Department of Drug Design and Pharmacology

  1. 2022
  2. Accepted/In press

    C-locked analogs of the antimicrobial peptide BP214

    Andersen, I. K. L., Thomsen, T. T., Rashid, J., Bobak, T. R., Oddo, A., Franzyk, Henrik, Løbner-Olesen, Anders & Hansen, Paul Robert, 7 Aug 2022, (Accepted/In press) In: Antibiotics.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Sleep-controlling neurons are sensitive and vulnerable to multiple forms of α-synuclein: implications for the early appearance of sleeping disorders in α-synucleinopathies

    Dos Santos, A. B., Skaanning, L. K., Thaneshwaran, S., Mikkelsen, E., Romero-Leguizamón, C. R., Skamris, T., Kristensen, M. P., Langkilde, Annette Eva & Kohlmeier, Kristi Anne, 26 Jul 2022, In: Cellular and Molecular Life Sciences. 79, 8, p. 450

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Validation of anti-malarial leads from natural products and traditional medicine for treatment of malaria.

    Christensen, Søren Brøgger, 25 Jul 2022, In Evidence-Based validation of herbal medicine. Mukherjee, P. K. (ed.). Amsterdam: Elsever, p. 389-407 18 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  5. E-pub ahead of print

    Hypothermic oxygenated perfusion in extended criteria donor liver transplantation-A randomized clinical trial

    Ravaioli, M., Germinario, G., Dajti, G., Sessa, Maurizio, Vasuri, F., Siniscalchi, A., Morelli, M. C., Serenari, M., Del Gaudio, M., Zanfi, C., Odaldi, F., Bertuzzo, V. R., Maroni, L., Laurenzi, A. & Cescon, M., 7 Jun 2022, (E-pub ahead of print) In: American Journal of Transplantation.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Sleep-controlling neurons are sensitive and vulnerable to multiple forms of α-synuclein: implications for the early appearance of sleeping disorders in α-synucleinopathies

    Brito dos Santos, Altair, Skaanning, L. K., Thaneskwaran, S., Mikkelsen, E., Leguizamon, Cesar Ramon Romero, Skamris, T., Kristensen, M. P., Langkilde, Annette Eva & Kohlmeier, Kristi Anne, 9 May 2022, Research Square-Preprint, 46 p.

    Research output: Working paperPreprintResearch

  7. Submitted

    Cyclic N-Locked Indolicidin Analogues with Antimicrobial Activity: Effect of Ring Size and Fatty Acid Acylation

    Lone, A., Nielsen, J. E., Thulstrup, Peter Waaben, Lund, R., Hansen, Paul Robert & Jenssen, H., 1 Feb 2022, (Submitted) In: European Journal of Medicinal Chemistry.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    (S)-2-Mercaptohistidine: A First Selective Orthosteric GluK3 Antagonist

    Poulie, Christian Bernard Matthijs, Larsen, Y., Leteneur, C., Barthet, G., Bjørn-Yoshimoto, Walden, Malhaire, F., Nielsen, B., Pin, J. P., Mulle, C., Pickering, Darryl S & Bunch, Lennart, 2022, In: ACS Chemical Neuroscience. 13, 10, p. 1580–1587

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    In Vivo Neutralization of Myotoxin II, a Phospholipase A2Homologue from Bothrops asper Venom, Using Peptides Discovered via Phage Display Technology

    Laustsen, A. H., Gless, Bengt, Jenkins, T. P., Meyhoff-Madsen, M., Bjärtun, J., Munk, A. S., Oscoz, S., Fernández, J., Gutiérrez, J. M., Lomonte, B. & Lohse, B., 2022, In: ACS Omega. 7, 18, p. 15561–15569

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    popsicleR: A R Package for Pre-processing and Quality Control Analysis of Single Cell RNA-seq Data

    Grandi, F., Caroli, J., Romano, O., Marchionni, M., Forcato, M. & Bicciato, S., 2022, In: Journal of Molecular Biology. 434, 11, 11 p., 167560.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    A GPCR-based yeast biosensor for biomedical, biotechnological, and point-of-use cannabinoid determination

    Miettinen, Karel, Leelahakorn, Nattawat, Almeida Robles, A. R., Zhao, Yong, Hansen, L. R., Nikolajsen, I. E., Andersen, Jens Bo, Givskov, Michael, Stærk, Dan, Bak, Søren & Kampranis, Sotirios, 2022, In: Nature Communications. 13, 16 p., 3664.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    A Nationwide Observational Study of Chlamydia trachomatis Infections in Denmark during the COVID-19 Pandemic

    Hedley, P. L., Hoffmann, S., Lausten-Thomsen, U., Voldstedlund, M., Bjerre, K. D., Hviid, Anders Peter, Krebs, Lone, Jensen, J. S. & Christiansen, M., 2022, In: Acta Dermato-Venereologica. 102, 5 p., adv00704.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    A nationwide questionnaire study of post-acute symptoms and health problems after SARS-CoV-2 infection in Denmark

    Sørensen, Anna Irene Vedel, Spiliopoulos, L., Bager, P., Nielsen, N. M., Hansen, J. V., Koch, A., Meder, I. K., Ethelberg, Steen & Hviid, Anders Peter, 2022, In: Nature Communications. 13, 1, 8 p., 4213.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    A systematic review of blood eosinophils and continued treatment with inhaled corticosteroids in patients with COPD

    Dalin, D. A., Løkke, A., Kristiansen, P., Jensen, C., Birkefoss, K., Christensen, H. R., Godtfredsen, Nina, Hilberg, O., Rohde, J. F., Ussing, A., Vermehren, Charlotte & Händel, M. N., 2022, In: Respiratory Medicine. 198, 11 p., 106880.

    Research output: Contribution to journalReviewResearchpeer-review

  15. Published

    Adverse Effects and Safety in Glaucoma Patients: Agreement on Clinical Trial Outcomes for Reports on Eye Drops (ASGARD)—A Delphi Consensus Statement

    Thein, A. S., Hedengran, A., Azuara-Blanco, A., Arita, R., Cvenkel, B., Gazzard, G., Heegaard, Steffen, de Paiva, C. S., Petrovski, G., Prokosch-Willing, V., Utheim, T. P., Virgili, G. & Kolko, Miriam, 2022, In: American Journal of Ophthalmology. 241, p. 190-197

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    An Evaluation of the Physicochemical Properties of Preservative-Free 0.005% (w/v) Latanoprost Ophthalmic Solutions, and the Impact on In Vitro Human Conjunctival Goblet Cell Survival

    Freiberg, Josefine Clement, Hedengran, A., Heegaard, Steffen, Petrovski, G., Jacobsen, Jette, Cvenkel, B. & Kolko, Miriam, 2022, In: Journal of Clinical Medicine. 11, 11, 3137.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    An inverse association between plasma benzoxazinoid metabolites and PSA after rye intake in men with prostate cancer revealed with a new method

    Nordin, E., Steffensen, S. K., Laursen, B. B., Andersson, S., Johansson, J., Åman, P., Hallmans, G., Borre, M., Stærk, Dan, Hanhineva, K., Fomsgaard, I. S. & Landberg, R., 2022, In: Scientific Reports. 12, 14 p., 5260.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Analysis of Thromboembolic and Thrombocytopenic Events After the AZD1222, BNT162b2, and MRNA-1273 COVID-19 Vaccines in 3 Nordic Countries

    Dag Berild, J., Bergstad Larsen, V., Myrup Thiesson, E., Lehtonen, T., Grøsland, M., Helgeland, J., Wolhlfahrt, J., Vinsløv Hansen, J., Palmu, A. A. & Hviid, Anders Peter, 2022, In: JAMA network open. 5, 6, 12 p., E2217375.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Ancient biosynthesis in an oil crop: Glucosinulate profiles in Limnanthes alba and its relatives (Limnanthaceae, Brassicales)

    Agerbirk, Niels, Pattison, David, Mandáková, T., Lysak, M. A., Montaut, S. & Stærk, Dan, 2022, In: Journal of Agricultural and Food Chemistry. 70, p. 1134-1147

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Artificial neural network vs pharmacometric model for population prediction of plasma concentration in real-world data: a case study on valproic acid

    Soeorg, H., Sverrisdóttir, Eva, Andersen, Morten, Lund, Trine Meldgaard & Sessa, Maurizio, 2022, In: Clinical Pharmacology and Therapeutics. 111, 6, p. 1278-1285

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Assessment of Seasonality and Extremely Preterm Birth in Denmark

    Hviid, Anders Peter, Laksafoss, A., Hedley, P., Lausten-Thomsen, U., Hjalgrim, Henrik, Christiansen, M. & Olsen, Sjurdur F., 2022, In: JAMA Network Open. 5, 2, 13 p., e2145800.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Astrocytic abnormalities in schizophrenia

    Saleki, K., Banazadeh, M., Abadi, B., Pirmoradi, Z., Esmaili, Z., Pourahmad, R., Kohlmeier, Kristi Anne & M, S., 2022, Astrocytes in Brain Communication and Disease. Larrivee, D. (ed.). In Tech Open Access

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  23. Published

    Bidirectional protein–protein interactions control liquid–liquid phase separation of PSD-95 and its interaction partners

    Christensen, N. R., Pedersen, Christian Parsbæk, Sereikaité, Vita, Pedersen, J. N., Vistrup-Parry, Maria, Sørensen, Andreas Toft, Otzen, D., Teilum, Kaare, Madsen, Kenneth Lindegaard & Strømgaard, Kristian, 2022, In: iScience. 25, 2, 26 p., 103808.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. E-pub ahead of print

    Biodiscoveries within the Australian plant genus Eremophila based on international and interdisciplinary collaboration: results and perspectives on outstanding ethical dilemmas

    Semple, S., Stærk, Dan, Buirchell, B., Fowler, R., Gericke, Oliver, Kjaerulff, Louise, Zhao, Yong, Pedersen, H. A., Petersen, M. J., Rasmussen, Line Fentz, Bredahl, E. K., Pedersen, Gustav Blichfeldt, McNair, Laura M., Ndi, C., Hansen, Nikolaj Lervad, Heskes, A., Bayly, M., Loland, Claus Juul, Heinz, Nanna & Møller, Birger Lindberg, 2022, (E-pub ahead of print) In: Plant Journal. 15866.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Biological and small molecule strategies in migraine therapy with relation to the CGRP family of peptides

    Edvinsson, L., Edvinsson, Jacob Carl Alexander & Haanes, Kristian Agmund, 2022, In: British Journal of Pharmacology. 179, 3, p. 371-380

    Research output: Contribution to journalReviewResearchpeer-review

  26. Published

    Chemogenetic profiling reveals PP2A-independent cytotoxicity of proposed PP2A activators iHAP1 and DT-061

    Vit, Gianmatteo, Duro, Joana Maria, Rajendraprasad, G., Hertz, Emil Peter Thrane, Holland, Lya Katrine Kauffeldt, Weisser, Melanie, McEwan, B. C., Lopez-Mendez, B., Sotelo-Parrilla, P., Jeyaprakash, A. A., Montoya, Guillermo, Mailand, Niels, Maeda, K., Kettenbach, A., Barisic, Marin & Nilsson, Jakob, 2022, In: EMBO Journal. 41, 14, e110611.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Chemogenetics defines a short-chain fatty acid receptor gut-brain axis

    Barki, N., Bolognini, D., Börjesson, U., Jenkins, L., Riddell, J., Hughes, D. I., Ulven, Trond, Hudson, B. D., Ulven, Elisabeth Rexen, Dekker, N., Tobin, A. B. & Milligan, G., 2022, In: eLife. 11, 23 p., e73777.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Class I histone deacetylases (HDAC1-3) are histone lysine delactylases

    Moreno Yruela, Carlos, Zhang, D., Wei, W., Bæk, M., Liu, W., Gao, J., Dankova, Daniela, Nielsen, A. L., Bolding, Julie Eilskov, Yang, L., Jameson, S. T., Wong, J., Olsen, Christian Adam & Zhao, Y., 2022, In: Science Advances. 8, 3, eabi6696.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Co-treatment with letrozole during ovarian stimulation for IVF/ICSI: a systematic review and meta-analysis

    Bülow, N. S., Dreyer Holt, M., Skouby, Sven O., Petersen, Kathrine Birch, Englund, A. L. M., Pinborg, Anja & Macklon, N. S., 2022, In: Reproductive BioMedicine Online. 44, 4, p. 717-736

    Research output: Contribution to journalReviewResearchpeer-review

  30. Published

    Comment on Delanaye et al: Future perspectives regarding kidney function estimates and dose adjustments

    Iversen, E., Hornum, M., Lund, Trine Meldgaard & Houlind, Morten Baltzer, 2022, In: British Journal of Clinical Pharmacology. 88, 6, p. 2998-2999

    Research output: Contribution to journalLetterResearchpeer-review

  31. Published

    Common coupling map advances GPCR-G protein selectivity

    Hauser, Alexander Sebastian, Avet, C., Normand, C., Mancini, A., Inoue, A., Bouvier, M. & Gloriam, David E., 2022, In: eLife. 11, 22 p., e74107.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Community guidelines for GPCR ligand bias: IUPHAR review 32

    Kolb, P., Kenakin, T., Alexander, S. P. H., Bermudez, M., Bohn, L. M., Breinholt, C. S., Bouvier, M., Hill, S. J., Kostenis, E., Martemyanov, K. A., Neubig, R. R., Onaran, H. O., Rajagopal, S., Roth, B. L., Selent, J., Shukla, A. K., Sommer, M. E. & Gloriam, David E., 2022, In: British Journal of Pharmacology. 179, 14, p. 3651-3674

    Research output: Contribution to journalReviewResearchpeer-review

  33. Published

    Comparative efficacy and safety of preserved versus preservative-free beta-blockers in patients with glaucoma or ocular hypertension: a systematic review

    Skov, A. G., Rives, A. S., Freiberg, Josefine Clement, Virgili, G., Azuara-Blanco, A. & Kolko, Miriam, 2022, In: Acta Ophthalmologica. 100, 3, p. 253-261

    Research output: Contribution to journalReviewResearchpeer-review

  34. Published

    Conformational decoupling in acidsensing ion channels uncovers mechanism and stoichiometry of PcTx1mediated inhibition

    Heusser, Stephanie, Borg, C. B., Colding, J. M. & Pless, Stephan, 2022, In: eLife. 11, 20 p., e73384.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Data-dependent acquisition-mass spectrometry guided isolation of new benzoxazinoids from the roots of Acanthus mollis L.

    Bhattarai, B., Steffensen, S. K., Stærk, Dan, Laursen, B. B. & Fomsgaard, I. S., 2022, In: International Journal of Mass Spectrometry. 474, 10 p., 116815.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Decreased Glucose Metabolism and Glutamine Synthesis in the Retina of a Transgenic Mouse Model of Alzheimer's Disease

    Tams, A. L. M., Sanz-Morello, B., Westi, E. W., Mouhammad, Zaynab Ahmad, Andersen, Jens Velde, Freude, Kristine, Vohra, Rupali, Hannibal, Jens, Aldana, Blanca & Kolko, Miriam, 2022, In: Cellular and Molecular Neurobiology. 42, p. 291–303

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Delineation of the GPR15 receptor-mediated Gα protein signalling profile in recombinant mammalian cells

    Deng, Y., Moo, Ee Von, Almería, C. V. P., Gentry, P. R., Vedel, L., Mathiesen, Jesper M. & Bräuner-Osborne, Hans, 2022, In: Basic and Clinical Pharmacology and Toxicology. 131, 2, p. 104-113

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Derivatives of (R)-3-(5-Furanyl)carboxamido-2-aminopropanoic Acid as Potent NMDA Receptor Glycine Site Agonists with GluN2 Subunit-Specific Activity

    Zhao, F., Atxabal, U., Mariottini, S., Yi, F., Lotti, J. S., Rouzbeh, N., Liu, N., Bunch, Lennart, Hansen, K. B. & Clausen, Rasmus Prætorius, 2022, In: Journal of Medicinal Chemistry. 65, 1, p. 734-746

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Development of18F-Labeled Bispyridyl Tetrazines for In Vivo Pretargeted PET Imaging

    García Vázquez, Rocío, Jørgensen, Jesper Tranekjær, Bratteby, K. E., Shalgunov, Vladimir, Hvass, Lars, Herth, Matthias Manfred, Kjær, Andreas & Battisti, Umberto Maria, 2022, In: Pharmaceuticals. 15, 2, 28 p., 245.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Discovery and Optimization of 5-Hydroxy-Diclofenac toward a New Class of Ligands with Nanomolar Affinity for the CaMKIIα Hub Domain

    Tian, Yongsong, Shehata, Mohamed A., Gauger, Stine Juul, Ng, C. K. L., Solbak, Sara Marie Øie, Thiesen, L., Bruus-Jensen, J., Krall, J., Bundgaard, C., Gibson, K. M., Wellendorph, Petrine & Frølund, Bente, 2022, In: Journal of Medicinal Chemistry. 65, 9, p. 6656-6676

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Drug-induced optic neuropathy

    Horwitz, Anna & Horwitz, Henrik, 2022, In: Adverse Drug Reaction Bulletin. 334, 1, p. 1295-1298

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Dual action of the cannabinoid receptor 1 ligand arachidonyl-2′-chloroethylamide on calcitonin gene-related peptide release

    Christiansen, I. M., Edvinsson, Jacob Carl Alexander, Reducha, Philip Victor, Edvinsson, L. & Haanes, Kristian Agmund, 2022, In: Journal of Headache and Pain. 23, 11 p., 30.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Editorial: Amyloid-Membrane Interactions in Protein Misfolding Disorders: From Basic Mechanisms to Therapy

    Vassallo, N., Galvagnion-Büll, Céline & Chi, E. Y., 2022, In: Frontiers in Cell and Developmental Biology. 10, 870791.

    Research output: Contribution to journalEditorialResearchpeer-review

  44. Published

    Effector membrane translocation biosensors reveal G protein and βarrestin coupling profiles of 100 therapeutically relevant GPCRs

    Avet, C., Mancini, A., Breton, B., Le Gouill, C., Hauser, Alexander Sebastian, Normand, C., Kobayashi, H., Gross, F., Hogue, M., Lukasheva, V., St-Onge, S., Carrier, M., Héroux, M., Morissette, S., Fauman, E. B., Fortin, J. P., Schann, S., Leroy, X., Gloriam, David E. & Bouvier, M., 2022, In: eLife. 11, 34 p., e74101.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Electromembrane extraction of polar substances – Status and perspectives

    Eie, L. V., Pedersen-Bjergaard, Stig & Hansen, F. A., 2022, In: Journal of Pharmaceutical and Biomedical Analysis. 207, 17 p., 114407.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Elucidating Pathway and Anesthetic Mechanism of Action of Clove Oil Nanoformulations in Fish

    Kheawfu, K., Pikulkaew, S., Wellendorph, Petrine, Jørgensen, Louise von Gersdorff, Rades, Thomas, Mullertz, Anette & Okonogi, S., 2022, In: Pharmaceutics. 14, 5, 13 p., 919.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Enhanced depth imaging optical coherence tomography of the optic nerve head improves correct diagnosis in glaucoma suspects without glaucomatous optic disc morphology

    Ahmadi, H., Kolko, Miriam & Hamann, Steffen, 2022, In: BMJ Case Reports. 15, 2, e248109.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Erythropoietin attenuates locomotor and cognitive impairments in male rats subjected to physical and psychological stress

    Fathi, M., Tahamtan, M., Kohlmeier, Kristi Anne & Shabani, M., 2022, In: IBRO Neuroscience Reports. 12, p. 303-308

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Establishing a metabolic model of osteoarthritis in rats

    Mohamed, K. E., Iken, M. S., Katri, A., Karsdal, M. & Henriksen, K., 2022, In: Osteoarthritis and Cartilage. 30, Suppl. 1, p. S329-S329 1 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  50. Published

    Estimating Renal Function Following Lung Transplantation

    nsx114, nsx114, Houlind, Morten Baltzer, Iversen, E., Porrini, E., Luis-Lima, S., Oturai, P., Iversen, M., Bredahl, P., Carlsen, Jørn, Møller, Christian H., Andersen, M. J., Feldt-Rasmussen, Bo & Perch, Michael, 2022, In: Journal of Clinical Medicine. 11, 6, 13 p., 1496.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Exploration of Symptom Scale as an Outcome for Deprescribing: A Medication Review Study in Nursing Homes

    Dalin, D. A., Frandsen, S., Madsen, G. K. & Vermehren, Charlotte, 2022, In: Pharmaceuticals. 15, 5, 13 p., 505.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Expression, purification and characterization of human proton-coupled oligopeptide transporter 1 hPEPT1

    Rafiq, Maria, Ernst, H. A., Aduri, N. G., Prabhala, B. K., Tufail, S., Rahman, M., Bloch, Magnus Borup, Mirza, N., Taylor, Nicholas M I, Boesen, T., Gajhede, Michael & Mirza, Osman Asghar, 2022, In: Protein Expression and Purification. 190, 7 p., 105990.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Factors associated with ocular surface disease and severity in adults with atopic dermatitis: a nationwide survey

    Rønnstad, A., Hansen, P. M., Halling, A. S., Egeberg, A., Kolko, Miriam, Heegaard, Steffen & Thyssen, Jacob Pontoppidan, 2022, In: Journal of the European Academy of Dermatology and Venereology : JEADV. 36, 4, p. 592-601

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    Farmakogenetik kan blive supplement til fremtidens ordinationspraksis

    Clausen, E., Koch, N. E., Christrup, Lona Louring, Houlind, Morten Baltzer & Nørgaard, Lotte Stig, 2022, In: Best Practice Nordic.

