Henrik Franzyk

Henrik Franzyk

Associate Professor

Member of:


    1. 2024
    2. E-pub ahead of print

      Lipid nanoparticles for local delivery of mRNA to the respiratory tract: Effect of PEG-lipid content and administration route

      Ongun, Melike, Lokras, Abhijeet, Baghel, Saahil Sandeep, Shi, Zhenning, Schmidt, S. T., Franzyk, Henrik, Rades, Thomas, Sebastiani, Federica, Thakur, A. & Foged, Camilla, 16 Mar 2024, (E-pub ahead of print) In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. p. 114266

      Research output: Contribution to journalJournal articlepeer-review

    3. Published

      Antimicrobial peptides grafted onto the surface of N-acetylcysteine-chitosan nanoparticles can revitalize drugs against clinical isolates of Mycobacterium tuberculosis

      Primo, L. M. D. G., Roque-Borda, C. A., Carnero Canales, C. S., Caruso, I. P., de Lourenço, I. O., Colturato, V. M. M., Sábio, R. M., de Melo, F. A., Vicente, E. F., Chorilli, M., da Silva Barud, H., Barbugli, P. A., Franzyk, Henrik, Hansen, Paul Robert & Pavan, F. R., 2024, In: Carbohydrate Polymers. 323, 17 p., 121449.

      Research output: Contribution to journalJournal articlepeer-review

    4. Published

      Effect of lipid-polymer hybrid nanoparticles on the biophysical function and lateral structure of pulmonary surfactant: Mechanistic in vitro studies

      Xu, Y., Cañadas, O., Alonso, A., Franzyk, Henrik, Thakur, A., Pérez-gil, J. & Foged, Camilla, 2024, In: Journal of Colloid and Interface Science. 654, Part B, p. 1111-1123

      Research output: Contribution to journalJournal articlepeer-review

    5. Published

      Polymyxins with Potent Antibacterial Activity against Colistin-Resistant Pathogens: Fine-Tuning Hydrophobicity with Unnatural Amino Acids

      Jørgensen, Johan Storm, Harifi Mood, Elnaz, Knap, A. S. H., Nielsen, S. E., Nielsen, Peter E., Żabicka, D., Matias, C., Domraceva, I., Björkling, Fredrik & Franzyk, Henrik, 2024, In: Journal of Medicinal Chemistry. 67, 2, p. 1370–1383

      Research output: Contribution to journalJournal articlepeer-review

    6. Published

      Studies of antibacterial activity (in vitro and in vivo) and mode of action for des-acyl tridecaptins (DATs)

      Couturier, C., Ronzon, Q., Lattanzi, G., Lingard, I., Coyne, S., Cazals, V., Dubarry, N., Yvon, S., Leroi-Geissler, C., Gracia, O. R., Teague, J., Sordello, S., Corbett, D., Bauch, C., Monlong, C., Payne, L., Taillier, T., Fuchs, H., Broenstrup, M., Harrison, P. H. & 10 others, Moynié, L., Lakshminarayanan, A., Gianga, T. M., Hussain, R., Naismith, J. H., Mourez, M., Bacqué, E., Björkling, Fredrik, Sabuco, J. F. & Franzyk, Henrik, 2024, In: European Journal of Medicinal Chemistry. 265, 20 p., 116097.

      Research output: Contribution to journalJournal articlepeer-review

    7. 2023
    8. Published

      N-acetylcysteine-chitosan nanoparticles with the Ctx(Ile21)-Ha peptide grafted onto the surface can rescue the susceptibility of pre-extensively resistant Mycobacterium tuberculosis

      Roque-Borda, C. A., Primo, L. M. D. G., Vicente, E. F., Barbugli, P. A., Franzyk, Henrik, Hansen, Paul Robert & Pavan, F. R., 2 Oct 2023. 1 p.

      Research output: Contribution to conferencePosterResearchpeer-review

    9. Published

      Rifampicin-loaded N-acetylcysteine-chitosan nanoparticles surface-grafted with a peptide exhibit potent activity against multidrug-resistant Mycobacterium tuberculosis

      Roque-Borda, C. A., Primo, L. M. D. G., Vicente, E. F., Barbugli, P. A., Franzyk, Henrik, Hansen, Paul Robert & Pavan, F. R., 11 Jun 2023. 1 p.

      Research output: Contribution to conferencePosterResearchpeer-review

    10. Published

      Elucidating the nanostructure of small interfering RNA-loaded lipidoid-polymer hybrid nanoparticles

      Aljabbari, Anas Samir Mohammad, Lokras, Abhijeet, Kirkensgaard, Jacob Judas Kain, Rades, Thomas, Franzyk, Henrik, Thakur, A., Zhang, Y. & Foged, Camilla, 2023, In: Journal of Colloid and Interface Science. 633, p. 907-922

      Research output: Contribution to journalJournal articlepeer-review

    11. Published

      Insights into the mechanisms of interaction between inhalable lipid-polymer hybrid nanoparticles and pulmonary surfactant

      Xu, Y., Parra-Ortiz, E., Wan, F., Cañadas, O., Garcia-Alvarez, B., Thakur, A., Franzyk, Henrik, Pérez-Gil, J., Malmsten, Martin & Foged, Camilla, 2023, In: Journal of Colloid and Interface Science. 633, p. 511-525

      Research output: Contribution to journalJournal articlepeer-review

    12. Published

      Method of manufacturing CAF®09 liposomes affects immune responses induced by adjuvanted subunit proteins

      Thakur, A., Wadhwa, A., Lokras, Abhijeet, Amanda Oest Müllertz, O., Christensen, D., Franzyk, Henrik & Foged, Camilla, 2023, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 189, p. 84-97

      Research output: Contribution to journalJournal articlepeer-review

    13. Published

      Optimization of the Hemolysis Assay for the Assessment of Cytotoxicity

      Sæbø, I. P., Bjørås, M., Franzyk, Henrik, Helgesen, E. & Booth, J. A., 2023, In: International Journal of Molecular Sciences. 24, 3, 20 p., 2914.

      Research output: Contribution to journalJournal articlepeer-review

    14. Published

      Physiological response in E. coli to YdgR overexpression depends on whether the protein has an intact function

      Sajid, Salvia, Salas, L. H., Rafiq, M., Lund, T., Jørgensen, M. G., Honoré, B., Christensen, L. P., Hansen, Paul Robert, Franzyk, Henrik, Mirza, Osman Asghar & Prabhala, B. K., 2023, In: Biochemical and Biophysical Research Communications. 661, p. 42-49

      Research output: Contribution to journalJournal articlepeer-review

    15. Published

      Pulmonary delivery of siRNA-loaded lipid-polymer hybrid nanoparticles: Effect of nanoparticle size

      Wadhwa, A., Bobak, T. R., Bohrmann, L., Geczy, R., Sekar, S., Sathyanarayanan, G., Kutter, Jörg P., Franzyk, Henrik, Foged, Camilla, Saatchi, K. & Häfeli, U. O., 2023, In: OpenNano. 13, 12 p., 100180.

      Research output: Contribution to journalJournal articlepeer-review

    16. Published

      Selected strategies to fight pathogenic bacteria

      Plotniece, A., Sobolev, A., Supuran, C. T., Carta, F., Björkling, Fredrik, Franzyk, Henrik, Yli-Kauhaluoma, J., Augustyns, K., Cos, P., De Vooght, L., Govaerts, M., Aizawa, J., Tammela, P. & Žalubovskis, R., 2023, In: Journal of Enzyme Inhibition and Medicinal Chemistry. 38, 1, 27 p., 2155816.

      Research output: Contribution to journalReviewpeer-review

    17. Published

      Stereoisomer-Dependent Membrane Association and Capacity for Insulin Delivery Facilitated by Penetratin

      Birch, D., Sayers, E. J., Christensen, M. V., Jones, A. T., Franzyk, Henrik & Nielsen, Hanne Mørck, 2023, In: Pharmaceutics. 15, 6, 15 p., 1672.

      Research output: Contribution to journalJournal articlepeer-review

    18. Published

      Structure-activity study of oncocin: On-resin guanidinylation and incorporation of homoarginine, 4-hydroxyproline or 4,4-difluoroproline residues

      Shaikh, Ashif Yasin, Björkling, Fredrik, Zabicka, D., Tomczak, M., Urbas, M., Domraceva, I., Kreicberga, A. & Franzyk, Henrik, 2023, In: Bioorganic Chemistry. 141, 11 p., 106876.

