Albert Jelke Kooistra
Associate Professor
Peptides and Proteins
Jagtvej 162, 2100 København Ø
Member of:
Albert is an associate professor in Data Science for Drug Design (DSDD) at the University of Copenhagen (DK), where he also heads the Pharmaceutical Data Science team and the Data and Computing Facility. His DSDD research group focuses on developing and applying cutting-edge and data-driven technologies to ultimately advance the development of new therapeutics. With expertise in structural bioinformatics, cheminformatics, computer-aided drug discovery & design, research tool/database development and applying machine learning/AI approaches. He is also the founder and developer of KLIFS (https://klifs.net), a structural kinase database that is widely used by >1500 researchers every month for kinase and kinase inhibitor research. In addition, he serves as senior scientific expert at the quantum software company Kvantify.
After a masters in bioinformatics, he obtained his PhD degree in computational medicinal chemistry at the Vrije Universiteit Amsterdam (NL), and subsequently did postdoctoral work in molecular dynamics, structural bioinformatics, and cheminformatics. For his continued work enabling research via scientific databases, he received the 2021 MGMS Frank Blaney award from the Molecular Graphics and Modelling Society.
Selected publications
- Published
GPCRdb in 2023: state-specific structure models using AlphaFold2 and new ligand resources
Pándy-Szekeres, Gáspár, Caroli, J., Mamyrbekov, A., Kermani, A. A., Keserű, G. M., Kooistra, Albert Jelke & Gloriam, David E., 2023, In: Nucleic Acids Research. 51, D1, p. D395–D402Research output: Contribution to journal › Journal article › Research › peer-review
- Published
KLIFS: an overhaul after the first 5 years of supporting kinase research
Kanev, G. K., de Graaf, C., Westerman, B. A., de Esch, I. J. P. & Kooistra, Albert Jelke, 2021, In: Nucleic Acids Research. 49, D1, p. D562-D569Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structure of the class D GPCR Ste2 dimer coupled to two G proteins
Velazhahan, V., Ma, N., Pándy-Szekeres, Gáspár, Kooistra, Albert Jelke, Lee, Y., Gloriam, David E., Vaidehi, N. & Tate, C. G., 2021, In: Nature. 589, p. 148-153 +app 24 ppResearch output: Contribution to journal › Journal article › Research › peer-review
The Landscape of Atypical and Eukaryotic Protein Kinases
Kanev, G. K., de Graaf, C., de Esch, I. J. P., Leurs, R., Würdinger, T., Westerman, B. A. & Kooistra, Albert Jelke, Nov 2019, In: Trends in Pharmacological Sciences. 40, 11, p. 818-832 15 p.Research output: Contribution to journal › Review › Research › peer-review
Chemical Diversity in the G Protein-Coupled Receptor Superfamily
Vass, M., Kooistra, Albert Jelke, Yang, D., Stevens, R. C., Wang, M. W. & de Graaf, C., 1 May 2018, In: Trends in Pharmacological Sciences. 39, 5, p. 494-512 19 p.Research output: Contribution to journal › Review › Research › peer-review
ID: 196033213
Most downloads
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96
downloads
GPCRdb in 2021: integrating GPCR sequence, structure and function
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
57
downloads
The Landscape of Atypical and Eukaryotic Protein Kinases
Research output: Contribution to journal › Review › Research › peer-review
-
52
downloads
KLIFS: an overhaul after the first 5 years of supporting kinase research
Research output: Contribution to journal › Journal article › Research › peer-review
Published