    Research output: Contribution to journalJournal articleResearch

  55. Published

    Fibrous dysplasia animal models: A systematic review

    Hopkins, Chelsea, de Castro, L. F., Corsi, A., Boyce, A., Collins, M. T., Riminucci, M. & Heegaard, Anne-Marie, 2022, In: Bone. 155, 13 p., 116270.

    Research output: Contribution to journalReviewResearchpeer-review

  56. Published

    Food purchases in households with and without diabetes based on consumer purchase data

    Sørensen, K. K., Nielsen, Emilie Prang, Møller, Amalie Lykkemark, Andersen, M. P., Møller, F. T., Melbye, Mads, Kolko, Miriam, Ejlskov, L., Køber, Lars Valeur, Gislason, Gunnar Hilmar, Starkopf, L., Gerds, T. A. & Torp-Pedersen, C., 2022, In: Primary Care Diabetes. 16, 4, p. 574-580 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. Published

    Fremtidens bæredygtige medicin fra naturen: Nye teknologier hjælper med at finde nålen i høstakken

    Stærk, Dan, 2022, In: Pharma. 2022, 2, p. 20-22

    Research output: Contribution to journalContribution to newspaper - Newspaper articleCommunication

  58. Published

    GPCRs steer Gi and Gs selectivity via TM5-TM6 switches as revealed by structures of serotonin receptors

    Huang, S., Xu, P., Shen, D., Simon, I. A., Mao, C., Tan, Y., Zhang, H., Harpsøe, Kasper, Li, H., Zhang, Y., You, C., Yu, X., Jiang, Y., Zhang, Y., Gloriam, David E. & Xu, H. E., 2022, In: Molecular Cell. 82, 14, p. 2681-2695.e6 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. Published

    GRK2 selectively attenuates the neutrophil NADPH-oxidase response triggered by β-arrestin recruiting GPR84 agonists

    Fredriksson, J., Holdfeldt, A., Mårtensson, J., Björkman, L., Møller, T. C., Müllers, E., Dahlgren, C., Sundqvist, M. & Forsman, H., 2022, In: Biochimica et Biophysica Acta - Molecular Cell Research. 1869, 7, 13 p., 119262.

    Research output: Contribution to journalJournal articleResearchpeer-review

  60. Accepted/In press
  61. Published

    Genome-wide association study of febrile seizures implicates fever response and neuronal excitability genes

    Skotte, L., Fadista, J., Bybjerg-Grauholm, J., Appadurai, V., Hildebrand, M. S., Hansen, Thomas Folkmann, Banasik, Karina, Grove, J., Albiñana, C., Geller, F., Bjurström, C. F., Vilhjálmsson, B. J., Coleman, M., Damiano, J. A., Burgess, R., Scheffer, I. E., Pedersen, Ole Birger Vesterager, Erikstrup, C., Westergaard, David, Nielsen, K. R., Sørensen, E., Bruun, M. T., Liu, X., Hjalgrim, Henrik, Pers, Tune H, Mortensen, P. B., Mors, O., Nordentoft, Merete, Dreier, J. W., Børglum, A. D., Christensen, J., Hougaard, D. M., Buil, A., Hviid, Anders Peter, Melbye, Mads, Ullum, Henrik, Berkovic, S. F., Werge, Thomas & Feenstra, B., 2022, In: Brain. 145, 2, p. 555–568

    Research output: Contribution to journalJournal articleResearchpeer-review

  62. Published

    Girl Power in Glaucoma: The Role of Estrogen in Primary Open Angle Glaucoma

    Fotesko, K., Thomsen, B. S. V., Kolko, Miriam & Vohra, Rupali, 2022, In: Cellular and Molecular Neurobiology. 42, p. 41–57

    Research output: Contribution to journalReviewResearchpeer-review

  63. Published

    Glucagon-Like Peptide 1 Receptor Agonists – Potential Game Changers in the Treatment of Glaucoma?

    Mouhammad, Zaynab Ahmad, Vohra, Rupali, Horwitz, Anna, Thein, A. S., Andreasen, Jens Rovelt, Cvenkel, B., Williams, P. A., Azuara-Blanco, A. & Kolko, Miriam, 2022, In: Frontiers in Neuroscience. 16, 824054.

    Research output: Contribution to journalReviewResearchpeer-review

  64. Published

    Highly cationic cell-penetrating peptides affect the barrier integrity and facilitates mannitol permeation in a human stem cell-based blood-brain barrier model

    Frøslev, Patrick, Franzyk, Henrik, Ozgür, Burak, Larsen, Birger Brodin & Kristensen, Mie, 2022, In: European Journal of Pharmaceutical Sciences. 168, 10 p., 106054.

    Research output: Contribution to journalJournal articleResearchpeer-review

  65. Published

    Hydroxyzine Initiation Following Drug Safety Advisories on Cardiac Arrhythmias in the UK and Canada: A Longitudinal Cohort Study

    Morrow, R. L., Mintzes, B., Souverein, P. C., Hallgreen, Christine Erikstrup, Ahmed, B., Roughead, E. E., De Bruin, M. L., Kristiansen, Sarah Brøgger, Lexchin, J., Kemp-Casey, A., Sketris, I., Mangin, D., Pearson, S. A., Puil, L., Lopert, R., Bero, L., Gnjidic, D., Sarpatwari, A. & Dormuth, C. R., 2022, In: Drug Safety. 45, p. 623–638

    Research output: Contribution to journalJournal articleResearchpeer-review

  66. Accepted/In press

    IL-4 and IL-13 both contribute to the homeostasis of human conjunctival goblet cells in vitro

    Hansen, Pernille May, Tollenaere, M. A. X., Hedengran, A., Heegaard, Steffen, Amoudruz, P., Røpke, M., Thyssen, Jacob Pontoppidan, Kolko, Miriam & Norsgaard, H., 2022, (Accepted/In press) In: Allergy: European Journal of Allergy and Clinical Immunology.

    Research output: Contribution to journalLetterResearchpeer-review

  67. Published

    Identification and Optimization of Novel Small-Molecule Cas9 Inhibitors by Cell-Based High-Throughput Screening

    Lee, S., Tran, K. T., Vazquez-Uribe, R., Gotfredsen, C. H., Clausen, M. H., Mendez, B. L., Montoya, Guillermo, Bach, Anders & Sommer, M. O. A., 2022, In: Journal of Medicinal Chemistry. 65, 4, p. 3266–3305

    Research output: Contribution to journalJournal articleResearchpeer-review

  68. Published

    Identifying molecular targets in trigeminal nociception

    Edvinsson, L., Edvinsson, Jacob Carl Alexander & Haanes, Kristian Agmund, 2022, In: Nature Reviews Neurology. 18, p. 385–386

    Research output: Contribution to journalJournal articleResearchpeer-review

  69. E-pub ahead of print

    Image-derived and physiological markers to predict adequate adenosine-induced hyperemic response in Rubidium-82 myocardial perfusion imaging

    Lassen, M. L., Wissenberg, M., Byrne, C., Sheykhzade, Majid, Hurry, P. K., Schmedes, A. V., Kjær, Andreas & Hasbak, P., 2022, (E-pub ahead of print) In: Journal of Nuclear Cardiology.

    Research output: Contribution to journalJournal articleResearchpeer-review

  70. Published

    Imitation of β-lactam binding enables broad-spectrum metallo-β-lactamase inhibitors

    Brem, J., Panduwawala, T., Hansen, J. U., Hewitt, J., Liepins, E., Donets, P., Espina, L., Farley, A. J. M., Shubin, K., Campillos, G. G., Kiuru, P., Shishodia, S., Krahn, D., Leśniak, R. K., Schmidt (Adrian), J., Calvopiña, K., Turrientes, M. C., Kavanagh, M. E., Lubriks, D., Hinchliffe, P., Langley, G. W., Aboklaish, A. F., Eneroth, A., Backlund, M., Baran, A. G., Nielsen, E. I., Speake, M., Kuka, J., Robinson, J., Grinberga, S., Robinson, L., McDonough, M. A., Rydzik, A. M., Leissing, T. M., Jimenez-Castellanos, J. C., Avison, M. B., Da Silva Pinto, S., Pannifer, A. D., Martjuga, M., Widlake, E., Priede, M., Hopkins Navratilova, I., Gniadkowski, M., Belfrage, A. K., Brandt, P., Yli-Kauhaluoma, J., Bacque, E., Page, M. G. P., Björkling, F., Tyrrell, J. M., Spencer, J., Lang, P. A., Baranczewski, P., Cantón, R., McElroy, S. P., Jones, P. S., Baquero, F., Suna, E., Morrison, A., Walsh, T. R. & Schofield, C. J., 2022, In: Nature Chemistry. 14, p. 15–24

    Research output: Contribution to journalJournal articleResearchpeer-review

  71. Published

    Impact of MELD 30-allocation policy on liver transplant outcomes in Italy

    Ravaioli, M., Lai, Q., Sessa, Maurizio, Ghinolfi, D., Fallani, G., Patrono, D., Di Sandro, S., Avolio, A., Odaldi, F., Bronzoni, J., Tandoi, F., De Carlis, R., Pascale, M. M., Mennini, G., Germinario, G., Rossi, M., Agnes, S., De Carlis, L., Cescon, M., Romagnoli, R. & De Simone, P., 2022, In: Journal of Hepatology. 76, 3, p. 619-627

    Research output: Contribution to journalJournal articleResearchpeer-review

  72. Published

    In Vitro Angiogenesis Inhibition and Endothelial Cell Growth and Morphology

    Ljoki, A., Aslam, T., Friis, T., Ohm, R. G. & Houen, G., 2022, In: International Journal of Molecular Sciences. 23, 8, 4277.

    Research output: Contribution to journalJournal articleResearchpeer-review

  73. Published

    Incidence of hospital contacts with acute kidney injury after initiation of second-generation antipsychotics in older adults: a Danish population-based cohort study

    Sharon, Reeha, Lange, Theis, Aakjær, Mia, Kristiansen, Sarah Brøgger, Houlind, Morten Baltzer & Andersen, Morten, 2022, In: European Journal of Clinical Pharmacology. 78, p. 1341–1349 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  74. Published

    Inhalable Composite Microparticles Containing siRNA-Loaded Lipid-Polymer Hybrid Nanoparticles: Saccharides and Leucine Preserve Aerosol Performance and Long-Term Physical Stability

    Xu, You, Turan, E. T., Shi, Z., Franzyk, Henrik, Thakur, A. & Foged, Camilla, 2022, In: Frontiers in Drug Delivery. 2, 15 p., 945459.

    Research output: Contribution to journalJournal articleResearchpeer-review

  75. Published

    Interleukin (IL)-13 and IL-4 promote proliferation and mRNA expression of MUC2 and MUC5AC in primary human conjunctival goblet cells

    Tollenaere, M. A. X., Hansen, Pernille May, Nagstrup, S., Heegaard, Anne-Marie, Roepke, M., Schneider, S., Norsgaard, H., Thyssen, Jacob Pontoppidan & Kolko, Miriam, 2022, In: British Journal of Dermatology. 186, 4, p. E146-E146 1 p., 620.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  76. Published

    Investigation of Carboxylic Acid Isosteres and Prodrugs for Inhibition of the Human SIRT5 Lysine Deacylase Enzyme**

    Rajabi, N., Hansen, Tobias Nørby, Nielsen, A. L., Nguyen, H. T., Bæk, M., Bolding, Julie Eilskov, Bahlke, O., Petersen, S. E. G., Bartling, Christian Reinhard Otto, Strømgaard, Kristian & Olsen, Christian Adam, 2022, In: Angewandte Chemie - International Edition. 61, 22, 9 p., e202115805.

    Research output: Contribution to journalJournal articleResearchpeer-review

  77. E-pub ahead of print

    Investigation of the potential association between the use of fluoxetine and occurrence of acute pancreatitis: a Danish register-based cohort study

    Aakjær, Mia, Kristiansen, Sarah Brøgger, Pape, K., Sessa, Maurizio, Dalhoff, Kim, De Bruin, M. L. & Andersen, Morten, 2022, (E-pub ahead of print) In: International Journal of Epidemiology. 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  78. Published

    Isolation and structure elucidation of caryophyllane sesquiterpenoids from leaves of Eremophila spathulata

    Bredahl, E. K., Kjaerulff, Louise, Ndi, C., Semple, S., Buirchell, B., Møller, Birger Lindberg & Stærk, Dan, 2022, In: Phytochemistry Letters. 47, p. 156-163

    Research output: Contribution to journalJournal articleResearchpeer-review

  79. Published

    KiSSim: Predicting Off-Targets from Structural Similarities in the Kinome

    Sydow, D., Aßmann, E., Kooistra, Albert Jelke, Rippmann, F. & Volkamer, A., 2022, In: Journal of Chemical Information and Modeling. 62, 10, p. 2600–2616

    Research output: Contribution to journalJournal articleResearchpeer-review

  80. Accepted/In press

    Kinase-targeting small-molecule inhibitors and emerging bifunctional molecules

    Goebel, G. L., Qiu, X. & Wu, P., 2022, (Accepted/In press) In: Trends in Pharmacological Sciences.

    Research output: Contribution to journalReviewResearchpeer-review

  81. Published

    Lasmiditan and 5-Hydroxytryptamine in the rat trigeminal system: expression, release and interactions with 5-HT1 receptors

    Edvinsson, Jacob Carl Alexander, Maddahi, A., Christiansen, I. M., Reducha, Philip Victor, Warfvinge, K., Sheykhzade, Majid, Edvinsson, L. & Haanes, Kristian Agmund, 2022, In: The Journal of Headache and Pain. 23, 19 p., 26.

    Research output: Contribution to journalJournal articleResearchpeer-review

  82. Published

    Leucine improves the aerosol performance of dry powder inhaler formulations of siRNA-loaded nanoparticles

    Xu, Y., Harinck, L., Lokras, Abhijeet Girish, Gerde, P., Selg, E., Sjöberg, C., Franzyk, Henrik, Thakur, A. & Foged, Camilla, 2022, In: International Journal of Pharmaceutics. 621, 14 p., 121758.

    Research output: Contribution to journalJournal articleResearchpeer-review

  83. Published

    Ligand-directed bias of G protein signaling at the dopamine D2 receptor

    Moo, Ee Von, Harpsøe, Kasper, Hauser, Alexander Sebastian, Masuho, I., Bräuner-Osborne, Hans, Gloriam, David E. & Martemyanov, K. A., 2022, In: Cell Chemical Biology. 29, 2, p. 226-238

    Research output: Contribution to journalJournal articleResearchpeer-review

  84. Accepted/In press

    Long-term immune cell profiling in stroke patients with or without infections

    Sørensen, N. V., Hasseldam, Henrik, Johansen, F. F., Kristiansen, Uffe, Overgaard, K., Iversen, Helle Klingenberg & Rasmussen, Rune Skovgaard, 2022, (Accepted/In press) In: International Journal of Neuroscience.

    Research output: Contribution to journalJournal articleResearchpeer-review

  85. E-pub ahead of print

    Lower calcium levels in hair of Parkinson's disease patients are associated with presence of sleeping disturbances

    Brito dos Santos, Altair, Bezerra, M. A., Rocha, M. E., Barreto, G. E. & Kohlmeier, Kristi Anne, 2022, (E-pub ahead of print) In: Nutritional Neuroscience. 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  86. Published

    Medicines Reconciliation in the Emergency Department: Important Prescribing Discrepancies between the Shared Medication Record and Patients’ Actual Use of Medication

    Andersen, T. S., Gemmer, M. N., Sejberg, H. R. C., Jørgensen, Lillian Mørch, Kallemose, T., Andersen, Ove, Iversen, E. & Houlind, Morten Baltzer, 2022, In: Pharmaceuticals. 15, 2, 13 p., 142.

    Research output: Contribution to journalJournal articleResearchpeer-review

  87. E-pub ahead of print

    Modulation of the CB1 cannabinoid receptor has potential therapeutic utility in the 3-acetylpyridine cerebellar ataxia rat model

    Ranjbar, H., Soti, M., Janahmadi, M., Kohlmeier, Kristi Anne, Sheibani, V., Ahmadi-Zeidabadi, M. & Shabani, M., 2022, (E-pub ahead of print) In: Experimental Brain Research.

    Research output: Contribution to journalJournal articleResearchpeer-review

  88. Published

    Molecular and in vivo phenotyping of missense variants of the human glucagon receptor

    van der Velden, W. J. C., Lindquist, P., Madsen, J. S., Stassen, R. H. M. J., Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Hauser, Alexander Sebastian & Rosenkilde, M. M., 2022, In: Journal of Biological Chemistry. 298, 2, 101413.

    Research output: Contribution to journalJournal articleResearchpeer-review

  89. Published

    Molecular insights into ligand recognition and G protein coupling of the neuromodulatory orphan receptor GPR139

    Zhou, Y., Daver, H., Trapkov, B., Wu, L., Wu, M., Harpsøe, Kasper, Gentry, P. R., Liu, K., Larionova, M., Liu, J., Chen, N., Bräuner-Osborne, Hans, Gloriam, David E., Hua, T. & Liu, Z. J., 2022, In: Cell Research. 32, 2, p. 210-213

    Research output: Contribution to journalLetterResearchpeer-review

  90. Published

    Neuropathic-like Pain in Fibrous Dysplasia/McCune-Albright Syndrome

    Spencer, T. L., Watts, L., Soni, A., Pinedo-Villanueva, R., Heegaard, Anne-Marie, Boyce, A. M. & Javaid, M. K., 2022, In: The Journal of clinical endocrinology and metabolism. 107, 6, p. e2258-e2266

    Research output: Contribution to journalJournal articleResearchpeer-review

  91. Published

    Neuropeptides and the Nodes of Ranvier in Cranial Headaches

    Edvinsson, Jacob Carl Alexander, Haanes, Kristian Agmund & Edvinsson, L., 2022, In: Frontiers in Physiology. 12, 8 p., 820037.

    Research output: Contribution to journalReviewResearchpeer-review

  92. Published

    On-Resin Peptide Cyclization Using the 3-Amino-4-(Methylamino)Benzoic Acid MeDbz Linker

    Gless, Bengt & Olsen, Christian Adam, 2022, Methods in Molecular Biology. Humana Press, p. 101-115 (Methods in Molecular Biology, Vol. 2371).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  93. Published

    Optimization of Direct Aromatic 18F‐Labeling of Tetrazines

    Andersen, Ida Vang, García Vázquez, Rocío, Battisti, Umberto Maria & Herth, Matthias Manfred, 2022, In: Molecules. 27, 13, 11 p., 4022.