      Research output: Contribution to journalJournal articlepeer-review

    19. Published

      Substrate space analysis of the bacterial proton-coupled oligopeptide transporter YdgR by cheminformatics

      Sajid, Salvia, Nielsen, M. M. K., Khalil, R., Hansen, Paul Robert, Franzyk, Henrik, Jørgensen, M. G., Christensen, L. P., Mirza, Osman Asghar & Prabhala, B. K., 2023, In: FEMS Microbiology Letters. 370, 9 p., fnad052.

      Research output: Contribution to journalJournal articlepeer-review

    20. Accepted/In press

      The Y-ome Conundrum: Insights into Uncharacterized Genes and Approaches for Functional Annotation

      Sajid, Salvia, Mashkoor, M., Jørgensen, M. G., Christensen, L. P., Hansen, Paul Robert, Franzyk, Henrik, Mirza, Osman Asghar & Prabhala, B. K., 2023, (Accepted/In press) In: Molecular and Cellular Biochemistry. 12 p.

      Research output: Contribution to journalReviewpeer-review

    21. Published

      The effect of Cys15 and Cys21 replacement with Ala, Ser and Lys on the anti Mycobacterium tuberculosis activity of antimicrobial peptide B1CTcu5

      Roque-Borda, C. A., Costa de Pontes, J. T., Domingos da Silva, L. H., Caroline dos Santos, I. C. D. S., Aparecida Resende, F., Franzyk, Henrik, Hansen, Paul Robert & Pavan, F. R., 2023.

      Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

    22. 2022
    23. Published

      C-locked analogs of the antimicrobial peptide BP214

      Andersen, I. K. L., Thomsen, T. T., Rashid, J., Bobak, T. R., Oddo, A., Franzyk, Henrik, Løbner-Olesen, Anders & Hansen, Paul Robert, 2022, In: Antibiotics. 11, 8, 10 p., 1080.

      Research output: Contribution to journalJournal articlepeer-review

    24. Published

      Efficacy of natural antimicrobial peptides versus peptidomimetic analogues: a systematic review

      Hellewell, L., Gilani, N. M., Stanton, C. J., Pelligand, L., Franzyk, Henrik, Guardabassi, Luca & Good, L., 2022, In: Future Medicinal Chemistry. 14, 24, p. 1899–1921

      Research output: Contribution to journalReviewpeer-review

    25. Published

      Highly cationic cell-penetrating peptides affect the barrier integrity and facilitates mannitol permeation in a human stem cell-based blood-brain barrier model

      Frøslev, Patrick, Franzyk, Henrik, Ozgür, Burak, Larsen, Birger Brodin & Kristensen, Mie, 2022, In: European Journal of Pharmaceutical Sciences. 168, 10 p., 106054.

      Research output: Contribution to journalJournal articlepeer-review

    26. Published

      Inhalable Composite Microparticles Containing siRNA-Loaded Lipid-Polymer Hybrid Nanoparticles: Saccharides and Leucine Preserve Aerosol Performance and Long-Term Physical Stability

      Xu, You, Turan, E. T., Shi, Z., Franzyk, Henrik, Thakur, A. & Foged, Camilla, 2022, In: Frontiers in Drug Delivery. 2, 15 p., 945459.

      Research output: Contribution to journalJournal articlepeer-review

    27. Published

      Leucine improves the aerosol performance of dry powder inhaler formulations of siRNA-loaded nanoparticles

      Xu, Y., Harinck, L., Lokras, Abhijeet, Gerde, P., Selg, E., Sjöberg, C., Franzyk, Henrik, Thakur, A. & Foged, Camilla, 2022, In: International Journal of Pharmaceutics. 621, 14 p., 121758.

      Research output: Contribution to journalJournal articlepeer-review

    28. Published

      Macrolide Resistance and In Vitro Potentiation by Peptidomimetics in Porcine Clinical Escherichia coli

      Ma, Y., Pirolo, Mattia, Subramani, P., Gehring, R., Damborg, Peter Panduro, Franzyk, Henrik & Guardabassi, Luca, 2022, In: mSphere. 7, 5, 10 p., e0040222.

      Research output: Contribution to journalJournal articlepeer-review

    29. Published

      Simultaneous quantification of multiple RNA cargoes co-loaded into nanoparticle-based delivery systems

      Lokras, Abhijeet, Chakravarty, A., Rades, Thomas, Christensen, D., Franzyk, Henrik, Thakur, A. & Foged, Camilla, 2022, In: International Journal of Pharmaceutics. 626, 13 p., 122171.

      Research output: Contribution to journalJournal articlepeer-review

    30. Published

      Structural Determinants in the Staphylococcus aureus-Derived Phenol-Soluble Modulin α2 Peptide Required for Neutrophil Formyl Peptide Receptor Activation.

      Viklund, M., Fredriksson, J., Holdfeldt, A., Lind, S., Franzyk, Henrik, Dahlgren, C., Sundqvist, M. & Forsman, H., 2022, In: Journal of Immunology. 208, 7, p. 1632-1641

      Research output: Contribution to journalJournal articlepeer-review

    31. 2021
    32. Published

      Antibiotic Potentiation in Multidrug-Resistant Gram-Negative Pathogenic Bacteria by a Synthetic Peptidomimetic

      Harifi Mood, Elnaz, Goltermann, Lise, Brolin, C., Cavaco, L. M., Japoni Nejad, Alireza, Yavari, Niloofar, Frederiksen, N., Franzyk, Henrik & Nielsen, Peter E., 2021, In: ACS Infectious Diseases. 7, 8, p. 2152–2163

      Research output: Contribution to journalJournal articlepeer-review

    33. Published

      Evaluation of 1H-Triazole-1-[N,N'-Bis(tert-butoxycarbonyl)]carboxamidine in Solution-Phase and On-Resin Guanidinylation

      Wester, A., Björkling, Fredrik & Franzyk, Henrik, 2021, In: The Journal of Organic Chemistry. 86, 21, p. 14371–14380

      Research output: Contribution to journalJournal articlepeer-review

    34. Published

      Inoculum effect of antimicrobial peptides

      Loffredo, M. R., Savini, F., Bobone, S., Casciaro, B., Franzyk, Henrik, Mangoni, M. L. & Stella, L., 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 21, 10 p., e2014364118.

      Research output: Contribution to journalJournal articlepeer-review

    35. Published

      Neuroprotection Against NMDA-Induced Retinal Damage by Philanthotoxin-343 Involves Reduced Nitrosative Stress

      Mohamad, M. H. N., Abu, I. F., Fazel, M. F., Agarwal, R., Iezhitsa, I., Juliana, N., Mellor, I. R. & Franzyk, Henrik, 2021, In: Frontiers in Pharmacology. 12, 11 p., 798794.

      Research output: Contribution to journalJournal articlepeer-review

    36. Published

      Optimized Synthesis of Fmoc/Boc-Protected PNA Monomers and their Assembly into PNA Oligomers.

      Shaikh, Ashif Yasin, Björkling, Fredrik, Nielsen, Peter E. & Franzyk, Henrik, 2021, In: European Journal of Organic Chemistry. 2021, 19, p. 2792-2801 10 p.

      Research output: Contribution to journalJournal articlepeer-review

    37. Published

      Peptide/β-Peptoid Hybrids with Activity against Vancomycin-Resistant Enterococci: Influence of Hydrophobicity and Structural Features on Antibacterial and Hemolytic Properties

      Vestergaard, M., Skive, Bolette, Domraceva, I., Ingmer, Hanne & Franzyk, Henrik, 2021, In: International Journal of Molecular Sciences. 22, 11, 5617.

      Research output: Contribution to journalJournal articlepeer-review

    38. Published

      Peptide/β-Peptoid Hybrids with Ultrashort PEG-Like Moieties: Effects on Hydrophobicity, Antibacterial Activity and Hemolytic Properties

      Frederiksen, N., Louka, S., Mudaliar, C., Domraceva, I., Kreicberga, A., Pugovics, O., Żabicka, D., Tomczak, M., Wygoda, W., Björkling, Fredrik & Franzyk, Henrik, 2021, In: International Journal of Molecular Sciences. 22, 13, 17 p., 7041.

