Blanca Aldana

Blanca Aldana

Associate Professor


  1. 2023
  2. Published

    Alteration of microglial metabolism and inflammatory profile contributes to neurotoxicity in a hiPSC-derived microglia model of frontotemporal dementia 3

    Haukedal, H., Syshøj Lorenzen, S., Westi, Emil Winther, Corsi, G., Gadekar, V. P., McQuade, A., Davtyan, H., Doncheva, Nadezhda Tsankova, Schmid, B., Chandrasekaran, Abinaya, Seemann, Ernst Stefan, Cirera, Susanna, Blurton-Jones, M., Meyer, M., Gorodkin, Jan, Aldana, Blanca & Freude, Kristine, 2023, In: Brain, Behavior, and Immunity. 113, p. 353-373

    Research output: Contribution to journalJournal articlepeer-review

  3. Published

    Decanoic Acid Rescues Differences in AMPA-Mediated Calcium Rises in Hippocampal CA1 Astrocytes and Neurons in the 5xFAD Mouse Model of Alzheimer's Disease

    Abghari, M., Vu, J. T. C. M., Eckberg, N., Aldana, Blanca & Kohlmeier, Kristi Anne, 2023, In: Biomolecules. 13, 10, 25 p., 1461.

    Research output: Contribution to journalJournal articlepeer-review

  4. Accepted/In press
  5. E-pub ahead of print

    Fibroblast-Derived Lysyl Oxidase Increases Oxidative Phosphorylation and Stemness in Cholangiocarcinoma

    Lewinska, M., Zhuravleva, E., Satriano, L., Martinez, M. B., Bhatt, D. K., Oliveira, D. V. N. P., Antoku, Y., Keggenhoff, F. L., Castven, D., Marquardt, J. U., Matter, M. S., Erler, J. T., Oliveira, R. C., Aldana, B. I., Al-Abdulla, R., Perugorria, M. J., Calvisi, D. F., Perez, L. A., Rodrigues, P. M., Labiano, I. & 2 others, Banales, J. M. & Andersen, Jesper Bøje, 2023, (E-pub ahead of print) In: Gastroenterology.

    Research output: Contribution to journalJournal articlepeer-review

  6. Published

    Golgi fragmentation: One of the earliest organelle phenotypes in Alzheimer's disease neurons

    Haukedal, H., Corsi, G. I., Gadekar, V. P., Doncheva, N. T., Kedia, S., de Haan, N., Chandrasekaran, A., Jensen, P., Schiønning, P., Vallin, S., Marlet, F. R., Poon, A., Pires, C., Agha, F. K., Wandall, H. H., Cirera, S., Simonsen, A. H., Nielsen, T. T., Nielsen, J. E., Hyttel, P. & 7 others, Muddashetty, R., Aldana, Blanca, Gorodkin, Jan, Nair, D., Meyer, M., Larsen, M. R. & Freude, Kristine, 2023, In: Frontiers in Neuroscience. 17, 17 p., 1120086.

    Research output: Contribution to journalJournal articlepeer-review

  7. E-pub ahead of print

    Increased glucose metabolism and impaired glutamate transport in human astrocytes are potential early triggers of abnormal extracellular glutamate accumulation in hiPSC-derived models of Alzheimer's disease

    Salcedo, C., Pozo Garcia, V., Garcia-Adan, B., Ameen, Aisha, Gegelashvili, G., Waagepetersen, Helle S., Freude, Kristine & Aldana, Blanca, 2023, (E-pub ahead of print) In: Journal of Neurochemistry.

    Research output: Contribution to journalJournal articlepeer-review

  8. Published

    MicroRNA-27a-3p targets FoxO signalling to induce tumour-like phenotypes in bile duct cells

    Duwe, Lea, Munoz-Garrido, P., Lewinska, Monika, Lafuente Barquero, Juan Francisco, Satriano, L., Høgdall, Dan Taksony Solyom, Taranta, A., Nielsen, B. S., Ghazal, A., Matter, M. S., Banales, J. M., Aldana, Blanca, Gao, Y., Marquardt, J. U., Roberts, L. R., Oliveira, R. C., Koshiol, J., O'Rourke, Colm & Andersen, Jesper Bøje, 2023, In: Journal of Hepatology. 78, 13 p.