    Research output: Contribution to journalJournal articleResearchpeer-review

  94. Published

    P2X2 receptor subunit interfaces are missense variant hotspots, where mutations tend to increase apparent ATP affinity

    Gasparri, F., Sarkar, Debayan, Bielickaite, S., Poulsen, Mette Homann, Hauser, Alexander Sebastian & Pless, Stephan, 2022, In: British Journal of Pharmacology. 179, 14, p. 3859-3874

    Research output: Contribution to journalJournal articleResearchpeer-review

  95. Published

    Parkinson's Disease related alterations in cannabinoid transmission

    Soty, M., Ranjbar, H., Kohlmeier, Kristi Anne & Shabani, M., 2022, In: Brain Research Bulletin. 178, p. 82-96

    Research output: Contribution to journalReviewResearchpeer-review

  96. Published

    Patient characteristics and safety outcomes in new users of ticagrelor and clopidogrel: An observational cohort study in Sweden

    Linder, M. & Andersen, Morten, 2022, In: Pharmacoepidemiology and Drug Safety. 31, 2, p. 235-246

    Research output: Contribution to journalJournal articleResearchpeer-review

  97. Published

    Peptide Antibody Reactivity to Homologous Regions in Glutamate Decarboxylase Isoforms and Coxsackievirus B4 P2C

    Trier, N. H., Valdarnini, N., Fanelli, I., Rovero, P., Hansen, Paul Robert, Schafer, C., Ciplys, E., Slibinskas, R., Pociot, F., Friis, T. & Houen, G., 2022, In: International Journal of Molecular Sciences. 23, 8, 16 p., 4424.

    Research output: Contribution to journalJournal articleResearchpeer-review

  98. Published

    Performance of the Cockcroft-Gault, Modification of Diet in Renal Disease, and new Chronic Kidney Disease Epidemiology Collaboration equations without race in older acute medical patients

    Iversen, E., Bengaard, A. K., Andersen, A., Kallemose, T., Damgaard, Morten, nsx114, nsx114, Feldt-Rasmussen, Bo, Andersen, Ove & Houlind, Morten Baltzer, 2022, In: Kidney International. 101, 5, p. 1087-1088

    Research output: Contribution to journalLetterResearchpeer-review

  99. Published

    Pharmacological and epidemiological considerations while constructing treatment episodes using observational data: A simulation study

    Pazzagli, L., Andersen, Morten & Sessa, Maurizio, 2022, In: Pharmacoepidemiology and Drug Safety. 31, 1, p. 55-60

    Research output: Contribution to journalJournal articleResearchpeer-review

  100. E-pub ahead of print

    Post-marketing safety surveillance of erenumab: new insight from Eudravigilance

    Liang, D. & Sessa, Maurizio, 2022, (E-pub ahead of print) In: Expert Opinion on Drug Safety.

    Research output: Contribution to journalJournal articleResearchpeer-review

  101. Published

    Practical considerations for navigating the regulatory landscape of non-clinical studies for clinical translation of radiopharmaceuticals

    Korde, A., Mikolajczak, R., Kolenc, P., Bouziotis, P., Westin, H., Lauritzen, M., Koole, M., Herth, Matthias Manfred, Bardiès, M., Martins, A. F., Paulo, A., Lyashchenko, S. K., Todde, S., Nag, S., Lamprou, E., Abrunhosa, A., Giammarile, F. & Decristoforo, C., 2022, In: EJNMMI Radiopharmacy and Chemistry. 7, 1, 18.

    Research output: Contribution to journalReviewResearchpeer-review

  102. Published

    Prenatal nicotine alters development of the laterodorsal tegmentum: Possible role for attention-deficit/hyperactivity disorder and drug dependence

    Polli, F. S. & Kohlmeier, Kristi Anne, 2022, In: World journal of psychiatry. 12, 2, p. 212-235

    Research output: Contribution to journalReviewResearchpeer-review

  103. Published

    Preterm birth, stillbirth and early neonatal mortality during the Danish COVID-19 lockdown

    Hedley, P. L., Hedermann, G., Hagen, C. M., Bækvad-Hansen, M., Hjalgrim, Henrik, Rostgaard, K., Laksafoss, A. D., Hoffmann, S., Jensen, J. S., Breindahl, M., Melbye, Mads, Hviid, Anders Peter, Hougaard, D. M., Krebs, Lone, Lausten-Thomsen, U. & Christiansen, M., 2022, In: European Journal of Pediatrics. 181, p. 1175–1184

    Research output: Contribution to journalJournal articleResearchpeer-review

  104. Published

    Prevention of Cell Death by Activation of Hydroxycarboxylic Acid Receptor 1 (GPR81) in Retinal Explants

    Vohra, Rupali, Sanz-Morello, B., Tams, A. L. M., Mouhammad, Zaynab Ahmad, Freude, Kristine, Hannibal, Jens, Aldana, Blanca, Bergersen, Linda Hildegard & Kolko, Miriam, 2022, In: Cells. 11, 13, 2098.

    Research output: Contribution to journalJournal articleResearchpeer-review

  105. Published

    Production and characterization of peptide antibodies to the C-terminal of frameshifted calreticulin associated with myeloproliferative diseases

    Mughal , F. P., Bergmann , A. C., Huynh , H. U. B., Jørgensen, S. H., Mansha , I., Kesmeh , M., Schürch, P. M., Theocharides, A. P. A., Hansen, Paul Robert, Friis , T., Holmeren , M. Ö., Ciplys , E., Slibinskas , R., Højrup, P., Houen, G. & Trier, N. H., 2022, In: International Journal of Molecular Sciences. 23, 12, 21 p., 6803.

    Research output: Contribution to journalJournal articleResearchpeer-review

  106. Published

    Progressive Mitochondrial Dysfunction of Striatal Synapses in R6/2 Mouse Model of Huntington's Disease

    Petersen, M. H., Willert, C. W., Andersen, Jens Velde, Madsen, M., Waagepetersen, H. S., Skotte, N. H. & Nørremølle, Anne, 2022, In: Journal of Huntington's disease. 11, 2, p. 121-140

    Research output: Contribution to journalJournal articleResearchpeer-review

  107. Accepted/In press

    Proteomic phenotype of cerebral organoids derived from autism spectrum disorder patients reveal disrupted energy metabolism, cellular components, and biological processes

    Ilieva, M., Aldana, Blanca, Vinten, K. T., Hohmann, S., Woofenden, T. W., Lukjanska, R., Waagepetersen, H. S. & Michel, T. M., 2022, (Accepted/In press) In: Molecular Psychiatry.

    Research output: Contribution to journalJournal articleResearchpeer-review

  108. Published

    Psychopharmacological treatment patterns prior to a schizophrenia diagnosis: A Danish nationwide study

    Rohde, C., Højlund, M., Gasse, C., Hauser, Alexander Sebastian, Petersen, L. V., Christensen, R. H., Benros, M. E., Hallas, J., Mors, O. & Köhler-Forsberg, O., 2022, In: Schizophrenia Research. 246, p. 268-276

    Research output: Contribution to journalJournal articleResearchpeer-review

  109. Published

    Radiolabeling of a polypeptide polymer for intratumoral delivery of alpha-particle emitter, 225Ac, and beta-particle emitter, 177Lu

    Shalgunov, Vladimir, Engudar, G., Bohrmann, L., Wharton, L., Maskell, K., Johann, K., Barz, M., Schaffer, P., Herth, Matthias Manfred & Radchenko, V., 2022, In: Nuclear Medicine and Biology. 104-105, p. 11-21

    Research output: Contribution to journalJournal articleResearchpeer-review

  110. Published

    Rates of pyruvate carboxylase, glutamate and GABA neurotransmitter cycling, and glucose oxidation in multiple brain regions of the awake rat using a combination of [2-13C]/[1-13C]glucose infusion and 1H-[13C]NMR ex vivo

    McNair, Laura M., Mason, G. F., Chowdhury, G. M. I., Jiang, L., Ma, X., Rothman, D. L., Waagepetersen, H. S. & Behar, K. L., 2022, In: Journal of Cerebral Blood Flow and Metabolism. 42, 8, p. 1507–1523

    Research output: Contribution to journalJournal articleResearchpeer-review

  111. Published

    Rationale and performances of a data-driven method for computing the duration of pharmacological prescriptions using secondary data sources

    Pazzagli, L., Liang, D., Andersen, Morten, Linder, M., Khan, A. R. & Sessa, Maurizio, 2022, In: Scientific Reports. 12, 1, 8 p., 6245.

    Research output: Contribution to journalJournal articleResearchpeer-review

  112. Published

    Reactivity of Rheumatoid Arthritis-Associated Citrulline-Dependent Antibodies to Epstein-Barr Virus Nuclear Antigen1-3

    Fanelli, I., Rovero, P., Hansen, Paul Robert, Frederiksen, J. L., Houen, G. & Trier, N. H., 2022, In: Antibodies. 11, 1, 15 p., 20.

    Research output: Contribution to journalJournal articleResearchpeer-review

  113. Published

    Recent Advances in the Development of Tetrazine Ligation Tools for Pretargeted Nuclear Imaging

    García Vázquez, Rocío, Battisti, Umberto Maria & Herth, Matthias Manfred, 2022, In: Pharmaceuticals. 15, 6, 25 p., 685.

    Research output: Contribution to journalReviewResearchpeer-review

  114. Published

    Recommendations for addressing the translational gap between experimental and clinical research on amyloid diseases

    Solomon, M., Foderà, Vito, Langkilde, Annette Eva, Elliott, P., Tagliavini, F., Forsyth, V. T., Klementieva, O. & Bellotti, V., 2022, In: Journal of Translational Medicine. 20, 1, 7 p., 213.

    Research output: Contribution to journalJournal articleResearchpeer-review

  115. Published

    Reply to: "Impact of MELD 30-allocation policy on liver transplant outcomes in Italy: Considerations"

    Sessa, Maurizio, Lai, Q., Germinario, G. & Ravaioli, M., 2022, In: Journal of Hepatology. 77, 2, p. 573-574

    Research output: Contribution to journalLetterResearchpeer-review

  116. Accepted/In press

    Risk factors for granulomas in children following immunization with aluminium-adsorbed vaccines: A Danish population-based cohort study

    Hoffmann, S. S., Thiesson, E. M., Johansen, Jeanne Duus & Hviid, Anders Peter, 2022, (Accepted/In press) In: Contact Dermatitis.

    Research output: Contribution to journalJournal articleResearchpeer-review

  117. Published

    SARS-CoV-2 Vaccination and Myocarditis in a Nordic Cohort Study of 23 Million Residents

    Karlstad, Ø., Hovi, P., Husby, A., Härkänen, T., Selmer, R. M., Pihlström, N., Hansen, J. V., Nohynek, H., Gunnes, N., Sundström, A., Wohlfahrt, J., Nieminen, T. A., Grünewald, M., Gulseth, H. L., Hviid, Anders Peter & Ljung, R., 2022, In: JAMA Cardiology. 7, 6, p. 600-612

    Research output: Contribution to journalJournal articleResearchpeer-review

  118. Published

    Segmental Ureterectomy Versus Radical Nephroureterectomy in Older Patients Treated for Upper Tract Urothelial Carcinoma

    Abrate, A., Sessa, F., Sessa, Maurizio, Campi, R., Sebastianelli, A., Varca, V., Pavone, C., Vella, M., Bartoletti, R., Ficarra, V., Serni, S., Brunocilla, E., Gregori, A., Trombetta, C., Lissiani, A., Terrone, C., Gontero, P., Schiavina, R., Gacci, M. & Simonato, A., 2022, In: Clinical Genitourinary Cancer. 20, 4, p. 381-387

    Research output: Contribution to journalJournal articleResearchpeer-review

  119. Accepted/In press

    Serious arrhythmia in initiators of citalopram, escitalopram, and other selective serotonin reuptake inhibitors: A population-based cohort study in older adults

    Aakjær, Mia, Werther, S. K., De Bruin, M. L. & Andersen, Morten, 2022, (Accepted/In press) In: Clinical and Translational Science.

    Research output: Contribution to journalJournal articleResearchpeer-review

  120. Published

    Serrulatane diterpenoids from the leaves of Eremophila glabra and their potential as antihyperglycemic drug leads

    Petersen, M. J., Liang, C., Kjaerulff, Louise, Ndi, C., Semple, S., Buirchell, B., Coriani, S., Møller, Birger Lindberg & Stærk, Dan, 2022, In: Phytochemistry. 196, 11 p., 113072.

    Research output: Contribution to journalJournal articleResearchpeer-review

  121. Published

    Sex differences and caffeine impact in adenosine-induced hyperemia

    Lassen, M. L., Byrne, C., Sheykhzade, Majid, Wissenberg, M., Hurry, P. K., Schmedes, A. V., Kjær, Andreas & Hasbak, P., 2022, In: Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 63, 3, p. 431-437 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  122. Published

    Sex differences in the vulnerability of the hippocampus to prenatal stress

    Soti, M., Ranjbar, H., Kohlmeier, Kristi Anne & Shabani, M., 2022, In: Developmental Psychobiology. 64, 7, e22305.

    Research output: Contribution to journalJournal articleResearchpeer-review

  123. Published

    Sex-related differences within sleep-wake dynamics, cataplexy, and EEG fast-delta power in a narcolepsy mouse model

    Petersen, Louise Piilgaard, Rose, Laura, Hviid, C. G., Kohlmeier, Kristi Anne & Kornum, Birgitte Rahbek, 2022, In: Sleep. 45, 7, 15 p., zsac058.

    Research output: Contribution to journalJournal articleResearchpeer-review

  124. Published

    Sleep-controlling neurons are sensitive and vulnerable to multiple forms of alpha-synuclein: implications for the early appearance of sleeping disorders in alpha-synucleinopathies

    Brito dos Santos, Altair, Skaanning, L. K., Thaneshwaran, S., Mikkelsen, E., Leguizamon, Cesar Ramon Romero, Pedersen, T. S., Kristensen, M., Langkilde, Annette Eva & Kohlmeier, Kristi Anne, 2022, In: Cellular and Molecular Life Sciences. 79, 450.

    Research output: Contribution to journalJournal articleResearchpeer-review

  125. Published

    Sodium-Glucose Cotransporter 2 Inhibitors and Risk of Bladder and Renal Cancer: Scandinavian Cohort Study

    Ueda, P., Svanström, H., Hviid, Anders Peter, Eliasson, B., Svensson, A., Franzén, S., Gudbjörnsdottir, S., Hveem, K., Jonasson, C., Wintzell, V., Melbye, Mads & Pasternak, B., 2022, In: Diabetes Care. 45, 5, p. e93-e96

    Research output: Contribution to journalLetterResearchpeer-review

  126. Published

    Somatostatin venom analogs evolved by fish-hunting cone snails: From prey capture behavior to identifying drug leads

    Ramiro, Iris Bea L. , Bjørn-Yoshimoto, Walden, Imperial, J. S., Gajewiak, J., Salcedo, P. F., Watkins, M., Taylor, D., Resager, W., Ueberheide, B., Bräuner-Osborne, Hans, Whitby, F. G., Hill, C. P., Martin, L. F., Patwardhan, A., Concepcion, G. P., Olivera, B. M. & Safavi-Hemami, H., 2022, In: Science Advances. 8, 12, 16 p., eabk1410.

    Research output: Contribution to journalJournal articleResearchpeer-review

  127. Published

    Sphingolipid changes in Parkinson L444P GBA mutation fibroblasts promote α-synuclein aggregation

    Galvagnion-Büll, Céline, Marlet, Frederik Ravnkilde, Cerri, S., Schapira, A. H. V., Blandini, F. & Di Monte, D. A., 2022, In: Brain. 145, 3, p. 1038-1051

    Research output: Contribution to journalJournal articleResearchpeer-review

  128. Published

    Status of Planned and Ongoing Paediatric Trials Investigating COVID-19 Vaccines: A Cross-Sectional Study of Paediatric Clinical Trials Planned in Agreed PIPs and/or Registered in Clinical Trial Databases

    Christiansen, H., Thirstrup, Steffen & Hallgreen, Christine Erikstrup, 2022, In: Therapeutic Innovation & Regulatory Science. 56, p. 474–482

    Research output: Contribution to journalJournal articleResearchpeer-review

  129. Published

    Structural Determinants in the Staphylococcus aureus-Derived Phenol-Soluble Modulin α2 Peptide Required for Neutrophil Formyl Peptide Receptor Activation.

    Viklund, M., Fredriksson, J., Holdfeldt, A., Lind, S., Franzyk, Henrik, Dahlgren, C., Sundqvist, M. & Forsman, H., 2022, In: Journal of Immunology. 208, 7, p. 1632-1641

    Research output: Contribution to journalJournal articleResearchpeer-review

  130. Published

    Structural Insights into the Substrate Transport Mechanisms in GTR Transporters through Ensemble Docking

    Peña‐Varas, C., Kanstrup, Christa, Vergara‐jaque, A., González‐avendaño, M., Crocoll, C., Mirza, Osman Asghar, Dreyer, I., Nour-Eldin, Hussam Hassan & Ramírez, D., 2022, In: International Journal of Molecular Sciences. 23, 3, 20 p., 1595.

    Research output: Contribution to journalJournal articleResearchpeer-review

  131. Published

    Structural architecture of the human NALCN channelosome

    Kschonsak, M., Chua, Han Chow, Weidling, Claudia, Chakouri, N., Noland, C. L., Schott, K., Chang, T., Tam, C., Patel, N., Arthur, C. P., Leitner, A., Ben-Johny, M., Ciferri, C., Pless, Stephan & Payandeh, J., 2022, In: Nature. 603, p. 180–186

    Research output: Contribution to journalJournal articleResearchpeer-review

  132. Published

    Structural basis for modulation of human NaV1.3 by clinical drug and selective antagonist

    Li, X., Xu, F., Xu, H., Zhang, S., Gao, Y., Zhang, H., Dong, Y., Zheng, Y., Yang, B., Sun, J., Zhang, X. C., Zhao, Y. & Jiang, D., 2022, In: Nature Communications. 13, 1, 10 p., 1286.

    Research output: Contribution to journalJournal articleResearchpeer-review

  133. Published

    Structural basis for positive allosteric modulation of AMPA and kainate receptors

    Frydenvang, Karla Andrea, Pickering, Darryl S & Kastrup, Jette Sandholm Jensen, 2022, In: The Journal of Physiology. 600, 2, p. 181-200

    Research output: Contribution to journalReviewResearchpeer-review

  134. Published

    Structure-guided unlocking of NaX reveals a non-selective tetrodotoxin-sensitive cation channel

    Noland, C. L., Chua, Han Chow, Kschonsak, M., Heusser, Stephanie, Braun, Nina, Chang, T., Tam, C., Tang, J., Arthur, C. P., Ciferri, C., Pless, Stephan & Payandeh, J., 2022, In: Nature Communications. 13, 1, 10 p., 1416.

    Research output: Contribution to journalJournal articleResearchpeer-review

  135. E-pub ahead of print

    Strychnine and its mono- and dimeric analogues: a pharmaco-chemical perspective

    Zlotos, D. P., Mandour, Y. M. & Jensen, Anders A., 2022, (E-pub ahead of print) In: Natural Product Reports.

    Research output: Contribution to journalReviewResearchpeer-review

  136. Published

    Synergistic Experimental and Computational Investigation of the Bioorthogonal Reactivity of Substituted Aryltetrazines

    Battisti, Umberto Maria, García Vázquez, Rocío, Svatunek, D., Herrmann, B., Löffler, A., Mikula, H. & Herth, Matthias Manfred, 2022, In: Bioconjugate Chemistry. 33, 4, p. 608-624

    Research output: Contribution to journalJournal articleResearchpeer-review

  137. Published

    Synthesis and Structure–Activity Relationships of Novel Non-Steroidal CYP17A1 Inhibitors as Potential Prostate Cancer Agents

    Wróbel, T. M., Rogova, O., Sharma, K., Velazquez, M. N. R., Pandey, A. V., Jørgensen, Flemming Steen, Arendrup, Frederic Schrøder, Andersen, Kasper Langebjerg & Björkling, F., 2022, In: Biomolecules. 12, 2, 165.