      Research output: Contribution to journalJournal articlepeer-review

    39. Published

      Perfluoro-tert-butanol for selective on-resin detritylation: a mild alternative to traditionally used methods

      Wester, A., Hansen, A. M., Hansen, Paul Robert & Franzyk, Henrik, 2021, In: Amino Acids. 53, p. 1455–1466

      Research output: Contribution to journalJournal articlepeer-review

    40. Published

      Reversal of ABCG2/BCRP-mediated multidrug resistance by 5,3’,5’-trihydroxy-3,6,7,4’-tetramethoxyflavone isolated from the Australian desert plant Eremophila galeata Chinnock

      Petersen, M. J., Lund, X. L., Semple, S. J., Buirchell, B., Franzyk, Henrik, Gajhede, Michael, Kongstad, Kenneth Thermann, Stenvang, Jan & Stærk, Dan, 2021, In: Biomolecules. 11, 10, 19 p., 1534.

      Research output: Contribution to journalJournal articlepeer-review

    41. Published

      Targeting Toxins toward Tumors

      Franzyk, Henrik & Christensen, Søren Brøgger, 2021, In: Molecules. 26, 5, 23 p., 1292.

      Research output: Contribution to journalJournal articlepeer-review

    42. Published

      The Effects of Structural Alterations in the Polyamine and Amino Acid Moieties of Philanthotoxins on Nicotinic Acetylcholine Receptor Inhibition in the Locust, Schistocerca gregaria

      Luck, V. L., Richards, D. P., Shaikh, Ashif Yasin, Franzyk, Henrik & Mellor, I. R., 2021, In: Molecules (Print Archive Edition). 26, 22, 11 p., 7007.

      Research output: Contribution to journalJournal articlepeer-review

    43. 2020
    44. Published

      Alternating Cationic-Hydrophobic Peptide/Peptoid Hybrids: Influence of Hydrophobicity on Antibacterial Activity and Cell Selectivity

      Frederiksen, N., Hansen, Paul Robert, Zabicka, D., Tomczak, M., Urbas, M., Domraceva, I., Björkling, Fredrik & Franzyk, Henrik, 2020, In: ChemMedChem. 15, 24, p. 2544-2561

      Research output: Contribution to journalJournal articlepeer-review

    45. Published

      Antidiabetic xanthones with α-glucosidase inhibitory activities from an endophytic Penicillium canescens

      Malik, A., Ardalani, H., Anam, S., McNair, Laura M., Kromphardt, K. J. K., Frandsen, R. J. N., Franzyk, Henrik, Stærk, Dan & Kongstad, Kenneth Thermann, 2020, In: Fitoterapia. 142, 8 p., 104522.

      Research output: Contribution to journalJournal articlepeer-review

    46. Published

      Barbadin selectively modulates FPR2-mediated neutrophil functions independent of receptor endocytosis

      Sundqvist, M., Holdfeldt, A., Wright, S. C., Møller, T. C., Siaw, E., Jennbacken, K., Franzyk, Henrik, Bouvier, M., Dahlgren, C. & Forsman, H., 2020, In: B B A - Molecular Cell Research. 1867, 12, 13 p., 118849.

      Research output: Contribution to journalJournal articlepeer-review

    47. Published

      Facile Preparation of PNA-Peptide Conjugates with a Polar Maleimide-Thioether Linkage

      Hansen, A. M., Shaikh, Ashif Yasin & Franzyk, Henrik, 2020, Peptide Nucleic Acids: Methods and Protocols. P. E. N. (ed.). Humana Press, p. 97-118 22 p. (Methods in molecular biology (Clifton, N.J.), Vol. 2105).

      Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

    48. Published

      Fluorescent analogues of Human α-Calcitonin Gene-Related Peptide with vasodilator potency

      Zhu, J., Pedersen, M. D., Ahmed, L. S., Abdolalizadeh, B., Grell, A., Berg, Jais Oliver, Thulstrup, Peter Waaben, Franzyk, Henrik, Edvinsson, L., Sams, A., Sheykhzade, Majid & Hansen, Paul Robert, 2020, In: International Journal of Molecular Sciences (Online). 21, 4, p. 1-15 15 p., 1343.

      Research output: Contribution to journalJournal articlepeer-review

    49. Published

      Fmoc-Based Assembly of PNA Oligomers: Manual and Microwave-Assisted Automated Synthesis

      Shaikh, Ashif Yasin, Hansen, A. M. & Franzyk, Henrik, 2020, Peptide Nucleic Acids: Methods and Protocols. P. E. N. (ed.). Humana Press, p. 1-16 16 p. (Methods in molecular biology (Clifton, N.J.), Vol. 2105).

      Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

    50. Published

      In vivo Anti-inflammatory Activity of Lipidated Peptidomimetics Pam-(Lys-βNspe)6-NH2 and Lau-(Lys-βNspe)6-NH2 Against PMA-Induced Acute Inflammation

      Wu, B. C., Skovbakke, S. L., Masoudi, H., Hancock, R. E. W. & Franzyk, Henrik, 2020, In: Frontiers in Immunology. 11, 11 p., 2102.

      Research output: Contribution to journalJournal articlepeer-review

    51. Published

      Missing Selectivity of Targeted 4β-Phorbol Prodrugs Expected to be Potential Chemotherapeutics

      Tarvainen, I., Zimmermann, T., Heinonen, P., Jäntti, M. H., Yli-Kauhaluoma, J., Talman, V., Franzyk, Henrik, Tuominen, R. K. & Christensen, Søren Brøgger, 2020, In: A C S Medicinal Chemistry Letters. 11, 5, p. 671-677 6 p.

      Research output: Contribution to journalJournal articlepeer-review

    52. Published

      Novel Cyclic Lipopeptide Antibiotics: Effects of Acyl Chain Length and Position

      Jensen, S. K., Thomsen, T. T., Oddo, A., Franzyk, Henrik, Løbner-Olesen, Anders & Hansen, Paul Robert, 2020, In: International Journal of Molecular Sciences . 21, 16, 18 p., 5829.

      Research output: Contribution to journalJournal articlepeer-review

    53. Published

      Optimizing the Intracellular Delivery of Therapeutic Anti-inflammatory TNF-α siRNA to Activated Macrophages Using Lipidoid-Polymer Hybrid Nanoparticles

      Lokras, Abhijeet, Thakur, A., Wadhwa, A., Thanki, K., Franzyk, Henrik & Foged, Camilla, 2020, In: Frontiers in Bioengineering and Biotechnology. 8, 14 p., 601155.

      Research output: Contribution to journalJournal articlepeer-review

    54. Published

      Philanthotoxin-343 attenuates retinal and optic nerve injury, and protects visual function in rats with N-methyl-D-aspartate-induced excitotoxicity

      Fazel, M. F., Abu, I. F., Mohamad, M. H. N., Agarwal, R., Iezhitsa, I., Bakar, N. S., Juliana, N., Mellor, I. R. & Franzyk, Henrik, 2020, In: PLoS ONE. 15, 7, 14 p., e0236450.

      Research output: Contribution to journalJournal articlepeer-review

    55. 2019
    56. Published

      Peptide/Peptoid Hybrid Oligomers: The Influence of Hydrophobicity and Relative Side-Chain Length on Antibacterial Activity and Cell Selectivity

      Frederiksen, N., Hansen, Paul Robert, Björkling, Fredrik & Franzyk, Henrik, 4 Dec 2019, In: Molecules (Print Archive Edition). 24, 18 p., 4429.

