Christian Reinhard Otto Bartling

Christian Reinhard Otto Bartling

Assistant Professor


Publication year:
  1. 2018
  2. Published

    Probing the Mint2 Protein-Protein Interaction Network Relevant to the Pathophysiology of Alzheimer's Disease

    Jensen, T. M. T., Albertsen, L., Bartling, Christian Reinhard Otto, Haugaard-kedström, L. M. & Strømgaard, Kristian, 2018, In: ChemBioChem. 19, 11, p. 1119-1122 4 p.

    Research output: Contribution to journalJournal articlepeer-review

  3. Published

    Probing Backbone Hydrogen Bonds in Proteins by Amide-to-Ester Mutations

    Sereikaité, Vita, Jensen, T. M. T., Bartling, Christian Reinhard Otto, Jemth, P., Pless, Stephan & Strømgaard, Kristian, 18 Oct 2018, In: ChemBioChem. 19, 20, p. 2136-2145

    Research output: Contribution to journalReviewpeer-review

  4. 2020
  5. Published

    A high-affinity, bivalent PDZ domain inhibitor complexes PICK1 to alleviate neuropathic pain

    Christensen, N. R., De Luca, M., Lever, M. B., Richner, M., Hansen, A. B., Noes-Holt, G., Jensen, K. L., Rathje, M., Jensen, D. B., Erlendsson, S., Bartling, C. R. O., Ammendrup-Johnsen, I., Pedersen, S. E., Schönauer, M., Nissen, K. B., Midtgaard, S. R., Teilum, K., Arleth, L., Sørensen, A. T., Bach, A. & 5 others, Strømgaard, Kristian, Meehan, Claire Francesca, Vægter, C. B., Gether, Ulrik & Madsen, Kenneth Lindegaard, 2020, In: EMBO Molecular Medicine. 12, 6, 25 p., e11248.

    Research output: Contribution to journalJournal articlepeer-review

  6. 2021
  7. Published

    Molecular Details of a Coupled Binding and Folding Reaction between the Amyloid Precursor Protein and a Folded Domain

    Jensen, T. M. T., Bartling, Christian Reinhard Otto, Karlsson, O. A., Åberg, E., Haugaard-Kedström, L. M., Strømgaard, Kristian & Jemth, P., 2021, In: ACS chemical biology. 16, 7, p. 1191-1200

    Research output: Contribution to journalJournal articlepeer-review

  8. Published

    Site-specific phosphorylation of PSD-95 dynamically regulates the postsynaptic density as observed by phase separation

    Vistrup-Parry, M., Chen, X., Johansen, T. L., Bach, S., Buch-Larsen, Sara Charlotte, Bartling, Christian Reinhard Otto, Ma, C., Clemmensen, L. S., Nielsen, Michael Lund, Zhang, M. & Strømgaard, Kristian, 2021, In: iScience. 24, 11, 103268.

    Research output: Contribution to journalJournal articlepeer-review

  9. Published

    Targeting the APP-Mint2 Protein-Protein Interaction with a Peptide-Based Inhibitor Reduces Amyloid-β Formation

    Bartling, Christian Reinhard Otto, Jensen, T. M. T., Henry, S. M., Colliander, A. L., Sereikaité, Vita, Wenzler, M., Jain, P., Maric, H. M., Harpsøe, Kasper, Pedersen, S. W., Clemmensen, L. S., Haugaard-Kedström, L. M., Gloriam, David E., Ho, A. & Strømgaard, Kristian, 2021, In: Journal of the American Chemical Society. 143, 2, p. 891-901

    Research output: Contribution to journalJournal articlepeer-review

  10. 2022
  11. Published

    Aryl Fluorosulfate Based Inhibitors That Covalently Target the SIRT5 Lysine Deacylase**

    Bolding, J. E., Martín-Gago, P., Rajabi, N., Gamon, Luke Francis, Hansen, T. N., Bartling, Christian Reinhard Otto, Strømgaard, Kristian, Davies, Michael J. & Olsen, Christian Adam, 2022, In: Angewandte Chemie - International Edition. 61, 47, 11 p., e202204565.

    Research output: Contribution to journalJournal articlepeer-review

  12. Published

    Investigation of Carboxylic Acid Isosteres and Prodrugs for Inhibition of the Human SIRT5 Lysine Deacylase Enzyme**

    Rajabi, N., Hansen, T. N., Nielsen, A. L., Nguyen, H. T., Bæk, M., Bolding, J. E., Bahlke, O., Petersen, S. E. G., Bartling, Christian Reinhard Otto, Strømgaard, Kristian & Olsen, Christian Adam, 2022, In: Angewandte Chemie - International Edition. 61, 22, 9 p., e202115805.

    Research output: Contribution to journalJournal articlepeer-review

  13. 2023
  14. Published

    Comprehensive Peptide Cyclization Examination Yields Optimized APP Scaffolds with Improved Affinity toward Mint2

    Bartling, Christian Reinhard Otto, Alexopoulou, Flora, Kuschert, S., Chin, Y. K. Y., Jia, X., Sereikaité, Vita, Özcelik, D., Jensen, T. M., Jain, P., Nygaard, M. M., Harpsøe, Kasper, Gloriam, David E., Mobli, M. & Strømgaard, Kristian, 2023, In: Journal of Medicinal Chemistry. 66, 4, p. 3045-3057

    Research output: Contribution to journalJournal articlepeer-review

  15. Published

    Facilitating the structural characterisation of non-canonical amino acids in biomolecular NMR

    Kuschert, S., Stroet, M., Chin, Y. K. Y., Conibear, A. C., Jia, X., Lee, T., Bartling, Christian Reinhard Otto, Strømgaard, Kristian, Güntert, P., Rosengren, K. J., Mark, A. E. & Mobli, M., 2023, In: Magnetic Resonance. 4, 1, p. 57-72

    Research output: Contribution to journalJournal articlepeer-review

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