    Research output: Contribution to journalJournal articleResearchpeer-review

  138. Published

    Synthesis and cellular evaluation of click-chemistry probes to study the biological effects of alpha, beta-unsaturated carbonyls

    Morozzi, C., Sauerland, M., Gamon, Luke Francis, Manandhar, Asmita, Ulven, Trond & Davies, Michael J., 2022, In: Redox Biology. 52, 8 p., 102299.

    Research output: Contribution to journalJournal articleResearchpeer-review

  139. Published

    Synthesis of Lysophosphatidylcholine and Mixed Phosphatidylcholine

    Papangelis, Athanasios & Ulven, Trond, 2022, In: The Journal of Organic Chemistry. 87, 12, p. 8194–8197

    Research output: Contribution to journalJournal articleResearchpeer-review

  140. Published

    Synthesis of gamma-Aminobutyric Acid (GABA) Analogues Conformationally Restricted by Bicyclo[3.1.0]hexane/hexene or [4.1.0]Heptane/heptene Backbones as Potent Betaine/GABA Transporter Inhibitors

    Mitsui, K., Lie, M. E. K., Saito, N., Fujiwara, K., Watanabe, M., Wellendorph, Petrine & Shuto, S., 2022, In: Organic Letters. 24, 23, p. 4151-4154

    Research output: Contribution to journalJournal articleResearchpeer-review

  141. Published

    Synthesis of phenol derivatives from cyclopentenones with arynes as key intermediates

    Telese, D., Staudt, Markus & Bunch, Lennart, 2022, In: Results in Chemistry. 4, 7 p., 100412.

    Research output: Contribution to journalJournal articleResearchpeer-review

  142. Published

    The Binding of Alpinia galanga Oil and Its Nanoemulsion to Mammal GABA(A) Receptors Using Rat Cortical Membranes and an In Silico Modeling Platform

    Khumpirapang, N., Suknuntha, K., Wongrattanakamon, P., Jiranusornkul, S., Anuchapreeda, S., Wellendorph, Petrine, Mullertz, Anette , Rades, Thomas & Okonogi, S., 2022, In: Pharmaceutics. 14, 3, 15 p., 650.

    Research output: Contribution to journalJournal articleResearchpeer-review

  143. Published

    The G protein database, GproteinDb

    Pandy-Szekeres, G., Esguerra, M., Hauser, Alexander Sebastian, Caroli, J., Munk, C., Pilger, S., Keseru, G. M., Kooistra, Albert Jelke & Gloriam, David E., 2022, In: Nucleic Acids Research. 50, D1, p. D518-D525

    Research output: Contribution to journalJournal articleResearchpeer-review

  144. Published

    The Location of Missense Variants in the Human GIP Gene Is Indicative for Natural Selection

    Lindquist, P., Gasbjerg, Lærke Smidt, Mokrosinski, J., Holst, Jens Juul, Hauser, Alexander Sebastian & Rosenkilde, Mette, 2022, In: Frontiers in Endocrinology. 13, 14 p., 891586.

    Research output: Contribution to journalJournal articleResearchpeer-review

  145. Published

    The PHARMACOM-EPI framework for integrating pharmacometric modelling into pharmacoepidemiological research using real-world data: application to assess death associated with valproate

    Soeorg, H., Sverrisdóttir, Eva, Andersen, Morten, Lund, Trine Meldgaard & Sessa, Maurizio, 2022, In: Clinical Pharmacology and Therapeutics. 111, 4, p. 840-856

    Research output: Contribution to journalJournal articleResearchpeer-review

  146. Published

    The Relationship Between Valproate and Lamotrigine/Levetiracetam Use and Prognosis in Patients With Epilepsy and Heart Failure: A Danish Register-Based Study

    Liang MPharm, D., Gardella, E., Kragholm, K., Polcwiartek, C. & Sessa, Maurizio, 2022, In: Journal of Cardiac Failure. 28, 4, p. 630-638

    Research output: Contribution to journalJournal articleResearchpeer-review

  147. Published

    The Relationship between Timing of Pretransplant Kidney Biopsy, Graft Loss, and Survival in Kidney Transplantation: An Italian Cohort Study

    Odaldi, F., Serenari, M., Comai, G., La Manna, G., Bova, R., Frascaroli, G., Malvi, D., Maroni, L., Vasuri, F., Germinario, G., Baraldi, O., Capelli, I., Cuna, V., Sangiorgi, G., D'Errico, A., Del Gaudio, M., Bertuzzo, V. R., Zanfi, C., Sessa, Maurizio & Ravaioli, M., 2022, In: Nephron. 146, 1, p. 22–31

    Research output: Contribution to journalJournal articleResearchpeer-review

  148. Published

    The comparative cardiovascular and renal effectiveness of sodium-glucose co-transporter-2 inhibitors and glucagon-like peptide-1 receptor agonists: A Scandinavian cohort study

    Ueda, P., Wintzell, V., Dahlqwist, E., Eliasson, B., Svensson, A. M., Franzén, S., Gudbjörnsdottir, S., Hveem, K., Jonasson, C., Melbye, Mads, Hviid, Anders Peter, Svanström, H. & Pasternak, B., 2022, In: Diabetes, Obesity and Metabolism. 24, 3, p. 473-485

    Research output: Contribution to journalJournal articleResearchpeer-review

  149. Published

    The physicochemical properties of preserved and preservative-free latanoprost eye drops and their impact on human conjunctival goblet cells

    Müllertz, O. A. O., Nagstrup, A. H., Mouhammad, Zaynab Ahmad, Freiberg, Josefine Clement, Nagymihály, R., Jacobsen, Jette, Larsen, Susan Weng, Bair, J. A., Utheim, T. P., Dartt, D. A., Heegaard, Steffen, Petrovski, G. & Kolko, Miriam, 2022, In: Acta Ophthalmologica. 100, S267

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  150. Published

    The suitability of high throughput automated patch clamp for physiological applications

    Obergrussberger, A., Rinke-Weiß, I., Goetze, T. A., Rapedius, M., Brinkwirth, N., Becker, N., Rotordam, M. G., Hutchison, L., Madau, P., Pau, D., Dalrymple, D., Braun, Nina, Friis, S., Pless, Stephan & Fertig, N., 2022, In: Journal of Physiology. 600, 2, p. 277-297

    Research output: Contribution to journalJournal articleResearchpeer-review

  151. Published

    Transition Metal-Free Synthesis of meta-Bromo- and meta-Trifluoromethylanilines from Cyclopentanones by a Cascade Reaction

    Staudt, Markus, Cetin, A. & Bunch, Lennart, 2022, In: Chemistry: A European Journal. 28, 10, 5 p., 202102998.

    Research output: Contribution to journalJournal articleResearchpeer-review

  152. Published

    Tritium hydrogen-isotope exchange with electron-poor tertiary benzenesulfonamide moiety; application in late-stage labeling of T0901317

    Tian, Yongsong, Broz, B., Turecek, F. & Marek, A., 2022, In: Journal of Labelled Compounds and Radiopharmaceuticals. 65, 2, p. 36-44

    Research output: Contribution to journalJournal articleResearchpeer-review

  153. Published

    Vagal afferent cholecystokinin receptor activation is required for glucagon-like peptide-1–induced satiation

    Vana, Vasiliki, Lærke, M. K., Rehfeld, Jens Frederik, Arnold, M., Dmytriyeva, O., Langhans, W., Schwartz, Thue W. & Hansen, Harald S., 2022, In: Diabetes, Obesity and Metabolism. 24, 2, p. 268-280

    Research output: Contribution to journalJournal articleResearchpeer-review

  154. Published

    Wie Rezeptormutationen Arzneimittelwirkungen beeinflussen können

    Reiner-Link, David & Hauser, Alexander Sebastian, 2022, In: BioSpektrum. 28, 2, p. 140-143

    Research output: Contribution to journalComment/debateResearchpeer-review

  155. Published

    [11C]Carboxylated Tetrazines for Facile Labeling of Trans-Cyclooctene-Functionalized PeptoBrushes

    García Vázquez, Rocío, Battisti, Umberto Maria, Shalgunov, Vladimir, Schäfer, G., Barz, M. & Herth, Matthias Manfred, 2022, In: Macromolecular Rapid Communications. 43, 12, 7 p., 2100655.

    Research output: Contribution to journalJournal articleResearchpeer-review

  156. 2021
  157. Published

    The impact of folding modes and deuteration on the atomic resolution structure of hen egg-white lysozyme

    Ramos, J., Laux, V., Haertlein, M., Forsyth, V. T., Mossou, E., Larsen, Sine & Langkilde, Annette Eva, 1 Dec 2021, In: Acta crystallographica Section D: Structural biology . 77, 12, p. 1579-1590 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  158. Published

    Dendrimer end-terminal motif-dependent evasion of human complement and complement activation through IgM hitchhiking

    Wu, L. P., Ficker, M., Christensen, Jørn Bolstad, Simberg, D., Trohopoulos, P. N. & Moghimi, S. M., Dec 2021, In: Nature Communications. 12, 1, 13 p., 4858.

    Research output: Contribution to journalJournal articleResearchpeer-review

  159. Published

    Prenatal exposure to nicotine in mice is associated with alterations in development and cellular and synaptic effects of alcohol in a brainstem arousal nucleus

    Nunes-Freitas, A. L., Soni, N., Polli, F. S. & Kohlmeier, Kristi Anne, 1 Sep 2021, In: Neurotoxicology and Teratology. 87, 106980.

    Research output: Contribution to journalJournal articleResearchpeer-review

  160. Published

    A nationwide study of Chlamydia trachomatis infections in Denmark during the COVID-19 pandemic

    Hedley, P. L., Hoffmann, S., Lausten-Thomsen, U., Voldstedlund, M., Bjerre, K. D., Hviid, Anders Peter, Krebs, Lone, Jensen, J. S. & Christiansen, M., 6 Jul 2021, medRxiv, 22 p.

    Research output: Working paperPreprintResearch

  161. Published

    The effect of the molecular weight of polyvinylpyrrolidone and the model drug on laser-induced in situ amorphization

    Hempel, N. J., Merkl, P., Knopp, M. M., Berthelsen, Ragna, Teleki, A., Hansen, A. K., Sotiriou, G. A. & Löbmann, Korbinian, Jul 2021, In: Molecules. 26, 13, 13 p., 4035.

    Research output: Contribution to journalJournal articleResearchpeer-review

  162. Published

    Insects as sources for sustainable peptide drugs against type 2 diabetes

    Didriksen, A. H., Petersen, M. J. & Stærk, Dan, 8 Jun 2021. 1 p.

    Research output: Contribution to conferencePosterResearch

  163. Published

    α-Glucosidase inhibitory activity of plant extracts from the Danish Medicinal Plant Biobank

    Madsen, A. T., Soelberg, Jens & Stærk, Dan, 8 Jun 2021. 1 p.

    Research output: Contribution to conferencePosterResearch

  164. Published

    Positive allosteric modulators of metabotropic glutamate receptor 5 as tool compounds to study signaling bias

    Arsova, A., Møller, T. C., Hellyer, S. D., Vedel, L., Foster, S. R., Hansen, J. L., Bräuner-Osborne, Hans & Gregory, K. J., 1 May 2021, In: Molecular Pharmacology. 99, 5, p. 328-241

    Research output: Contribution to journalJournal articleResearchpeer-review

  165. Published

    Structural Determinants for the Mode of Action of Imidazopyridine DS2 at δ-Containing γ-Aminobutyric Acid Type A Receptors

    Rostrup, F., Falk-petersen, C. B., Harpsøe, Kasper, Buchleithner, S., Conforti, I., Jung, S., Gloriam, David E., Schirmeister, T., Wellendorph, Petrine & Frølund, Bente, 22 Apr 2021, In: Journal of Medicinal Chemistry. 64, 8, p. 4730-4743 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  166. Published

    Selection criteria for early breast cancer patients in the DBCG proton trial - The randomised phase III trial strategy

    Stick, L. B., Lorenzen, E. L., Yates, E. S., Anandadas, C., Andersen, K., Aristei, C., Byrne, O., Hol, S., Jensen, I., Kirby, A. M., Kirova, Y. M., Marrazzo, L., Matias-Perez, A., Nielsen, M. M. B., Nissen, H. D., Oliveros, S., Verhoeven, K., Vikstrom, J. & Offersen, B. V., Mar 2021, In: Clinical and Translational Radiation Oncology. 27, p. 126-131 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  167. Published

    Discovery of Diaryl Ether Substituted Tetrahydrophthalazinones as TbrPDEB1 Inhibitors Following Structure-Based Virtual Screening

    de Heuvel, E., Kooistra, Albert Jelke, Edink, E., van Klaveren, S., Stuijt, J., van der Meer, T., Sadek, P., Mabille, D., Caljon, G., Maes, L., Siderius, M., de Esch, I. J. P., Sterk, G. J. & Leurs, R., 21 Jan 2021, In: Frontiers in Chemistry. 8, 10 p., 608030.

    Research output: Contribution to journalJournal articleResearchpeer-review

  168. Published

    Artificial Intelligence in Pharmacoepidemiology: A Systematic Review. Part 2–Comparison of the Performance of Artificial Intelligence and Traditional Pharmacoepidemiological Techniques

    Sessa, Maurizio, Liang, D., Khan, A. R., Kulahci, M. & Andersen, Morten, 14 Jan 2021, In: Frontiers in Pharmacology. 11, 10 p., 568659.

    Research output: Contribution to journalReviewResearchpeer-review

  169. Published

    Hydroxamic acid-modified peptide microarrays for profiling isozyme-selective interactions and inhibition of histone deacetylases

    Moreno Yruela, Carlos, Bæk, M., Vrsanova, A., Schulte, C., Maric, H. M. & Olsen, Christian Adam, 4 Jan 2021, In: Nature Communications. 12, 1

    Research output: Contribution to journalJournal articleResearchpeer-review

  170. Published

    25CN-NBOH: A selective agonist for in vitro and in vivo investigations of the serotonin 2A receptor

    Marcher, Emil, Jensen, Anders A. & Kristensen, Jesper Langgaard, 2021, In: ChemMedChem. 16, 21, p. 3263-3270

    Research output: Contribution to journalReviewResearchpeer-review

  171. Published

    A Comprehensive RNA Study to Identify circRNA and miRNA Biomarkers for Docetaxel Resistance in Breast Cancer

    Huang, P., Li, F., Mo, Z., Geng, C., Wen, F., Zhang, C., Guo, J., Wu, S., Li, L., Brünner, Nils & Stenvang, Jan, 2021, In: Frontiers in Oncology. 11, 14 p., 669270.

    Research output: Contribution to journalJournal articleResearchpeer-review

  172. Published

    A High-Affinity Peptide Ligand Targeting Syntenin Inhibits Glioblastoma

    Haugaard-Kedstrom, L. M., Clemmensen, L. S., Sereikaité, Vita, Jin, Z., Alves Fernandes, Eduardo Felipe, Wind, B., Abalde-Gil, F., Daberger, J., Vistrup-Parry, Maria, Aguilar-Morante, D., Leblanc, R., Egea-Jimenez, A. L., Albrigtsen, M., Jensen, K. E., Jensen, T. M. T., Ivarsson, Y., Vincentelli, R., Hamerlík, Petra, Andersen, J. H., Zimmermann, P., Lee, W. & Strømgaard, Kristian, 2021, In: Journal of Medicinal Chemistry. 64, 3, p. 1423-1434 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  173. Published

    A Scoping Review of Quality of Life Questionnaires in Glaucoma Patients

    Gazzard, G., Kolko, Miriam, Iester, M. & Crabb, D. P., 2021, In: Journal of Glaucoma. 30, 8, p. 732-743

    Research output: Contribution to journalReviewResearchpeer-review

  174. Published

    A common data model for harmonization in the nordic pregnancy drug safety studies (Norpress)

    Cohen, J. M., Cesta, C. E., Kjerpeseth, L., Leinonen, M. K., Hálfdánarson, Ó., Karlstad, Ø., Karlsson, P., Andersen, Morten, Furu, K. & Hjellvik, V., 2021, In: Norsk Epidemiologi. 29, 1-2, p. 117-123

    Research output: Contribution to journalJournal articleResearchpeer-review

  175. Published

    A conformational change of complement C5 is required for thrombin-mediated cleavage, revealed by a novel ex vivo human whole blood model preserving full thrombin activity

    Nilsson, P. H., Johnson, C., Quach, Q. H., Macpherson, A., Durrant, O., Pischke, S. E., Fure, H., Landsem, A., Bergseth, G., Schjalm, C., Haugaard-Kedström, L. M., Huber-Lang, M., van den Elsen, J., Brekke, O. L. & Mollnes, T. E., 2021, In: Journal of Immunology. 207, 6, p. 1641-1651

    Research output: Contribution to journalJournal articleResearchpeer-review

  176. Published

    A novel red fluorescence dopamine biosensor selectively detects dopamine in the presence of norepinephrine in vitro

    Nakamoto, C., Goto, Y., Tomizawa, Y., Fukata, Y., Fukata, M., Harpsøe, Kasper, Gloriam, David E., Aoki, K. & Takeuchi, T., 2021, In: Molecular Brain. 14, 1, 14 p., 173.

    Research output: Contribution to journalJournal articleResearchpeer-review

  177. Published

    A quantitative method for the selective 5-HT2A agonist 25CN-NBOH in rat plasma and brain

    Breusova, K., Ernstsen, K. G., Palner, M., Linnet, Kristian, Kristensen, Jesper Langgaard & Kretschmann, A. C., 2021, In: Journal of Pharmaceutical and Biomedical Analysis. 199, 114016.

    Research output: Contribution to journalJournal articleResearchpeer-review

  178. Published

    A systematic review and meta-analysis of cannabis-based medicines, cannabinoids and endocannabinoid system modulators tested for antinociceptive effects in animal models of injury-related or pathological persistent pain

    Soliman, N., Haroutounian, S., Hohmann, A. G., Krane, E., Liao, J., Macleod, M., Segelcke, D., Sena, C., Thomas, J., Vollert, J., Wever, K., Alaverdyan, H., Barakat, Ahmed, Barthlow, T., Harris Bozer, A. L., Davidson, A., Diaz del Castillo, Marta, Dolgorukova, A., Ferdousi, M. I., Healy, C., Hong, S., Hopkins, M., James, A., Leake, H. B., Malewicz, N. M., Mansfield, M., Mardon, A. K., Mattimoe, D., Mcloone, D. P., Noes-Holt, Gith, Pogatzki-zahn, E. M., Power, E., Pradier, B., Romanos-sirakis, E., Segelcke, A., Vinagre, R., Yanes, J. A., Zhang, J., Zhang, X. Y., Finn, D. P. & Rice, A. S. C., 2021, In: Pain. 162, p. S26-S44 19 p.

