Arne Schousboe

Arne Schousboe

Professor, emeritus


  1. 2023
  2. Accepted/In press

    A tribute to Leif Hertz: The historical context of his pioneering studies of the roles of astrocytes in brain energy metabolism, neurotransmission, cognitive functions, and pharmacology identifies important, unresolved topics for future studies

    Dienel, G. A., Schousboe, Arne, McKenna, M. C. & Rothman, D. L., 2023, (Accepted/In press) In: Journal of Neurochemistry.

    Research output: Contribution to journalReviewResearchpeer-review

  3. Published

    Astrocytes regulate inhibitory neurotransmission through GABA uptake, metabolism, and recycling

    Andersen, Jens Velde, Schousboe, Arne & Wellendorph, Petrine, 2023, In: Essays in Biochemistry. 67, 1, p. 77-91

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Accepted/In press

    Deletion of CaMKIIα disrupts glucose metabolism, glutamate uptake, and synaptic energetics in the cerebral cortex

    Andersen, Jens Velde, Westi, Emil Winther, Griem-Krey, Nane, Skotte, Niels Henning, Schousboe, Arne, Aldana, Blanca & Wellendorph, Petrine, 2023, (Accepted/In press) In: Journal of Neurochemistry.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Glial Glutamine Homeostasis in Health and Disease

    Andersen, J. V. & Schousboe, Arne, 2023, In: Neurochemical Research. 48, p. 1100–1128

    Research output: Contribution to journalReviewResearchpeer-review

  6. Published

    Glutamate Neurotoxicity Related to Energy Failure

    Schousboe, Arne, 2023, Handbook of Neurotoxicity. 2 ed. Springer, p. 803-815 13 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  7. Published

    Milestone Review: Metabolic dynamics of glutamate and GABA mediated neurotransmission — The essential roles of astrocytes

    Andersen, Jens Velde & Schousboe, Arne, 2023, In: Journal of Neurochemistry. 166, 2, p. 109-137

    Research output: Contribution to journalReviewResearchpeer-review

  8. Published

    The history of Danish neuroscience

    Paulson, Olaf B., Schousboe, Arne & Hultborn, Hans, 2023, In: European Journal of Neuroscience. 58, 4, p. 2893-2960

    Research output: Contribution to journalEditorialResearchpeer-review

  9. 2022
  10. Published

    Astrocyte energy and neurotransmitter metabolism in Alzheimer's disease: Integration of the glutamate/GABA-glutamine cycle

    Andersen, Jens Velde, Schousboe, Arne & Verkhratsky, A., 2022, In: Progress in Neurobiology. 217, 24 p., 102331.

    Research output: Contribution to journalReviewResearchpeer-review

  11. Published

    Low cerebral energy metabolism in hepatic encephalopathy reflects low neuronal energy demand. Role of ammonia-induced increased GABAergic tone

    Sorensen, M., Walls, Anne Byriel, Dam, G., Bak, Lasse Kristoffer, Andersen, Jens Velde, Ott, P., Vilstrup, H. & Schousboe, Arne, 2022, In: Analytical Biochemistry. 654, 4 p., 114766.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. 2021
  13. Published

    Amino acids: Glutamate dehydrogenase: An anaplerotic enzyme in neurons and an energy producing enzyme in astrocytes

    Schousboe, Arne & Aldana, Blanca, 29 Jul 2021, Encyclopedia of Biological Chemistry: Third Edition. Elsevier, Vol. 1. p. 51-55 5 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  14. Published

    Deficient astrocyte metabolism impairs glutamine synthesis and neurotransmitter homeostasis in a mouse model of Alzheimer's disease

    Andersen, Jens Velde, Christensen, S. K., Westi, Emil Winther, Diaz-delcastillo, M., Tanila, H., Schousboe, Arne, Aldana, Blanca & Waagepetersen, Helle S., 2021, In: Neurobiology of Disease. 148, 13 p., 105198.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Downregulation of GABA Transporter 3 (GAT3) is Associated with Deficient Oxidative GABA Metabolism in Human Induced Pluripotent Stem Cell-Derived Astrocytes in Alzheimer's Disease

    Salcedo, C., Wagner, A., Andersen, Jens Velde, Vinten, K. T., Waagepetersen, Helle S., Schousboe, Arne, Freude, Kristine & Aldana, Blanca, 2021, In: Neurochemical Research. 46, p. 2676–2686

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Glutamate Dehydrogenase Is Important for Ammonia Fixation and Amino Acid Homeostasis in Brain During Hyperammonemia

    Voss, C. M., Arildsen, L., Nissen, J. D., Waagepetersen, Helle S., Schousboe, Arne, Maechler, P., Ott, P., Vilstrup, H. & Walls, Anne Byriel, 2021, In: Frontiers in Neuroscience. 15, 18 p., 646291.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Glutamate metabolism and recycling at the excitatory synapse in health and neurodegeneration

    Andersen, Jens Velde, Markussen, K. H., Jakobsen, Emil, Schousboe, Arne, Waagepetersen, Helle S., Rosenberg, P. A. & Aldana, Blanca, 2021, In: Neuropharmacology. 196, 14 p., 108719.