      Research output: Contribution to journalJournal articlepeer-review

    57. Published

      Philanthotoxin Analogues That Selectively Inhibit Ganglionic Nicotinic Acetylcholine Receptors with Exceptional Potency

      Kachel, H. S., Franzyk, Henrik & Mellor, I. R., 11 Jul 2019, In: Journal of Medicinal Chemistry. 62, 13, p. 6214-6222

      Research output: Contribution to journalJournal articlepeer-review

    58. Published

      Repurposing Azithromycin and Rifampicin Against Gram-Negative Pathogens by Combination With Peptidomimetics

      Baker, K. R., Jana, B., Hansen, A. M., Nielsen, Hanne Mørck, Franzyk, Henrik & Guardabassi, Luca, 2 Jul 2019, In: Frontiers in Cellular and Infection Microbiology. 9

      Research output: Contribution to journalJournal articlepeer-review

    59. Published

      Macrophage phosphoproteome analysis reveals MINCLE-dependent and -independent mycobacterial cord factor signaling

      Hansen, M., Peltier, J., Killy, B., Amin, B., Bodendorfer, B., Härtlova, A., Uebel, S., Bosmann, M., Hofmann, J., Büttner, C., Ekici, A. B., Kuttke, M., Franzyk, Henrik, Foged, Camilla, Beer-Hammer, S., Schabbauer, G., Trost, M. & Lang, R., Apr 2019, In: Molecular and Cellular Proteomics. 18, 4, p. 669-685

      Research output: Contribution to journalJournal articlepeer-review

    60. Published

      Structure-Function Characteristics and Signaling Properties of Lipidated Peptidomimetic FPR2 Agonists: Peptoid Stereochemistry and Residues in the Vicinity of the Headgroup Affect Function

      Holdfeldt, A., Skovbakke, S. L., Gabl, M., Nielsen, C., Dahlgren, C., Franzyk, Henrik & Forsman, H., 28 Mar 2019, In: ACS Omega. 4, 3, p. 5968-5982 15 p.

      Research output: Contribution to journalJournal articlepeer-review

    61. Published

      19F-substituted amino acids as an alternative to fluorophore labels: monitoring of degradation and cellular uptake of analogues of penetratin by 19F NMR

      Christensen, M. V., Kongstad, Kenneth Thermann, Sondergaard, T. E., Stærk, Dan, Nielsen, Hanne Mørck, Franzyk, Henrik & Wimmer, R., 2019, In: Journal of Biomolecular N M R. 73, p. 167-182

      Research output: Contribution to journalJournal articlepeer-review

    62. Published

      Antimicrobial Activity of α-Peptide/β-Peptoid Lysine-Based Peptidomimetics Against Colistin-Resistant Pseudomonas aeruginosa Isolated From Cystic Fibrosis Patients

      Molchanova, N., Wang, H., Hansen, Paul Robert, Høiby, Niels, Nielsen, Hanne Mørck & Franzyk, Henrik, 2019, In: Frontiers in Microbiology. 10, 9 p., 275.

      Research output: Contribution to journalJournal articlepeer-review

    63. Published

      Application of a Quality-By-Design Approach to Optimise Lipid-Polymer Hybrid Nanoparticles Loaded with a Splice-Correction Antisense Oligonucleotide: Maximising Loading and Intracellular Delivery

      Thanki, K., Papai, S., Lokras, Abhijeet, Rose, F., Falkenberg, E., Franzyk, Henrik & Foged, Camilla, 2019, In: Pharmaceutical Research. 36, 3, 37.

      Research output: Contribution to journalJournal articlepeer-review

    64. Published

      Comparison of two different PEGylation strategies for the liposomal adjuvant CAF09: Towards induction of CTL responses upon subcutaneous vaccine administration

      Tandrup Schmidt, S., Line Olsen, C., Franzyk, Henrik, Wørzner, K., Smith Korsholm, K., Rades, Thomas, Andersen, P., Foged, Camilla & Christensen, D., 2019, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 140, p. 29-39 11 p.

      Research output: Contribution to journalJournal articlepeer-review

    65. Published

      Identification of Factors of Importance for Spray Drying of Small Interfering RNA-Loaded Lipidoid-Polymer Hybrid Nanoparticles for Inhalation

      Dormenval, C., Lokras, Abhijeet, Cano-Garcia, G., Wadhwa, A., Thanki, K., Rose, F., Thakur, A., Franzyk, Henrik & Foged, Camilla, 2019, In: Pharmaceutical Research. 36, 10, 142.

      Research output: Contribution to journalJournal articlepeer-review

    66. Published

      Lipidoid-Polymer Hybrid Nanoparticles Loaded with TNF siRNA Suppress Inflammation after Intra-articular Administration in a Murine Experimental Arthritis Model

      Jansen, M. A. A., Klausen, L. H., Thanki, K., Lyngsø, J., Skov Pedersen, J., Franzyk, Henrik, Nielsen, Hanne Mørck, van Eden, W., Dong, M., Broere, F., Foged, Camilla & Zeng, X., 2019, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 142, p. 38-48

      Research output: Contribution to journalJournal articlepeer-review

    67. Published

      Mechanistic profiling of the release kinetics of siRNA from lipidoid-polymer hybrid nanoparticles in vitro and in vivo after pulmonary administration

      Thanki, K., van Eetvelde, D., Geyer, A., Fraire, J., Hendrix, R., Van Eygen, H., Putteman, E., Sami, H., de Souza Carvalho-Wodarz, C., Franzyk, Henrik, Nielsen, Hanne Mørck, Braeckmans, K., Lehr, C., Ogris, M. & Foged, Camilla, 2019, In: Journal of controlled release : official journal of the Controlled Release Society. 310, p. 82-93

      Research output: Contribution to journalJournal articlepeer-review

    68. Published

      Microwave-assisted solid-phase synthesis of antisense acpP peptide nucleic acid-peptide conjugates active against colistin- and tigecycline-resistant E. coli and K. pneumoniae

      Hansen, A. M., Bonke, G., Hogendorf, W. F. J., Björkling, Fredrik, Nielsen, J., Kongstad, Kenneth Thermann, Zabicka, D., Tomczak, M., Urbas, M., Nielsen, Peter E. & Franzyk, Henrik, 2019, In: European Journal of Medicinal Chemistry. 168, p. 134-145 12 p.

      Research output: Contribution to journalJournal articlepeer-review

    69. Published

      Repurposing azithromycin and rifampicin against Gram-negative pathogens by combination with peptide potentiators

      Baker, K. R., Jana, B., Hansen, A. M., Vissing, K. J., Nielsen, Hanne Mørck, Franzyk, Henrik & Guardabassi, Luca, 2019, In: International Journal of Antimicrobial Agents. 53, p. 868-872 5 p.

      Research output: Contribution to journalJournal articlepeer-review

    70. Published

      Studies on acid stability and solid-phase block synthesis of peptide-peptoid hybrids: ligands for formyl peptide receptors

      Hansen, A. M., Skovbakke, S. L., Christensen, S. B., Perez-Gassol, I. & Franzyk, Henrik, 2019, In: Amino Acids. 51, p. 205-218

      Research output: Contribution to journalJournal articlepeer-review

    71. 2018
    72. Published

      Phorbol Rearrangements

      Zimmermann, T., Franzyk, Henrik & Christensen, Søren Brøgger, 28 Sep 2018, In: Journal of Natural Products. 81, 9, p. 2134-2137 4 p.

      Research output: Contribution to journalJournal articlepeer-review

    73. Published

      Immune responses induced by nano-self-assembled lipid adjuvants based on a monomycoloyl glycerol analogue after vaccination with the Chlamydia trachomatis major outer membrane protein

      Rodrigues, L., Raftopoulos, K. N., Tandrup Schmidt, S., Schneider, F., Dietz, H., Rades, Thomas, Franzyk, Henrik, Pedersen, Anders Elm, Papadakis, C. M., Christensen, D., Winter, G., Foged, Camilla & Hubert, M., 10 Sep 2018, In: Journal of controlled release : official journal of the Controlled Release Society. 285, p. 12-22 11 p.

      Research output: Contribution to journalJournal articlepeer-review

    74. Published

      Non-natural Amino Acid and Peptoid Building Blocks for Optimization of the Cell-Penetrating (R-X-R)n Motif

      Wester, A., Björkling, Fredrik, Nieslen, P. & Franzyk, Henrik, Sep 2018, In: Journal of Peptide Science. 24, p. S94-S94

      Research output: Contribution to journalConference abstract in journalpeer-review

    75. Published

      Structure-Activity Study of alpha-Peptoid/alpha-Peptide Peptidomimetics: Influence of Hydrophobicity on Antimicrobial Activity and Cytotoxicity

      Frederiksen, N., Bjorkling, F., Nielsen, P. & Franzyk, Henrik, Sep 2018, In: Journal of Peptide Science. 24, s2, p. S120-S120

      Research output: Contribution to journalConference abstract in journalpeer-review

    76. Published

      Biopolymer nanogels improve antibacterial activity and safety profile of a novel lysine-based α-peptide/β-peptoid peptidomimetic

      Kłodzińska, S. N., Molchanova, N., Franzyk, Henrik, Hansen, Paul Robert, Damborg, Peter Panduro & Nielsen, Hanne Mørck, Jul 2018, In: European Journal of Pharmaceutics and Biopharmaceutics. 128, p. 1-9 9 p.