    Research output: Contribution to journalReviewResearchpeer-review

  179. Published

    A systematic review of possible interactions for herbal medicines and dietary supplements used concomitantly with disease-modifying or symptom-alleviating multiple sclerosis drugs

    Petersen, M. J., Bergien, Sofie Olsgaard & Stærk, Dan, 2021, In: Phytotherapy Research. 35, 7, p. 3610-3631

    Research output: Contribution to journalJournal articleResearchpeer-review

  180. Published

    A systematic review, meta-analysis and meta-regression evaluating the adverse reactions to erenumab in the preventive treatment of migraine

    Pellesi, L., De Icco, R., Alawie, H. Y., Andersen, Morten, Liang, D., Amirguliyev, S., Al-Karagholi, M. A., Amin, Faisal Mohammad & Sessa, Maurizio, 2021, In: Expert Opinion on Drug Safety. 20, 4, p. 467-474

    Research output: Contribution to journalReviewResearchpeer-review

  181. Published

    AMBRA1 regulates cyclin D to guard S-phase entry and genomic integrity

    Maiani, E., Milletti, G., Nazio, F., Holdgaard, S. G., Bartkova, J., Rizza, S., Cianfanelli, V., Lorente, M., Simoneschi, D., Di Marco, M., D'Acunzo, P., Di Leo, L., Rasmussen, R., Montagna, C., Raciti, M., De Stefanis, C., Gabicagogeascoa, E., Rona, G., Salvador, N., Pupo, E., Merchut-Maya, J. M., Daniel, C. J., Carinci, M., Cesarini, V., O'sullivan, A., Jeong, Y., Bordi, M., Russo, F., Campello, S., Gallo, A., Filomeni, G., Lanzetti, L., Sears, R. C., Hamerlík, Petra, Bartolazzi, A., Hynds, R. E., Pearce, D. R., Swanton, C., Pagano, M., Velasco, G., Papaleo, E., De Zio, D., Maya-Mendoza, A., Locatelli, F., Bartek, J. & Cecconi, F., 2021, In: Nature. 592, p. 799-803

    Research output: Contribution to journalJournal articleResearchpeer-review

  182. Published

    Acid-sensing ion channels as potential therapeutic targets

    Heusser, Stephanie & Pless, Stephan, 2021, In: Trends in Pharmacological Sciences. 42, 12, p. 1035-1050

    Research output: Contribution to journalReviewResearchpeer-review

  183. Published

    Acute effects of delayed-release hydrolyzed pine nut oil on glucose tolerance, incretins, ghrelin and appetite in healthy humans

    Sørensen, K. V., Korfitzen, S. S., Kaspersen, M. H., Ulven, Elisabeth Rexen, Ekberg, J. H., Bauer-Brandl, A., Ulven, Trond & Højlund, K., 2021, In: Clinical Nutrition. 40, 4, p. 2169-2179

    Research output: Contribution to journalJournal articleResearchpeer-review

  184. Published

    Addiction and the cerebellum with a focus on actions of opioid receptors

    Ranjbar, H., Soti, M., Banazadeh, M., Saleki, K., Kohlmeier, Kristi Anne & Shabani, M., 2021, In: Neuroscience and Biobehavioral Reviews. 131, p. 229-247

    Research output: Contribution to journalReviewResearchpeer-review

  185. Published

    Adherence to Direct Oral Anticoagulants in Patients With Non-Valvular Atrial Fibrillation: A Cross-National Comparison in Six European Countries (2008–2015)

    Sabaté, M., Vidal, X., Ballarin, E., Rottenkolber, M., Schmiedl, S., Grave, B., Huerta, C., Martin-Merino, E., Montero, D., Leon-Muñoz, L. M., Gasse, C., Moore, N., Droz, C., Lassalle, R., Aakjær, Mia, Andersen, Morten, De Bruin, M. L., Souverein, P., Klungel, O. H., Gardarsdottir, H. & Ibáñez, L., 2021, In: Frontiers in Pharmacology. 12, 14 p., 682890.

    Research output: Contribution to journalJournal articleResearchpeer-review

  186. Published

    Aliphatic 18F-Radiofluorination: Recent Advances in the Labeling of Base-Sensitive Substrates**

    Bratteby, K., Shalgunov, Vladimir & Herth, Matthias Manfred, 2021, In: ChemMedChem. 16, 17, p. 2612-2622

    Research output: Contribution to journalReviewResearchpeer-review

  187. Published

    Alpha-Synuclein PET tracer development-an overview about current efforts

    Korat, Š., Bidesi, Natasha Shalina Rajani, Bonanno, F., Di Nanni, A., Hoàng, A. N. N., Herfert, K., Maurer, A., Battisti, Umberto Maria, Bowden, G. D., Thonon, D., Vugts, D., Windhorst, A. D. & Herth, Matthias Manfred, 2021, In: Pharmaceuticals. 14, 9, 45 p., 847.

    Research output: Contribution to journalReviewResearchpeer-review

  188. Published

    Amide bond formation in aqueous solution: direct coupling of metal carboxylate salts with ammonium salts at room temperature

    Truong Thanh Tung & Nielsen, John, 2021, In: Organic & Biomolecular Chemistry. 19, p. 10073-10080

    Research output: Contribution to journalJournal articleResearchpeer-review

  189. Published

    An improved, scalable synthesis of the selective serotonin 2A receptor agonist 25CN-NBOH

    Marcher, Emil, Nykodemova, J. & Kristensen, Jesper Langgaard, 2021, In: SynOpen. 5, 2, p. 158-160

    Research output: Contribution to journalJournal articleResearchpeer-review

  190. Published

    An independent evolutionary origin for insect deterrent cucurbitacins in Iberis amara

    Dong, L., Almeida Robles, A. R., Pollier, J., Khakimov, Bekzod, Bassard, J. A., Miettinen, K., Stærk, Dan, Mehran, R., Olsen, C. E., Motawie, Mohammed Saddik, Goossens, A. & Bak, Søren, 2021, In: Molecular Biology and Evolution. 38, 11, p. 4659-4673 15 p., msab213.

    Research output: Contribution to journalJournal articleResearchpeer-review

  191. Published

    An online GPCR structure analysis platform

    Kooistra, Albert Jelke, Munk, C., Hauser, Alexander Sebastian & Gloriam, David E., 2021, In: Nature Structural and Molecular Biology. 28, 11, p. 875-878

    Research output: Contribution to journalJournal articleResearchpeer-review

  192. Published

    An in silico kinetic model of 8-oxo-7,8-dihydro-2-deoxyguanosine and 8-oxo-7,8-dihydroguanosine metabolism from intracellular formation to urinary excretion

    Jørgensen, Anders, Thygesen, M. B., Kristiansen, Uffe & Poulsen, Henrik Enghusen, 2021, In: Scandinavian Journal of Clinical and Laboratory Investigation. 81, 7, p. 540-545

    Research output: Contribution to journalJournal articleResearchpeer-review

  193. Published

    Antibiotic Potentiation in Multidrug-Resistant Gram-Negative Pathogenic Bacteria by a Synthetic Peptidomimetic

    Harifi Mood, Elnaz, Goltermann, L., Brolin, C., Cavaco, L. M., Japoni Nejad, Alireza, Yavari, Niloofar, Frederiksen, Nicki, Franzyk, Henrik & Nielsen, Peter E., 2021, In: ACS Infectious Diseases. 7, 8, p. 2152–2163

    Research output: Contribution to journalJournal articleResearchpeer-review

  194. Published

    Arrestin-Dependent and -Independent Internalization of G Protein–Coupled Receptors: Methods, Mechanisms, and Implications on Cell Signaling

    Moo, Ee Von, van Senten, Jeffrey Roy, Bräuner-Osborne, Hans & Møller, T. C., 2021, In: Molecular Pharmacology. 99, 4, p. 242-255

    Research output: Contribution to journalJournal articleResearchpeer-review

  195. Published

    Arterial events, venous thromboembolism, thrombocytopenia, and bleeding after vaccination with Oxford-AstraZeneca ChAdOx1-S in Denmark and Norway: Population based cohort study

    Pottegård, A., Lund, L. C., Karlstad, Ø., Dahl, J., Andersen, Morten, Hallas, J., Lidegaard, Øjvind, Tapia, G., Gulseth, H. L., Ruiz, P. L. D., Watle, S. V., Mikkelsen, A. P., Pedersen, L., Sørensen, H. T., Thomsen, R. W. & Hviid, Anders Peter, 2021, In: The BMJ. 373, 10 p., n1114.

    Research output: Contribution to journalJournal articleResearchpeer-review

  196. Published

    Artificial Intelligence and Cheminformatics-Guided Modern Privileged Scaffold Research

    Qiu, H., Clausen, Rasmus Prætorius, He, Y. & Zhu, H., 2021, In: Current Topics in Medicinal Chemistry. 21, 28, p. 2593-2608

    Research output: Contribution to journalReviewResearchpeer-review

  197. Published

    Association between Diabetic Retinopathy and Glaucoma: Results from a National Screening Program. A National Study

    Sperling, S., Stokholm, L., Andresen, J., Kolko, Miriam, Vestergaard, A. H. & Grauslund, J., 2021, In: European Journal of Ophthalmology. 31, 2_SUPPL, p. 5-6 2 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  198. Published

    Association between Human Papillomavirus Vaccination and Primary Ovarian Insufficiency in a Nationwide Cohort

    Hviid, Anders Peter & Myrup Thiesson, E., 2021, In: JAMA network open. 4, 8, 10 p., e2120391.

    Research output: Contribution to journalJournal articleResearchpeer-review

  199. Published

    Association between inhaled corticosteroid use and COVID-19 outcomes

    Husby, A., Pottegård, A. & Hviid, Anders Peter, 2021, In: Pharmacoepidemiology and Drug Safety. 30, 11, p. 1486-1492

    Research output: Contribution to journalJournal articleResearchpeer-review

  200. Published

    Astrocyte metabolism of the medium-chain fatty acids octanoic acid and decanoic acid promotes GABA synthesis in neurons via elevated glutamine supply

    Andersen, Jens Velde, Westi, E. W., Jakobsen, Emil, Urruticoechea, N., Borges, K. & Aldana, Blanca, 2021, In: Molecular Brain. 14, 1, 13 p., 132.

    Research output: Contribution to journalJournal articleResearchpeer-review

  201. Published

    Astrocytic reactivity triggered by defective autophagy and metabolic failure causes neurotoxicity in frontotemporal dementia type 3

    Chandrasekaran, Abinaya, Dittlau, K. S., Corsi, Giulia, Haukedal, Henriette, Doncheva, Nadezhda Tsankova, Ramakrishna, S., Ambardar, S., Salcedo, C., Schmidt, S. I., Zhang, Y., Cirera, Susanna, Pihl, M., Schmid, B., Nielsen, T. T., Nielsen, Jørgen Erik, Kolko, Miriam, Kobolák, J., Dinnyés, A., Hyttel, P., Palakodeti, D., Gorodkin, Jan, Muddashetty, R. S., Meyer, M., Aldana, Blanca & Freude, Kristine, 2021, In: Stem Cell Reports. 16, 11, p. 2736-2751

    Research output: Contribution to journalJournal articleResearchpeer-review

  202. Published

    Asymmetric activation of the calcium-sensing receptor homodimer

    Gao, Y., Robertson, M. J., Rahman, Sabrina Nalini, Seven, A. B., Zhang, C., Meyerowitz, J. G., Panova, O., Hannan, F. M., Thakker, R. V., Bräuner-Osborne, Hans, Mathiesen, Jesper M. & Skiniotis, G., 2021, In: Nature. 595, p. 455-459

    Research output: Contribution to journalJournal articleResearchpeer-review

  203. Published

    Benefits, risks and clinical practices related to augmentation of labour with oxytocin in low- and lower-middle-income countries: A systematic review

    Kujabi, Monica Lauridsen, Mikkelsen, E. F. R., Husseine, N., Hussein, K., van Roosmalen, J., Meyrowitsch, Dan Wolf, Obel, J., Konradsen, Flemming, van den Akker, T. & Maaloe, Nanna, 2021, In: Tropical Medicine & International Health. 26, Supplement 1, p. 226 1 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  204. Published

    Benzalkonium Chloride-Preserved Anti-Glaucomatous Eye Drops and Their Effect on Human Conjunctival Goblet Cells in vitro

    Hedengran, A., Begun, X., Müllertz, O., Mouhammad, Zaynab Ahmad, Vohra, Rupali, Bair, J., Dartt, D. A., Cvenkel, B., Heegaard, Steffen, Petrovski, G. & Kolko, Miriam, 2021, In: Biomedicine Hub. 6, 2, p. 69-75

    Research output: Contribution to journalJournal articleResearchpeer-review

  205. Published

    Biased cytochrome P450-mediated metabolism via small-molecule ligands binding P450 oxidoreductase

    Jensen, S. B., Thodberg, Sara, Parween, S., Moses, M. E., Hansen, Cecilie Ida Cetti, Thomsen, J., Sletfjerding, M. B., Knudsen, C., Del Giudice, R., Lund, P. M., Castaño, P. R., Bustamante, Y. G., Velazquez, M. N. R., Jørgensen, Flemming Steen, Pandey, A. V., Laursen, Tomas, Møller, Birger Lindberg & Hatzakis, Nikos, 2021, In: Nature Communications. 12, 1, 14 p., 2260.

    Research output: Contribution to journalJournal articleResearchpeer-review

  206. Published

    Bidirectional Association between Atopic Dermatitis, Conjunctivitis and other Ocular Surface Diseases: A Systemic Review and Meta-Analysis

    Ravn, N. H., Ahmadzay, Z. F., Christensen, T. A., Larsen, H. H. P., Loft, N., Hansen, Pernille May, Heegaard, Steffen, Kolko, Miriam, Egeberg, A., Silverberg, J. I., Halling, A. S. & Thyssen, Jacob Pontoppidan, 2021, In: Journal of the American Academy of Dermatology. 85, 2, p. 453-461

    Research output: Contribution to journalReviewResearchpeer-review

  207. Published

    Binding of a negative allosteric modulator and competitive antagonist can occur simultaneously at the ionotropic glutamate receptor GluA2

    Krintel, C., Dorosz, J., Larsen, A. H., Thorsen, Thor Seneca, Venskutonytė, R., Mirza, Osman Asghar, Gajhede, Michael, Boesen, T. & Kastrup, Jette Sandholm Jensen, 2021, In: The FEBS Journal. 288, p. 995-1007 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  208. Published

    Bone Pain in Multiple Myeloma (BPMM)—A Protocol for a Prospective, Longitudinal, Observational Study

    Diaz del Castillo, Marta, Andrews, R. E., Mandal, A., Andersen, T. L., Chantry, A. D. & Heegaard, Anne-Marie, 2021, In: Cancers. 13, 7, 13 p., 1596.

    Research output: Contribution to journalJournal articleResearchpeer-review

  209. Published

    Bounded Integer Modeling of Symptom Scales Specific to Lower Urinary Tract Symptoms Secondary to Benign Prostatic Hyperplasia

    Lyauk, Y. K., Jonker, D. M., Hooker, A., Lund, Trine Meldgaard & Karlsson, M. O., 2021, In: The AAPS journal. 23, 2, 14 p., 33.

    Research output: Contribution to journalJournal articleResearchpeer-review

  210. Published

    Brain endothelial cells metabolize glutamate via glutamate dehydrogenase to replenish TCA-intermediates and produce ATP under hypoglycemic conditions

    Hinca, S. B., Salcedo, C., Wagner, A., Goldeman, C., Sadat, E., Aibar, M. M. D., Maechler, P., Larsen, Birger Brodin, Aldana, Blanca & Helms, H. C. C., 2021, In: Journal of Neurochemistry. 157, 6, p. 1861-1875

    Research output: Contribution to journalJournal articleResearchpeer-review

  211. Published

    C-2-Linked Dimeric Strychnine Analogues as Bivalent Ligands Targeting Glycine Receptors

    Zlotos, D. P., Abdelmalek, C. M., Botros, L. S., Banoub, M. M., Mandour, Y. M., Breitinger, U., El Nady, A., Breitinger, H., Sotriffer, C., Villmann, C., Jensen, Anders A. & Holzgrabe, U., 2021, In: Journal of Natural Products. 84, 2, p. 382-394

    Research output: Contribution to journalJournal articleResearchpeer-review

  212. Published

    C-Terminal lactamization of peptides

    Fischer, Niklas Henrik, Nielsen, D. S., Palmer, D., Meldal, Morten Peter & Diness, Frederik, 2021, In: Chemical Communications. 57, 7, p. 895-898 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  213. Published

    Cannabinoid CB1 receptor mediates METH-induced electrophysiological and morphological alterations in cerebellum Purkinje cells

    Ramshini, E., Sheykhzade, Majid, Dabiri, S. & Shabani, M., 2021, In: Human & Experimental Toxicology. 40, 6, p. 940-951

    Research output: Contribution to journalJournal articleResearchpeer-review

  214. Published

    Capillary flow experiments for thermodynamic and kinetic characterization of protein liquid-liquid phase separation

    Stender, E. G. P., Ray, S., Norrild, R. K., Larsen, J. A., Petersen, Daniel, Farzadfard, A., Galvagnion-Büll, Céline, Jensen, H. & Buell, A. K., 2021, In: Nature Communications. 12, 1, 18 p., 7289.

    Research output: Contribution to journalJournal articleResearchpeer-review

  215. Published

    Cellular bioenergetics in human iPSC-derived glutamatergic neurons in health and disease

    Aldana, Blanca, Salcedo, C., Freude, Kristine & Waagepetersen, H. S., 2021, Current Progress in iPSC-derived Cell Types. Birbrair, A. (ed.). Elsevier, p. 205-221 17 p. (Advances in Stem Cell Biology, Vol. 10).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  216. Published
  217. Published

    Characterization of the multidrug efflux transporter styMdtMfrom Salmonella enterica serovar Typhi

    Shaheen, A., Ismat, F., Iqbal, M., Haque, A., Ul-Haq, Z., Mirza, Osman Asghar, De Zorzi, R., Walz, T. & Rahman, M., 2021, In: Proteins: Structure, Function, and Bioinformatics. 89, 9, p. 1193-1204

    Research output: Contribution to journalJournal articleResearchpeer-review

  218. Published

    Characterizing Conformational Changes of ASIC1a During Gating and Peptide Modulation

    Heusser, Stephanie, Sheikh, Zeshan Pervez, Borg, C. B., Galleano, Iacopo & Pless, Stephan, 2021, p. 337A-337A.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  219. Published

    Chemical Synthesis of PDZ Domains

    Kossmann, C., Ma, S., Clemmensen, L. S. & Strømgaard, Kristian, 2021, Methods in Molecular Biology. J-P. B. (ed.). Humana Press, p. 193-216 24 p. (Methods in Molecular Biology, Vol. 2256).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  220. Published

    Chemical Translational Biology: Redefining Druggability of Protein-Protein Interactions

    Cesa, L. C., 2021, In: ChemBioChem. 22, 6, p. 985-987

    Research output: Contribution to journalEditorialResearchpeer-review

  221. Published

    Chemical biology: A toolbox to unlock neurochemical epigenetics?

    Ozcelik, D., 2021, In: Neural Regeneration Research. 16, 2, p. 298-299

    Research output: Contribution to journalJournal articleResearchpeer-review

  222. Published

    Co-treatment of vitamin D supplementation with enriched environment improves synaptic plasticity and spatial learning and memory in aged rats

    Bayat, M., Kohlmeier, Kristi Anne, Haghani, M., Haghighi, A. B., Khalili, A., Bayat, G., Hooshmandi, E. & Shabani, M., 2021, In: Psychopharmacology. 238, p. 2297–2312

    Research output: Contribution to journalJournal articleResearchpeer-review

  223. Published

    Comparing risk of major bleeding between users of different oral anticoagulants in patients with nonvalvular atrial fibrillation

    Souverein, P. C., van den Ham, H. A., Huerta, C., Merino, E. M., Montero, D., Leon-Munoz, L. M., Schmiedl, S., Heeke, A., Rottenkolber, M., Andersen, Morten, Aakjær, Mia, De Bruin, M. L., Klungel, O. H. & Gardarsdottir, H., 2021, In: British Journal of Clinical Pharmacology. 87, 3, p. 988-1000

    Research output: Contribution to journalJournal articleResearchpeer-review

  224. Published

    Comparison of multidrug use in the general population and among persons with diabetes in denmark for drugs having pharmacogenomics (PGx) based dosing guidelines

    Westergaard, N., Tarnow, L. & Vermehren, Charlotte, 2021, In: Pharmaceuticals. 14, 9, 14 p., 899.

    Research output: Contribution to journalJournal articleResearchpeer-review

  225. Published

    Conformational Landscapes of Ligand-Gated Ion Channel GLIC from Markov State Modeling

    Bergh, C., Heusser, Stephanie, Howard, R. J. & Lindahl, E. R., 2021, p. 58A-58A.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  226. Published

    Coupling microplate-based antibacterial assay with liquid chromatography for high-resolution growth inhibition profiling of crude extracts: Validation and proof-of-concept study with Staphylococcus aureus

    Ardalani, H., Anam, S., Kromphardt, K. J. K., Stærk, Dan & Kongstad, K. T., 2021, In: Molecules. 26, 6, 12 p., 1550.