    Research output: Contribution to journalJournal articlepeer-review

  9. Published

    Potential Retinal Biomarkers in Alzheimer's Disease

    Garcia Bermudez, Mariana Yolotzin, Vohra, Rupali, Freude, Kristine, van Wijngaarden, P., Martin, K. K., Thomsen, M. S., Aldana, Blanca & Kolko, Miriam, 2023, In: International Journal of Molecular Sciences (Online). 24, 21, 26 p., 15834.

    Research output: Contribution to journalReviewpeer-review

  10. Published

    Preserved blood-brain barrier and neurovascular coupling in female 5xFAD model of Alzheimer's disease

    Zhukov, Oleg, He, Chen, Soylu-Kucharz, R., Cai, Changsi, Lauritzen, Andreas, Aldana, Blanca, Björkqvist, M., Lauritzen, Martin & Kucharz, Krzysztof, 2023, In: Frontiers in Aging Neuroscience. 15, 18 p., 1089005.

    Research output: Contribution to journalJournal articlepeer-review

  11. Published

    The Alzheimer's disease 5xFAD mouse model is best suited to investigate pretargeted imaging approaches beyond the blood-brain barrier

    Lopes van den Broek, S. I., Sehlin, D., Andersen, Jens Velde, Aldana, Blanca, Beschorner, Natalie, Nedergaard, Maiken, Knudsen, Gitte Moos, Syvanen, S. & Herth, Matthias Manfred, 2023, In: Frontiers in Nuclear Medicine. 2, 7 p., 1001722.

    Research output: Contribution to journalJournal articlepeer-review

  12. Published

    Using stable isotope tracing to unravel the metabolic components of neurodegeneration: Focus on neuron-glia metabolic interactions

    Westi, Emil Winther, Andersen, Jens Velde & Aldana, Blanca, 2023, In: Neurobiology of Disease. 182, 12 p., 106145.

    Research output: Contribution to journalJournal articlepeer-review

  13. Published

    β-Hydroxybutyrate and Medium-Chain Fatty Acids are Metabolized by Different Cell Types in Mouse Cerebral Cortex Slices

    Andersen, Jens Velde, Westi, Emil Winther, Neal, E. S., Aldana, Blanca & Borges, K., 2023, In: Neurochemical Research. 48, p. 54–61

    Research output: Contribution to journalComment/debatepeer-review

  14. 2022
  15. Published

    Decreased Glucose Metabolism and Glutamine Synthesis in the Retina of a Transgenic Mouse Model of Alzheimer's Disease

    Tams, A. L. M., Sanz-Morello, B., Westi, Emil Winther, Mouhammad, Zaynab Ahmad, Andersen, Jens Velde, Freude, Kristine, Vohra, Rupali, Hannibal, Jens, Aldana, Blanca & Kolko, Miriam, 2022, In: Cellular and Molecular Neurobiology. 42, 1, p. 291–303

    Research output: Contribution to journalJournal articlepeer-review

  16. Published

    Divergent Cellular Energetics, Glutamate Metabolism, and Mitochondrial Function Between Human and Mouse Cerebral Cortex

    Westi, Emil Winther, Jakobsen, Emil, Voss, C. M., Bak, Lasse Kristoffer, Pinborg, Lars Hageman, Aldana, Blanca & Andersen, J. V., 2022, In: Molecular Neurobiology. 59, p. 7495–7512

    Research output: Contribution to journalJournal articlepeer-review

  17. Published

    Fats, Friends or Foes: Investigating the Role of Short- and Medium-Chain Fatty Acids in Alzheimer’s Disease

    Ameen, Aisha, Freude, Kristine & Aldana, Blanca, 2022, In: Biomedicines. 10, 11, 2778.

    Research output: Contribution to journalJournal articlepeer-review

  18. Published

    Prevention of Cell Death by Activation of Hydroxycarboxylic Acid Receptor 1 (GPR81) in Retinal Explants

    Vohra, Rupali, Sanz-Morello, B., Tams, A. L. M., Mouhammad, Zaynab Ahmad, Freude, Kristine, Hannibal, Jens, Aldana, Blanca, Bergersen, L. H. & Kolko, Miriam, 2022, In: Cells. 11, 13, 2098.