    Research output: Contribution to journalReviewResearchpeer-review

  18. Published

    Hippocampal disruptions of synaptic and astrocyte metabolism are primary events of early amyloid pathology in the 5xFAD mouse model of Alzheimer's disease

    Andersen, Jens Velde, Skotte, Niels Henning, Christensen, S. K., Polli, F. S., Shabani, M., Markussen, K. H., Haukedal, H., Westi, Emil Winther, Diaz-delCastillo, M., Sun, R. C., Kohlmeier, Kristi Anne, Schousboe, Arne, Gentry, M. S., Tanila, H., Freude, Kristine, Aldana, Blanca, Mann, Matthias & Waagepetersen, Helle S., 2021, In: Cell Death & Disease. 12, 11, 13 p., 954 .

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Preface for the Vladimir Parpura Honorary Issue of Neurochemical Research

    Verkhratsky, A., Schousboe, Arne & Zorec, R., 2021, In: Neurochemical Research. 46, 10, p. 2507-2511

    Research output: Contribution to journalEditorialResearch

  20. Published

    Two Metabolic Fuels, Glucose and Lactate, Differentially Modulate Exocytotic Glutamate Release from Cultured Astrocytes

    Montana, V., Flint, D., Waagepetersen, Helle S., Schousboe, Arne & Parpura, V., 2021, In: Neurochemical Research. 46, p. 2551–2579

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. 2020
  22. Published

    Astrocytic Metabolism Focusing on Glutamate Homeostasis: A Short Review Dedicated to Vittorio Gallo

    Schousboe, Arne, 2020, In: Neurochemical Research. 45, 3, p. 522-525

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published
  24. Published

    Pharmacological Characterization of a Betaine/GABA Transporter 1 (BGT1) Inhibitor Displaying an Unusual Biphasic Inhibition Profile and Anti-seizure Effects

    Lie, M. E. K., Kickinger, S., Skovgaard-Petersen, J., Ecker, G. F., Clausen, Rasmus Prætorius, Schousboe, Arne, White, H. S. & Wellendorph, Petrine, 2020, In: Neurochemical Research. 45, p. 1551–1565

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Preface for the Vittorio Gallo Honorary Issue of Neurochemical Research

    Schousboe, Arne, 2020, In: Neurochemical Research. 45, 3, p. 519-521

    Research output: Contribution to journalEditorialResearchpeer-review

  26. 2019
  27. Published

    Astrocytic pyruvate carboxylation: Status after 35 years

    Schousboe, Arne, Waagepetersen, Helle S. & Sonnewald, U., 1 Jan 2019, In: Journal of Neuroscience Research. 97, p. 890-896

    Research output: Contribution to journalReviewResearchpeer-review

  28. Published

    Metabolic signaling in the brain and the role of astrocytes in control of glutamate and GABA neurotransmission

    Schousboe, Arne, 2019, In: Neuroscience Letters. 689, p. 11-13 3 p.

    Research output: Contribution to journalReviewResearchpeer-review

  29. Published

    Preface: Special issue on neurotransmitter transporters

    Chaudhry, F. A., Loland, Claus Juul, Ortega, A. & Schousboe, Arne, 2019, In: Neuropharmacology. 161, 1 p., 107859.

    Research output: Contribution to journalEditorialResearchpeer-review

  30. Published

    Special Issue in Honor of Dr. Elias K. Michaelis

    Choi, I. & Schousboe, Arne, 2019, In: Neurochemical Research. 44, 1, p. 1-4

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    State-Dependent Changes in Brain Glycogen Metabolism

    DiNuzzo, M., Walls, Anne Byriel, Öz, G., Seaquist, E. R., Waagepetersen, Helle S., Bak, Lasse Kristoffer, Nedergaard, Maiken & Schousboe, Arne, 2019, Brain Glycogen Metabolism. DiNuzzo, M. & Schousboe, A. (eds.). Springer, p. 269-309 41 p. (Advances in Neurobiology, Vol. 23).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  32. Published

    Structural and molecular aspects of betaine-GABA transporter 1 (BGT1) and its relation to brain function

    Kickinger, S., Hellsberg, E., Frølund, Bente, Schousboe, Arne, Ecker, G. F. & Wellendorph, Petrine, 2019, In: Neuropharmacology. 161, 14 p., 107644.

