: Contribution to journalJournal articleResearchpeer-review

  72. Published

    In Vitro Angiogenesis Inhibition and Endothelial Cell Growth and Morphology

    Ljoki, A., Aslam, T., Friis, T., Ohm, R. G. & Houen, G., 2022, In: International Journal of Molecular Sciences. 23, 8, 4277.

    Research output: Contribution to journalJournal articleResearchpeer-review

  73. Published

    Incidence of hospital contacts with acute kidney injury after initiation of second-generation antipsychotics in older adults: a Danish population-based cohort study

    Sharon, Reeha, Lange, Theis, Aakjær, Mia, Kristiansen, Sarah Brøgger, Houlind, Morten Baltzer & Andersen, Morten, 2022, In: European Journal of Clinical Pharmacology. 78, p. 1341–1349 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  74. Published

    Inhalable Composite Microparticles Containing siRNA-Loaded Lipid-Polymer Hybrid Nanoparticles: Saccharides and Leucine Preserve Aerosol Performance and Long-Term Physical Stability

    Xu, You, Turan, E. T., Shi, Z., Franzyk, Henrik, Thakur, A. & Foged, Camilla, 2022, In: Frontiers in Drug Delivery. 2, 15 p., 945459.

    Research output: Contribution to journalJournal articleResearchpeer-review

  75. Published

    Interleukin (IL)-13 and IL-4 promote proliferation and mRNA expression of MUC2 and MUC5AC in primary human conjunctival goblet cells

    Tollenaere, M. A. X., Hansen, Pernille May, Nagstrup, S., Heegaard, Anne-Marie, Roepke, M., Schneider, S., Norsgaard, H., Thyssen, Jacob Pontoppidan & Kolko, Miriam, 2022, In: British Journal of Dermatology. 186, 4, p. E146-E146 1 p., 620.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  76. Published

    Investigation of Carboxylic Acid Isosteres and Prodrugs for Inhibition of the Human SIRT5 Lysine Deacylase Enzyme**

    Rajabi, N., Hansen, Tobias Nørby, Nielsen, A. L., Nguyen, H. T., Bæk, M., Bolding, Julie Eilskov, Bahlke, O., Petersen, S. E. G., Bartling, Christian Reinhard Otto, Strømgaard, Kristian & Olsen, Christian Adam, 2022, In: Angewandte Chemie - International Edition. 61, 22, 9 p., e202115805.

    Research output: Contribution to journalJournal articleResearchpeer-review

  77. E-pub ahead of print

    Investigation of the potential association between the use of fluoxetine and occurrence of acute pancreatitis: a Danish register-based cohort study

    Aakjær, Mia, Kristiansen, Sarah Brøgger, Pape, K., Sessa, Maurizio, Dalhoff, Kim, De Bruin, M. L. & Andersen, Morten, 2022, (E-pub ahead of print) In: International Journal of Epidemiology. 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  78. Published

    Isolation and structure elucidation of caryophyllane sesquiterpenoids from leaves of Eremophila spathulata

    Bredahl, E. K., Kjaerulff, Louise, Ndi, C., Semple, S., Buirchell, B., Møller, Birger Lindberg & Stærk, Dan, 2022, In: Phytochemistry Letters. 47, p. 156-163

    Research output: Contribution to journalJournal articleResearchpeer-review

  79. Published

    KiSSim: Predicting Off-Targets from Structural Similarities in the Kinome

    Sydow, D., Aßmann, E., Kooistra, Albert Jelke, Rippmann, F. & Volkamer, A., 2022, In: Journal of Chemical Information and Modeling. 62, 10, p. 2600–2616

    Research output: Contribution to journalJournal articleResearchpeer-review

  80. Accepted/In press

    Kinase-targeting small-molecule inhibitors and emerging bifunctional molecules

    Goebel, G. L., Qiu, X. & Wu, P., 2022, (Accepted/In press) In: Trends in Pharmacological Sciences.

    Research output: Contribution to journalReviewResearchpeer-review

  81. Published

    Lasmiditan and 5-Hydroxytryptamine in the rat trigeminal system: expression, release and interactions with 5-HT1 receptors

    Edvinsson, Jacob Carl Alexander, Maddahi, A., Christiansen, I. M., Reducha, Philip Victor, Warfvinge, K., Sheykhzade, Majid, Edvinsson, L. & Haanes, Kristian Agmund, 2022, In: The Journal of Headache and Pain. 23, 19 p., 26.