    Research output: Contribution to journalJournal articleResearchpeer-review

  227. Published

    Covalent inhibition of botulinum neurotoxin A: Exploration of warhead reactivity and function using a bifunctional approach

    Turner, L. D., Nielsen, A. L., Lin, L., Pellett, S., Sugane, T., Olson, M. E. & Janda, K. D., 2021, In: Toxicon. 190, Suppl. 1, p. S72-S73

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  228. Published

    Crosslinking glutamate receptor ion channels

    Plested, A. J. R. & Poulsen, Mette Homann, 2021, Methods in Enzymology. Elsevier, p. 161-192 30 p. (Methods in Enzymology, Vol. 652).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  229. Published

    Deconstructing Noncovalent Kelch-like ECH-Associated Protein 1 (Keap1) Inhibitors into Fragments to Reconstruct New Potent Compounds

    Pallesen, J. S., Narayanan, Dilip, Tran, K. T., Solbak, Sara Marie Øie, Marseglia, G., Sørensen, L. M. E., Høj, L. J., Munafò, F., Carmona, R. M. C., Garcia, A. D., Desu, H. L., Brambilla, R., Johansen, Tommy Nørskov, Popowicz, G. M., Sattler, M., Gajhede, Michael & Bach, Anders, 2021, In: Journal of Medicinal Chemistry. 64, 8, p. 4623–4661

    Research output: Contribution to journalJournal articleResearchpeer-review

  230. Published

    Deficient astrocyte metabolism impairs glutamine synthesis and neurotransmitter homeostasis in a mouse model of Alzheimer's disease

    Andersen, Jens Velde, Christensen, S. K., Westi, E. W., Diaz del Castillo, Marta, Tanila, H., Schousboe, Arne, Aldana, Blanca & Waagepetersen, H. S., 2021, In: Neurobiology of Disease. 148, 13 p., 105198.

    Research output: Contribution to journalJournal articleResearchpeer-review

  231. Published

    Delineation of the functional properties exhibited by the Zinc-Activated Channel (ZAC) and its high-frequency Thr128Ala variant (rs2257020) in Xenopus oocytes

    Madjroh, Nawid, Davies, P. A., Smalley, J. L., Kristiansen, Uffe, Söderhielm, P. C. & Jensen, Anders A., 2021, In: Pharmacological Research. 169, 18 p., 105653.

    Research output: Contribution to journalJournal articleResearchpeer-review

  232. Published

    Desorption Electrospray Ionization Mass Spectrometry Imaging of Cimbi-36, a 5-HT2A Receptor Agonist, with Direct Comparison to Autoradiography and Positron Emission Tomography

    Jacobsen, S. C., Speth, N. R., Xiong, M., Herth, Matthias Manfred, Kristensen, Jesper Langgaard, Palner, M. & Janfelt, Christian, 2021, In: Molecular Imaging and Biology. 23, p. 676–685

    Research output: Contribution to journalJournal articleResearchpeer-review

  233. Published

    Detecting deviations from the efficacy and safety results of single-arm trials using real-world data: The case of a CAR-T cell therapy in B-cell lymphoma

    Jakobsen, L. H., Callréus, T., Sessa, Maurizio, Jerkeman, M., Andersen, Morten & El-Galaly, T. C., 2021, In: Pharmacoepidemiology and Drug Safety. 30, 4, p. 514-519

    Research output: Contribution to journalJournal articleResearchpeer-review

  234. Published

    Determinants for α4β2 vs. α3β4 subtype selectivity of pyrrolidine-based nachrs ligands: A computational perspective with focus on recent cryo-em receptor structures

    Bavo, Francesco, Pallavicini, M., Appiani, R. & Bolchi, C., 2021, In: Molecules. 26, 12, 23 p., 3603.

    Research output: Contribution to journalJournal articleResearchpeer-review

  235. Published

    Development of Peptide-Based PDZ Domain Inhibitors

    Essig, D. J., Balboa, J. R. & Strømgaard, Kristian, 2021, Methods in Molecular Biology. J-P. B. (ed.). Humana Press, p. 157-177 21 p. (Methods in Molecular Biology, Vol. 2256).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  236. Published

    Development of Thiochroman Dioxide Analogues of Benzothiadiazine Dioxides as New Positive Allosteric Modulators of α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptors

    Etsè, K. S., Dorosz, J., McLain Christensen, K., Thomas, J. Y., Botez Pop, I., Goffin, E., Colson, T., Lestage, P., Danober, L., Pirotte, B., Kastrup, Jette Sandholm Jensen & Francotte, P., 2021, In: ACS Chemical Neuroscience. 12, 14, p. 2679-2692

    Research output: Contribution to journalJournal articleResearchpeer-review

  237. Published

    Development of the First Aliphatic 18F-Labeled Tetrazine Suitable for Pretargeted PET Imaging-Expanding the Bioorthogonal Tool Box

    Battisti, Umberto Maria, Bratteby, K., Jørgensen, Jesper Tranekjær, Hvass, Lars, Shalgunov, Vladimir, Mikula, H., Kjær, Andreas & Herth, Matthias Manfred, 2021, In: Journal of Medicinal Chemistry. 64, 20, p. 15297–15312

    Research output: Contribution to journalJournal articleResearchpeer-review

  238. Published

    Developmental Effects of Nicotine on Cognitive, Motivated and Executive Behaviors

    Kohlmeier, Kristi Anne & de Souza Polli, F., 2021, Diagnosis, Management and Modeling of Neurodevelopmental Disorders : The Neuroscience of Development. Martin, C. R., Rajendram, R. & Preedy, V. R. (eds.). Elsevier, p. 173-183

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  239. Published

    Direct Cu-mediated aromatic18F-labeling of highly reactive tetrazines for pretargeted bioorthogonal PET imaging

    García Vázquez, Rocío, Battisti, Umberto Maria, Jørgensen, Jesper Tranekjær, Shalgunov, Vladimir, Hvass, Lars, Stares, D. L., Petersen, I. N., Crestey, F., Löffler, A., Svatunek, D., Kristensen, Jesper Langgaard, Mikula, H., Kjær, Andreas & Herth, Matthias Manfred, 2021, In: Chemical Science. 12, 35, p. 11668-11675

    Research output: Contribution to journalJournal articleResearchpeer-review

  240. Published

    Discovery and functional characterization of N-(thiazol-2-yl)-benzamide analogs as the first class of selective antagonists of the Zinc-Activated Channel (ZAC)

    Madjroh, Nawid, Mellou, E., Davies, P. A., Söderhielm, P. C. & Jensen, Anders A., 2021, In: Biochemical Pharmacology. 193, 16 p., 114782.

    Research output: Contribution to journalJournal articleResearchpeer-review

  241. Published

    Discovery of GPR183 Agonists Based on an Antagonist Scaffold

    Kjær, V. M. S., Ieremias, L., Daugvilaite, V., Lückmann, Michael, Frimurer, Thomas Michael, Ulven, Trond, Rosenkilde, Mette & Våbenø, J., 2021, In: ChemMedChem. 16, 17, p. 2623-2627

    Research output: Contribution to journalJournal articleResearchpeer-review

  242. Published

    Downregulation of GABA Transporter 3 (GAT3) is Associated with Deficient Oxidative GABA Metabolism in Human Induced Pluripotent Stem Cell-Derived Astrocytes in Alzheimer's Disease

    Salcedo, C., Wagner, A., Andersen, Jens Velde, Vinten, K. T., Waagepetersen, H. S., Schousboe, Arne, Freude, Kristine & Aldana, Blanca, 2021, In: Neurochemical Research. 46, p. 2676–2686

    Research output: Contribution to journalJournal articleResearchpeer-review

  243. Published

    Drug poisoning in nursing homes: a retrospective study of data from the Danish Poison Information Centre

    Jakobsen, H. N., Vermehren, Charlotte, Andersen, Jon Thor Trærup & Dalhoff, Kim, 2021, In: Drugs and Therapy Perspectives. 37, 7, p. 328-337 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  244. Published

    Drugs That Changed Society: History and Current Status of the Early Antibiotics: Salvarsan, Sulfonamides, and β-Lactams

    Christensen, Søren Brøgger, 2021, In: Molecules. 26, 19, 31 p., 6057.

    Research output: Contribution to journalReviewResearchpeer-review

  245. Published

    Dual high-resolution α-glucosidase and PTP1B profiling combined with HPLC-PDA-HRMS-SPE-NMR analysis for the identification of potentially antidiabetic chromene meroterpenoids in Rhododendron capitatum

    Liang, C., Kjaerulff, Louise, Hansen, Paul Robert, Kongstad, K. T. & Stærk, Dan, 2021, In: Journal of Natural Products. 84, p. 2454-2467

    Research output: Contribution to journalJournal articleResearchpeer-review

  246. Published

    Dysphagia prevalence, time course, and association with probable sarcopenia, inactivity, malnutrition, and disease status in older patients admitted to an emergency department: A secondary analysis of cohort study data

    Hansen, T., Nielsen, R. L., Houlind, M. B., Tavenier, J., Rasmussen, L. J. H., Jørgensen, Lillian Mørch, Treldal, C., Beck, A. M., Pedersen, Mette Merete, Andersen, Ove, Petersen, Janne & Andersen, A. L., 2021, In: Geriatrics. 6, 2, 46.

    Research output: Contribution to journalJournal articleResearchpeer-review

  247. Published

    Early indicators of primary brain tumours: a population-based study with 10 years' follow-up

    Marku, M., Rasmussen, B. K., Dalton, Susanne Oksbjerg, Johansen, Christoffer, Hamerlík, Petra, Andersen, K. K., Meier, S. M. & Bidstrup, Pernille Envold Hansen, 2021, In: European Journal of Neurology. 28, 1, p. 278-285

    Research output: Contribution to journalJournal articleResearchpeer-review

  248. Published

    Effect of Increased Potassium Intake on Adrenal Cortical and Cardiovascular Responses to Angiotensin II: A Randomized Crossover Study

    Dreier, R., Andersen, U. B., Forman, Julie Lyng, Sheykhzade, Majid, Egfjord, Martin & Jeppesen, J. L., 2021, In: Journal of the American Heart Association. 10, 15 p., e018716.

    Research output: Contribution to journalJournal articleResearchpeer-review

  249. Published

    Effect of Roux-en-Y gastric bypass on the pharmacokinetic-pharmacodynamic relationships of liquid and controlled-release formulations of oxycodone

    Ladebo, L., Abuhelwa, A. Y., Foster, D. J. R., Kroustrup, J. P., Pacyk, G. J., Kongstad, K. T., Drewes, A. M., Christrup, Lona Louring & Olesen, A. E., 2021, In: Basic and Clinical Pharmacology and Toxicology. 129, 3, p. 232-245

    Research output: Contribution to journalJournal articleResearchpeer-review

  250. Published

    Effect of increased potassium intake on the renin-angiotensin-aldosterone system and subcutaneous resistance arteries: a randomized crossover study

    Dreier, R., Abdolalizadeh, B., Asferg, C. L., Hølmich, Lisbet Rosenkrantz, Buus, N. H., Forman, Julie Lyng, Andersen, U. B., Egfjord, Martin, Sheykhzade, Majid & Jeppesen, J. L., 2021, In: Nephrology, Dialysis, Transplantation. 36, 7, p. 1282–1291 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  251. Published

    Effects of charge contrast and composition on microgel formation and interactions with bacteria-mimicking liposomes

    Borro, B. C., Toussaint, M. S., Bucciarelli, S. & Malmsten, Martin, 2021, In: Biochimica et Biophysica Acta - General Subjects. 1865, 4, 9 p., 129485.

    Research output: Contribution to journalJournal articleResearchpeer-review

  252. Published

    Effects of delayed-release olive oil and hydrolyzed pine nut oil on glucose tolerance, incretin secretion and appetite in humans

    Sørensen, K. V., Kaspersen, M. H., Ekberg, J. H., Bauer-Brandl, A., Ulven, Trond & Højlund, K., 2021, In: Nutrients. 13, 10, 13 p., 3407.

    Research output: Contribution to journalJournal articleResearchpeer-review

  253. Published

    Electrophysiological and inflammatory changes of CA1 area in male rats exposed to acute kidney injury: Neuroprotective effects of erythropoietin

    Tahamtan, M., Kohlmeier, Kristi Anne, Faatehi, M., Basiri, M. & Shabani, M., 2021, In: Brain Research Bulletin. 171, p. 25-34

    Research output: Contribution to journalJournal articleResearchpeer-review

  254. Published

    Enhanced Physiological Stress Response in Patients with Normal Tension Glaucoma during Hypoxia

    Dalgaard, L. M., Vibæk, J., Vohra, Rupali, Jensen, Lars Thorbjørn, Cvenkel, B., Secher, Niels H., Olsen, N. V. & Kolko, Miriam, 2021, In: Journal of Ophthalmology. 2021, 5826361.

    Research output: Contribution to journalJournal articleResearchpeer-review

  255. Published

    Erythrina Alkaloid Analogues as nAChR Antagonists-A Flexible Platform for Leads in Drug Discovery

    Clementson, S., Matheu, S. A., Marcher, Emil, Pedersen, H., Jensen, Anders A., Clausen, Rasmus Prætorius, Vital, P., Glibstrup, E., Jessing, M. & Kristensen, Jesper Langgaard, 2021, In: The Journal of Organic Chemistry. 86, 12, p. 8248-8262

    Research output: Contribution to journalJournal articleResearchpeer-review

  256. Published

    Estrogen attenuates physical and psychological stress-induced cognitive impairments in ovariectomized rats

    Khaleghi, M., Rajizadeh, M. A., Bashiri, H., Kohlmeier, Kristi Anne, Mohammadi, F., Khaksari, M. & Shabani, M., 2021, In: Brain and Behavior. 11, 5, 15 p., e02139.

    Research output: Contribution to journalJournal articleResearchpeer-review

  257. Published

    Evaluation of 1H-Triazole-1-[N,N'-Bis(tert-butoxycarbonyl)]carboxamidine in Solution-Phase and On-Resin Guanidinylation

    Wester, Anita, Björkling, F. & Franzyk, Henrik, 2021, In: The Journal of Organic Chemistry. 86, 21, p. 14371–14380

    Research output: Contribution to journalJournal articleResearchpeer-review

  258. Published
  259. Published

    Evaluation of topical morphine for treatment of oral mucositis in cancer patients

    Nielsen, B. N., Friis, S. M., Schmiegelow, Kjeld, Henneberg, S. & Rømsing, Janne, 2021, In: British Journal of Pain. 15, 4, p. 409–417

    Research output: Contribution to journalJournal articleResearchpeer-review

  260. Published

    Facilitation of GluN2C-containing NMDA receptors in the external globus pallidus increases firing of fast spiking neurons and improves motor function in a hemiparkinsonian mouse model

    Liu, J., Shelkar, G. P., Sarode, L. P., Gawande, D. Y., Zhao, F., Clausen, Rasmus Prætorius, Ugale, R. R. & Dravid, S. M., 2021, In: Neurobiology of Disease. 150, 10 p., 105254.

    Research output: Contribution to journalJournal articleResearchpeer-review

  261. Published

    From Plant to Patient: Thapsigargin, a Tool for Understanding Natural Product Chemistry, Total Syntheses, Biosynthesis, Taxonomy, ATPases, Cell Death, and Drug Development

    Christensen, Søren Brøgger, Simonsen, H. T., Engedal, N., Nissen, P., Møller, J. V., Denmeade, S. R. & Isaacs, J. T., 2021, In: Progress in the chemistry of organic natural products. 115, p. 59-114

    Research output: Contribution to journalReviewResearchpeer-review

  262. Published

    Fully Automated GMP-Compliant Synthesis of [18F]FE-PE2I

    Bratteby, K., Denholt, Charlotte Lund, Lehel, S., Petersen, I. N., Madsen, J., Erlandsson, M., Ohlsson, T., Herth, Matthias Manfred & Gillings, N., 2021, In: Pharmaceuticals. 14, 7, 17 p., 601.

    Research output: Contribution to journalJournal articleResearchpeer-review

  263. Published

    Functional Characterization of Disease-Causing Mutations in the Sodium Leak Channel NALCN

    Weidling, Claudia, Ameen, A. O., Chua, Han Chow & Pless, Stephan, 2021, p. 10A-11A.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  264. Published

    Functional Metabolic Mapping Reveals Highly Active Branched-Chain Amino Acid Metabolism in Human Astrocytes, Which Is Impaired in iPSC-Derived Astrocytes in Alzheimer's Disease

    Salcedo, C., Andersen, Jens Velde, Vinten, K. T., Pinborg, Lars Hageman, Waagepetersen, H. S., Freude, Kristine & Aldana, Blanca, 2021, In: Frontiers in Aging Neuroscience. 13, 736580.

    Research output: Contribution to journalJournal articleResearchpeer-review

  265. Published

    Functional cross-talk between phosphorylation and disease-causing mutations in the cardiac sodium channel Nav1.5

    Galleano, Iacopo, Harms, Hendrik, Choudhury, K., Khoo, K., Delemotte, L. & Pless, Stephan, 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 33, 10 p., e2025320118.

    Research output: Contribution to journalJournal articleResearchpeer-review

  266. Published

    Functional proteomic profiling of triple-negative breast cancer

    Gromova, I., Espinoza, J. A., Grauslund, M., Santoni Rugiu, Eric, Talman, M. L. M., van Oostrum, J. & Moreira, José, 2021, In: Cells. 10, 10, 14 p., 2768.

    Research output: Contribution to journalJournal articleResearchpeer-review

  267. Published

    Furolabdane diterpenoids from Pseudodictamnus aucheri (Boiss.) Salmaki & Siadati (Lamiaceae) as chemophenetic markers

    Sadani, S., Sarrafi, Y. & Stærk, Dan, 2021, In: Biochemical Systematics and Ecology. 98, 4 p., 104304.

    Research output: Contribution to journalJournal articleResearchpeer-review

  268. Published

    G protein-coupled receptor modulators and a pharmaceutical composition

    Ulven, Trond & Ieremias, L., 2021, IPC No. A61K31/44, A61P25/00, A61P29/00, C07D213/69, C07D405/12, Patent No. WO 2021/123394 A1, 18 Dec 2020, Priority date 20 Dec 2019, Priority No. EP20150090A

    Research output: Patent

  269. Published

    G-protein activation by a metabotropic glutamate receptor

    Seven, A. B., Barros-Álvarez, X., de Lapeyrière, M., Papasergi-Scott, M. M., Robertson, M. J., Zhang, C., Nwokonko, R. M., Gao, Y., Meyerowitz, J. G., Rocher, J. P., Schelshorn, D., Kobilka, B. K., Mathiesen, Jesper M. & Skiniotis, G., 2021, In: Nature. 595, p. 450-454

    Research output: Contribution to journalJournal articleResearchpeer-review

  270. Published

    GABAA receptor β1-subunit knock-out mice show increased delta power in NREM sleep and decreased theta power in REM sleep

    Lie, M. E. K., Falk-Petersen, C. B., Petersen, Louise Piilgaard, Griem-Krey, Nane, Wellendorph, Petrine & Kornum, Birgitte Rahbek, 2021, In: European Journal of Neuroscience. 54, 2, p. 4445-4455 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  271. Published

    GHB analogs confer neuroprotection through specific interaction with the CaMKIIα hub domain

    Leurs, U., Klein, Anders Bue, McSpadden, E. D., Griem-Krey, Nane, Solbak, Sara Marie Øie, Houlton, J., Villumsen, I. S., Vogensen, S. B., Hamborg, L., Gauger, Stine Juul, Pedersen, Line Brogaard, Larsen, A. S. G., Shehata, Mohamed A., Kelstrup, C. D., Olsen, Jesper Velgaard, Bach, Anders, Burnie, R. O., Kerr, D. S., Gowing, E. K., Teurlings, S. M. W., Chi, C. C., Gee, C. L., Frølund, Bente, Kornum, Birgitte Rahbek, van Woerden, G. M., Clausen, Rasmus Prætorius, Kuriyan, J., Clarkson, A. N. & Wellendorph, Petrine, 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 31, 9 p., e2108079118.

