Anne-Marie Heegaard

Anne-Marie Heegaard

Professor


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1 - 50 out of 82Page size: 50
  1. 2024
  2. Published

    Finding new analgesics: Computational pharmacology faces drug discovery challenges

    Barakat, Ahmed, Munro, G. & Heegaard, Anne-Marie, 2024, In: Biochemical Pharmacology. 222, 21 p., 116091.

    Research output: Contribution to journal › Review › Research › peer-review

  3. Published

    Topical Neuropeptide Y for Ischemic Skin Wounds

    Stangerup, T., Gjerdrum, Lise Mette Rahbek, Bzorek, M., Andersen, L., Heegaard, Anne-Marie, Jørgensen, Lars Nannestad & Ågren, Magnus, 2024, In: International Journal of Molecular Sciences. 25, 6, 14 p., 3346.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. 2023
  5. Published

    Metastatic Infiltration of Nervous Tissue and Periosteal Nerve Sprouting in Multiple Myeloma-Induced Bone Pain in Mice and Human

    Diaz-delCastillo, M., Palasca, O., Nemler, T. T., Thygesen, D. M., Chávez-Saldaña, N. A., Vázquez-Mora, J. A., Ponce Gomez, L. Y., Jensen, L. J., Evans, H., Andrews, R. E., Mandal, A., Neves, D., Mehlen, P., Caruso, J. P., Dougherty, P. M., Price, T. J., Chantry, A., Lawson, M. A., Andersen, T. L., Jimenez-Andrade, J. M. & 1 others, Heegaard, Anne-Marie, 2023, In: The Journal of Neuroscience. 43, 29, p. 5414-5430

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. 2022
  7. Published

    Fibrous dysplasia animal models: A systematic review

    Hopkins, Chelsea, de Castro, L. F., Corsi, A., Boyce, A., Collins, M. T., Riminucci, M. & Heegaard, Anne-Marie, 2022, In: Bone. 155, 13 p., 116270.

    Research output: Contribution to journal › Review › Research › peer-review

  8. Published

    Myeloma-induced bone pain: lessons learnt from a localized, immunocompetent mouse model

    Diaz-delCastillo, M., Nemler, T., Thygesen, D. M., Chavez-Saldana, N. A., Vazquez-Mora, J. A., Palasca, Oana, Jensen, Lars Juhl, Evans, H., Andrews, R. E., Mandal, A., Chantry, A. D., Lawson, M. A., Andersen, T., Jimenez-Andrade, J. M. & Heegaard, Anne-Marie, 2022, In: Clinical Lymphoma, Myeloma & Leukemia. 22, Suppl., p. S108-S108 P-133.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  9. Published

    Neuronal Sprouting and Reorganization in Bone Tissue Infiltrated by Human Breast Cancer Cells

    Hansen, R. B., Sayilekshmy, M., Sørensen, M. S., Jørgensen, A. H., Kanneworff, Ida Buur, Bengtsson, E. K. E., Grum-schwensen, T. A., Petersen, Michael Mørk, Ejersted, C., Andersen, Thomas Lund, Andreasen, C. M. & Heegaard, Anne-Marie, 2022, In: Frontiers in Pain Research. 3, p. 1-8 887747.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Neuropathic-like Pain in Fibrous Dysplasia/McCune-Albright Syndrome

    Spencer, T. L., Watts, L., Soni, A., Pinedo-Villanueva, R., Heegaard, Anne-Marie, Boyce, A. M. & Javaid, M. K., 2022, In: The Journal of clinical endocrinology and metabolism. 107, 6, p. e2258-e2266

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Systematic review and meta-analysis of studies in which burrowing behaviour was assessed in rodent models of disease-associated persistent pain

    Zhang, X. Y., Barakat, Ahmed, Diaz-delCastillo, M., Vollert, J., Sena, E. S., Heegaard, Anne-Marie, Rice, A. S. C. & Soliman, N., 2022, In: Pain. 163, 11, p. 2076-2102