    Research output: Contribution to journalJournal articleResearchpeer-review

  82. Published

    Leucine improves the aerosol performance of dry powder inhaler formulations of siRNA-loaded nanoparticles

    Xu, Y., Harinck, L., Lokras, Abhijeet Girish, Gerde, P., Selg, E., Sjöberg, C., Franzyk, Henrik, Thakur, A. & Foged, Camilla, 2022, In: International Journal of Pharmaceutics. 621, 14 p., 121758.

    Research output: Contribution to journalJournal articleResearchpeer-review

  83. Published

    Ligand-directed bias of G protein signaling at the dopamine D2 receptor

    Moo, Ee Von, Harpsøe, Kasper, Hauser, Alexander Sebastian, Masuho, I., Bräuner-Osborne, Hans, Gloriam, David E. & Martemyanov, K. A., 2022, In: Cell Chemical Biology. 29, 2, p. 226-238

    Research output: Contribution to journalJournal articleResearchpeer-review

  84. Accepted/In press

    Long-term immune cell profiling in stroke patients with or without infections

    Sørensen, N. V., Hasseldam, Henrik, Johansen, F. F., Kristiansen, Uffe, Overgaard, K., Iversen, Helle Klingenberg & Rasmussen, Rune Skovgaard, 2022, (Accepted/In press) In: International Journal of Neuroscience.

    Research output: Contribution to journalJournal articleResearchpeer-review

  85. E-pub ahead of print

    Lower calcium levels in hair of Parkinson's disease patients are associated with presence of sleeping disturbances

    Brito dos Santos, Altair, Bezerra, M. A., Rocha, M. E., Barreto, G. E. & Kohlmeier, Kristi Anne, 2022, (E-pub ahead of print) In: Nutritional Neuroscience. 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  86. Published

    Medicines Reconciliation in the Emergency Department: Important Prescribing Discrepancies between the Shared Medication Record and Patients’ Actual Use of Medication

    Andersen, T. S., Gemmer, M. N., Sejberg, H. R. C., Jørgensen, Lillian Mørch, Kallemose, T., Andersen, Ove, Iversen, E. & Houlind, Morten Baltzer, 2022, In: Pharmaceuticals. 15, 2, 13 p., 142.

    Research output: Contribution to journalJournal articleResearchpeer-review

  87. E-pub ahead of print

    Modulation of the CB1 cannabinoid receptor has potential therapeutic utility in the 3-acetylpyridine cerebellar ataxia rat model

    Ranjbar, H., Soti, M., Janahmadi, M., Kohlmeier, Kristi Anne, Sheibani, V., Ahmadi-Zeidabadi, M. & Shabani, M., 2022, (E-pub ahead of print) In: Experimental Brain Research.

    Research output: Contribution to journalJournal articleResearchpeer-review

  88. Published

    Molecular and in vivo phenotyping of missense variants of the human glucagon receptor

    van der Velden, W. J. C., Lindquist, P., Madsen, J. S., Stassen, R. H. M. J., Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Hauser, Alexander Sebastian & Rosenkilde, M. M., 2022, In: Journal of Biological Chemistry. 298, 2, 101413.

    Research output: Contribution to journalJournal articleResearchpeer-review

  89. Published

    Molecular insights into ligand recognition and G protein coupling of the neuromodulatory orphan receptor GPR139

    Zhou, Y., Daver, H., Trapkov, B., Wu, L., Wu, M., Harpsøe, Kasper, Gentry, P. R., Liu, K., Larionova, M., Liu, J., Chen, N., Bräuner-Osborne, Hans, Gloriam, David E., Hua, T. & Liu, Z. J., 2022, In: Cell Research. 32, 2, p. 210-213

    Research output: Contribution to journalLetterResearchpeer-review

  90. Published

    Neuropathic-like Pain in Fibrous Dysplasia/McCune-Albright Syndrome

    Spencer, T. L., Watts, L., Soni, A., Pinedo-Villanueva, R., Heegaard, Anne-Marie, Boyce, A. M. & Javaid, M. K., 2022, In: The Journal of clinical endocrinology and metabolism. 107, 6, p. e2258-e2266

    Research output: Contribution to journalJournal articleResearchpeer-review

  91. Published

    Neuropeptides and the Nodes of Ranvier in Cranial Headaches

    Edvinsson, Jacob Carl Alexander, Haanes, Kristian Agmund & Edvinsson, L., 2022, In: Frontiers in Physiology. 12, 8 p., 820037.