    Research output: Contribution to journalJournal articlepeer-review

  19. Published

    Proteomic phenotype of cerebral organoids derived from autism spectrum disorder patients reveal disrupted energy metabolism, cellular components, and biological processes

    Ilieva, M., Aldana, Blanca, Vinten, K. T., Hohmann, S., Woofenden, T. W., Lukjanska, R., Waagepetersen, Helle S. & Michel, T. M., 2022, In: Molecular Psychiatry. 27, p. 3749–3759

    Research output: Contribution to journalJournal articlepeer-review

  20. 2021
  21. Published

    Amino acids: Glutamate dehydrogenase: An anaplerotic enzyme in neurons and an energy producing enzyme in astrocytes

    Schousboe, Arne & Aldana, Blanca, 29 Jul 2021, Encyclopedia of Biological Chemistry: Third Edition. Elsevier, Vol. 1. p. 51-55 5 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  22. Published

    Astrocyte metabolism of the medium-chain fatty acids octanoic acid and decanoic acid promotes GABA synthesis in neurons via elevated glutamine supply

    Andersen, Jens Velde, Westi, Emil Winther, Jakobsen, Emil, Urruticoechea, N., Borges, K. & Aldana, Blanca, 2021, In: Molecular Brain. 14, 1, 13 p., 132.

    Research output: Contribution to journalJournal articlepeer-review

  23. Published

    Astrocytic reactivity triggered by defective autophagy and metabolic failure causes neurotoxicity in frontotemporal dementia type 3

    Chandrasekaran, A., Dittlau, K. S., Corsi, G. I., Haukedal, H., Doncheva, N. T., Ramakrishna, S., Ambardar, S., Salcedo, C., Schmidt, S. I., Zhang, Y., Cirera, S., Pihl, M., Schmid, B., Nielsen, T. T., Nielsen, J. E., Kolko, M., Kobolák, J., Dinnyés, A., Hyttel, P., Palakodeti, D. & 5 others, Gorodkin, Jan, Muddashetty, R. S., Meyer, M., Aldana, Blanca & Freude, Kristine, 2021, In: Stem Cell Reports. 16, 11, p. 2736-2751

    Research output: Contribution to journalJournal articlepeer-review

  24. Published

    Brain endothelial cells metabolize glutamate via glutamate dehydrogenase to replenish TCA-intermediates and produce ATP under hypoglycemic conditions

    Hinca, S. B., Salcedo, C., Wagner, A., Goldeman, C., Sadat, E., Aibar, M. M. D., Maechler, P., Larsen, Birger Brodin, Aldana, Blanca & Helms, H. C. C., 2021, In: Journal of Neurochemistry. 157, 6, p. 1861-1875

    Research output: Contribution to journalJournal articlepeer-review

  25. Published

    Cellular bioenergetics in human iPSC-derived glutamatergic neurons in health and disease

    Aldana, Blanca, Salcedo, C., Freude, Kristine & Waagepetersen, Helle S., 2021, Current Progress in iPSC-derived Cell Types. Birbrair, A. (ed.). Elsevier, p. 205-221 17 p. (Advances in Stem Cell Biology, Vol. 10).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  26. Published

    Deficient astrocyte metabolism impairs glutamine synthesis and neurotransmitter homeostasis in a mouse model of Alzheimer's disease

    Andersen, Jens Velde, Christensen, S. K., Westi, Emil Winther, Diaz-delcastillo, M., Tanila, H., Schousboe, Arne, Aldana, Blanca & Waagepetersen, Helle S., 2021, In: Neurobiology of Disease. 148, 13 p., 105198.