    Research output: Contribution to journalReviewResearchpeer-review

  33. Published

    The 13th International Conference on Brain Energy Metabolism: "How Metabolism Dictates Neurotransmission, Function and Behavior"

    Barros, L. F., Schousboe, Arne & McKenna, M. C., 2019, In: Journal of Neuroscience Research. 97, 8, p. 849-853 5 p.

    Research output: Contribution to journalJournal articleResearch

  34. 2018
  35. Published

    Astrocytic glycogen metabolism in the healthy and diseased brain

    Bak, Lasse Kristoffer, Walls, Anne Byriel, Schousboe, Arne & Waagepetersen, Helle S., 11 May 2018, In: The Journal of Biological Chemistry. 293, 19, p. 7108-7116 9 p.

    Research output: Contribution to journalReviewResearchpeer-review

  36. 2017
  37. Published

    Misconceptions regarding basic thermodynamics and enzyme kinetics have led to erroneous conclusions regarding the metabolic importance of lactate dehydrogenase isoenzyme expression

    Bak, Lasse Kristoffer & Schousboe, Arne, Nov 2017, In: Journal of Neuroscience Research. 95, 11, p. 2098-2102 5 p.

    Research output: Contribution to journalReviewResearchpeer-review

  38. Published

    The 12th International Conference on Brain Energy Metabolism (ICBEM): "Energy Metabolism and Neuron-Glia Interactions in Brain: From Molecular Mechanisms to Novel Therapeutic Approaches"

    Yu, A. C. H., Schousboe, Arne & McKenna, M. C., Nov 2017, In: Journal of Neuroscience Research. 95, 11, p. 2095-2097 3 p.

    Research output: Contribution to journalJournal articleCommunication

  39. Published

    The novel anticonvulsant neuropeptide and galanin analogue, NAX-5055, does not alter energy and amino acid metabolism in cultured brain cells

    Aldana, Blanca, Waagepetersen, Helle S., Schousboe, Arne, White, H. S., Bulaj, G. & Walls, Anne Byriel, Nov 2017, In: Journal of Neuroscience Research. 95, 11, p. 2286-2296 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Structure-Activity Relationship, Pharmacological Characterization, and Molecular Modeling of Noncompetitive Inhibitors of the Betaine/γ-Aminobutyric Acid Transporter 1 (BGT1)

    Jørgensen, L., Al-Khawaja, A., Kickinger, S., Vogensen, S. B., Skovgaard-Petersen, J., Rosenthal, E., Borkar, N., Löffler, R., Madsen, K. K., Bräuner, Hans, Schousboe, Arne, Ecker, G. F., Wellendorph, Petrine & Clausen, Rasmus Prætorius, 9 Oct 2017, In: Journal of Medicinal Chemistry. 60, 21, p. 8834-8846

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published
  42. Published

    Delineation of the Role of Astroglial GABA Transporters in Seizure Control

    Schousboe, Arne & Madsen, K. K., Jul 2017, In: Neurochemical Research. 42, 7, p. 2019-2023

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Citrate, a Ubiquitous Key Metabolite with Regulatory Function in the CNS

    Westergaard, N., Waagepetersen, Helle S., Belhage, B. & Schousboe, Arne, Jun 2017, In: Neurochemical Research. 42, 6, p. 1583-1588 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    A Tribute to Mary C. McKenna: Glutamate as Energy Substrate and Neurotransmitter-Functional Interaction Between Neurons and Astrocytes

    Schousboe, Arne, Jan 2017, In: Neurochemical Research. 42, 1, p. 4-9 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Astrocytic GABA Transporters: Pharmacological Properties and Targets for Antiepileptic Drugs

    Schousboe, Arne, Wellendorph, Petrine, Frølund, Bente, Clausen, Rasmus Prætorius & Krogsgaard-Larsen, Povl, 2017, Glial Amino Acid Transporters. Springer, Vol. 16. p. 283-296 14 p. (Advances in Neurobiology).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterCommunication

  46. Published

    Expression of the human isoform of glutamate dehydrogenase, hGDH2, augments TCA cycle capacity and oxidative metabolism of glutamate during glucose deprivation in astrocytes