    Research output: Contribution to journalJournal articleResearchpeer-review

  272. Published

    GLP-1 Val8: A Biased GLP-1R Agonist with Altered Binding Kinetics and Impaired Release of Pancreatic Hormones in Rats

    van der Velden, W. J. C., Smit, F. X., Christiansen, Charlotte Bayer, Møller, T. C., Hjortø, Gertrud Malene, Larsen, Olav, Schiellerup, S. P., Bräuner-Osborne, Hans, Holst, Jens Juul, Hartmann, Bolette, Frimurer, Thomas Michael & Rosenkilde, Mette, 2021, In: ACS Pharmacology & Translational Science. 4, 1, p. 296-313 18 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  273. Published

    GPCR activation mechanisms across classes and macro/microscales

    Hauser, Alexander Sebastian, Kooistra, Albert Jelke, Munk, C., Heydenreich, F. M., Veprintsev, D. B., Bouvier, M., Babu, M. M. & Gloriam, David E., 2021, In: Nature Structural and Molecular Biology. 28, 11, p. 879-888

    Research output: Contribution to journalJournal articleResearchpeer-review

  274. Published

    GPCRdb in 2021: integrating GPCR sequence, structure and function

    Kooistra, Albert Jelke, Mordalski, S., Pándy-Szekeres, G., Esguerra, M., Mamyrbekov, A., Munk, C., Keserű, G. M. & Gloriam, David E., 2021, In: Nucleic Acids Research. 49, D1, p. D335-D343

    Research output: Contribution to journalJournal articleResearchpeer-review

  275. Published

    Glaucoma Clinical Research: Trends in Treatment Strategies and Drug Development

    Storgaard, L., Tran, T. L., Freiberg, Josefine Clement, Hauser, Alexander Sebastian & Kolko, Miriam, 2021, In: Frontiers in Medicine. 8, 14 p., 733080.

    Research output: Contribution to journalReviewResearchpeer-review

  276. Published

    Glial Cells in Glaucoma: Friends, Foes, and Potential Therapeutic Targets

    Garcia Bermudez, Mariana Yolotzin, Freude, Kristine, Mouhammad, Zaynab Ahmad, van Wijngaarden, P., Martin, K. K. & Kolko, Miriam, 2021, In: Frontiers in Neurology. 12, 17 p., 624983.

    Research output: Contribution to journalReviewResearchpeer-review

  277. Published

    Glutamate Dehydrogenase Is Important for Ammonia Fixation and Amino Acid Homeostasis in Brain During Hyperammonemia

    Voss, C. M., Arildsen, L., Nissen, J. D., Waagepetersen, H. S., Schousboe, Arne, Maechler, P., Ott, P., Vilstrup, H. & Walls, Anne Byriel, 2021, In: Frontiers in Neuroscience. 15, 18 p., 646291.

    Research output: Contribution to journalJournal articleResearchpeer-review

  278. Published

    Glutamate metabolism and recycling at the excitatory synapse in health and neurodegeneration

    Andersen, Jens Velde, Markussen, K. H., Jakobsen, Emil, Schousboe, Arne, Waagepetersen, H. S., Rosenberg, P. A. & Aldana, Blanca, 2021, In: Neuropharmacology. 196, 14 p., 108719.

    Research output: Contribution to journalReviewResearchpeer-review

  279. Published

    HLA Class II Histocompatibility Antigen gamma Chain (CD74) Expression Is Associated with Immune Cell Infiltration and Favorable Outcome in Breast Cancer

    Noer, Julie Boertmann, Talman, M. M. & Moreira, José, 2021, In: Cancers. 13, 24, 16 p., 6179.

    Research output: Contribution to journalJournal articleResearchpeer-review

  280. Published

    Heparin promotes fibrillation of most phenol-soluble modulin virulence peptides from Staphylococcus aureus

    Najarzadeh, Z., Zaman, M., Sereikaité, Vita, Strømgaard, Kristian, Andreasen, M. & Otzen, D. E., 2021, In: Journal of Biological Chemistry. 297, 2, 14 p., 100953.

    Research output: Contribution to journalJournal articleResearchpeer-review

  281. Published

    High-throughput characterization of photocrosslinker-bearing ion channel variants to map residues critical for function and pharmacology

    Braun, Nina, Friis, S., Ihling, C., Sinz, A., Andersen, J. & Pless, Stephan, 2021, In: PLOS Biology. 19, 9, 30 p., e3001321.

    Research output: Contribution to journalJournal articleResearchpeer-review

  282. Published

    High-throughput screening of histone deacetylases and determination of kinetic parameters using fluorogenic assays

    Moreno Yruela, Carlos & Olsen, Christian Adam, 2021, In: STAR Protocols. 2, 1, 14 p., 100313.

    Research output: Contribution to journalJournal articleResearchpeer-review

  283. Published

    Hippocampal disruptions of synaptic and astrocyte metabolism are primary events of early amyloid pathology in the 5xFAD mouse model of Alzheimer's disease

    Andersen, Jens Velde, Skotte, N. H., Christensen, S. K., Polli, F. S., Shabani, M., Markussen, K. H., Haukedal, Henriette, Westi, E. W., Diaz del Castillo, Marta, Sun, R. C., Kohlmeier, Kristi Anne, Schousboe, Arne, Gentry, M. S., Tanila, H., Freude, Kristine, Aldana, Blanca, Mann, Matthias & Waagepetersen, H. S., 2021, In: Cell Death & Disease. 12, 11, 13 p., 954 .

    Research output: Contribution to journalJournal articleResearchpeer-review

  284. Published

    Human Fibrinogen Inhibits Amyloid Assembly of Most Phenol-Soluble Modulins from Staphylococcus aureus

    Najarzadeh, Z., Nielsen, J., Farzadfard, A., Sereikaité, Vita, Strømgaard, Kristian, Meyer, R. L. & Otzen, D. E., 2021, In: ACS Omega. 6, 34, p. 21960-21970

    Research output: Contribution to journalJournal articleResearchpeer-review

  285. Published

    IL-13 and IL-4 promote proliferation and mRNA expression of MUC2 and MUC5AC in primary human conjunctival goblet cells

    Tollenaere, M. A. X., Hansen, Pernille May, Hedengran, A., Heegaard, Steffen, Roepke, M., Norsgaard, H., Thyssen, Jacob Pontoppidan & Kolko, Miriam, 2021, In: Experimental Dermatology. 30, S2, p. 21-21

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  286. Published

    Identification of lysosome‐targeting drugs with anti‐inflammatory activity as potential invasion inhibitors of treatment resistant HER2 positive cancers

    Hansen, M. B., Postol, M., Tvingsholm, S., Nielsen, I. Ø., Dietrich, T. N., Puustinen, P., Maeda, K., Dinant, C., Strauss, R., Egan, D., Jaattela, Marja & Kallunki, Tuula Anneli, 2021, In: Cellular Oncology. 44, p. 805–820

    Research output: Contribution to journalJournal articleResearchpeer-review

  287. Published

    Identification of novel fragments binding to the PDZ1-2 domain of PSD-95

    Zang, Jie, Ye, F., Solbak, Sara Marie Øie, Høj, L. J., Zhang, M. & Bach, Anders, 2021, In: ChemMedChem. 16, 6, p. 949-954

    Research output: Contribution to journalJournal articleResearchpeer-review

  288. Published

    Identification of potent epitopes on hexon capsid protein and their evaluation as vaccine candidates against infections caused by members of Adenoviridae family

    Tufail, S., Shah, M. A., Zafar, M., Asif, T. A., Shehzad, A., Shah, M. S., Habib, M., Saleemi, M. K., Muddassar, M., Mirza, Osman Asghar, Iqbal, M. & Rahman, M., 2021, In: Vaccine. 39, 27, p. 3560-3564 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  289. Published

    Imaging Biomarkers for Monitoring the Inflammatory Redox Landscape in the Brain

    Alves Fernandes, Eduardo Felipe & Ozcelik, D., 2021, In: Antioxidants. 10, 4, 19 p., 528.

    Research output: Contribution to journalReviewResearchpeer-review

  290. Published

    Immune-to-Brain Signaling Effects on the Neural Substrate for Reward: Behavioral Models of Aversion, Anhedonia, and Despair

    Klawonn, Anna Mathia & Fritz, M., 2021, Neuromethods. Humana Press, p. 145-167 (Neuromethods, Vol. 165).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  291. Published

    Impact of benzalkonium chloride-preserved and preservative-free latanoprost eye drops on cultured human conjunctival goblet cells upon acute exposure and differences in physicochemical properties of the eye drops

    Mullertz, O., Hedengran, A., Mouhammad, Zaynab Ahmad, Freiberg, Josefine Clement, Nagymihaly, R., Jacobsen, Jette, Larsen, Susan Weng, Bair, J., Utheim, T., Dartt, D. A., Heegaard, Steffen, Petrovski, G. & Kolko, Miriam, 2021, In: BMJ Open Ophthalmology. 6, 1, 7 p., 000892.

    Research output: Contribution to journalJournal articleResearchpeer-review

  292. Published

    In vivo modulation of ubiquitin chains by N -methylated non-proteinogenic cyclic peptides

    Rogers, Joseph Matthew, Nawatha, M., Lemma, B., Vamisetti, G. B., Livneh, I., Barash, U., Vlodavsky, I., Ciechanover, A., Fushman, D., Suga, H. & Brik, A., 2021, In: RSC Chemical Biology. 2, 2, p. 513-522 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  293. Published

    Incident Atrial Fibrillation and Risk of Psychoactive Drug Redemptions and Psychiatric Hospital Contacts - a Danish Nationwide Register-based Follow-up Study

    Hagengaard, L., Polcwiartek, C., Andersen, M. P., Sessa, Maurizio, Krogager, M. L., Gislason, Gunnar Hilmar, Schou, Morten, Torp-Pedersen, C., Søgaard, P. & Kragholm, K. H., 2021, In: European Heart Journal - Quality of Care and Clinical Outcomes. 7, 1, p. 76-82

    Research output: Contribution to journalJournal articleResearchpeer-review

  294. Published

    Inflammation in Glaucoma: From the back to the front of the eye, and beyond

    Baudouin, C., Kolko, Miriam, Melik-Parsadaniantz, S. & Messmer, E. M., 2021, In: Progress in Retinal and Eye Research. 83, 100916.

    Research output: Contribution to journalReviewResearchpeer-review

  295. Published

    Inhibition of Glutamate Release, but Not of Glutamine Recycling to Glutamate, Is Involved in Delaying the Onset of Initial Lithium-Pilocarpine-Induced Seizures in Young Rats by a Non-Convulsive MSO Dose

    Pawlik, M. J., Aldana, Blanca, Belfiori-Carrasco, L. F., Obara-Michlewska, M., Popek, M. P., Czarnecka, A. M. & Albrecht, J., 2021, In: International Journal of Molecular Sciences. 22, 20, 16 p., 11127.

    Research output: Contribution to journalJournal articleResearchpeer-review

  296. Published

    Inoculum effect of antimicrobial peptides

    Loffredo, M. R., Savini, F., Bobone, S., Casciaro, B., Franzyk, Henrik, Mangoni, M. L. & Stella, L., 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 21, 10 p., e2014364118.

    Research output: Contribution to journalJournal articleResearchpeer-review

  297. Published
  298. Published

    Insight into Calcium-Binding Motifs of Intrinsically Disordered Proteins

    Newcombe, Estella Anne, Fernandes, Catarina, Lundsgaard, J. E., Brakti, Inna, Lindorff-Larsen, Kresten, Langkilde, Annette Eva, Skriver, Karen & Kragelund, Birthe Brandt, 2021, In: Biomolecules. 11, 8, 17 p., 1173.

    Research output: Contribution to journalJournal articleResearchpeer-review

  299. Published

    Insights into Elution of Anion Exchange Cartridges: Opening the Path toward Aliphatic 18F-Radiolabeling of Base-Sensitive Tracers

    Bratteby, K., Shalgunov, Vladimir, Battisti, Umberto Maria, Petersen, I. N., Lopes van den Broek, Sara Irene, Ohlsson, T., Gillings, N., Erlandsson, M. & Herth, Matthias Manfred, 2021, In: ACS Pharmacology and Translational Science. 4, 5, p. 1556–1566

    Research output: Contribution to journalJournal articleResearchpeer-review

  300. Published

    Interplay of Nav1.5 Disease-Causing Mutations and Phosphorylation Revealed by Protein Semi-Synthesis and Molecular Dynamics Simulations

    Galleano, Iacopo, Harms, Hendrik, Choudhury, K., Khoo, K. K., Delemotte, L. & Pless, Stephan, 2021, p. 288A-288A.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  301. Published

    Investigating the role of 5-HT2A and 5-HT2C receptor activation in the effects of psilocybin, DOI, and citalopram on marble burying in mice

    Odland, Anna Ulstein, Kristensen, Jesper Langgaard & Andreasen T., Jesper, 2021, In: Behavioural Brain Research. 401, 5 p., 113093.

    Research output: Contribution to journalJournal articleResearchpeer-review

  302. Published

    Ion channel engineering using protein trans-splicing

    Sarkar, Debayan, Harms, Hendrik, Galleano, Iacopo, Sheikh, Zeshan Pervez & Pless, Stephan, 2021, Methods in Enzymology. Elsevier, p. 19-48 30 p. (Methods in Enzymology).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  303. Published

    Irreversible inhibition of BoNT/A protease: proximity-driven reactivity contingent upon a bifunctional approach

    Turner, L. D., Nielsen, A. L., Lin, L., Pellett, S., Sugane, T., Olson, M. E., Johnson, E. A. & Janda, K. D., 2021, In: RSC Medicinal Chemistry. 12, 6, p. 960-969

    Research output: Contribution to journalJournal articleResearchpeer-review

  304. Published

    Is the Strongest Level of Medical Evidence Always Required for Guidelines Recommendations?

    Ravaioli, M., Piscaglia, F., Cillo, U., Brandi, G., Sessa, Maurizio, Germinario, G., Golfieri, R., Cappelli, A., Morelli, M. C., Siniscalchi, A., D'Errico, A., Cescon, M., Iannone, P. & Trevisani, F., 2021, In: Liver Cancer. 10, p. 394–395

    Research output: Contribution to journalLetterResearch

  305. Published

    Is the unique benzodiazepine structure interacting with CYP enzymes to affect steroid synthesis in vitro?

    Johannsen, M. L., Munkboel, C. H., Jørgensen, Flemming Steen & Styrishave, Bjarne, 2021, In: Journal of Steroid Biochemistry and Molecular Biology. 205, 10 p., 105765.

    Research output: Contribution to journalJournal articleResearchpeer-review

  306. Published
  307. Published

    Jagten på bioaktive naturstoffer: Sammenkoblet HPLC-PDA-HRMS-SPE-NMR til hurtig identifikation af bioaktive naturstoffer i komplekse blandinger

    Stærk, Dan, 2021, In: Dansk Kemi. 102, 4, p. 40-44

    Research output: Contribution to journalContribution to newspaper - Feature articleCommunication

  308. Published

    KLIFS: an overhaul after the first 5 years of supporting kinase research

    Kanev, G. K., de Graaf, C., Westerman, B. A., de Esch, I. J. P. & Kooistra, Albert Jelke, 2021, In: Nucleic Acids Research. 49, D1, p. D562-D569

    Research output: Contribution to journalJournal articleResearchpeer-review

  309. Published

    Lipid-bound ApoE3 self-assemble into elliptical disc-shaped particles

    Nørgrd Larsen, Andreas, Johansen, Nicolai Tidemand, Gajhede, Michael, Arleth, Lise & Midtgaard, S. R., 2021, In: B B A - Biomembranes. 1863, 1, 10 p., 183495.

    Research output: Contribution to journalJournal articleResearchpeer-review

  310. Published

    Lipophilicity and Click Reactivity Determine the Performance of Bioorthogonal Tetrazine Tools in Pretargeted In Vivo Chemistry

    Steen, E. J. L., Jørgensen, Jesper Tranekjær, Denk, C., Battisti, Umberto Maria, Norregaard, K., Edem, P. E., Bratteby, K., Shalgunov, Vladimir, Wilkovitsch, M., Svatunek, D., Poulie, Christian Bernard Matthijs, Hvass, Lars, Simon, M., Wanek, T., Rossin, R., Robillard, M., Kristensen, Jesper Langgaard, Mikula, H., Kjær, Andreas & Herth, Matthias Manfred, 2021, In: ACS Pharmacology & Translational Science. 4, 2, p. 824-833 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  311. Published

    Looking into a Deluded Brain through a Neuroimaging Lens

    Arjmand, S., Kohlmeier, Kristi Anne, Behzadi, M., Ilaghi, M., Mazhari, S. & Shabani, M., 2021, In: The Neuroscientist. 27, 1, p. 73-87

    Research output: Contribution to journalJournal articleResearchpeer-review

  312. Published

    Loss of Function Glucose-Dependent Insulinotropic Polypeptide Receptor Variants Are Associated With Alterations in BMI, Bone Strength and Cardiovascular Outcomes

    Kizilkaya, Hüsün Sheyma, Sørensen, Kimmie Vestergaard, Kibsgaard, C. J., Gasbjerg, Lærke Smidt, Hauser, Alexander Sebastian, Sparre-Ulrich, A. H., Grarup, Niels & Rosenkilde, Mette, 2021, In: Frontiers in Cell and Developmental Biology. 9, 12 p., 749607.

    Research output: Contribution to journalJournal articleResearchpeer-review

  313. Published

    Major bleeding in users of direct oral anticoagulants in atrial fibrillation: A pooled analysis of results from multiple population-based cohort studies

    van den Ham, H. A., Souverein, P. C., Klungel, O. H., Platt, R. W., Ernst, P., Dell'Aniello, S., Schmiedl, S., Grave, B., Rottenkolber, M., Huerta, C., Martin Merino, E., Leon-Munoz, L. M., Montero, D., Andersen, Morten, Aakjær, Mia, De Bruin, M. L. & Gardarsdottir, H., 2021, In: Pharmacoepidemiology and Drug Safety. 30, 10, p. 1339-1352

    Research output: Contribution to journalJournal articleResearchpeer-review

  314. Published

    Male Fertility Before and After Androgen Abuse

    Windfeld-Mathiasen, J., Dalhoff, Kim, Andersen, Jon Thor Trærup, Klemp, Marc Patrick Brag, Horwitz, Anna & Horwitz, Henrik, 2021, In: The Journal of clinical endocrinology and metabolism. 106, 2, p. 442-449 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  315. Published

    Markov state models of proton- and pore-dependent activation in a pentameric ligand-gated ion channel

    Bergh, C., Heusser, Stephanie, Howard, R. & Lindahl, E., 2021, In: eLife. 10, 23 p., 68369.

    Research output: Contribution to journalJournal articleResearchpeer-review

  316. Published

    Mechanism-based inhibitors of SIRT2: structure–activity relationship, X-ray structures, target engagement, regulation of α-tubulin acetylation and inhibition of breast cancer cell migration

    Nielsen, A. L., Rajabi, N., Kudo, N., Larsen, Kathrine Lundø, Moreno Yruela, Carlos, Bæk, M., Fontenas, M., Lucidi, A., Madsen, A. S., Yoshida, M. & Olsen, Christian Adam, 2021, In: RSC Chemical Biology. 2, p. 612-626

    Research output: Contribution to journalJournal articleResearchpeer-review

  317. Published

    Mipsagargin: The Beginning—Not the End—of Thapsigargin Prodrug-Based Cancer Therapeutics

    Isaacs, J. T., Brennen, W. N., Christensen, Søren Brøgger & Denmeade, S. R., 2021, In: Molecules. 26, 24, 7469.

