Department of Drug Design and Pharmacology

  1. 2022
  2. Accepted/In press

    C-locked analogs of the antimicrobial peptide BP214

    Andersen, I. K. L., Thomsen, T. T., Rashid, J., Bobak, T. R., Oddo, A., Franzyk, Henrik, Løbner-Olesen, Anders & Hansen, Paul Robert, 7 Aug 2022, (Accepted/In press) In: Antibiotics.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Sleep-controlling neurons are sensitive and vulnerable to multiple forms of α-synuclein: implications for the early appearance of sleeping disorders in α-synucleinopathies

    Dos Santos, A. B., Skaanning, L. K., Thaneshwaran, S., Mikkelsen, E., Romero-Leguizamón, C. R., Skamris, T., Kristensen, M. P., Langkilde, Annette Eva & Kohlmeier, Kristi Anne, 26 Jul 2022, In: Cellular and Molecular Life Sciences. 79, 8, p. 450

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Validation of anti-malarial leads from natural products and traditional medicine for treatment of malaria.

    Christensen, Søren Brøgger, 25 Jul 2022, In Evidence-Based validation of herbal medicine. Mukherjee, P. K. (ed.). Amsterdam: Elsever, p. 389-407 18 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  5. E-pub ahead of print

    Hypothermic oxygenated perfusion in extended criteria donor liver transplantation-A randomized clinical trial

    Ravaioli, M., Germinario, G., Dajti, G., Sessa, Maurizio, Vasuri, F., Siniscalchi, A., Morelli, M. C., Serenari, M., Del Gaudio, M., Zanfi, C., Odaldi, F., Bertuzzo, V. R., Maroni, L., Laurenzi, A. & Cescon, M., 7 Jun 2022, (E-pub ahead of print) In: American Journal of Transplantation.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Sleep-controlling neurons are sensitive and vulnerable to multiple forms of α-synuclein: implications for the early appearance of sleeping disorders in α-synucleinopathies

    Brito dos Santos, Altair, Skaanning, L. K., Thaneskwaran, S., Mikkelsen, E., Leguizamon, Cesar Ramon Romero, Skamris, T., Kristensen, M. P., Langkilde, Annette Eva & Kohlmeier, Kristi Anne, 9 May 2022, Research Square-Preprint, 46 p.

    Research output: Working paperPreprintResearch

  7. Submitted

    Cyclic N-Locked Indolicidin Analogues with Antimicrobial Activity: Effect of Ring Size and Fatty Acid Acylation

    Lone, A., Nielsen, J. E., Thulstrup, Peter Waaben, Lund, R., Hansen, Paul Robert & Jenssen, H., 1 Feb 2022, (Submitted) In: European Journal of Medicinal Chemistry.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    (S)-2-Mercaptohistidine: A First Selective Orthosteric GluK3 Antagonist

    Poulie, Christian Bernard Matthijs, Larsen, Y., Leteneur, C., Barthet, G., Bjørn-Yoshimoto, Walden, Malhaire, F., Nielsen, B., Pin, J. P., Mulle, C., Pickering, Darryl S & Bunch, Lennart, 2022, In: ACS Chemical Neuroscience. 13, 10, p. 1580–1587

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    In Vivo Neutralization of Myotoxin II, a Phospholipase A2Homologue from Bothrops asper Venom, Using Peptides Discovered via Phage Display Technology

    Laustsen, A. H., Gless, Bengt, Jenkins, T. P., Meyhoff-Madsen, M., Bjärtun, J., Munk, A. S., Oscoz, S., Fernández, J., Gutiérrez, J. M., Lomonte, B. & Lohse, B., 2022, In: ACS Omega. 7, 18, p. 15561–15569

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    popsicleR: A R Package for Pre-processing and Quality Control Analysis of Single Cell RNA-seq Data

    Grandi, F., Caroli, J., Romano, O., Marchionni, M., Forcato, M. & Bicciato, S., 2022, In: Journal of Molecular Biology. 434, 11, 11 p., 167560.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    A GPCR-based yeast biosensor for biomedical, biotechnological, and point-of-use cannabinoid determination

    Miettinen, Karel, Leelahakorn, Nattawat, Almeida Robles, A. R., Zhao, Yong, Hansen, L. R., Nikolajsen, I. E., Andersen, Jens Bo, Givskov, Michael, Stærk, Dan, Bak, Søren & Kampranis, Sotirios, 2022, In: Nature Communications. 13, 16 p., 3664.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    A Nationwide Observational Study of Chlamydia trachomatis Infections in Denmark during the COVID-19 Pandemic

    Hedley, P. L., Hoffmann, S., Lausten-Thomsen, U., Voldstedlund, M., Bjerre, K. D., Hviid, Anders Peter, Krebs, Lone, Jensen, J. S. & Christiansen, M., 2022, In: Acta Dermato-Venereologica. 102, 5 p., adv00704.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    A nationwide questionnaire study of post-acute symptoms and health problems after SARS-CoV-2 infection in Denmark

    Sørensen, Anna Irene Vedel, Spiliopoulos, L., Bager, P., Nielsen, N. M., Hansen, J. V., Koch, A., Meder, I. K., Ethelberg, Steen & Hviid, Anders Peter, 2022, In: Nature Communications. 13, 1, 8 p., 4213.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    A systematic review of blood eosinophils and continued treatment with inhaled corticosteroids in patients with COPD

    Dalin, D. A., Løkke, A., Kristiansen, P., Jensen, C., Birkefoss, K., Christensen, H. R., Godtfredsen, Nina, Hilberg, O., Rohde, J. F., Ussing, A., Vermehren, Charlotte & Händel, M. N., 2022, In: Respiratory Medicine. 198, 11 p., 106880.