    Nissen, J. D., Lykke, K., Bryk, J., Stridh, M. H., Zaganas, I., Jensen, Dorte Skytt, Schousboe, Arne, Bak, Lasse Kristoffer, Enard, W., Pääbo, S. & Waagepetersen, Helle S., 2017, In: Glia. 65, 3, p. 474–488

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Glial GABA Transporters as Modulators of Inhibitory Signalling in Epilepsy and Stroke

    Lie, M. E. K., Al-Khawaja, A., Damgaard, M., Haugaard, A. S., Schousboe, Arne, Clarkson, A. N. & Wellendorph, Petrine, 2017, Advances in Neurobiology. Vol. 16. p. 137-167 31 p. (Advances in Neurobiology).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  48. Published

    Glutamate and ATP at the Interface Between Signaling and Metabolism in Astroglia: Examples from Pathology

    Parpura, V., Fisher, E. S., Lechleiter, J. D., Schousboe, Arne, Waagepetersen, Helle S., Brunet, S., Baltan, S. & Verkhratsky, A., 2017, In: Neurochemical Research. 42, 1, p. 19-34 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Metabolic Characterization of Acutely Isolated Hippocampal and Cerebral Cortical Slices Using [U-(13)C]Glucose and [1,2-(13)C]Acetate as Substrates

    McNair, Laura M., Kornfelt, R., Walls, Anne Byriel, Andersen, Jens Velde, Aldana, B. I., Nissen, J. D., Schousboe, Arne & Waagepetersen, Helle S., 2017, In: Neurochemical Research. 42, 3, p. 810-826 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Preface for the Mary C. McKenna Honorary Issue of Neurochemical Research

    Schousboe, Arne, 2017, In: Neurochemical Research. 42, 1, 1-3.

    Research output: Contribution to journalEditorialResearch

  51. Published

    Preface for the Ursula Sonnewald Honorary Issue of Neurochemical Research

    Schousboe, Arne, 2017, In: Neurochemical Research. 42, 6, p. 1581-1582 2 p.

    Research output: Contribution to journalEditorialResearch

  52. Published
  53. Published

    gamma-Aminobutyric Acid and Glycine Neurotransmitter Transporters

    Wellendorph, Petrine, Jacobsen, Julie, Skovgaard-Petersen, J., Jurik, A., Vogensen, S. B., Ecker, G., Schousboe, Arne, Krogsgaard-Larsen, Povl & Clausen, Rasmus Prætorius, 2017, Transporters As Drug Targets.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  54. 2016
  55. Published

    Glutamate oxidation in astrocytes: Roles of glutamate dehydrogenase and aminotransferases

    McKenna, M. C., Stridh, M. H., McNair, Laura M., Sonnewald, U., Waagepetersen, Helle S. & Schousboe, Arne, 15 Sep 2016, In: Journal of Neuroscience Research. 94, 12, p. 1561-1571 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Published

    The anticonvulsant action of the galanin receptor agonist NAX-5055 involves modulation of both excitatory- and inhibitory neurotransmission

    Walls, Anne Byriel, Flynn, S. P., West, P. J., Müller, M. S., Bak, Lasse Kristoffer, Bulaj, G., Schousboe, Arne & White, H. S., Mar 2016, In: Epilepsy Research. 121, p. 55-63 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. Published

    Neuronal Cell Death Induced by Mechanical Percussion Trauma in Cultured Neurons is not Preceded by Alterations in Glucose, Lactate and Glutamine Metabolism

    Jayakumar, A. R., Bak, Lasse Kristoffer, Rama Rao, K. V., Waagepetersen, Helle S., Schousboe, Arne & Norenberg, M. D., Feb 2016, In: Neurochemical Research. 41, 1, p. 307-15 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. Published

    40 year anniversary issue of neurochemical research

    Schousboe, Arne, 2016, In: Neurochemical Research. 41, 1-2, p. 1-2 2 p.

    Research output: Contribution to journalEditorialResearch

  59. Published

    Anaplerosis for Glutamate Synthesis in the Neonate and in Adulthood

    Brekke, E., Morken, T. S., Walls, Anne Byriel, Waagepetersen, Helle S., Schousboe, Arne & Sonnewald, U., 2016, The Glutamate/ GABA- Glutamine Cycle : Amino Acid Neurotransmitter Homeostasis. Springer, Vol. 13. p. 43-58 16 p. (Advances in Neurobiology, Vol. 13).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  60. Published

    Introduction to the Glutamate-Glutamine Cycle

    Sonnewald, U. & Schousboe, Arne, 2016, 7 p. (Advances in Neurobiology).