    Research output: Contribution to journalJournal articlepeer-review

  27. Published

    Downregulation of GABA Transporter 3 (GAT3) is Associated with Deficient Oxidative GABA Metabolism in Human Induced Pluripotent Stem Cell-Derived Astrocytes in Alzheimer's Disease

    Salcedo, C., Wagner, A., Andersen, Jens Velde, Vinten, K. T., Waagepetersen, Helle S., Schousboe, Arne, Freude, Kristine & Aldana, Blanca, 2021, In: Neurochemical Research. 46, p. 2676–2686

    Research output: Contribution to journalJournal articlepeer-review

  28. Published
  29. Published

    Glutamate metabolism and recycling at the excitatory synapse in health and neurodegeneration

    Andersen, Jens Velde, Markussen, K. H., Jakobsen, Emil, Schousboe, Arne, Waagepetersen, Helle S., Rosenberg, P. A. & Aldana, Blanca, 2021, In: Neuropharmacology. 196, 14 p., 108719.

    Research output: Contribution to journalReviewpeer-review

  30. Published

    Hippocampal disruptions of synaptic and astrocyte metabolism are primary events of early amyloid pathology in the 5xFAD mouse model of Alzheimer's disease

    Andersen, Jens Velde, Skotte, Niels Henning, Christensen, S. K., Polli, F. S., Shabani, M., Markussen, K. H., Haukedal, H., Westi, Emil Winther, Diaz-delCastillo, M., Sun, R. C., Kohlmeier, Kristi Anne, Schousboe, Arne, Gentry, M. S., Tanila, H., Freude, Kristine, Aldana, Blanca, Mann, Matthias & Waagepetersen, Helle S., 2021, In: Cell Death & Disease. 12, 11, 13 p., 954 .

    Research output: Contribution to journalJournal articlepeer-review

  31. Published

    Inhibition of Glutamate Release, but Not of Glutamine Recycling to Glutamate, Is Involved in Delaying the Onset of Initial Lithium-Pilocarpine-Induced Seizures in Young Rats by a Non-Convulsive MSO Dose

    Pawlik, M. J., Aldana, Blanca, Belfiori-Carrasco, L. F., Obara-Michlewska, M., Popek, M. P., Czarnecka, A. M. & Albrecht, J., 2021, In: International Journal of Molecular Sciences. 22, 20, 16 p., 11127.

    Research output: Contribution to journalJournal articlepeer-review

  32. Published

    Neuronal Loss of the Glutamate Transporter GLT-1 Promotes Excitotoxic Injury in the Hippocampus

    Rimmele, T. S., Li, S., Andersen, Jens Velde, Westi, Emil Winther, Rotenberg, A., Wang, J., Aldana, Blanca, Selkoe, D. J., Aoki, C. J., Dulla, C. G. & Rosenberg, P. A., 2021, In: Frontiers in Cellular Neuroscience. 15, 788262.

    Research output: Contribution to journalJournal articlepeer-review

  33. Published

    Pharmacological inhibition of mitochondrial soluble adenylyl cyclase in astrocytes causes activation of AMP-activated protein kinase and induces breakdown of glycogen

    Jakobsen, Emil, Andersen, Jens Velde, Christensen, S. K., Siamka, O., Larsen, M. R., Waagepetersen, Helle S., Aldana, Blanca & Bak, Lasse Kristoffer, 2021, In: Glia. 69, 12, p. 2828-2844 17 p.

    Research output: Contribution to journalJournal articlepeer-review

  34. 2020
  35. Published

    Patient iPSC-Derived Neorons for Disease Modeling of Familiar Alzheimer's Disease with Mutations in Presenilin 1

    Haukedal, H., Poon, A. F., Jensen, P., Aldana, Blanca, Pires, C., Chandrasekaran, Abinaya, Christensen, S. K., Schiønning, P., Vallin, S., Simonsen, A. H., Nielsen, J., Dinnyes, A., Gorodkin, Jan, Ramakrishna, S., Muddashetty, R., Palakodeti, D., Hyttel, P., Waagepetersen, Helle S., Larsen, M. R. & Freude, Kristine, Oct 2020.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  36. Published

    Staphylococcus aureus induces cell-surface expression of immune stimulatory NKG2D ligands on human monocytes

    Mellergaard, M., Høgh, R. I., Feilberg, Astrid Lund, Aldana, Blanca, Guérillot, R., Møller, S. H., Hayes, A. S., Panagiotopoulou, N., Frimand, Z., Jepsen, Stine Dam, Hansen, Camilla Hartmann Friis, Andresen, Lars, Larsen, A. R., Peleg, A. Y., Stinear, T. P., Howden, B. P., Waagepetersen, Helle S., Frees, Dorte & Skov, Søren, 2020, In: The Journal of Biological Chemistry. 295, p. 11803-11821