    Research output: Contribution to journal › Review › Research › peer-review

  12. 2021
  13. Published

    Bone Pain in Multiple Myeloma (BPMM)—A Protocol for a Prospective, Longitudinal, Observational Study

    Diaz-delcastillo, M., Andrews, R. E., Mandal, A., Andersen, T. L., Chantry, A. D. & Heegaard, Anne-Marie, 2021, In: Cancers. 13, 7, 13 p., 1596.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Multiple myeloma—A painful disease of the bone marrow

    Diaz-delcastillo, M., Chantry, A. D., Lawson, M. A. & Heegaard, Anne-Marie, 2021, In: Seminars in Cell and Developmental Biology. 112, p. 49-58

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    The nociceptin/orphanin FQ receptor system as a target to alleviate cancer-induced bone pain in rats: Model validation and pharmacological evaluation

    Sliepen, S. H. J., Korioth, J., Christoph, T., Tzschentke, T. M., Diaz-delCastillo, M., Heegaard, Anne-Marie & Rutten, K., 2021, In: British Journal of Pharmacology. 178, 9, p. 1995-2007 13 p., 14899.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Vitamin D levels and the risk of prostate cancer and prostate cancer mortality

    Stroomberg, Hein Vincent, Vojdeman, F. J., Madsen, C. M., Helgstrand, J. T., Schwarz, Peter, Heegaard, Anne-Marie, Olsen, A., Tjønneland, Anne, Struer Lind, B., Brasso, K., Jørgensen, Henrik Løvendahl & Røder, Andreas, 2021, In: Acta Oncologica. 60, 3, p. 316-322 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. 2020
  18. Published

    Differential Pain-Related Behaviors and Bone Disease in Immunocompetent Mouse Models of Myeloma

    Diaz-delCastillo, M., Kamstrup, D., Olsen, R. B., Hansen, R. B., Pembridge, T., Simanskaite, B., Jimenez-Andrade, J. M., Lawson, M. A. & Heegaard, Anne-Marie, 2020, In: JBMR Plus. 4, 2, 14 p., e10252.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Hypophosphatemic Hypovitaminosis D Induces Osteomalacia in the Adult Female Rat

    Durup, D., Diaz-delCastillo, M., Morgenlykke, J., Jensen, Lars Thorbjørn, Frandsen, E., Abelson, Klas, Pedersen, L., Lykkesfeldt, Jens, Ding, M., Jørgensen, Niklas Rye, Syberg, S., Petersen, S. & Heegaard, Anne-Marie, 2020, In: Endocrinology. 161, 8, bqaa100.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Modulation of Rat Cancer-Induced Bone Pain is Independent of Spinal Microglia Activity

    Diaz-delCastillo, M., Hansen, R. B., Appel, C. K., Nielsen, Signe Lykke, Nielsen, S. N., Karyniotakis, K., Dahl, L. M., Andreasen, R. B. & Heegaard, Anne-Marie, 2020, In: Cancers. 12, 10, 19 p., 2740.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. 2019
  22. Published

    Innervation is higher above Bone Remodeling Surfaces and in Cortical Pores in Human Bone: Lessons from patients with primary hyperparathyroidism

    Sayilekshmy, M., Hansen, R. B., Delaissé, J. M., Rolighed, L., Andersen, T. L. & Heegaard, Anne-Marie, 1 Dec 2019, In: Scientific Reports. 9, 1, 14 p., 5361.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Exploring the Patients' Perception of Background and Breakthrough Pain: A McGill Pain Questionnaire Inquiry in Patients with Bone Cancer Pain

    Hansen, R. R., Heegaard, Anne-Marie, Frost, C. Ø., Johnsen, A. T. & Sonne, N. M., Aug 2019, In: Journal of Palliative Medicine. 22, 8, p. 881-883

    Research output: Contribution to journal › Letter › Research › peer-review

  24. Published

    Best practice management guidelines for fibrous dysplasia/McCune-Albright syndrome: a consensus statement from the FD/MAS international consortium