    Research output: Book/ReportAnthologyResearchpeer-review

  61. Published

    The Glutamine Transporters and Their Role in the Glutamate/GABA-Glutamine Cycle

    Leke, R. & Schousboe, Arne, 2016, 35 p. (Advances in Neurobiology).

    Research output: Book/ReportAnthologyResearchpeer-review

  62. 2015
  63. Published

    Glutamate neurotransmission is affected in prenatally stressed offspring

    Adrover, E., Pallarés, M. E., Baier, C. J., Monteleone, M. C., Giuliani, F. A., Waagepetersen, Helle S., Brocco, M. A., Cabrera, R., Sonnewald, U., Schousboe, Arne & Antonelli, M. C., Sep 2015, In: Neurochemistry International. 88, p. 73-87 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  64. Published

    Two isoforms of glycogen phosphorylase activated by the same signaling trains: how and why?

    Bak, Lasse Kristoffer, Mueller, M. S., Fox, R., Pedersen, Sofie E., Walls, Anne Byriel, Christiansen, Ann-Kathrin Lindahl, Jakobsen, E., Schousboe, Arne & Waagepetersen, Helle S., Aug 2015, In: Journal of Neurochemistry. 134, suppl. 1, p. 56-56 1 p., S26-01.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  65. Published

    Glucose replaces glutamate as energy substrate to fuel glutamate uptake in glutamate dehydrogenase-deficient astrocytes

    Pajęcka, K., Nissen, J. D., Stridh, M. H., Jensen, Dorte Skytt, Schousboe, Arne & Waagepetersen, Helle S., Jul 2015, In: Journal of Neuroscience Research. 93, 7, p. 1093-100 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  66. Published

    The 11th International Conference on Brain Energy Metabolism "how energy metabolism shapes brain function". Preface: Preface

    Waagepetersen, Helle S., Schousboe, Arne & McKenna, M. C., Jul 2015, In: Journal of Neuroscience Research. 93, 7, p. 985-6 2 p.

    Research output: Contribution to journalJournal articleResearch

  67. Published

    Structure activity relationship of selective GABA uptake inhibitors

    Vogensen, S. B., Jørgensen, L., Madsen, K. K., Jurik, A., Borkar, N., Rosatelli, E., Nielsen, Birgitte, Ecker, G. F., Schousboe, Arne & Clausen, Rasmus Prætorius, 15 May 2015, In: Bioorganic & Medicinal Chemistry. 23, 10, p. 2480-2488 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  68. Published

    AMPK Activation Affects Glutamate Metabolism in Astrocytes

    Voss, C. M., Pajęcka, K., Stridh, M. H., Nissen, J. D., Schousboe, Arne & Waagepetersen, Helle S., 7 Apr 2015, In: Neurochemical Research. 40, 12, p. 2431-2442 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  69. Published

    Brain glycogen: emergency fuel and dynamic function in neurotransmission

    Walls, Anne Byriel & Schousboe, Arne, Feb 2015, In: Metabolic Brain Disease. 30, 1, p. 249-249 1 p.

    Research output: Contribution to journalJournal articleResearch

  70. Published

    The Glutamine-Glutamate/GABA Cycle: Function, Regional Differences in Glutamate and GABA Production and Effects of Interference with GABA Metabolism

    Walls, Anne Byriel, Waagepetersen, Helle S., Bak, Lasse Kristoffer, Schousboe, Arne & Sonnewald, U., Feb 2015, In: Neurochemical Research. 40, 2, p. 402-9 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  71. Published

    The Subcellular Localization of GABA Transporters and Its Implication for Seizure Management

    Madsen, K. K., Hansen, Gert Helge, Danielsen, E. M. & Schousboe, Arne, Feb 2015, In: Neurochemical Research. 40, 2, p. 410-419 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  72. Published

    Glutamine and ammonia in hepatic encephalopathy

    Dadsetan, S., Waagepetersen, Helle S., Schousboe, Arne & Bak, Lasse Kristoffer, 1 Jan 2015, Glutamine in Clinical Nutrition. Springer New York LLC, p. 219-227 9 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  73. Published

    Expression of glutamine transporter isoforms in cerebral cortex of rats with chronic hepatic encephalopathy

    Leke, R., Escobar, T. D. C., Rama Rao, K. V., Silveira, T. R., Norenberg, M. D. & Schousboe, Arne, 2015, In: Neurochemistry International. 88, p. 32-37 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  74. Published

    Glutamate and ATP: The crossroads of signaling and metabolism in the brain.