      Research output: Contribution to journalJournal articlepeer-review

    77. Published

      Preparation of Enzyme-Activated Thapsigargin Prodrugs by Solid-Phase Synthesis

      Zimmermann, T., Christensen, Søren Brøgger & Franzyk, Henrik, 15 Jun 2018, In: Molecules. 23, 6, 13 p., 1463.

      Research output: Contribution to journalJournal articlepeer-review

    78. Published

      Immunogenicity Testing of Lipidoids In Vitro and In Silico: Modulating Lipidoid-Mediated TLR4 Activation by Nanoparticle Design

      de Groot, A. M., Thanki, K., Gangloff, M., Falkenberg, E., Zeng, X., van Bijnen, D. C. J., van Eden, W., Franzyk, Henrik, Nielsen, Hanne Mørck, Broere, F., Gay, N. J., Foged, Camilla & Sijts, A. J. A. M., 1 Jun 2018, In: Molecular Therapy - Nucleic Acids. 11, p. 159-169 11 p.

      Research output: Contribution to journalJournal articlepeer-review

    79. Published

      Stereochemistry as a determining factor for the effect of a cell-penetrating peptide on cellular viability and epithelial integrity

      Birch, D., Christensen, M. V., Stærk, Dan, Franzyk, Henrik & Nielsen, Hanne Mørck, 24 May 2018, In: Biochemical Journal. 475, 10, p. 1773-1788 16 p.

      Research output: Contribution to journalJournal articlepeer-review

    80. Submitted
    81. Published

      Comparative study of the drug delivery mechanism of L-penetratin and D-penetratin

      Birch, D., Christensen, M. V., Stærk, Dan, Franzyk, Henrik & Nielsen, Hanne Mørck, 2018.

      Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

    82. Published

      Fastfase-syntese af Peptider - en visuel guide

      Franzyk, Henrik, 2018, 18 p.

      Research output: Book/ReportCompendium/lecture notes

    83. Published

      Fluorinated antimicrobial lysine-based peptidomimetics with activity against methicillin-resistant Staphylococcus pseudintermedius

      Molchanova, N., Hansen, Paul Robert, Damborg, Peter Panduro & Franzyk, Henrik, 2018, In: Journal of Peptide Science. 24, 7, 8 p., e3098.

      Research output: Contribution to journalJournal articlepeer-review

    84. Published

      Fluorophore labeling of a cell-penetrating peptide significantly alters the mode and degree of biomembrane interaction

      Hedegaard, S. F., Derbas, M. S., Lind, T. K., Kasimova, M. R., Christensen, M. V., Michaelsen, M. H., Campbell, R. A., Jørgensen, Lene, Franzyk, Henrik, Cárdenas, M. & Nielsen, Hanne Mørck, 2018, In: Scientific Reports. 8, 1, 14 p., 6327.

      Research output: Contribution to journalJournal articlepeer-review

    85. Published

      Guide til Rapportskrivning i Kurset Biopharmaceuticals: Bioorganisk Kemi 2018

      Franzyk, Henrik, 2018, 17 p.

      Research output: Book/ReportCompendium/lecture notes

    86. Published

      High-resolution PTP1B inhibition profiling combined with HPLC-HRMS-SPE-NMR for identification of PTP1B inhibitors from Miconia albicans

      Lima, R. D. C. L., Kongstad, Kenneth Thermann, Kato, L., José das Silva, M., Franzyk, Henrik & Stærk, Dan, 2018, In: Molecules. 23, 7, 13 p., 1755.

      Research output: Contribution to journalJournal articlepeer-review

    87. Published

      Identification and characterization of a new antifungal peptide in fermented milk product containing bioprotective Lactobacillus cultures

      McNair, Laura M., Siedler, S., Vinther, J. M., Hansen, A. M., Neves, A. R., Jäger, A. K., Franzyk, Henrik & Stærk, Dan, 2018, In: F E M S Yeast Research. 18, 9 p., foy094.

      Research output: Contribution to journalJournal articlepeer-review

    88. Published

      Lactam hybrid analogues of solonamide B and autoinducing peptides as potent S. aureus AgrC antagonists

      Hansen, A. M., Peng, P., Baldry, M., Perez-Gassol, I., Christensen, S. B., Vinther, J. M., Ingmer, Hanne & Franzyk, Henrik, 2018, In: European Journal of Medicinal Chemistry. 152, p. 370-376 7 p.

      Research output: Contribution to journalJournal articlepeer-review

    89. Published

      Lipid-polymer hybrid nanoparticles (LPNs) for efficient pulmonary delivery of nucleic acids: Lessons learnt from quality-by-design based optimization, immunogenicity studies, in vitro release experiments, in vivo biodistribution and efficacy studies

      Thanki, K., Thakur, A., de Groot, A. M., Geyer, A., Fraire, J., Falkenberg, E., Van Eygen, H., Putteman, E., Van Bijnen, D. C. J., Zeng, X., Sami, H., Gehrig, S., Justesen, S., Franzyk, H., Broere, F., van Eden, W., Sijts, A. J. A. M., Ogris, M., Nielsen, H. M., Braeckmans, K. & 1 others, Foged, Camilla, 2018.

      Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

    90. Published

      Mini-manual: Søgninger i Reaxys

      Franzyk, Henrik, 2018, 4 p.

      Research output: Book/ReportCompendium/lecture notes

    91. Published

      The Role of Formyl Peptide Receptors for Immunomodulatory Activities of Antimicrobial Peptides and Peptidomimetics

      Skovbakke, S. L., Holdfeldt , A., Forsman, H., Bylund, J. & Franzyk, Henrik, 2018, In: Current Pharmaceutical Design. 24, 10, p. 1100-1120 21 p.

      Research output: Contribution to journalReviewpeer-review

    92. Published
    93. 2017
    94. Published

      Engineering of small interfering RNA-loaded lipidoid-poly(DL-lactic-co-glycolic acid) hybrid nanoparticles for highly efficient and safe gene silencing: A quality by design-based approach

      Thanki, K., Zeng, X., Justesen, S., Tejlmann, S., Falkenberg, E., Van Driessche, E., Nielsen, Hanne Mørck, Franzyk, Henrik & Foged, Camilla, Nov 2017, In: European Journal of Pharmaceutics and Biopharmaceutics. 120, p. 22-33 12 p.

      Research output: Contribution to journalJournal articlepeer-review

    95. Published

      Nanoparticle compositions comprising PLGA derivatives and a lipid for delivery of drugs, in particular nucleic acids, especially siRNA

      Foged, Camilla, Franzyk, Henrik, Zeng, X., Nielsen, Hanne Mørck & Thanki, K., 21 Sep 2017, IPC No. A61K31/713, A61K47/18, A61K47/34, A61K9/51, A61P25/00, A61P29/00, A61P35/00, Patent No. WO2017158093-A1, 16 Mar 2017, Priority date 17 Mar 2016, Priority No. EP 2016-160931

      Research output: Patent

    96. Published

      Advances in development of antimicrobial peptidomimetics as potential drugs

      Molchanova, N., Hansen, Paul Robert & Franzyk, Henrik, 28 Aug 2017, In: Molecules. 22, 9, 60 p., 1430.

      Research output: Contribution to journalReviewpeer-review

    97. Published

      Adjuvants based on synthetic mycobacterial cord factor analogues: Biophysical properties of neat glycolipids and nano-self-assemblies with DDA

      Kallerup, R. S., Franzyk, Henrik, Schiøth, M. L., Justesen, S., Martin-Bertelsen, Birte, Rose, F., Madsen, C. M., Christensen, D., Korsholm, K. S., Yaghmur, Anan & Foged, Camilla, 12 May 2017, In: Molecular Pharmaceutics. 14, 7, p. 2294-2306 13 p.

      Research output: Contribution to journalJournal articlepeer-review

    98. Published

      An approach to identify clinically relevan, non-toxic peptide-antimicrobial combinations that eliminate intrinsic resistance in Gram-negative pathogens

      Baker, K. R., Jana, B., Nielsen, Hanne Mørck, Franzyk, Henrik & Guardabassi, Luca, 2017. 1 p.

