Harald S. Hansen

Harald S. Hansen

Professor, emeritus

ORCID: 0000-0001-7360-7418

Publication year:
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  1. 2022
  2. Published

    Vagal afferent cholecystokinin receptor activation is required for glucagon-like peptide-1–induced satiation

    Vana, V., Lærke, M. K., Rehfeld, Jens Frederik, Arnold, M., Dmytriyeva, O., Langhans, W., Schwartz, Thue W. & Hansen, Harald S., 2022, In: Diabetes, Obesity and Metabolism. 24, 2, p. 268-280

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. 2021
  4. Published

    Post-oral fat-induced satiation is mediated by endogenous CCK and GLP-1 in a fat self-administration mouse model

    Vana, V., Lærke, M. K., Kleberg, K., Mroz, P. A., Lindberg, B. L., Ekberg, J. H., Rehfeld, Jens Frederik, Schwartz, Thue W. & Hansen, Harald S., 2021, In: Physiology and Behavior. 234, 12 p., 113315.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. 2020
  6. Published

    Data-enriched edible pharmaceuticals (DEEP) of medical cannabis by inkjet printing

    Öblom, H., Cornett, Claus, Bøtker, Johan Peter, Frøkjær, Sven, Hansen, Harald S., Rades, Thomas, Rantanen, Jukka & Genina, Natalja, 2020, In: International Journal of Pharmaceutics. 589, p. 1-11 119866.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Intestinal sensing and handling of dietary lipids in gastric bypass-operated patients and matched controls

    Martinussen, C., Dirksen, C., Bojsen-Møller, K. N., Svane, M. S., Carlsson, E. R., Hartmann, Bolette, Clausen, T. R., Veedfald, Simon, Kristiansen, V. B., Rehfeld, Jens Frederik, Hansen, Harald S., Holst, Jens Juul & Madsbad, Sten, 2020, In: American Journal of Clinical Nutrition. 111, 1, p. 28-41

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Intrapulmonary (i.pulmon.) Pull Immunization With the Tuberculosis Subunit Vaccine Candidate H56/CAF01 After Intramuscular (i.m.) Priming Elicits a Distinct Innate Myeloid Response and Activation of Antigen-Presenting Cells Than i.m. or i.pulmon. Prime Immunization Alone

    Thakur, A., Pinto, F. E., Hansen, Harald S., Andersen, Peter, Christensen, D., Janfelt, Christian & Foged, Camilla, 2020, In: Frontiers in Immunology. 11, p. 803

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    The autocrine role of FGF21 in cultured adipocytes

    Justesen, S., Haugegaard, K. V., Hansen, Jacob B., Hansen, Harald S. & Andersen, B., 2020, In: The Biochemical journal. 477, 13, p. 2477-2487 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. 2019
  11. Published

    Non-endocannabinoid N-acylethanolamines and 2-monoacylglycerols in the intestine

    Hansen, Harald S. & Vana, V., May 2019, In: British Journal of Pharmacology. 176, 10, p. 1443-1454

    Research output: Contribution to journal › Review › Research › peer-review

  12. Published

    Essentiality of n-6 fatty acids

    Hansen, Harald S., 26 Apr 2019, In: Journal of Biological Chemistry. 294, p. 6692 1 p.

    Research output: Contribution to journal › Journal article › Communication

  13. 2018
  14. Published

    Delivery of amitriptyline by intravenous and intraperitoneal administration compared in the same animal by whole-body mass spectrometry imaging of a stable isotope labelled drug substance in mice

    Morineau, L., Jacobsen, S. C., Kleberg, K., Hansen, Harald S. & Janfelt, Christian, 2 Dec 2018, In: Expert Opinion on Drug Delivery. 15, 12, p. 1157-1163

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Comparing olive oil and C4-dietary oil, a prodrug for the GPR119 agonist, 2-oleoyl glycerol, less energy intake of the latter is needed to stimulate incretin hormone secretion in overweight subjects with type 2 diabetes

    Mandøe, M. J., Hansen, K. B., Windeløv, Johanne Agerlin, Knop, Filip Krag, Rehfeld, Jens Frederik, Rosenkilde, Mette, Holst, Jens Juul & Hansen, Harald S., 2018, In: Nutrition and Diabetes. 8, 1, p. 1-10 2.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. 2017
  17. Published

    Gastric Bypass Surgery Recruits a Gut PPAR-α-Striatal D1R Pathway to Reduce Fat Appetite in Obese Rats

    Hankir, M. K., Seyfried, F., Hintschich, C. A., Diep, T., Kleberg, K., Kranz, M., Deuther-Conrad, W., Tellez, L. A., Rullmann, M., Patt, M., Teichert, J., Hesse, S., Sabri, O., Brust, P., Hansen, Harald S., de Araujo, I. E., Krügel, U. & Fenske, W. K., 7 Feb 2017, In: Cell Metabolism. 25, 2, p. 335-344 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. 2016
  19. Published