    Verkhratsky, A., Schousboe, Arne & Parpura, V., 2015, Advances in Neurobiology. Schousboe, A. (ed.). USA: Springer Publishing Company, Vol. 11. p. 1-12 12 p. (Advances in Neurobiology).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterCommunication

  75. 2014
  76. Published

    Introduction to special issue in honor of Professor Povl Krogsgaard-Larsen

    Bräuner, Hans & Schousboe, Arne, Oct 2014, In: Neurochemical Research. 39, 10, p. 1845-6 2 p.

    Research output: Contribution to journalJournal articleResearch

  77. Published

    A subconvulsive dose of kainate selectively compromises astrocytic metabolism in the mouse brain in vivo

    Walls, Anne Byriel, Eyjolfsson, E. M., Schousboe, Arne, Sonnewald, U. & Waagepetersen, Helle S., Aug 2014, In: Journal of Cerebral Blood Flow and Metabolism. 34, 8, p. 1340-6 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  78. Published

    Astrocyte glycogenolysis is triggered by store-operated calcium entry and provides metabolic energy for cellular calcium homeostasis

    Müller, M. S., Fox, R., Schousboe, Arne, Waagepetersen, Helle S. & Bak, Lasse Kristoffer, Apr 2014, In: Glia. 62, 4, p. 526-34 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  79. Published

    Effects of hyperammonemia on brain energy metabolism: controversial findings in vivo and in vitro

    Schousboe, Arne, Waagepetersen, Helle S., Leke, R. & Bak, Lasse Kristoffer, 1 Mar 2014, In: Metabolic Brain Disease. 29, 4, p. 913-917 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  80. Published

    Effect of glutamine synthetase inhibition on brain and interorgan ammonia metabolism in bile duct ligated rats

    Fries, A. W., Dadsetan, S., Keiding, S., Bak, Lasse Kristoffer, Schousboe, Arne, Waagepetersen, Helle S., Simonsen, M., Ott, P., Vilstrup, H. & Sørensen, M., Mar 2014, In: Journal of Cerebral Blood Flow and Metabolism. 34, 3, p. 460-6 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  81. Published

    Metabolic mapping of astrocytes and neurons in culture using stable isotopes and gas chromatography-mass spectrometry (GC-MS)

    Walls, Anne Byriel, Bak, Lasse Kristoffer, Sonnewald, U., Schousboe, Arne & Waagepetersen, Helle S., 1 Jan 2014, In: Neuromethods. 90, p. 73-105 33 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  82. Published

    Expression of glutamate decarboxylase (GAD) mRNA in the brain of bile duct ligated rats serving as a model of hepatic encephalopathy

    Leke, R., Silveira, T., Escobar, T. & Schousboe, Arne, 2014, In: Neurochemical Research. 39, 3, p. 605-611 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  83. Published

    Glutamate dehydrogenase isoforms with N-terminal (His)6- or FLAG-tag retain their kinetic properties and cellular localization

    Pajęcka, K., Nielsen, C. W., Hauge, A., Zaganas, I., Bak, Lasse Kristoffer, Schousboe, Arne, Plaitakis, A. & Waagepetersen, Helle S., 2014, In: Neurochemical Research. 39, 3, p. 487-99 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  84. Published

    Glutamate metabolism in the brain focusing on astrocytes

    Schousboe, Arne, Scafidi, S., Bak, Lasse Kristoffer, Waagepetersen, Helle S. & McKenna, M. C., 2014, In: Advances in Neurobiology. 11, p. 13-30 18 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  85. Published

    Oxidative metabolism of astrocytes is not reduced in hepatic encephalopathy: a PET study with [(11)C]acetate in humans

    Iversen, P., Mouridsen, K., Hansen, M. B., Jensen, S. B., Sørensen, M., Bak, Lasse Kristoffer, Waagepetersen, Helle S., Schousboe, Arne, Ott, P., Vilstrup, H., Keiding, S. & Gjedde, Albert, 2014, In: Frontiers in Neuroscience. 8, p. 353

    Research output: Contribution to journalJournal articleResearchpeer-review

  86. Published

    The GABA Synapse as a Target for Antiepileptic Drugs: A Historical Overview Focused on GABA Transporters

    Schousboe, Arne, Madsen, K. K., Barker-Haliski, M. L. & White, H. S., 2014, In: Neurochemical Research. 39, 10, p. 1980-1987 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  87. 2013
  88. Published

    Astrocytic control of biosynthesis and turnover of the neurotransmitters glutamate and GABA

    Schousboe, Arne, Bak, Lasse Kristoffer & Waagepetersen, Helle S., 15 Aug 2013, In: Frontiers in Endocrinology. 4, 102.