    Research output: Contribution to journalReviewResearchpeer-review

  92. Published

    On-Resin Peptide Cyclization Using the 3-Amino-4-(Methylamino)Benzoic Acid MeDbz Linker

    Gless, Bengt & Olsen, Christian Adam, 2022, Methods in Molecular Biology. Humana Press, p. 101-115 (Methods in Molecular Biology, Vol. 2371).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  93. Published

    Optimization of Direct Aromatic 18F‐Labeling of Tetrazines

    Andersen, Ida Vang, García Vázquez, Rocío, Battisti, Umberto Maria & Herth, Matthias Manfred, 2022, In: Molecules. 27, 13, 11 p., 4022.

    Research output: Contribution to journalJournal articleResearchpeer-review

  94. Published

    P2X2 receptor subunit interfaces are missense variant hotspots, where mutations tend to increase apparent ATP affinity

    Gasparri, F., Sarkar, Debayan, Bielickaite, S., Poulsen, Mette Homann, Hauser, Alexander Sebastian & Pless, Stephan, 2022, In: British Journal of Pharmacology. 179, 14, p. 3859-3874

    Research output: Contribution to journalJournal articleResearchpeer-review

  95. Published

    Parkinson's Disease related alterations in cannabinoid transmission

    Soty, M., Ranjbar, H., Kohlmeier, Kristi Anne & Shabani, M., 2022, In: Brain Research Bulletin. 178, p. 82-96

    Research output: Contribution to journalReviewResearchpeer-review

  96. Published

    Patient characteristics and safety outcomes in new users of ticagrelor and clopidogrel: An observational cohort study in Sweden

    Linder, M. & Andersen, Morten, 2022, In: Pharmacoepidemiology and Drug Safety. 31, 2, p. 235-246

    Research output: Contribution to journalJournal articleResearchpeer-review

  97. Published

    Peptide Antibody Reactivity to Homologous Regions in Glutamate Decarboxylase Isoforms and Coxsackievirus B4 P2C

    Trier, N. H., Valdarnini, N., Fanelli, I., Rovero, P., Hansen, Paul Robert, Schafer, C., Ciplys, E., Slibinskas, R., Pociot, F., Friis, T. & Houen, G., 2022, In: International Journal of Molecular Sciences. 23, 8, 16 p., 4424.

    Research output: Contribution to journalJournal articleResearchpeer-review

  98. Published

    Performance of the Cockcroft-Gault, Modification of Diet in Renal Disease, and new Chronic Kidney Disease Epidemiology Collaboration equations without race in older acute medical patients

    Iversen, E., Bengaard, A. K., Andersen, A., Kallemose, T., Damgaard, Morten, nsx114, nsx114, Feldt-Rasmussen, Bo, Andersen, Ove & Houlind, Morten Baltzer, 2022, In: Kidney International. 101, 5, p. 1087-1088

    Research output: Contribution to journalLetterResearchpeer-review

  99. Published

    Pharmacological and epidemiological considerations while constructing treatment episodes using observational data: A simulation study

    Pazzagli, L., Andersen, Morten & Sessa, Maurizio, 2022, In: Pharmacoepidemiology and Drug Safety. 31, 1, p. 55-60

    Research output: Contribution to journalJournal articleResearchpeer-review

  100. E-pub ahead of print

    Post-marketing safety surveillance of erenumab: new insight from Eudravigilance

    Liang, D. & Sessa, Maurizio, 2022, (E-pub ahead of print) In: Expert Opinion on Drug Safety.

    Research output: Contribution to journalJournal articleResearchpeer-review

  101. Published

    Practical considerations for navigating the regulatory landscape of non-clinical studies for clinical translation of radiopharmaceuticals

    Korde, A., Mikolajczak, R., Kolenc, P., Bouziotis, P., Westin, H., Lauritzen, M., Koole, M., Herth, Matthias Manfred, Bardiès, M., Martins, A. F., Paulo, A., Lyashchenko, S. K., Todde, S., Nag, S., Lamprou, E., Abrunhosa, A., Giammarile, F. & Decristoforo, C., 2022, In: EJNMMI Radiopharmacy and Chemistry. 7, 1, 18.

    Research output: Contribution to journalReviewResearchpeer-review

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