    Javaid, M. K., Boyce, A., Appelman-Dijkstra, N., Ong, J., Defabianis, P., Offiah, A., Arunde, P., Shaw, N., Dal Pos, V., Underhil, A., Portero, D., Heral, L., Heegaard, A-M., Masi, L., Monsell, F., Stanton, R., Dijkstra, P. D. S., Brandi, M. L., Chapurlat, R., Hamdy, N. A. T. & 1 others, Collins, M. T., 13 Jun 2019, In: Orphanet Journal of Rare Diseases. 14, 19 p., 139.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Decitabine attenuates nociceptive behavior in a murine model of bone cancer pain

    Appel, C. K., Scheff, N. N., Viet, C. T., Schmidt, B. L. & Heegaard, Anne-Marie, 1 Mar 2019, In: Pain. 160, 3, p. 619-631

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Chronic high dose P2X7 receptor inhibition exacerbates cancer-induced bone pain

    Falk, S., Appel, C. K., Bennedbæk, H. B., Al-Dihaissy, T., Unger, A., Dinkel, K. & Heegaard, Anne-Marie, 15 Feb 2019, In: European Journal of Pharmacology. 845, p. 48-55 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Cancer-induced Bone Pain Impairs Burrowing Behaviour in Mouse and Rat

    Sliepen, S. H. J., Diaz-Delcastillo, M., Korioth, J., Olsen, R. B., Appel, C. K., Christoph, T., Heegaard, Anne-Marie & Rutten, K., 2019, In: In Vivo. 33, 4, p. 1125-1132 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Vitamin D levels and cancer incidence in 217,244 individuals from primary health care in Denmark

    Vojdeman, F. J., Madsen, C. M., Frederiksen, K., Durup, D., Olsen, A., Hansen, L., Heegaard, Anne-Marie, Lind, B., Tjønneland, Anne, Jørgensen, Henrik Løvendahl & Schwarz, Peter, 2019, In: International Journal of Cancer. 145, 2, p. 338-346 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. 2018
  30. Published

    Neuropeptide Y and its involvement in chronic pain

    Diaz-delCastillo, M., Woldbye, David Paul Drucker & Heegaard, Anne-Marie, 1 Sep 2018, In: Neuroscience. 387, p. 162-169 8 p.

    Research output: Contribution to journal › Review › Research › peer-review

  31. Published

    Neuropeptide Y is Up-regulated and Induces Antinociception in Cancer-induced Bone Pain.

    Diaz del Castillo, M., Christiansen, S. H., Appel, C., Falk, S., Woldbye, David Paul Drucker & Heegaard, Anne-Marie, 29 May 2018, In: Neuroscience. 384, p. 111-119

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    The β-lactam clavulanic acid mediates glutamate transport-sensitive pain relief in a rat model of neuropathic pain

    Kristensen, P. J., Gegelashvili, G., Munro, G., Heegaard, Anne-Marie & Bjerrum, Ole Jannik, Feb 2018, In: European Journal of Pain. 22, 2, p. 282-294

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    The effect of gender on early colonic anastomotic wound healing

    Kjaer, Marie, Kristjánsdóttir, H., Andersen, L., Heegaard, Anne-Marie, Ågren, Magnus & Jørgensen, Lars Nannestad, 2018, In: International Journal of Colorectal Disease. 33, 9, p. 1269-1276 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. 2017
  35. Published

    Distribution of Nerve Fibers in Human Bone and their Association to Bone Remodeling Events and Vascular Structures.

    Sayilekshmy, M., Hansen, R. R., Delaisse, J., Rolighed, L., Heegaard, Anne-Marie & Andersen, T. L., Dec 2017, In: Journal of Bone and Mineral Research. 32, p. S196-S196

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  36. Published

    Quantification of the Pharmacodynamic Interaction of Morphine and Gabapentin Using a Response Surface Approach

    Papathanasiou, T., Juul, R. V., Gabel-Jensen, C., Kreilgaard, M., Heegaard, Anne-Marie & Lund, Trine Meldgaard, 1 Nov 2017, In: AAPS Journal. 19, 6, p. 1804–1813 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    The Src family kinase inhibitor dasatinib delays pain-related behaviour and conserves bone in a rat model of cancer-induced bone pain

    Appel, C. K., Gallego-Pedersen, S., Andersen, L., Kristensen, S. B., Ding, M., Falk, S., Sayilekshmy, M., Gabel-Jensen, C. & Heegaard, Anne-Marie, 6 Jul 2017, In: Scientific Reports. 7, 1, 14 p., 4792.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Vendor-derived differences in injury-induced pain phenotype and pharmacology of Sprague-Dawley rats: Does it matter?