      Research output: Contribution to conferenceConference abstract for conferenceResearch

    99. Published

      Anti-inflammatory Properties of Antimicrobial Peptides and Peptidomimetics: LPS and LTA Neutralization

      Skovbakke, S. L. & Franzyk, Henrik, 2017, Methods Molecular Biology: Antimicrobial Peptides. Hansen, P. R. (ed.). Springer, Vol. 1548. p. 369-386 18 p. (Methods in Molecular Biology, Vol. 1548).

      Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

    100. Published

      Antisense PNA antibiotics against multiresistant Gram-negative bacteria

      Nielsen, Peter E., Björkling, Fredrik & Franzyk, Henrik, 2017, In: International Journal of Molecular Medicine. 40, Suppl. 1, p. S22 1 p., Abstract 169.

      Research output: Contribution to journalConference abstract in journal

    101. Published

      Biopolymer-based nanogels improve the safety profile and antimicrobial activity of a lysine-based peptidomimetic.

      Franzyk, Henrik, 2017.

      Research output: Contribution to conferencePosterResearchpeer-review

    102. Published

      Combining elements from two antagonists of formyl peptide receptor 2 generates more potent peptidomimetic antagonists

      Skovbakke, S. L., Holdfeldt, A., Nielsen, C., Hansen, A. M., Perez-Gassol, I., Dahlgren, C., Forsman, H. & Franzyk, Henrik, 2017, In: Journal of Medicinal Chemistry. 60, 16, p. 6991-6997

      Research output: Contribution to journalJournal articlepeer-review

    103. Published

      Efficient Pulmonary Delivery of siRNA Using Lipid-polymer Hybrid Nanoparticles (LPNs): A quality-by-design approach for highly systematic optimization of LPNs

      Thanki, K., Zeng, X., Justesen, S., Tejlmann, S., Falkenberg, E., Nielsen, Hanne Mørck, Franzyk, Henrik & Foged, Camilla, 2017.

      Research output: Contribution to conferencePosterResearch

    104. Published

      Fluorophore labeling of a cell-penetrating peptide induces differential effects on its cellular distribution and affects cell viability

      Birch, D., Christensen, M. V., Stærk, Dan, Franzyk, Henrik & Nielsen, Hanne Mørck, 2017, In: B B A - Biomembranes. 1859, 12, p. 2483-2494

      Research output: Contribution to journalJournal articlepeer-review

    105. Published
    106. Published

      On-resin N-formylation of peptides: a head-to-head comparison of reagents in solid-phase synthesis of ligands for formyl peptide receptors

      Christensen, S. B., Hansen, A. M. & Franzyk, Henrik, 2017, In: Journal of Peptide Science. 23, 5, p. 410-415 6 p.

      Research output: Contribution to journalJournal articlepeer-review

    107. Published
    108. Published

      Structure-activity relationship studies of lysine-based α-peptide/β-peptoid antimicrobial peptidomimetics

      Molchanova, N., Hansen, Paul Robert, Damborg, Peter Panduro & Franzyk, Henrik, 2017. 1 p.

      Research output: Contribution to conferencePosterResearchpeer-review

    109. Published

      Synergistic peptidomimetic-antimicrobial combinations to combat multidrug-resistant Gram-negative bacterial infections

      Baker, K. R., Jana, B., Franzyk, Henrik & Guardabassi, Luca, 2017. 1 p.

      Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

    110. Published

      Synthesis and Characterisation of an Array of Lipidoid Analogues for RNA Interference Therapy

      Falkenberg, E., de Groot, A. M., Sijts, A. J. A. M., Thanki, K., Zeng, X., Nielsen, Hanne Mørck, Franzyk, Henrik & Foged, Camilla, 2017.

      Research output: Contribution to conferencePosterResearch

    111. 2016
    112. Published

      Block of nicotinic acetylcholine receptors by philanthotoxins is strongly dependent on their subunit composition

      Kachel, H. S., Patel, R. N., Franzyk, Henrik & Mellor, I. R., 30 Nov 2016, In: Scientific Reports. 6, p. 1-13 13 p., 38116.

      Research output: Contribution to journalJournal articlepeer-review

    113. Published

      Conserved molecular superlattices in a series of homologous synthetic mycobacterial cell-wall lipids forming interdigitated bilayers

      Martin-Bertelsen, Birte, Yaghmur, Anan, Franzyk, Henrik, Justesen, S., Kirkensgaard, Jacob Judas Kain & Foged, Camilla, 7 Nov 2016, In: Langmuir. 32, 48, p. 12693–12701 9 p.

      Research output: Contribution to journalJournal articlepeer-review

    114. Published

      A high-throughput approach to identify compounds that impair envelope integrity in Escherichia coli

      Baker, K. R., Jana, B., Franzyk, Henrik & Guardabassi, Luca, Oct 2016, In: Antimicrobial Agents and Chemotherapy. 60, 10, p. 5995-6002 8 p.

      Research output: Contribution to journalJournal articlepeer-review

    115. Published

      The peptidomimetic Lau-(Lys-βNSpe)6-NH2 antagonizes formyl peptide receptor 2 expressed in mouse neutrophils

      Skovbakke, S. L., Winther, M., Gabl, M., Holdfeldt, A., Linden, S., Wang, J. M., Dahlgren, C., Franzyk, Henrik & Forsman, H., 8 Sep 2016, In: Biochemical Pharmacology. 119, p. 56-65 10 p.

      Research output: Contribution to journalJournal articlepeer-review

    116. Published

      Noter til BIOPHARMACEUTICALS: BIOORGANISK KEMI

      Franzyk, Henrik & Nielsen, Peter E., 15 Aug 2016, Dept. Drug Design and Pharmacology. 159 p.

      Research output: Book/ReportCompendium/lecture notes

    117. Published

      ØVELSESVEJLEDNING TIL: Øvelsesdelen af Biopharmaceuticals: Bioorganisk Kemi

      Franzyk, Henrik, 15 Aug 2016, Dept. Drug Design and Pharmacology. 60 p.

      Research output: Book/ReportCompendium/lecture notes

    118. Published

      Trehalose diester glycolipids are superior to the monoesters in binding to Mincle, activation of macrophages invitro and adjuvant activity invivo

      Huber, A., Kallerup, R. S., Korsholm, K. S., Franzyk, Henrik, Lepenies, B., Christensen, D., Foged, Camilla & Lang, R., Aug 2016, In: Innate Immunity. 22, 6, p. 405-418 14 p.

      Research output: Contribution to journalJournal articlepeer-review

    119. Published

      Delivery of siRNA Complexed with Palmitoylated α-Peptide/β-Peptoid Cell-Penetrating Peptidomimetics: Membrane Interaction and Structural Characterization of a Lipid-Based Nanocarrier System.

      Jing, X., Foged, Camilla, Martin-Bertelsen, Birte, Yaghmur, Anan, Knapp, K. M., Malmsten, M., Franzyk, Henrik & Nielsen, Hanne Mørck, 6 Jun 2016, In: Molecular Pharmaceutics. 13, 6, p. 1739-1749 11 p.

      Research output: Contribution to journalJournal articlepeer-review

    120. Published

      Improved in vitro evaluation of novel antimicrobials: potential synergy between human plasma and antibacterial peptidomimetics, AMPs, or antibiotics against human pathogenic bacteria

      Citterio, L., Franzyk, Henrik, Palarasah, Y., Andersen, T. E., Mateiu, R. V. & Gram, L., Feb 2016, In: Research in Microbiology. 167, 2, p. 72-82 11 p.

      Research output: Contribution to journalJournal articlepeer-review

    121. Published

      An amphipathic undecapeptide with all D-amino acids shows promising activity against colistin-resistant strains of Acinetobacter baumannii and a dual mode of action

      Oddo, A., Thomsen, T. T., Kjelstrup, S., Gorey, C., Franzyk, Henrik, Frimodt-Møller, N., Løbner-Olesen, Anders & Hansen, Paul Robert, 2016, In: Antimicrobial Agents and Chemotherapy. 60, 1, p. 592-599 8 p.

      Research output: Contribution to journalJournal articlepeer-review

    122. Published

      Antibacterial Peptide Nucleic Acid-Antimicrobial Peptide (PNA-AMP) Conjugates: Antisense Targeting of Fatty Acid Biosynthesis

      Hansen, A. M., Bonke, G., Larsen, C. J., Yavari, Niloofar, Nielsen, Peter E. & Franzyk, Henrik, 2016, In: Bioconjugate Chemistry. 27, 4, p. 863-867 5 p.