    Research output: Contribution to journalReviewResearchpeer-review

  15. Published

    Adverse Effects and Safety in Glaucoma Patients: Agreement on Clinical Trial Outcomes for Reports on Eye Drops (ASGARD)—A Delphi Consensus Statement

    Thein, A. S., Hedengran, A., Azuara-Blanco, A., Arita, R., Cvenkel, B., Gazzard, G., Heegaard, Steffen, de Paiva, C. S., Petrovski, G., Prokosch-Willing, V., Utheim, T. P., Virgili, G. & Kolko, Miriam, 2022, In: American Journal of Ophthalmology. 241, p. 190-197

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    An Evaluation of the Physicochemical Properties of Preservative-Free 0.005% (w/v) Latanoprost Ophthalmic Solutions, and the Impact on In Vitro Human Conjunctival Goblet Cell Survival

    Freiberg, Josefine Clement, Hedengran, A., Heegaard, Steffen, Petrovski, G., Jacobsen, Jette, Cvenkel, B. & Kolko, Miriam, 2022, In: Journal of Clinical Medicine. 11, 11, 3137.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    An inverse association between plasma benzoxazinoid metabolites and PSA after rye intake in men with prostate cancer revealed with a new method

    Nordin, E., Steffensen, S. K., Laursen, B. B., Andersson, S., Johansson, J., Åman, P., Hallmans, G., Borre, M., Stærk, Dan, Hanhineva, K., Fomsgaard, I. S. & Landberg, R., 2022, In: Scientific Reports. 12, 14 p., 5260.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Analysis of Thromboembolic and Thrombocytopenic Events After the AZD1222, BNT162b2, and MRNA-1273 COVID-19 Vaccines in 3 Nordic Countries

    Dag Berild, J., Bergstad Larsen, V., Myrup Thiesson, E., Lehtonen, T., Grøsland, M., Helgeland, J., Wolhlfahrt, J., Vinsløv Hansen, J., Palmu, A. A. & Hviid, Anders Peter, 2022, In: JAMA network open. 5, 6, 12 p., E2217375.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Ancient biosynthesis in an oil crop: Glucosinulate profiles in Limnanthes alba and its relatives (Limnanthaceae, Brassicales)

    Agerbirk, Niels, Pattison, David, Mandáková, T., Lysak, M. A., Montaut, S. & Stærk, Dan, 2022, In: Journal of Agricultural and Food Chemistry. 70, p. 1134-1147

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Artificial neural network vs pharmacometric model for population prediction of plasma concentration in real-world data: a case study on valproic acid

    Soeorg, H., Sverrisdóttir, Eva, Andersen, Morten, Lund, Trine Meldgaard & Sessa, Maurizio, 2022, In: Clinical Pharmacology and Therapeutics. 111, 6, p. 1278-1285

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Assessment of Seasonality and Extremely Preterm Birth in Denmark

    Hviid, Anders Peter, Laksafoss, A., Hedley, P., Lausten-Thomsen, U., Hjalgrim, Henrik, Christiansen, M. & Olsen, Sjurdur F., 2022, In: JAMA Network Open. 5, 2, 13 p., e2145800.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Astrocytic abnormalities in schizophrenia

    Saleki, K., Banazadeh, M., Abadi, B., Pirmoradi, Z., Esmaili, Z., Pourahmad, R., Kohlmeier, Kristi Anne & M, S., 2022, Astrocytes in Brain Communication and Disease. Larrivee, D. (ed.). In Tech Open Access

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  23. Published

    Bidirectional protein–protein interactions control liquid–liquid phase separation of PSD-95 and its interaction partners

    Christensen, N. R., Pedersen, Christian Parsbæk, Sereikaité, Vita, Pedersen, J. N., Vistrup-Parry, Maria, Sørensen, Andreas Toft, Otzen, D., Teilum, Kaare, Madsen, Kenneth Lindegaard & Strømgaard, Kristian, 2022, In: iScience. 25, 2, 26 p., 103808.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. E-pub ahead of print

    Biodiscoveries within the Australian plant genus Eremophila based on international and interdisciplinary collaboration: results and perspectives on outstanding ethical dilemmas

    Semple, S., Stærk, Dan, Buirchell, B., Fowler, R., Gericke, Oliver, Kjaerulff, Louise, Zhao, Yong, Pedersen, H. A., Petersen, M. J., Rasmussen, Line Fentz, Bredahl, E. K., Pedersen, Gustav Blichfeldt, McNair, Laura M., Ndi, C., Hansen, Nikolaj Lervad, Heskes, A., Bayly, M., Loland, Claus Juul, Heinz, Nanna & Møller, Birger Lindberg, 2022, (E-pub ahead of print) In: Plant Journal. 15866.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Biological and small molecule strategies in migraine therapy with relation to the CGRP family of peptides

    Edvinsson, L., Edvinsson, Jacob Carl Alexander & Haanes, Kristian Agmund, 2022, In: British Journal of Pharmacology. 179, 3, p. 371-380

    Research output: Contribution to journalReviewResearchpeer-review

  26. Published

    Chemogenetic profiling reveals PP2A-independent cytotoxicity of proposed PP2A activators iHAP1 and DT-061

    Vit, Gianmatteo, Duro, Joana Maria, Rajendraprasad, G., Hertz, Emil Peter Thrane, Holland, Lya Katrine Kauffeldt, Weisser, Melanie, McEwan, B. C., Lopez-Mendez, B., Sotelo-Parrilla, P., Jeyaprakash, A. A., Montoya, Guillermo, Mailand, Niels, Maeda, K., Kettenbach, A., Barisic, Marin & Nilsson, Jakob, 2022, In: EMBO Journal. 41, 14, e110611.

    Research output: Contribution to journalJournal articleResearchpeer-review

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