    Kristensen, P. J., Heegaard, Anne-Marie, Hestehave, Sara, Jeggo, R. D., Bjerrum, Ole Jannik & Munro, G., Apr 2017, In: European Journal of Pain. 21, 4, p. 692-704 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. 2016
  40. Published

    Bone pain: current and future treatments

    Frost, C. Ø., Hansen, R. R. & Heegaard, Anne-Marie, Jun 2016, In: Current Opinion in Pharmacology. 28, p. 31-7 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Co-administration of morphine and gabapentin leads to dose dependent synergistic effects in a rat model of postoperative pain

    Papathanasiou, T., Juul, R. V., Heegaard, Anne-Marie, Kreilgaard, M. & Lund, Trine Meldgaard, 2016, In: European Journal of Pharmaceutical Sciences. 82, p. 97–105 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. 2015
  43. Published

    Response surface analysis of synergistic interactions of morphine and gabapentin in a rat model of postoperative pain.

    Papathanasiou, T., Juul, R. V., Heegaard, Anne-Marie, Kreilgaard, M. & Lund, Trine Meldgaard, 19 Oct 2015.

    Research output: Contribution to conference › Poster › Research

  44. Published

    A reverse J-shaped association between serum 25-hydroxyvitamin D and cardiovascular disease mortality - the CopD-study

    Durup, D., Jørgensen, Henrik Løvendahl, Christensen, J., Tjønneland, Anne, Olsen, A., Halkjær, J., Lind, B., Heegaard, Anne-Marie & Schwarz, Peter, 24 Feb 2015, In: The Journal of clinical endocrinology and metabolism. 100, 6, p. 2339-46 8 p., jc20144551.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    P2X7 receptor-mediated analgesia in cancer-induced bone pain

    Falk, S., D. Schwab, S., Frøsig-Jørgensen, M., Clausen, Rasmus Prætorius, Dickenson, A. & Heegaard, Anne-Marie, 13 Feb 2015, In: Neuroscience. 291, p. 93–105 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    COMBINATION OF MORPHINE AND GABAPENTIN LEADS TO SYNERGISTIC EFFECTS IN A RAT MODEL OF POSTOPERATIVE PAIN

    Papathanasiou, T., Juul, R. V., Heegaard, Anne-Marie, Kreilgaard, M. & Lund, Trine Meldgaard, 14 Jan 2015.

    Research output: Contribution to conference › Poster › Research

  47. Published

    Effect of sex in the MRMT-1 model of cancer-induced bone pain

    Falk, S., Al-Dihaissy, T., Mezzanotte, L. & Heegaard, Anne-Marie, 2015, In: F1000Research. 4, 445, p. 1-18 18 p., 445.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Randall Selitto pressure algometry for assessment of bone-related pain in rats

    Falk, S., Ipsen, David Højland, Appel, C. K., Ugarak, A., Durup, D., Dickenson, A. H. & Heegaard, Anne-Marie, 2015, In: European Journal of Pain. 19, 3, p. 305-312 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Spinal neuronal correlates of tapentadol analgesia in cancer pain: A back-translational approach

    Falk, S., Patel, R., Heegaard, Anne-Marie, Mercadante, S. & Dickenson, A. H., 2015, In: European Journal of Pain. 19, 2, p. 152-158 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. 2014
  51. Published

    Pain without nociceptors? Nav1.7-independent pain mechanisms

    Minett, M. S., Falk, S., Santana-Varela, S., Bogdanov, Y. D., Nassar, M. A., Heegaard, Anne-Marie & Wood, J. N., 30 Jan 2014, In: Cell Reports. 6, 2, p. 245-246