    Mass spectrometry imaging of biomarker lipids for phagocytosis and signalling during focal cerebral ischaemia

    Nielsen, M. M. B., Lambertsen, K. L., Clausen, B. H., Meyer, M., Bhandari, D. R., Larsen, S. T., Poulsen, Steen Seier, Spengler, B., Janfelt, Christian & Hansen, Harald S., 22 Dec 2016, In: Scientific Reports. 6, p. 1-14 14 p., 39571.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    GPR119 - a major Enteroendocrine Sensor of Dietary Triglyceride Metabolites Co-acting in Synergy with FFA1 (GPR40)

    Ekberg, J. H., Pedersen, M. H., Kristensen, L. V., Madsen, A. N., Engelstoft, M. S., Husted, Anna Sofie, Sichlau, R., Egerod, Kristoffer Lihme, Timshel, P., Kowalski, T. J., Gribble, F. M., Reiman, F., Hansen, Harald S., Howard, A. D., Holst, Birgitte & Schwartz, Thue W., 25 Oct 2016, In: Endocrinology. 157, 12, p. 4561-4569 9 p., en20161334.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Biased signaling of lipids and allosteric actions of synthetic molecules for GPR119

    Hassing, H. A., Fares, S., Larsen, Olav, Pad, H., Pedersen, M. H., Jones, R. M., Schwartz, Thue W., Hansen, Harald S. & Rosenkilde, Mette, 26 Aug 2016, In: Biochemical Pharmacology. 119, 1, p. 66-75 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Cryo-sectioning of mice for whole-body imaging of drugs and metabolites with desorption electrospray ionization mass spectrometry imaging - a simplified approach

    Okutan, S., Hansen, Harald S. & Janfelt, Christian, Jun 2016, In: Proteomics. 16, 11-12, p. 1633-41 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Opioid and cannabinoid receptors

    Clausen, Rasmus Prætorius & Hansen, Harald S., 2016, Textbook of drug design and discovery. 5. ed. CRC Press, p. 329-346

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Education

  24. Published

    Oral 2-oleyl glyceryl ether improves glucose tolerance in mice through the GPR119 receptor

    Hassing, H. A., Engelstoft, M. S., Sichlau, R. M., Madsen, A. N., Rehfeld, Jens Frederik, Pedersen, Jens, Jones, R. M., Holst, Jens Juul, Schwartz, Thue W., Rosenkilde, Mette & Hansen, Harald S., 2016, In: BioFactors. 42, 6, p. 665-673

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. 2015
  26. Published

    Sensing of triacylglycerol in the gut: different mechanisms for fatty acids and 2-monoacylglycerol

    Kleberg, K., Jacobsen, A. K., Ferreira, J. G., Windeløv, Johanne Agerlin, Rehfeld, Jens Frederik, Holst, Jens Juul, de Araujo, I. E. & Hansen, Harald S., 16 Jan 2015, In: The Journal of Physiology. 593, 8, p. 2097-109 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Fedtstoffer

    Dyerberg, J., Hansen, Harald S. & Stender, S., 2015, Menneskets Ernæring. Astrup, A., Bügel, S., Dyerberg, J. & Stender, S. (eds.). 4.udgave ed. København: Munksgaard , p. 99-117 19 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Education › peer-review

  28. Published

    Non-endocannabinoid N-Acylethanolamines and Monoacylglycerols: Old Molecules New Targets

    Hansen, Harald S., Kleberg, K. & Hassing, H. A., 2015, The Endocannabinoidome: The World of Endocannabinoids and Related Mediators. Di Marzo, V. & Wang, J. (eds.). Amsterdam, Vol. Elsevier. p. 1-13 13 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  29. Published

    The 2-monoacylglycerol moiety of dietary fat appears to be responsible for the fat-induced release of GLP-1 in humans.

    Mandøe, M. J., Hansen, K. B., Hartmann, Bolette, Rehfeld, Jens Frederik, Holst, Jens Juul & Hansen, Harald S., 2015, In: The American Journal of Clinical Nutrition. 102, 3, p. 548-555 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. 2014
  31. Published

    Evaluation of the immediate vascular stability of lipoprotein lipase-generated 2-monoacylglycerol in mice

    Kleberg, K., Nielsen, L. L., Stuhr-Hansen, N., Nielsen, J. & Hansen, Harald S., Nov 2014, In: BioFactors. 40, 6, p. 596-602 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    The PPARalpha agonist, fenofibrate decreases levels of anorectic N-acylethanolamines in the small intestine of mice

    Diep, T. A., Golbas, G. & Hansen, Harald S., 28 Jun 2014. 1 p.