    Research output: Contribution to journalJournal articlepeer-review

  37. Published

    Complex IV subunit isoform COX6A2 protects fast-spiking interneurons from oxidative stress and supports their function

    Sanz-Morello, B., Pfisterer, U., Hansen, Nikolaj Winther, Demharter, S., Thakur, A., Fujii, K., Levitskii, S. A., Montalant, Alexia, Korshunova, Irina, Mammen, P. P., Kamenski, P., Noguchi, S., Aldana, Blanca, Hougaard, K. S., Perrier, Jean-Francois Marie & Khodosevich, Konstantin, 2020, In: The EMBO Journal. 39, 18, p. 1-21 e105759.

    Research output: Contribution to journalJournal articlepeer-review

  38. Published

    Conditional Knockout of GLT-1 in Neurons Leads to Alterations in Aspartate Homeostasis and Synaptic Mitochondrial Metabolism in Striatum and Hippocampus

    McNair, Laura M., Andersen, Jens Velde, Nissen, J. D., Sun, Y., Fischer, K. D., Hodgson, N. W., Du, M., Aoki, C. J., Waagepetersen, Helle S., Rosenberg, P. A. & Aldana, Blanca, 2020, In: Neurochemical Research. 45, p. 1420–1437 18 p.

    Research output: Contribution to journalJournal articlepeer-review

  39. Published

    Conjugation of Therapeutic PSD-95 Inhibitors to the Cell-Penetrating Peptide Tat Affects Blood-Brain Barrier Adherence, Uptake, and Permeation

    Kristensen, Mie, Kucharz, Krzysztof, Alves Fernandes, Eduardo Felipe, Strømgaard, Kristian, Schallburg Nielsen, M., Cederberg Helms, H. C., Bach, Anders, Ulrikkaholm Tofte-Hansen, M., Aldana, Blanca, Lauritzen, Martin & Larsen, Birger Brodin, 2020, In: Pharmaceutics. 12, 7, 24 p., 661.

    Research output: Contribution to journalJournal articlepeer-review

  40. Published

    Cytoplasmic Citrate Flux Modulates the Immune Stimulatory NKG2D Ligand MICA in Cancer Cells

    Møller, S. H., Mellergaard, M., Madsen, M., Bermejo, A. V., Jepsen, Stine Dam, Hansen, M. H., Høgh, R. I., Aldana, Blanca, Desler, Claus, Rasmussen, Lene Juel, Sustarsic, E. G., Gerhart-Hines, Zach, Daskalaki, E., Wheelock, C. E., Hiron, T. K., Lin, D., O'Callaghan, C. A., Wandall, Hans H., Andresen, Lars & Skov, Søren, 2020, In: Frontiers in Immunology. 11, 22 p., 1968.

    Research output: Contribution to journalJournal articlepeer-review

  41. Published
  42. Published

    Glutamate-glutamine homeostasis is perturbed in neurons and astrocytes derived from patient iPSC models of frontotemporal dementia

    Aldana, Blanca, Zhang, Y., Jensen, P., Chandrasekaran, Abinaya, Christensen, S. K., Nielsen, T. T., Nielsen, Jørgen Erik, Hyttel, P., Larsen, M. R., Waagepetersen, Helle S. & Freude, Kristine, 2020, In: Molecular Brain. 13, 1, 7 p., 125.

    Research output: Contribution to journalJournal articlepeer-review

  43. Published

    Mutation in FTD3 CHMP2B causes impaired autography and distorted energy metabolism cumulating in reactive astrocyte phenotypes

    Chandrasekaran, A., Dittlau, K. S., Corsi, G., Haukedal, H., Doncheva, N. T., Ramakrishna, S., Ambardar, S., Salcedo, C., Schmidt, S. I., Cirera, S., Pihl, M., Schmid, B., Nielsen, T. T., Nielsen, J., Kolko, M., Kobolak, J., Dinnyes, A., Hyttel, P., Palakodeti, D., Gorodkin, J. & 4 others, Muddashetty, R., Meyer, M., Aldana, Blanca & Freude, Kristine, 2020.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  44. Published