      Research output: Contribution to journalJournal articlepeer-review

    123. Published

      Breaching bacterial barricades: A high-throughput approach to identify compounds targeting envelope integrity

      Baker, K. R., Jana, B., Franzyk, Henrik & Guardabassi, Luca, 2016. 1 p.

      Research output: Contribution to conferencePosterResearch

    124. Published
    125. Published

      Iminolactones as Tools for Inversion of the Absolute Configuration of alpha-Amino Acids and as Inhibitors of Cancer Cell Proliferation

      Jensen, C. M., Chow, H., Chen, M., Zhai, L., Frydenvang, Karla Andrea, Liu, H., Franzyk, Henrik & Christensen, Søren Brøgger, 2016, In: European Journal of Medicinal Chemistry. 114, p. 118-133 16 p.

      Research output: Contribution to journalJournal articlepeer-review

    126. Published

      Nano-self-assemblies based on synthetic analogues of mycobacterial monomycoloyl glycerol and DDA: Supramolecular structure and adjuvant efficacy

      Martin-Bertelsen, Birte, Korsholm, K. S., Christensen, D., Franzyk, Henrik, Yaghmur, Anan & Foged, Camilla, 2016, In: Molecular Pharmaceutics. 13, 8, p. 2771-2781 11 p.

      Research output: Contribution to journalJournal articlepeer-review

    127. Published

      Peptidomimetics as novel formyl peptide receptor 2 (FPR2) modulators in human and mouse neutrophils

      Holdfeldt, A., Dahlgren, C., Forsman, H., Skovbakke, S. L. & Franzyk, Henrik, 2016.

      Research output: Contribution to conferencePosterResearch

    128. Published
    129. Published

      Soft hydrogels interpenetrating silicone – a polymer network for drug releasing medical devices

      Steffensen, S. L., Merete H., V., Møller, E. H., Jensen, M. G., Alm, M., Franzyk, Henrik & Nielsen, Hanne Mørck, 2016, In: Journal of Biomedical Materials Research. Part B: Applied Biomaterials. 104, 2, p. 402-410 9 p.

      Research output: Contribution to journalJournal articlepeer-review

    130. Published

      The agr inhibitors solonamide B and analogues alter immune responses to Staphylococccus aureus but do not exhibit adverse effects on immune cell functions

      Baldry, M., Kitir, B., Frøkiær, Hanne, Christensen, S. B., Taverne, N., Meijerink, M., Franzyk, Henrik, Olsen, Christian Adam, Wells, J. M. & Ingmer, Hanne, 2016, In: P L o S One. 11, 1, 17 p., e0145618.

      Research output: Contribution to journalJournal articlepeer-review

    131. Published

      The Lipidated Peptidomimetic Lau-((S)-Aoc)-(Lys-βNphe)6-NH2Is a Novel Formyl Peptide Receptor 2 Agonist That Activates Both Human and Mouse Neutrophil NADPH Oxidase

      Holdfeldt, A., Skovbakke, S. L., Winther, M., Gabl, M., Nielsen, C., Perez-Gassol, I., Larsen, C. J., Wang, J. M., Karlsson, A., Dahlgren, C., Forsman, H. & Franzyk, Henrik, 2016, In: Journal of Biological Chemistry. 12 p.

      Research output: Contribution to journalJournal articlepeer-review

    132. Published

      The lipidated peptidomimetic Lau-[(S)-Aoc]-(Lys-βNphe)6-NH2 is a novel formyl peptide receptor 2 agonist that activates both human and mouse neutrophil NADPH-oxidase

      Holdfeldt, A., Skovbakke, S. L., Winther, M., Gabl, M., Nielsen, C., Perez-Gassol, I., Larsen, C. J., Wang, J. M., Karlsson, A., Dahlgren, C., Forsman, H. & Franzyk, Henrik, 2016, In: Journal of Biological Chemistry. 291, 38, p. 19888-19899 12 p.

      Research output: Contribution to journalJournal articlepeer-review

    133. 2015
    134. Published

      Hyaluronic Acid-Based Nanogels Produced by Microfluidics-Facilitated Self-Assembly Improves the Safety Profile of the Cationic Host Defense Peptide Novicidin

      Water, J. J., Kim, Y., Maltesen, M. J., Franzyk, Henrik, Foged, Camilla & Nielsen, Hanne Mørck, Aug 2015, In: Pharmaceutical Research. 32, 8, p. 2727-35 9 p.

      Research output: Contribution to journalJournal articlepeer-review

    135. Published

      Conjugation of a cell-penetrating peptide to parathyroid hormone affects its structure, potency, and transepithelial permeation

      Kristensen, Mie, de Groot, A. M., Berthelsen, J., Franzyk, Henrik, Sijts, A. & Nielsen, Hanne Mørck, 18 Mar 2015, In: Bioconjugate Chemistry. 26, p. 477-488 12 p.

      Research output: Contribution to journalJournal articlepeer-review

    136. Published

      Nanoparticle-mediated delivery of the antimicrobial peptide plectasin against Staphylococcus aureus in infected epithelial cells

      Water, J. J., Smart, S., Franzyk, Henrik, Foged, Camilla & Nielsen, Hanne Mørck, 18 Feb 2015, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 92, p. 65-73 9 p.

      Research output: Contribution to journalJournal articlepeer-review

    137. Published

      End Group Modification: Efficient Tool for Improving Activity of Antimicrobial Peptide Analogues towards Gram-Positive Bacteria

      Jahnsen, R. O., Sandberg-Schaal, A., Frimodt-Møller, N., Nielsen, Hanne Mørck & Franzyk, Henrik, 23 Jan 2015, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 95, Part A, p. 40–46 7 p.

      Research output: Contribution to journalJournal articlepeer-review

    138. Published

      A palmitoylated α-peptide/β-peptoid host defense peptide mimetic with potent anti-inflammatory activity

      Skovbakke, S. L., Heegaard, P. M. H., Forsman, H., Dahlgren, C. & Franzyk, Henrik, 2015.

      Research output: Contribution to conferencePosterResearchpeer-review

    139. Published

      Antifungal properties of peptidomimetics with an arginine-[β-(2,5,7-tri-tert-butylindol-3-yl)alanine]-arginine motif against Saccharomyces cerevisiae and Zygosaccharomyces bailii

      Larsen, C. E., Larsen, C. J., Franzyk, Henrik & Regenberg, Birgitte, 2015, In: F E M S Yeast Research. 15, 3, 8 p., fov011.

      Research output: Contribution to journalJournal articlepeer-review

    140. Published

      Biophysical and nanostructural properties of trehalose 6-mono and 6,6’-diesters

      Madsen, C. M., Martin-Bertelsen, Birte, Kallerup, R. S., Rose, F., Christensen, D., Yaghmur, Anan, Franzyk, Henrik & Foged, Camilla, 2015. 1 p.

      Research output: Contribution to conferencePosterResearch

    141. Published

      Cell-penetrating antimicrobial peptides - prospectives for targeting intracellular infections

      Bahnsen, J. S., Franzyk, Henrik, Sayers, E. J., Jones, A. T. & Nielsen, Hanne Mørck, 2015, In: Pharmaceutical Research. 32, 5, p. 1546-56 11 p.

      Research output: Contribution to journalJournal articlepeer-review

    142. Published

      Influence of trehalose 6,6'-diester (TDX) chain length on the physicochemical and immunopotentiating properties of DDA/TDX liposomes

      Kallerup, R. S., Madsen, C. M., Schiøth, M. L., Franzyk, Henrik, Rose, F., Christensen, D., Korsholm, K. S. & Foged, Camilla, 2015, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 90, p. 80-89 10 p.

      Research output: Contribution to journalJournal articlepeer-review

    143. Published

      Intact penetratin metabolite permeates across Caco-2 monolayers

      Birch, D., Christensen, M. V., Stærk, Dan, Franzyk, Henrik & Nielsen, Hanne Mørck, 2015.

      Research output: Contribution to conferencePosterResearch

    144. Published

      Jagten på kongens efterfølger

      Franzyk, Henrik, Björkling, Fredrik, Nielsen, J. & Nielsen, Peter E., 2015, In: Lægemiddelforskning. 2015, p. 24-27 4 p.