    Research output: Contribution to journalReviewResearchpeer-review

  318. Published

    Mitochondria-targeted inhibitors of the human SIRT3 lysine deacetylase

    Troelsen, K. S., Bæk, M., Nielsen, A. L., Madsen, A. S., Rajabi, N. & Olsen, Christian Adam, 2021, In: RSC Chemical Biology. 2, p. 627-635

    Research output: Contribution to journalJournal articleResearchpeer-review

  319. Published

    Molecular Details of a Coupled Binding and Folding Reaction between the Amyloid Precursor Protein and a Folded Domain

    Jensen, T. M. T., Bartling, Christian Reinhard Otto, Karlsson, O. A., Åberg, E., Haugaard-Kedström, L. M., Strømgaard, Kristian & Jemth, P., 2021, In: ACS chemical biology. 16, 7, p. 1191-1200

    Research output: Contribution to journalJournal articleResearchpeer-review

  320. Published

    Molecular Determinants and Pharmacological Analysis for a Class of Competitive Non-transported Bicyclic Inhibitors of the Betaine/GABA Transporter BGT1

    Kickinger, Stefanie, Lie, M. E. K., Suemasa, A., Al-Khawaja, A., Fujiwara, K., Watanabe, M., Wilhelmsen, K. S., Falk-Petersen, C. B., Frølund, Bente, Shuto, S., Ecker, G. F. & Wellendorph, Petrine, 2021, In: Frontiers in Chemistry. 9, 13 p., 736457.

    Research output: Contribution to journalJournal articleResearchpeer-review

  321. Published

    Molecular Determinants underlying Delta Selective Compound 2 (DS2) Activity at δ-Containing GABAA Receptors

    Falk-Petersen, C. B., Rostrup, F., Löffler, R., Buchleihtner, S., Harpsøe, Kasper, Gloriam, David E., Frølund, Bente & Wellendorph, Petrine, 2021, In: Molecular Pharmacology. 100, 1, p. 46-56

    Research output: Contribution to journalJournal articleResearchpeer-review

  322. Published
  323. Published

    Multiple myeloma—A painful disease of the bone marrow

    Diaz del Castillo, Marta, Chantry, A. D., Lawson, M. A. & Heegaard, Anne-Marie, 2021, In: Seminars in Cell and Developmental Biology. 112, p. 49-58

    Research output: Contribution to journalJournal articleResearchpeer-review

  324. Published

    Multisite NHERF1 phosphorylation controls GRK6A regulation of hormone-sensitive phosphate transport

    Vistrup-Parry, Maria, Sneddon, W. B., Bach, S., Strømgaard, Kristian, Friedman, P. A. & Mamonova, T., 2021, In: Journal of Biological Chemistry. 296, 12 p., 100473.

    Research output: Contribution to journalJournal articleResearchpeer-review

  325. Published

    Mutational Diversity in the Quinolone Resistance-Determining Regions of Type-II Topoisomerases of Salmonella Serovars

    Shaheen, A., Tariq, A., Iqbal, M., Mirza, Osman Asghar, Haque, A., Walz, T. & Rahman, M., 2021, In: Antibiotics. 10, 12, 26 p., 1455.

    Research output: Contribution to journalJournal articleResearchpeer-review

  326. Published

    Mutational Landscape of the Proglucagon-Derived Peptides

    Lindquist, P., Madsen, J. S., Bräuner-Osborne, Hans, Rosenkilde, Mette & Hauser, Alexander Sebastian, 2021, In: Frontiers in Endocrinology. 12, 14 p., 698511.

    Research output: Contribution to journalJournal articleResearchpeer-review

  327. Published

    Natural Products that Changed Society

    Christensen, Søren Brøgger, 2021, In: Biomedicines. 9, 5, 31 p., 472.

    Research output: Contribution to journalReviewResearchpeer-review

  328. Published

    Navigating through chemical space and evolutionary time across the Australian continent in plant genus Eremophila

    Gericke, Oliver, Fowler, R., Heskes, A., Bayly, M., Semple, S., Ndi, C. P., Stærk, Dan, Loland, Claus Juul, Murphy, D. J., Buirchell, B. & Møller, Birger Lindberg, 2021, In: Plant Journal. 108, 2, p. 555-578

    Research output: Contribution to journalJournal articleResearchpeer-review

  329. Published

    Neural Derivates of Canine Induced Pluripotent Stem Cells-Like Cells From a Mild Cognitive Impairment Dog

    Chandrasekaran, Abinaya, Thomsen, B. B., Agerholm, Jørgen Steen, Pessôa, L. V. D. F., Godoy Pieri, N. C., Sabaghidarmiyan, V., Langley, K., Kolko, Miriam, De Andrade, A. F. C., Bressan, F. F., Hyttel, P., Berendt, Mette & Freude, Kristine, 2021, In: Frontiers in Veterinary Science. 8, 14 p., 725386.

    Research output: Contribution to journalJournal articleResearchpeer-review

  330. Published

    Neurokinins and their receptors in the rat trigeminal system: Differential localization and release with implications for migraine pain

    Edvinsson, Jacob Carl Alexander, Reducha, Philip Victor, Sheykhzade, Majid, Warfvinge, K., Haanes, Kristian Agmund & Edvinsson, L., 2021, In: Molecular Pain. 17, p. 1-11

    Research output: Contribution to journalJournal articleResearchpeer-review

  331. Published

    Neuronal Loss of the Glutamate Transporter GLT-1 Promotes Excitotoxic Injury in the Hippocampus

    Rimmele, T. S., Li, S., Andersen, Jens Velde, Westi, E. W., Rotenberg, A., Wang, J., Aldana, Blanca, Selkoe, D. J., Aoki, C. J., Dulla, C. G. & Rosenberg, P. A., 2021, In: Frontiers in Cellular Neuroscience. 15, 788262.

    Research output: Contribution to journalJournal articleResearchpeer-review

  332. Published

    Neuroprotection Against NMDA-Induced Retinal Damage by Philanthotoxin-343 Involves Reduced Nitrosative Stress

    Mohamad, M. H. N., Abu, I. F., Fazel, M. F., Agarwal, R., Iezhitsa, I., Juliana, N., Mellor, I. R. & Franzyk, Henrik, 2021, In: Frontiers in Pharmacology. 12, 11 p., 798794.

    Research output: Contribution to journalJournal articleResearchpeer-review

  333. Published
  334. Published

    New use for old drugs: Epirubicin in colorectal cancer

    Tarpgaard, L. S., Qvortrup, C., Nielsen, S. L., Stenvang, Jan, Detlefsen, S., Brünner, Nils & Pfeiffer, P., 2021, In: Acta Oncologica. 60, 7, p. 954-956 3 p.

    Research output: Contribution to journalLetterResearchpeer-review

  335. Published

    Nicotinamide provides neuroprotection in glaucoma by protecting against mitochondrial and metabolic dysfunction

    Tribble, J. R., Otmani, A., Sun, S., Ellis, S. A., Cimaglia, G., Vohra, Rupali, Jöe, M., Lardner, E., Venkataraman, A. P., Domínguez-Vicent, A., Kokkali, E., Rho, S., Jóhannesson, G., Burgess, R. W., Fuerst, P. G., Brautaset, R., Kolko, Miriam, Morgan, J. E., Crowston, J. G., Votruba, M. & Williams, P. A., 2021, In: Redox Biology. 43, 21 p., 101988.

    Research output: Contribution to journalJournal articleResearchpeer-review

  336. Published

    Novel Approaches to Optimize Treatment Strategies in Glaucoma

    Kolko, Miriam, Heegaard, Steffen & Cvenkel, B., 2021, In: Journal of Ophthalmology. 2021, 9876478.

    Research output: Contribution to journalEditorialResearchpeer-review

  337. Published

    On the consensus nomenclature rules for radiopharmaceutical chemistry - Reconsideration of radiochemical conversion

    Herth, Matthias Manfred, Ametamey, S., Antuganov, D., Bauman, A., Berndt, M., Brooks, A. F., Bormans, G., Choe, Y. S., Gillings, N., Hafeli, U. O., James, M. L., Kopka, K., Kramer, V., Krasikova, R., Madsen, J., Mu, L., Neumaier, B., Piel, M., Roesch, F., Ross, T., Schibli, R., Scott, P. J. H., Shalgunov, Vladimir, Vasdev, N., Wadsak, W. & Zeglis, B. M., 2021, In: Nuclear Medicine and Biology. 93, p. 19-21 3 p.

    Research output: Contribution to journalEditorialResearchpeer-review

  338. Published

    One-Pot Synthesis of Xanthone by Carbonylative Suzuki Coupling Reaction

    Loureiro, D. R. P., Soares, J. X., Maia, A., Silva, A. M. N., Rangel, M., Azevedo, C. M. G., Hansen, S., Ulven, Trond, Pinto, M. M. M., Reis, S. & Afonso, C. M. M., 2021, In: ChemistrySelect. 6, 18, p. 4511-4514 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  339. Published

    Opioid Specific Effects on Central Processing of Sensation and Pain: A Randomized, Cross-Over, Placebo-Controlled Study

    Lelic, D., Olesen, A. E., Grønlund, D., Jure, F. A. & Drewes, A. M., 2021, In: Journal of Pain. 22, 11, p. 1477-1496

    Research output: Contribution to journalJournal articleResearchpeer-review

  340. Published

    Optimization of Nutrition And Medication (OptiNAM) for acutely admitted older patients: protocol for a randomized single-blinded controlled trial

    Andersen, A. L., Houlind, M. B., Nielsen, R. L., Jørgensen, Lillian Mørch, Treldal, C., Damgaard, Morten, Bengaard, A. K., Juul-Larsen, H. G., Laursen, L. B., Iversen, E., Kruse, M., Pedersen, Anne Marie Lynge, Hornum, M., Beck, A. M., Pedersen, Mette Merete, Ankarfeldt, Mikkel Zöllner, Petersen, Janne & Andersen, Ove, 2021, In: Trials. 22, 616, 20 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  341. Published

    Optimized Synthesis of Fmoc/Boc-Protected PNA Monomers and their Assembly into PNA Oligomers.

    Shaikh, Ashif Yasin, Björkling, F., Nielsen, Peter E. & Franzyk, Henrik, 2021, In: European Journal of Organic Chemistry. 2021, 19, p. 2792-2801 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  342. Published

    Oral absorption of oxycodone in patients with short bowel syndrome

    Ladebo, L., Vinter-Jensen, L., Hestvang, J., Mikkelsen, M. S., Rasmussen, H. H., Christrup, Lona Louring, Drewes, A. M. & Olesen, A. E., 2021, In: Scandinavian Journal of Gastroenterology. 56, 9, p. 1023-1029

    Research output: Contribution to journalJournal articleResearchpeer-review

  343. Published

    Organic osmolytes increase expression of specific tight junction proteins in skin and alter barrier function in keratinocytes

    El-Chami, C., Foster, A. R., Johnson, C., Clausen, Rasmus Prætorius, Cornwell, P., Haslam, I. S., Steward, M. C., Watson, R. E. B., Young, H. S. & O'Neill, C. A., 2021, In: British Journal of Dermatology. 184, 3, p. 482-494

    Research output: Contribution to journalJournal articleResearchpeer-review

  344. Published

    Oxidative stress in optic neuropathies

    Sanz-Morello, B., Ahmadi, H., Vohra, Rupali, Saruhanian, Sarkis, Freude, Kristine, Hamann, Steffen & Kolko, Miriam, 2021, In: Antioxidants. 10, 10, 27 p., 1538.

    Research output: Contribution to journalReviewResearchpeer-review

  345. Published

    PTR2/POT/NPF transporters: what makes them tick?

    Prabhala, B. K., Rahman, M., Nour-Eldin, Hussam Hassan, Jørgensen, Flemming Steen & Mirza, Osman Asghar, 2021, In: Advances in Protein Chemistry and Structural Biology. 123, p. 219-240 22 p.

    Research output: Contribution to journalReviewResearchpeer-review

  346. Published

    Peptide inhibitors as tool compounds targeting GPCR signaling

    Daver, H., Harpsøe, Kasper & Gloriam, David E., 2021, In: European Biophysics Journal. 50, SUPPL 1, p. 161-161 238.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  347. Published

    Peptide/β-Peptoid Hybrids with Activity against Vancomycin-Resistant Enterococci: Influence of Hydrophobicity and Structural Features on Antibacterial and Hemolytic Properties

    Vestergaard, M., Skive, Bolette, Domraceva, I., Ingmer, Hanne & Franzyk, Henrik, 2021, In: International Journal of Molecular Sciences. 22, 11, 5617.

    Research output: Contribution to journalJournal articleResearchpeer-review

  348. Published

    Peptide/β-Peptoid Hybrids with Ultrashort PEG-Like Moieties: Effects on Hydrophobicity, Antibacterial Activity and Hemolytic Properties

    Frederiksen, Nicki, Louka, S., Mudaliar, C., Domraceva, I., Kreicberga, A., Pugovics, O., Żabicka, D., Tomczak, M., Wygoda, W., Björkling, F. & Franzyk, Henrik, 2021, In: International Journal of Molecular Sciences. 22, 13, 17 p., 7041.

    Research output: Contribution to journalJournal articleResearchpeer-review

  349. Published

    Perfluoro-tert-butanol for selective on-resin detritylation: a mild alternative to traditionally used methods

    Wester, Anita, Hansen, A. M., Hansen, Paul Robert & Franzyk, Henrik, 2021, In: Amino Acids. 53, p. 1455–1466

    Research output: Contribution to journalJournal articleResearchpeer-review

  350. Published

    Personalized Medicine Through GPCR Pharmacogenomics

    Hauser, Alexander Sebastian, 2021, Personalized Medicine Through GPCR Pharmacogenomics. Kenakin, T. (ed.). Elsevier, 29 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  351. Published

    Perspective: targeting VEGF-A and YKL-40 in glioblastoma–matter matters

    Holst, Camilla Bjørnbak, Pedersen, H., Obara, E. A. A., Vitting-Seerup, K., Jensen, K. E., Skjøth-Rasmussen, J., Lund, Eva Løbner, Poulsen, Hans Skovgaard, Johansen, Julia Sidenius & Hamerlík, Petra, 2021, In: Cell Cycle. 20, 7, p. 702-715

    Research output: Contribution to journalJournal articleResearchpeer-review

  352. Published

    Pharmacoepidemiological methods for computing the duration of pharmacological prescriptions using secondary data sources

    Meaidi, M., Støvring, H., Rostgaard, K., Torp-Pedersen, C., Kragholm, K. H., Andersen, Morten & Sessa, Maurizio, 2021, In: European Journal of Clinical Pharmacology. 77, p. 1805–1814

    Research output: Contribution to journalReviewResearchpeer-review

  353. Published

    Pharmacological and epidemiological considerations while constructing drug treatment episodes using observational data retrospectively collected: A simulation study

    Pazzagli, L., Andersen, Morten & Sessa, Maurizio, 2021, In: Pharmacoepidemiology and Drug Safety. 30, S1, p. 298-299

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  354. Published

    Pharmacological inhibition of mitochondrial soluble adenylyl cyclase in astrocytes causes activation of AMP-activated protein kinase and induces breakdown of glycogen

    Jakobsen, Emil, Andersen, Jens Velde, Christensen, S. K., Siamka, O., Larsen, M. R., Waagepetersen, H. S., Aldana, Blanca & Bak, Lasse Kristoffer, 2021, In: Glia. 69, 12, p. 2828-2844 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  355. Published

    Phytochemical investigation of Eremophila spp.

    Bredahl, E. K., Ergin, Y., Kjaerulff, Louise & Stærk, Dan, 2021, p. 1.

    Research output: Contribution to conferencePosterResearch

  356. Published

    Pirfenidone Is a Vasodilator: Involvement of KV7 Channels in the Effect on Endothelium-Dependent Vasodilatation in Type-2 Diabetic Mice

    Beck, L., Pinilla, E., Arcanjo, D. D. R., Hernanz, R., Prat-Duran, J., Petersen, A. G., Köhler, R., Sheykhzade, Majid, Comerma-Steffensen, S. & Simonsen, U., 2021, In: Frontiers in Pharmacology. 11, 19 p., 619152.

    Research output: Contribution to journalJournal articleResearchpeer-review

  357. Published

    Post-oral fat-induced satiation is mediated by endogenous CCK and GLP-1 in a fat self-administration mouse model

    Vana, Vasiliki, Lærke, M. K., Kleberg, K., Mroz, P. A., Lindberg, B. L., Ekberg, J. H., Rehfeld, Jens Frederik, Schwartz, Thue W. & Hansen, Harald S., 2021, In: Physiology and Behavior. 234, 12 p., 113315.

    Research output: Contribution to journalJournal articleResearchpeer-review

  358. Published

    Potential antidiabetic phytochemicals in plant roots: a review of in vivo studies

    Ardalani, H., Hejazi Amiri, F., Hadipanah, A. & Kongstad, K. T., 2021, In: Journal of Diabetes and Metabolic Disorders. 20, p. 1837–1854

    Research output: Contribution to journalReviewResearchpeer-review

  359. Published

    Preface for the Vladimir Parpura Honorary Issue of Neurochemical Research

    Verkhratsky, A., Schousboe, Arne & Zorec, R., 2021, In: Neurochemical Research. 46, 10, p. 2507-2511

    Research output: Contribution to journalEditorialResearch

  360. Published

    Prescribers' compliance with summary of product characteristics of dabigatran, rivaroxaban and apixaban—A European comparative drug utilization study

    Rottenkolber, M., Schmiedl, S., Ibáñez, L., Sabate, M., Ballarin, E., Vidal, X., Leon-Munoz, L. M., Huerta, C., Merino, E. M., Montero, D., Gasse, C., Andersen, Morten, Aakjær, Mia, De Bruin, M. L. (., Gerlach, R. G., Tauscher, M., Souverein, P. C., Van den Ham, R., Klungel, O. H. & Gardarsdottir, H., 2021, In: Basic & Clinical Pharmacology & Toxicology. 128, 3, p. 440-454

    Research output: Contribution to journalJournal articleResearchpeer-review

  361. Published

    Prevalence of Charles Bonnet syndrome in patients with glaucoma: a systematic review with meta-analyses

    Subhi, Y., Schmidt, D. C., Bach-Holm, Daniella, Kolko, Miriam & Singh, Amardeep, 2021, In: Acta Ophthalmologica. 99, 2, p. 128-133 6 p.

    Research output: Contribution to journalReviewResearchpeer-review

  362. Published

    Probing Allosteric Networks in Ligand-Gated Ion Channel Gating by Electrophysiology and Molecular Dynamics in the Model Receptor GLIC

    Howard, R. J., Zhuang, Y., Gutheim, S., Zeckey, L., Heusser, Stephanie & Lindahl, E. R., 2021, p. 58A-58A.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  363. Published

    Probing the molecular basis for signal transduction through the Zinc-Activated Channel (ZAC)

    Madjroh, Nawid, Mellou, E., Æbelø, L., Davies, P. A., Söderhielm, P. C. & Jensen, Anders A., 2021, In: Biochemical Pharmacology. 193, 18 p., 114781.

    Research output: Contribution to journalJournal articleResearchpeer-review

  364. Published

    Quadrivalent human papillomavirus vaccination and non-targeted infectious disease hospitalisation: Population-based self-controlled case series analysis

    Hviid, Anders Peter & Laksafoss, A., 2021, In: The Lancet Regional Health - Europe. 10, 7 p., 100189.

    Research output: Contribution to journalJournal articleResearchpeer-review

  365. Published

    Radiolabeled HOCPCA as a highly useful tool in drug discovery and pharmacology

    Griem-Krey, Nane, Frølund, Bente, Marek, A. & Wellendorph, Petrine, 2021, In: Journal of Labelled Compounds and Radiopharmaceuticals. 64, 2, 77 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  366. Published

    Rearrangement of Thiodepsipeptides by S → N Acyl Shift Delivers Homodetic Autoinducing Peptides

    Gless, Bengt, Bejder, Benjamin Svejdal, Monda, Fabrizio, Bojer, Martin Saxtorph, Ingmer, Hanne & Olsen, Christian Adam, 2021, In: Journal of the American Chemical Society. 143, 28, p. 10514–10518

    Research output: Contribution to journalJournal articleResearchpeer-review

  367. Published