    Mutations in FTD3 CHMP2B causes impaired autophagy and distorted energy metabolism cumulating in reactive astrocyte phenotypes

    Chandrasekaran, A., Dittlau, K. S., Corsi, G., Doncheva, N. T., Haukedal, H., Ramakrishna, S., Ambardar, S., Salcedo, C., Schmidt, S. I., Cirera, S., Pihl, M., Schmid, B., Nielsen, T. T., Nielsen, J., Kolko, M., Kobolak, J., Dinnyes, A., Hyttel, P., Palakodeti, D., Gorodkin, J. & 4 others, Muddashetty, R., Meyer, M., Aldana, Blanca & Freude, Kristine, 2020.

    Research output: Contribution to conferencePosterResearch

  45. 2019
  46. Published

    Lactate-Mediated Protection of Retinal Ganglion Cells

    Vohra, Rupali, Aldana, Blanca, Bulli, G., Jensen, Dorte Skytt, Waagepetersen, Helle S., Bergersen, L. H. & Kolko, Miriam, 19 Apr 2019, In: Journal of Molecular Biology. 431, 9, p. 1878-1888 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  47. Published

    Microglia-Specific Metabolic Changes in Neurodegeneration

    Aldana, Blanca, 19 Apr 2019, In: Journal of Molecular Biology. 431, 9, p. 1830-1842

    Research output: Contribution to journalReviewpeer-review

  48. Published

    Patient iPSC-Derived Neurons for Disease Modeling of Familiar Alzheier's Disease with Mutations in Presenilin 1

    Haukedal, H., Poon, A. F., Jensen, P., Aldana, Blanca, Pires, C., Chandrasekaran, Abinaya, Christensen, S. K., Schiønning, P., Vallin, S., Simonsen, A. H., Nielsen, J., Dinnyes, A., Gorodkin, Jan, Ramakrishna, S., Muddashetty, R., Palakodeti, D., Hyttel, P., Waagepetersen, Helle S., Larsen, M. R. & Freude, Kristine, 26 Mar 2019.

    Research output: Contribution to conferencePosterCommunication

  49. Published

    Dual Properties of Lactate in Müller Cells: The Effect of GPR81 Activation

    Vohra, Rupali, Aldana, Blanca, Waagepetersen, Helle S., Bergersen, L. H. & Kolko, Miriam, 1 Mar 2019, In: Investigative Ophthalmology & Visual Science. 60, 4, p. 999-1008 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  50. Published

    Deletion of neuronal GLT-1 in mice reveals its role in synaptic glutamate homeostasis and mitochondrial function

    McNair, Laura M., Andersen, Jens Velde, Aldana, Blanca, Hohnholt, M. C., Nissen, J. D., Sun, Y., Fischer, K. D., Sonnewald, U., Nyberg, N., Webster, S. C., Kapur, K., Rimmele, T. S., Barone, I., Hawks-Mayer, H., Lipton, J. O., Hodgson, N. W., Aoki, C. J., Rosenberg, P. A. & Waagepetersen, Helle S., 2019, In: The Journal of neuroscience : the official journal of the Society for Neuroscience. 39, 25, p. 4847-4863

    Research output: Contribution to journalJournal articlepeer-review

  51. Published

    Distinct differences in rates of oxygen consumption and ATP synthesis of regionally isolated non-synaptic mouse brain mitochondria

    Andersen, Jens Velde, Jakobsen, Emil, Waagepetersen, Helle S. & Aldana, Blanca, 2019, In: Journal of Neuroscience Research. 97, p. 961–974

    Research output: Contribution to journalJournal articlepeer-review

  52. Published

    Enhanced cerebral branched-chain amino acid metabolism in R6/2 mouse model of Huntington's disease

    Andersen, Jens Velde, Skotte, Niels Henning, Aldana, Blanca, Nørremølle, Anne & Waagepetersen, Helle S., 2019, In: Cellular and Molecular Life Sciences. 76, 12, p. 2449-2461

    Research output: Contribution to journalJournal articlepeer-review

  53. Published

    Generation of a set of isogenic, gene-edited iPSC lines homozygous for all main APOE variants and an APOE knock-out line

    Schmid, B., Prehn, K. R., Nimsanor, N., Aldana, Blanca, Poulsen, U., Jorring, I., Rasmussen, M. A., Clausen, C., Mau-Holzmann, U. A., Ramakrishna, S., Muddashetty, R., Steeg, R., Bruce, K., Mackintosh, P., Ebneth, A., Holst, B. & Cabrera-Socorro, A., 2019, In: Stem Cell Research. 34, 6 p., 101349.