    Research output: Contribution to journalJournal articleResearchpeer-review

  89. Published

    Brain alanine formation as an ammonia-scavenging pathway during hyperammonemia: effects of glutamine synthetase inhibition in rats and astrocyte-neuron co-cultures

    Dadsetan, S., Kukolj, E., Bak, Lasse Kristoffer, Sørensen, M., Ott, P., Vilstrup, H., Schousboe, Arne, Keiding, S. & Waagepetersen, Helle S., Aug 2013, In: Journal of Cerebral Blood Flow and Metabolism. 33, 8, p. 1235-41 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  90. Published

    Complex actions of ionomycin in cultured cerebellar astrocytes affecting both calcium-induced calcium release and store-operated calcium entry

    Müller, M. S., Obel, L. L. F., Waagepetersen, Helle S., Schousboe, Arne & Bak, Lasse Kristoffer, Jun 2013, In: Neurochemical Research. 38, 6, p. 1260-5 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  91. Published

    The effect of pH and ADP on ammonia affinity for human glutamate dehydrogenases

    Zaganas, I., Pajecka, K., Nielsen, C. W., Schousboe, Arne, Waagepetersen, Helle S. & Plaitakis, A., Jun 2013, In: Metabolic Brain Disease. 28, 2, p. 127-131 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  92. Published

    Glutamate dehydrogenase Isoforms with N-Terminal (His)6- or FLAG-tag retain their kinetic properties and cellular localization

    Pajecka, K., Nielsen, C. W., Hauge, A., Zaganas, I., Bak, Lasse Kristoffer, Schousboe, Arne, Plaitakis, A. & Waagepetersen, Helle S., 26 Apr 2013, In: Neurochemical Research. 39, 3, p. 487-499

    Research output: Contribution to journalJournal articleResearchpeer-review

  93. Published

    Selective mGAT2 (BGT-1) GABA Uptake Inhibitor: Design, synthesis and pharmacological characterization

    Vogensen, S. B., Jørgensen, L., Madsen, K. K., Borkar, N. N., Wellendorph, Petrine, Skovgaard-Petersen, J., Schousboe, Arne, White, H. S., Krogsgaard-Larsen, Povl & Clausen, Rasmus Prætorius, 11 Feb 2013, In: Journal of Medicinal Chemistry. 56, 5, p. 2160-2164 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  94. Published

    Hepatic encephalopathy is associated with decreased cerebral oxygen metabolism and blood flow, not increased ammonia uptake

    Dam, G., Keiding, S., Munk, O. L., Ott, P., Vilstrup, H., Bak, Lasse Kristoffer, Waagepetersen, Helle S., Schousboe, Arne & Sørensen, M., Jan 2013, In: Hepatology. 57, 1, p. 258-65 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  95. Published

    Amino acid neurotransmitter synthesis and removal

    Schousboe, Arne, Bak, Lasse Kristoffer, Madsen, K. K. & Waagepetersen, Helle S., 2013, Neuroglia. Kettenman, H. & Ransom, B. R. (eds.). 3. ed. Oxford: Oxford University Press, p. 443-456 14 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  96. Published

    Discovery of a subtype-selective of the human betaine/GABA transporter 1 (BGT-1) with a non-competitive pharmacological profile

    Kragholm, B., Kvist, T., Madsen, K. K., Jørgensen, L., Vogensen, S. B., Schousboe, Arne, Clausen, Rasmus Prætorius, Jensen, Anders A. & Bräuner, Hans, 2013, In: Biochemical Pharmacology. 86, p. 521-528

    Research output: Contribution to journalJournal articleResearchpeer-review

  97. Published

    Glutamate neurotoxicity related to energy failure

    Schousboe, Arne, 2013, Handbook of neurotoxicity. Kostrzewa, R. (ed.). New York: Springer, p. 1299-1310 12 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  98. Published

    Impairment of short term memory in rats with hepatic encephalopathy due to bile duct ligation

    Leke, R., Oliveira, D., Forgiarini, L., Escobar, T., Hammes, T., Meyer, F., Silveira, T., Keiding, S. & Schousboe, Arne, 2013, In: Metabolic Brain Disease. 28, 2, p. 187-192 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  99. Published

    Interorgan metabolism of ornithine phenylacetate (OP)-A novel strategy for treatment of hyperammonemia