    Research output: Contribution to conference › Conference abstract for conference › Research

  33. Published

    Role of anorectic N-acylethanolamines in intestinal physiology and satiety control with respect to dietary fat

    Hansen, Harald S., 28 Mar 2014, In: Pharmacological Research. 86, p. 18-25 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Classical endocannabinoid-like compounds and their regulation by nutrients

    Kleberg, K., Hassing, H. A. & Hansen, Harald S., 2014, In: BioFactors (Oxford, England). 40, 4, p. 363-372 10 p.

    Research output: Contribution to journal › Journal article › Research

  35. Published

    Dietary non-esterified oleic Acid decreases the jejunal levels of anorectic N-acylethanolamines

    Diep, T. A., Madsen, A. N., Krogh-Hansen, S., Al-Shahwani, M., Al-Sabagh, L., Holst, Birgitte & Hansen, Harald S., 2014, In: PloS one. 9, 6, p. 1-7 7 p., e100365.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. 2013
  37. Published

    Comment on: Harte et al. High Fat Intake Leads to Acute Postprandial Exposure to Circulating Endotoxin in Type 2 Diabetic Subjects. Diabetes Care 2012;35:375-382

    Hansen, Harald S., Moesby, L., Timm, M. & Hansen, E. W., Mar 2013, In: Diabetes Care. 36, 3, p. e42

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  38. Published

    Displaced dual-mode imaging with desorption electrospray ionization for simultaneous mass spectrometry imaging in both polarities and with several scan modes

    Janfelt, Christian, Wellner, N., Hansen, Harald S. & Hansen, S. H., Mar 2013, In: Journal of Mass Spectrometry. 48, 3, p. 361-6 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    N-acylation of phosphatidylethanolamine and its biological functions in mammals

    Wellner, N., Diep, T. A., Janfelt, Christian & Hansen, Harald S., Mar 2013, In: BBA General Subjects. 1831, 3, p. 652-62 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Effect of diet on tissue levels of palmitoylethanolamide

    Hansen, Harald S., 1 Feb 2013, In: C N S & Neurological Disorders - Drug Targets. 12, 1, p. 17-25 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. 2012
  42. Published

    Incretin hormones in patients with type 2 diabetes are increased by diet-oil, a pro-drug for the GPR 119 receptor agonist, 2-oleoyl-glycerol

    Mandoe, M. J., Hansen, K. B., Knop, Filip Krag, Holst, Jens Juul & Hansen, Harald S., Oct 2012, In: Diabetologia. 55, p. S340-S340

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  43. Published

    GPR119 as a fat sensor

    Hansen, Harald S., Rosenkilde, Mette, Holst, Jens Juul & Schwartz, Thue W., Jul 2012, In: Trends in Pharmacological Sciences. 33, 7, p. 374-81 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Ischemia in neonatal rat brains analyzed by Desorption Electrospray Ionization Imaging mass spectrometry

    Janfelt, Christian, Wellner, N., Leger, P., Kokesch-Himmelreich, J., Hansen, S. H., Charriaut-Marlangue, C. & Hansen, Harald S., 2012.

    Research output: Contribution to conference › Poster › Research › peer-review

  45. Published

    Metformin stimulates FGF21 expression in primary hepatocytes

    Nygaard, E. B., Vienberg, S. G., Ørskov, Cathrine, Hansen, Harald S. & Andersen, B., 2012, In: Experimental Diabetes Research. 2012, p. 465282 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Visualization by mass spectrometry of 2-dimensional changes in rat brain lipids, including N-acylphosphatidylethanolamines, during neonatal brain ischemia

    Janfelt, Christian, Wellner, N., Leger, P., Kokesch-Himmelreich, J., Hansen, S. H., Charriaut-Marlangue, C. & Hansen, Harald S., 2012, In: F A S E B Journal. 26, 6, p. 2667-2673

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. 2011
  48. Published

    Massespektrometri viser fordelingen af lægemiddelstoffer i planter og væv

    Janfelt, Christian, Thunig, J., Li, B., Andersen, N. W., Hansen, Harald S. & Hansen, S. H., Dec 2011, In: Lægemiddelforskning. 2011, p. 10-12

    Research output: Contribution to journal › Journal article › Communication

  49. Published

    Studies on the anorectic effect of N-acylphosphatidylethanolamine and phosphatidylethanolamine in mice

    Wellner, N., Tsuboi, K., Madsen, A. N., Holst, Birgitte, Diep, T. A., Nakao, M., Tokumura, A., Burns, M. P., Deutsch, D. G., Ueda, N. & Hansen, Harald S., 1 Sep 2011, In: BBA General Subjects. 1811, 9, p. 508-12 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    2-Oleoyl glycerol is a GPR119 agonist and signals GLP-1 release in humans

