Dilip Narayanan

Dilip Narayanan

Assistant Professor


  1. 2023
  2. Published

    Small-molecule modulators of tumor necrosis factor signaling

    Chédotal, H., Narayanan, Dilip, Povlsen, K., Gotfredsen, C. H., Brambilla, R., Gajhede, Michael, Bach, Anders & Clausen, M. H., 2023, In: Drug Discovery Today. 28, 6, 103575.

    Research output: Contribution to journalReviewpeer-review

  3. Published

    Targeting NOX2 with Bivalent Small-Molecule p47phox-p22phox Inhibitors

    Zang, J., Peters, F., Cambet, Y., Cifuentes-Pagano, E., Hissabu, M. M. S., Dustin, C. M., Svensson, L. H., Olesen, M. M., Poulsen, M. F. L., Jacobsen, Stig, Tuelung, P. S., Narayanan, Dilip, Langkilde, Annette Eva, Gajhede, Michael, Pagano, P. J., Jaquet, V., Vilhardt, Frederik & Bach, Anders, 2023, In: Journal of Medicinal Chemistry. 66, 21, p. 14963–15005

    Research output: Contribution to journalJournal articlepeer-review

  4. 2022
  5. Published

    Development of Noncovalent Small-Molecule Keap1-Nrf2 Inhibitors by Fragment-Based Drug Discovery

    Narayanan, Dilip, Tran, K. T., Pallesen, J. S., Solbak, S. M. Ø., Qin, Y., Mukminova, E., Luchini, M., Vasilyeva, K. O., González Chichón, D., Goutsiou, G., Poulsen, C., Haapanen, N., Popowicz, G. M., Sattler, M., Olagnier, D., Gajhede, Michael & Bach, Anders, 2022, In: Journal of Medicinal Chemistry. 65, 21, p. 14481-14526

    Research output: Contribution to journalJournal articlepeer-review

  6. 2021
  7. Published

    Deconstructing Noncovalent Kelch-like ECH-Associated Protein 1 (Keap1) Inhibitors into Fragments to Reconstruct New Potent Compounds

    Pallesen, J. S., Narayanan, Dilip, Tran, K. T., Solbak, Sara Marie Øie, Marseglia, G., Sørensen, L. M. E., Høj, L. J., Munafò, F., Carmona, R. M. C., Garcia, A. D., Desu, H. L., Brambilla, R., Johansen, Tommy Nørskov, Popowicz, G. M., Sattler, M., Gajhede, Michael & Bach, Anders, 2021, In: Journal of Medicinal Chemistry. 64, 8, p. 4623–4661

    Research output: Contribution to journalJournal articlepeer-review

  8. 2020
  9. Published

    Developing Inhibitors of the p47phox-p22phox Protein-Protein Interaction by Fragment-Based Drug Discovery

    Solbak, Sara Marie Øie, Zang, J., Narayanan, Dilip, Høj, L. J., Bucciarelli, S., Softley, C., Meier, S., Langkilde, Annette Eva, Gotfredsen, C. H., Sattler, M. & Bach, Anders, 2020, In: Journal of Medicinal Chemistry. 63, 3, p. 1156-1177

    Research output: Contribution to journalJournal articlepeer-review

  10. Published

    Targeting the Redox Landscape in Cancer Therapy

    Narayanan, Dilip, Ma, S. & Özcelik, D., 2020, In: Cancers. 12, 7, 29 p., 1706.

    Research output: Contribution to journalReviewpeer-review

  11. 2019
  12. Published

    A Comparative Assessment Study of Known Small-Molecule Keap1-Nrf2 Protein-Protein Interaction Inhibitors: Chemical Synthesis, Binding Properties, and Cellular Activity

    Tran, K. T., Pallesen, J. S., Solbak, Sara Marie Øie, Narayanan, Dilip, Baig, A., Zang, J., Aguayo-Orozco, A., Carmona, R., Garcia, A. & Bach, Anders, 2019, In: Journal of Medicinal Chemistry. 62, 17, p. 8028-8052

    Research output: Contribution to journalJournal articlepeer-review

  13. 2017
  14. Published

    Data driven polypharmacological drug design for lung cancer: analyses for targeting ALK, MET, and EGFR

    Narayanan, Dilip, Gani, O. A., Gruber, F. X. & Engh, R. A., 2017, In: Journal of Cheminformatics. 9, 19 p., 43.

    Research output: Contribution to journalJournal articlepeer-review

  15. 2015
  16. Assessing protein kinase target similarity: Comparing sequence, structure, and cheminformatics approaches

    Gani, O. A., Thakkar, B., Narayanan, Dilip, Alam, K. A., Kyomuhendo, P., Rothweiler, U., Tello-Franco, V. & Engh, R. A., Oct 2015, In: Biochimica et biophysica acta. 1854, 10 Pt B, p. 1605-16 12 p.

    Research output: Contribution to journalJournal articlepeer-review

  17. 2013
  18. Published

    Evaluating the predictivity of virtual screening for ABL kinase inhibitors to hinder drug resistance

    Gani, O. A. B. S. M., Narayanan, Dilip & Engh, R. A., Nov 2013, In: Chemical Biology & Drug Design. 82, 5, p. 506-19 14 p.

    Research output: Contribution to journalJournal articlepeer-review

ID: 160904351