    Research output: Contribution to journalEditorialpeer-review

  54. Published

    Glutamate homeostasis revisited - neuronal transport and metabolism

    Waagepetersen, Helle S., McNair, Laura M., Christensen, S. K., Andersen, Jens Velde & Aldana, Blanca, 2019, p. 19-19.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  55. 2018
  56. Published

    Essential Roles of Lactate in Müller Cell Survival and Function

    Vohra, Rupali, Aldana, Blanca, Jensen, Dorte Skytt, Freude, Kristine, Waagepetersen, Helle S., Bergersen, L. H. & Kolko, Miriam, 1 Dec 2018, In: Molecular Neurobiology. 55, 12, p. 9108-9121 14 p.

    Research output: Contribution to journalJournal articlepeer-review

  57. Published

    Muller cell survival and function is maintained by the presence of lactate

    Vohra, Rupali, Skytt, D. M., Aldana, Blanca, Freude, Kristine, Waagepetersen, Helle S., Bergersen, L. H. & Kolko, Miriam, Jul 2018, p. 1480. 1 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  58. Published

    Integrative Characterization of the R6/2 Mouse Model of Huntington's Disease Reveals Dysfunctional Astrocyte Metabolism

    Skotte, Niels Henning, Andersen, Jens Velde, Santos, A., Aldana, Blanca, Willert, C. W., Nørremølle, Anne, Waagepetersen, Helle S. & Nielsen, Michael Lund, 2018, In: Cell Reports. 23, 7, p. 2211-2224 14 p.

    Research output: Contribution to journalJournal articlepeer-review

  59. Published

    Lactate: More than merely a metabolic waste product

    Vohra, Rupali, Aldana, Blanca, Skytt, D. M., Waagepetersen, Helle S., Bergersen, L. H. & Kolko, Miriam, 2018, In: Acta Ophthalmologica. 96, Supplement 261, p. 137 1 p.

    Research output: Contribution to journalConference abstract in journalpeer-review

  60. Published

    Warburg Effect Metabolism Drives Neoplasia in a Drosophila Genetic Model of Epithelial Cancer

    Eichenlaub, T., Villadsen, René, Freitas, F. C. P., Andrejeva, Diana, Aldana, Blanca, Nguyen, H. T., Petersen, Ole William, Gorodkin, Jan, Herranz, Hector & Cohen, S. M., 2018, In: Current Biology. 28, 20, p. 3220-3228.e6

    Research output: Contribution to journalJournal articlepeer-review

  61. 2017
  62. Published

    The novel anticonvulsant neuropeptide and galanin analogue, NAX-5055, does not alter energy and amino acid metabolism in cultured brain cells

    Aldana, Blanca, Waagepetersen, Helle S., Schousboe, Arne, White, H. S., Bulaj, G. & Walls, Anne Byriel, Nov 2017, In: Journal of Neuroscience Research. 95, 11, p. 2286-2296 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  63. Published

    Alterations in Cerebral Cortical Glucose and Glutamine Metabolism Precedes Amyloid Plaques in the APPswe/PSEN1dE9 Mouse Model of Alzheimer's Disease

    Andersen, Jens Velde, Christensen, S. K., Aldana, Blanca, Nissen, J. D., Tanila, H. & Waagepetersen, Helle S., Jun 2017, In: Neurochemical Research. 42, 6, p. 1589–1598

    Research output: Contribution to journalJournal articlepeer-review

  64. Published
  65. Published

    Characterization of the L-glutamate clearance pathways across the blood-brain barrier and the effect of astrocytes in an in vitro blood-brain barrier model