    Hansen, K. B., Rosenkilde, Mette, Knop, Filip Krag, Wellner, N., Diep, T. A., Rehfeld, Jens Frederik, Andersen, U. B., Holst, Jens Juul & Hansen, Harald S., 2011, In: Journal of Clinical Endocrinology and Metabolism. 96, 9, p. E1409-17

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    Dietary fat decreases intestinal levels of the anorectic lipids through a fat sensor

    Diep, T. A., Madsen, A. N., Holst, Birgitte, Kristiansen, M. M., Andersen, N. W., Hansen, S. H. & Hansen, Harald S., 2011, In: The FASEB Journal. 25, 2, p. 765-774

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    Investigations of the human endocannabinoid system in two subcutaneous adipose tissue depots in lean subjects and in obese subjects before and after weight loss

    Bennetzen, M. F., Wellner, N., Ahmed, S. S. U., Ahmed, S. M., Diep, T. A., Hansen, Harald S., Richelsen, B. & Pedersen, S. B., 2011, In: International Journal of Obesity. 35, 11, p. 1377-84 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  53. Published

    Locked nucleic acid antisense oligonucleotides in treatment of hypercholesterolemia

    Hansen, Harald S., 2011, København: Københavns Universitet. 84 p.

    Research output: Book/Report › Ph.D. thesis › Research

  54. 2010
  55. Published

    Treatment of insulin resistance and obesity by stimulating GLP-1 release

    Hansen, Harald S., Diep, T. A., Holst, Jens Juul, Rosenkilde, Mette & Andersen, N. W., 29 Dec 2010, IPC No. A61K 31/23, Patent No. PCT/DK2010/050161, 24 Jun 2010

    Research output: Patent

  56. Published

    International Union of Basic and Clinical Pharmacology. LXXIX. Cannabinoid receptors and their ligands: beyond CB1 and CB2

    Pertwee, R. G., Howlett, A. C., Abood, M. E., Alexander, S. P. H., Di Marzo, V., Elphick, M. R., Greasley, P. J., Hansen, Harald S., Kunos, G., Mackie, K., Mechoulam, R. & Ross, R. A., 1 Dec 2010, In: Pharmacological Reviews. 62, 4, p. 588-631 44 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  57. Published

    Long-term characterization of the diet-induced obese and diet-resistant rat model: a polygenetic rat model mimicking the human obesity syndrome

    Madsen, A. N., Hansen, G., Paulsen, S. J., Lykkegaard, K., Christensen, M. T., Hansen, Harald S., Levin, B. E., Larsen, P. J., Knudsen, L. B., Fosgerau, K. & Vrang, N., 1 Sep 2010, In: Journal of Endocrinology. 206, 3, p. 287-96 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  58. Published

    The endocannabinoid system and its relevance for nutrition

    Maccarrone, M., Gasperi, V., Catani, M. V., Diep, T. A., Dainese, E., Hansen, Harald S. & Avigliano, L., 21 Aug 2010, In: Annual Review of Nutrition. 30, p. 423-40 18 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  59. Published

    Palmitoylethanolamide and other anandamide congeners. Proposed role in the diseased brain

    Hansen, Harald S., 1 Jul 2010, In: Experimental Neurology. 224, 1, p. 48-55 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  60. Published

    Effect of the cannabinoid receptor-1 antagonist rimonabant on lipolysis in rats

    Mølhøj, S., Hansen, Harald S., Schweiger, M., Zimmermann, R., Johansen, T. & Malmlöf, K., 2010, In: European Journal of Pharmacology. 646, 1-3, p. 38-45

    Research output: Contribution to journal › Journal article › Research › peer-review

  61. Published

    Fedtstoffer

    Dyerberg, J., Hansen, Harald S. & Stender, S., 2010, Menneskets ernæring. Astrup, A., Bügel, S., Dyerberg, J. & Stender, S. (eds.). 3. udgave ed. København: Munksgaard , p. 93-109 17 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Education

  62. Published

    High fat diet influences N-acetylethanolamide formation in the intestine

    Diep, T. A., Kristiansen, M. M., Hansen, S. & Hansen, Harald S., 2010.

    Research output: Contribution to conference › Poster › Research

  63. Published

    Opioid and cannabinoid receptors

    Clausen, Rasmus Prætorius & Hansen, Harald S., 2010, Textbook of drug design and discovery. Krogsgaard-Larsen, P., Strømgaard, K. & Madsen, U. (eds.). 4 ed. Boca Raton: CRC Press, p. 313-328

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Education

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