    Dadsetan, S., Sørensen, M., Bak, Lasse Kristoffer, Vilstrup, H., Ott, P., Schousboe, Arne, Jalan, R., Keiding, S. & Waagepetersen, Helle S., 2013, In: Biochemical Pharmacology. 85, 1, p. 115-23 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  100. Published

    Reply to letter to the editor by Zheng G et al. Venous blood ammonia can be associated with cerebral blood flow in hepatic encephalopathy

    Dam, G., Keiding, S., Munk, O. L., Ott, P., Vilstrup, H., Bak, Lasse Kristoffer, Waagepetersen, Helle S., Schousboe, Arne & Sørensen, M., 2013, In: Hepatology. 58, 2, p. 833-834

    Research output: Contribution to journalComment/debateResearchpeer-review

  101. 2012
  102. Published

    Energy Metabolism of the Brain

    McKenna, M. C., Dienel, G. A., Sonnewald, U., Waagepetersen, Helle S. & Schousboe, Arne, 1 Dec 2012, Basic Neurochemistry. Elsevier, p. 200-231 32 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  103. Published

    Procedure for calculation of potency and efficacy for ligands acting on Gs- and Gi-coupled receptors

    Meier, E., Schousboe, Arne & Belhage, B., Dec 2012, In: Neurochemical Research. 37, 12, p. 2767-2775 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  104. Published

    Primary cultures of astrocytes: their value in understanding astrocytes in health and disease

    Lange, S. C., Bak, Lasse Kristoffer, Waagepetersen, Helle S., Schousboe, Arne & Norenberg, M. D., Nov 2012, In: Neurochemical Research. 37, 11, p. 2569-88 20 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  105. Published

    Brain glycogen: new perspectives on its metabolic function and regulation at the subcellular level

    Obel, L. L. F., Müller, M. S., Walls, Anne Byriel, Sickmann, H. M., Bak, Lasse Kristoffer, Waagepetersen, Helle S. & Schousboe, Arne, 2 Mar 2012, In: Frontiers in Neuroenergetics. 4, 15 p.

    Research output: Contribution to journalReviewResearchpeer-review

  106. Published

    (1S, 3S)-3-amino-4-difluoromethylenyl-1-cyclopentanoic acid (CPP-115), a potent gamma-aminobutyric acid aminotransferase inactivator for the treatment of cocaine addiction

    Pan, Y., Gerasimov, M. R., Kvist, T., Wellendorph, Petrine, Madsen, K. K., Pera, E., Lee, H., Schousboe, Arne, Chebib, M., Bräuner, Hans, Craft, C. M., Brodie, J. D., Schiffer, W. K., Dewey, S. L., Miller, S. R. & Silverman, R. B., 1 Jan 2012, In: Journal of Medicinal Chemistry. 55, 1, p. 357-366

    Research output: Contribution to journalJournal articleResearchpeer-review

  107. Published

    Aspects of astrocyte energy metabolism, amino acid neurotransmitter homoeostasis and metabolic compartmentation

    Kreft, M., Bak, Lasse Kristoffer, Waagepetersen, Helle S. & Schousboe, Arne, 2012, In: A S N Neuro. 4, 3, p. 187 199 p.

    Research output: Contribution to journalReviewResearchpeer-review

  108. Published

    Brain energy and ammonia metabolism

    Bak, Lasse Kristoffer, Schousboe, Arne & Waagepetersen, Helle S., 2012, Functional molecular imaging in hepatology. Bentham Science Publishers, Vol. 1. p. 129-144 16 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  109. Published

    Brain glycogen and its role in supporting glutamate and GABA homeostasis in a type 2 diabetes rat model

    Sickmann, H. M., Waagepetersen, Helle S., Schousboe, Arne, Benie, A. J. & Bouman, S. D., 2012, In: Neurochemistry International. 60, 3, p. 267-75 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  110. Published

    Direct measurement of backflux between oxaloacetate and fumarate following pyruvate carboxylation

    Brekke, E., Walls, Anne Byriel, Nørfeldt, L., Schousboe, Arne, Waagepetersen, Helle S. & Sonnewald, U., 2012, In: Glia. 60, 1, p. 147-58 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  111. Published
  112. Published

    Glial cells in (patho)physiology

    Parpura, V., Heneka, M. T., Montana, V., Oliet, S. H. R., Schousboe, Arne, Haydon, P. G., Stout Jr., R. F., Spray, D. C., Andreas, R., Pannicke, T., Pekny, M., Pekna, M., Zorec, R. & Verkhratsky, A., 2012, In: Journal of Neurochemistry. 121, 1, p. 4-27 24 p.

    Research output: Contribution to journalReviewResearchpeer-review

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