    Helms, H. C., Aldana, Blanca, Groth, S., Jensen, M. M., Waagepetersen, Helle S., Nielsen, C. U. & Larsen, Birger Brodin, 2017, In: Journal of Cerebral Blood Flow and Metabolism. 37, 12, p. 3744–3758

    Research output: Contribution to journalJournal articlepeer-review

  66. Published

    Patient iPSC-derived neurons for disease modeling of frontotemporal dementia with mutation in CHMP2B

    Zhang, Y., Schmid, B., Qas Younan, N. K., Rasmussen, M. A., Garcia, B. I. A., Agger, M., Callø, K., Stummann, T. C., Larsen, H. M., Nielsen, T. T., Huang, J., Xu, F., Liu, X., Bolund, L., Meyer, M., Bak, L. K., Waagepetersen, H. S., Luo, Y., Nielsen, J. E., Consortium, T. FRA. & 4 others, Holst, B., Clausen, C., Hyttel, P. & Freude, Kristine, 2017, In: Stem Cell Reports. 8, 3, p. 648-658

    Research output: Contribution to journalJournal articlepeer-review

  67. 2016
  68. Published

    Effect of the Anti-depressant Sertraline, the Novel Anti-seizure Drug Vinpocetine and Several Conventional Antiepileptic Drugs on the Epileptiform EEG Activity Induced by 4-Aminopyridine

    Sitges, M., Aldana, Blanca & Reed, R. C., 1 Jun 2016, In: Neurochemical Research. 41, 6, p. 1365-1374 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  69. 2015
  70. Published

    Is there a relationship between sweet taste and seizures? Anticonvulsant and proconvulsant effects of non-nutritive sweeteners

    Di Ianni, M. E., Enrique, A. V., Del Valle, M. E., Aldana, Blanca, Rosella, M. A., Rocha, L., Castro, E. A., Bruno-Blanch, L. E. & Talevi, A., 2015, In: Combinatorial Chemistry and High Throughput Screening. 18, 4, p. 335-345 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  71. 2014
  72. Published

    Sertraline reduces IL-1β and TNF-α mRNA expression and overcomes their rise induced by seizures in the rat hippocampus

    Sitges, M., Gómez, C. D. & Aldana, Blanca, 3 Nov 2014, In: PLoS ONE. 9, 11, e111665.

    Research output: Contribution to journalJournal articlepeer-review

  73. Published

    Role of Histaminergic System in Blood-Brain Barrier Dysfunction Associated with Neurological Disorders

    Bañuelos-Cabrera, I., Valle-Dorado, M. G., Aldana, Blanca, Orozco-Suárez, S. A. & Rocha, L., 1 Nov 2014, In: Archives of Medical Research. 45, 8, p. 677-686 10 p.

    Research output: Contribution to journalReviewpeer-review

  74. 2012
  75. Published

    The antidepressant sertraline prevents the behavioral and EEG changes induced in two animal models of seizures

    Sitges, M., Aldana, Blanca, Gómez, C. D. & Nekrassov, V., Dec 2012, In: Epilepsy and Behavior. 25, 4, p. 511-516 6 p.

    Research output: Contribution to journalJournal articlepeer-review

  76. Published

    Sertraline inhibits pre-synaptic Na + channel-mediated responses in hippocampus-isolated nerve endings

    Aldana, Blanca & Sitges, M., Apr 2012, In: Journal of Neurochemistry. 121, 2, p. 197-205 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  77. 2011
  78. Published

    Vinpocetine inhibits glutamate release induced by the convulsive agent 4-aminopyridine more potently than several antiepileptic drugs

    Sitges, M., Sanchez-Tafolla, B. M., Chiu, L. M., Aldana, Blanca & Guarneros, A., Oct 2011, In: Epilepsy Research. 96, 3, p. 257-266 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  79. 2009
  80. Published

    Characterization of phenytoin, carbamazepine, vinpocetine and clorgyline simultaneous effects on sodium channels and catecholamine metabolism in rat striatal nerve endings

    Sitges, M., Aldana, Blanca, Chiu, L. M. & Nekrassov, V., Mar 2009, In: Neurochemical Research. 34, 3, p. 470-479 10 p.

    Research output: Contribution to journalJournal articlepeer-review

ID: 183889241