Flemming Steen Jørgensen

Flemming Steen Jørgensen

Professor


  1. 2017
  2. Published

    Mechanism of Cytochrome P450 17A1-Catalyzed Hydroxylase and Lyase Reactions

    Bonomo, S., Jørgensen, Flemming Steen & Olsen, L., 22 May 2017, In: Journal of Chemical Information and Modeling. 57, 5, p. 1123-1133 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  3. Published

    The low binding affinity of D-serine at the ionotropic glutamate receptor GluD2 can be attributed to the hinge region

    Tapken, D., Steffensen, T. B., Leth, R., Kristensen, L. B., Gerbola, A., Gajhede, Michael, Jørgensen, Flemming Steen, Olsen, L. & Kastrup, Jette Sandholm Jensen, 7 Apr 2017, In: Scientific Reports. 7, 12 p., 46145.

    Research output: Contribution to journalJournal articlepeer-review

  4. Published

    Structure-based optimisation of non-steroidal cytochrome P450 17A1 inhibitors

    Larsen, M., Hansen, C. H., Rasmussen, T. B., Styrishave, Bjarne, Olsen, L. & Jørgensen, Flemming Steen, 28 Feb 2017, In: Chemical Communications. 53, 3118, 4 p., 3118.

    Research output: Contribution to journalJournal articlepeer-review

  5. Published

    Dissecting the Cytochrome P450 1A2- and 3A4-Mediated Metabolism of Aflatoxin B1 in Ligand and Protein Contributions

    Bonomo, S., Jørgensen, Flemming Steen & Olsen, L., 24 Feb 2017, In: Chemistry: A European Journal. 23, 12, p. 2884-2893 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  6. 2016
  7. Published

    Promising Tools in Prostate Cancer Research: Selective Non-Steroidal Cytochrome P450 17A1 Inhibitors

    Bonomo, S., Hansen, C. H., Petrunak, E. M., Scott, E. E., Styrishave, Bjarne, Jørgensen, Flemming Steen & Olsen, L., 12 Jul 2016, In: Scientific Reports. 6, 11 p., 29468.

    Research output: Contribution to journalJournal articlepeer-review

  8. Published

    Enantioselective endocrine disrupting effects of omeprazole studied in the H295R cell assay and by molecular modeling

    Sørensen, A. M., Hansen, C. H., Bonomo, S., Olsen, L., Jørgensen, Flemming Steen, Weisser, J. J., Kretschmann, A. C. & Styrishave, Bjarne, 19 Mar 2016, In: Toxicology in Vitro. 34, p. 71-80 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  9. Published

    Insights into regioselective metabolism of mefenamic acid by cytochrome P450 BM3 mutants through crystallography, docking, molecular dynamics, and free energy calculations

    Capoferri, L., Leth, R., Ter Haar, E., Mohanty, A. K., Grootenhuis, P. D. J., Vottero, E., Commandeur, J. M. N., Vermeulen, N. P. E., Jørgensen, Flemming Steen, Olsen, L. & Geerke, D. P., Mar 2016, In: Proteins: Structure, Function, and Bioinformatics. 84, 3, p. 383-96 14 p.

    Research output: Contribution to journalJournal articlepeer-review

  10. Published

    Cytochrome P450 Mediated Drug Metabolism

    Olsen, L., Jørgensen, Flemming Steen & Oostenbrink, C., 2016, New Horizons in Predictive Drug Metabolism and Pharmacokinetics. Wilson, A. G. E. (ed.). Cambridge: Royal Society of Chemistry, p. 66-78 13 p. (RSC Drug Discovery, Vol. 49).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  11. 2015
  12. Published

    Prediction of cytochrome P450 mediated metabolism

    Olsen, L., Oostenbrink, C. & Jørgensen, Flemming Steen, 6 May 2015, In: Advanced Drug Delivery Reviews. 86, p. 61-71 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  13. Published

    Density functional theory study on the formation of reactive benzoquinone imines by hydrogen abstraction

    Leth, R., Rydberg, P., Jørgensen, Flemming Steen & Olsen, L., 23 Mar 2015, In: Journal of Chemical Information and Modeling. 55, 3, p. 660-6 7 p.

    Research output: Contribution to journalJournal articlepeer-review

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