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. 2013
  53. Published

    Impaired behavioural pain responses in hph-1 mice with inherited deficiency in GTP cyclohydrolase 1 in models of inflammatory pain

    Nasser, A., Bjerrum, Ole Jannik, Heegaard, Anne-Marie, Møller, A. T., Larsen, M., Dalbøge, L. S., Dupont, E., Jensen, T. S. & Møller, L. B., 19 Feb 2013, In: Molecular Pain. 9, p. 5

    Research output: Contribution to journal › Journal article › Research › peer-review

  54. Published

    Influence of sex differences on the progression of cancer-induced bone pain

    Falk, S., Uldall, M., Appel, C., Ding, M. & Heegaard, Anne-Marie, 2013, In: Anticancer Research. 33, 5, p. 1963-1969

    Research output: Contribution to journal › Journal article › Research › peer-review

  55. 2012
  56. Published

    A reverse J-shaped association of all-cause mortality with serum 25-hydroxyvitamin D in general practice: The CopD study

    Durup, D. T., Jørgensen, Henrik Løvendahl, Christensen, J., Schwarz, P., Heegaard, Anne-Marie & Lind, B., 1 Aug 2012, In: Journal of Clinical Endocrinology and Metabolism. 97, 8, p. 2644-52 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  57. Published

    A reverse J-shaped association of all-cause mortality with serum 25-hydroxyvitamin D in general practice, the CopD study

    Durup, D., Jørgensen, H. L., Christensen, J., Schwarz, Peter, Heegaard, Anne-Marie & Lind, B., 2012, In: Journal of Clinical Endocrinology and Metabolism. 97, 8, p. 2644 –2652

    Research output: Contribution to journal › Journal article › Research › peer-review

  58. Published

    Chronic administration of the selective P2X3, P2X2/3 receptor antagonist, A-317491, transiently attenuates cancer-induced bone pain in mice

    Hansen, R. R., Nasser, A., Falk, S., Baldvinsson, S. B., Ohlsson, P. H., Bahl, J. M. C., Jarvis, M. F., Ding, M. & Heegaard, Anne-Marie, 2012, In: European Journal of Pharmacology. 688, 1-3, p. 27-34 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  59. Published

    The role of purinergic receptors in cancer-induced bone pain

    Falk, S., Uldall, M. & Heegaard, Anne-Marie, 2012, In: Journal of Osteoporosis. p. Article ID 758181 12 p.

    Research output: Contribution to journal › Review › Research › peer-review

  60. 2011
  61. Published

    Nonselective matrix metalloproteinase but not tumor necrosis factor-a inhibition effectively preserves the early critical colon anastomotic integrity

    Ågren, M. S., Andersen, T. L., Andersen, L., Schiødt, C. B., Surve, V., Andreassen, T. T., Risteli, J., Franzén, L. E., Delaissé, J., Heegaard, Anne-Marie & Jørgensen, Lars Nannestad, 2011, In: International Journal of Colorectal Disease. 26, 3, p. 329-337 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  62. Published

    P2X7 receptor-deficient mice are susceptible to bone cancer pain

    Hansen, R. R., Nielsen, C. K., Nasser, A., Thomsen, S. I. M., Eghorn, L. F., Pham, Y., Schulenburg, C., Syberg, S., Ding, M., Stojilkovic, S. S., Jorgensen, N. R. & Heegaard, Anne-Marie, 2011, In: Pain. 152, 8, p. 1766-76 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  63. Published

    The hph-1 mouse mutant deficient in tetrahydrobiopterin show reduced acute and chronic inflammatory pain

    Bjerrum, Ole Jannik, Nasser, A. & Heegaard, Anne-Marie, 2011.

    Research output: Contribution to conference › Poster › Research › peer-review

  64. 2010
  65. Published

    Effect of GTP-cyclohydrolase deficiency in the HPH-1mouse on acute and inflammatory pain

    Nasser, A., Bjerrum, Ole Jannik & Heegaard, Anne-Marie, 2010.

    Research output: Contribution to conference › Conference abstract for conference › Communication

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