      Research output: Contribution to journalJournal article

    145. Published

      Lipidated α-Peptide/β-Peptoid Hybrids with Potent Anti-inflammatory Activity

      Skovbakke, S. L., Larsen, C. J., Heegaard, P. M. H., Moesby, L. & Franzyk, Henrik, 2015, In: Journal of Medicinal Chemistry. 58, 2, p. 801-813 13 p.

      Research output: Contribution to journalJournal articlepeer-review

    146. Published

      Penetratin-Mediated Transepithelial Insulin Permeation: Importance of Cationic Residues and pH for Complexation and Permeation

      Kristensen, Mie, Franzyk, Henrik, Klausen, M. T., Iversen, A., Bahnsen, J. S., Skyggebjerg, R. B., Foderà, Vito & Nielsen, Hanne Mørck, 2015, In: A A P S Journal. 17, 5, p. 1200-1209 10 p.

      Research output: Contribution to journalJournal articlepeer-review

    147. Published

      Structure-Activity Relationship Study of Lysine-Based Antimicrobial α-Peptide/β-Peptoid Oligomers

      Molchanova, N., Hansen, Paul Robert & Franzyk, Henrik, 2015.

      Research output: Contribution to conferencePosterResearch

    148. Published

      Surface coating of siRNA-peptidomimetic nano-self-assemblies with anionic lipid bilayers: Enhanced gene silencing and reduced adversed effects in vitro

      Zeng, X., de Groot, A. M., Sijts, A., Blenke, E. O., Colombo, S., van Eden, W., Franzyk, Henrik, Nielsen, Hanne Mørck & Foged, Camilla, 2015, In: Nanoscale. 7, 46, p. 19687-19698 12 p.

      Research output: Contribution to journalJournal articlepeer-review

    149. Published

      Sustained prevention of biofilm formation on a novel silicone matrix suitable for medical devices

      Steffensen, S. L., Merete H., V., Jensen, M. G., Alm, M., Franzyk, Henrik & Nielsen, Hanne Mørck, 2015, In: European Journal of Pharmaceutics and Biopharmaceutics. 94, p. 305-311

      Research output: Contribution to journalJournal articlepeer-review

    150. Published

      The Proteolytically Stable Peptidomimetic Pam-(Lys-βNSpe)6-NH2 Selectively Inhibits Human Neutrophil Activation via Formyl Peptide Receptor 2

      Skovbakke, S. L., Heegaard, P. M. H., Larsen, C. J., Franzyk, Henrik, Forsman, H. & Dahlgren, C., 2015, In: Biochemical Pharmacology. 93, 2, p. 182-195 14 p.

      Research output: Contribution to journalJournal articlepeer-review

    151. 2014
    152. Published

      Critical role of a conserved transmembrane lysine in substrate recognition by the proton-coupled oligopeptide transporter YjdL

      Jensen, J. M., Aduri, N. G., Prabhala, B. K., Jahnsen, R., Franzyk, Henrik & Mirza, Osman Asghar, 24 Sep 2014, In: International Journal of Biochemistry & Cell Biology. 55, p. 311-17 7 p.

      Research output: Contribution to journalJournal articlepeer-review

    153. Published

      The Effects of Conformational Constraints in the Polyamine Moiety of Philanthotoxins on AMPAR Inhibition

      Franzyk, Henrik, Grzeskowiak, J. W., Tikhonov, D. B., Jaroszewski, J. W. & Mellor, I. R., Aug 2014, In: ChemMedChem. 9, 8, p. 1725-31 7 p.

      Research output: Contribution to journalJournal articlepeer-review

    154. Published

      Quantification of pharmaceutical peptides using selenium as an elemental detection label

      Møller, L. H., Gabel-Jensen, C., Franzyk, Henrik, Bahnsen, J. S., Stürup, Stefan & Gammelgaard, Bente, 16 Jul 2014, In: Metallomics : integrated biometal science. 6, p. 1639-1647 9 p.

      Research output: Contribution to journalJournal articlepeer-review

    155. Published

      Tailoring Cytotoxicity of Antimicrobial Peptidomimetics with High Activity against Multidrug-Resistant Escherichia coli

      Jahnsen, R. D., Sandberg-Schaal, A., Vissing, K. J., Nielsen, Hanne Mørck, Frimodt-Møller, N. & Franzyk, Henrik, 20 Mar 2014, In: Journal of Medicinal Chemistry. 57, 7, p. 2864-2873

      Research output: Contribution to journalJournal articlepeer-review

    156. Published

      Subunit-Dependent Inhibition of Neuronal Nicotinic Acetylcholine Receptors by Philanthotoxins

      Kachel, H. S., Franzyk, Henrik, Strømgaard, Kristian, Tikhonov, D. B. & Mellor, I. R., 28 Jan 2014, In: Biophysical Society. Annual Meeting. Abstracts. 106, 2, p. 338A-338A 1 p.

      Research output: Contribution to journalJournal article

    157. Published
    158. Published

      Human plasma potentiates antibacterial effect of peptidomimetics against Gram-negative and Gram-positive pathogenic bacteria

      Citterio, L., A, K., K, H., Franzyk, Henrik & Gram, L., 2014.

      Research output: Contribution to conferencePosterResearch

    159. Published

      Improving the safety profile of an antimicrobial peptide: Self-assembly into hydrogel nanoparticles using microfluidics

      Water, J. J., Maltesen, M. J., Foged, Camilla, Franzyk, Henrik & Nielsen, Hanne Mørck, 2014.

      Research output: Contribution to conferencePosterResearchpeer-review

    160. Published

      Prolonged Shelf Life in Fermented Milk Products Investigated by Bioassay-Guided Chemometrics

      Vinther, J. M., Garrigues, C., Nyberg, N., Jäger, A., Franzyk, Henrik & Stærk, Dan, 2014.

      Research output: Contribution to conferencePosterResearch

    161. Published

      Silicone embedded nanogels for prolonged resistance against biofilm formation

      Steffensen, S. L., Vestergaard, M. H., Jensen, M. G., Alm, M., Franzyk, Henrik & Nielsen, Hanne Mørck, 2014.

      Research output: Contribution to conferencePosterResearchpeer-review

    162. Published

      The palmitoylated α-peptide/β-peptoid hybrid Pam-(Lys-βNSpe)6-NH2 is a novel host defense peptidomimetic with potent anti-inflammatory activity

      Skovbakke, S. L., Heegaard, P. M. H., Forsman, H., Dahlgren, C. & Franzyk, Henrik, 2014.

      Research output: Contribution to conferencePosterResearch

    163. Published

      The supramolecular structure is decisive for the immunoactivity of a mycobacterial lipid in vitro.

      Martin-Bertelsen, Birte, Korsholm, K. S., Christensen, D., Franzyk, Henrik, Yaghmur, Anan & Foged, Camilla, 2014. 1 p.

      Research output: Contribution to conferencePosterResearch

    164. 2013
    165. Published

      Characterization of a proteolytically stable multifunctional host defense peptidomimetic

      Jahnsen, R. D., Haney, E. F., Franzyk, Henrik & Hancock, R. E. W., 10 Oct 2013, In: Chemistry & Biology. 20, 10, p. 1286-1295 10 p.

      Research output: Contribution to journalJournal articlepeer-review

    166. Published

      Selectivity in the potentiation of antibacterial activity of α-peptide/β-peptoid peptidomimetics and antimicrobial peptides by human blood plasma

      Hein-Kristensen, L., Knapp, K. M., Franzyk, Henrik & Gram, L., 27 Aug 2013, In: Research in Microbiology. 164, 9, p. 933-940 8 p.

      Research output: Contribution to journalJournal articlepeer-review

    167. Published

      Adaptive Evolution of Escherichia coli to an α-Peptide/β-Peptoid Peptidomimetic Induces Stable Resistance

      Hein-Kristensen, L., Franzyk, Henrik, Holch, A. & Gram, L., 2013, In: PLOS ONE. 8, 9, p. e73620

      Research output: Contribution to journalJournal articlepeer-review

    168. Published

      Antimicrobial Peptidomimetics

      Jahnsen, R. O., Frimodt-Møller, N. & Franzyk, Henrik, 2013.

      Research output: Contribution to conferencePosterResearch

    169. Published

      Antimicrobial and cell-penetrating properties of penetratin analogs: effect of sequence and secondary structure

      Bahnsen, J. S., Franzyk, Henrik, Sandberg-Schaal, A. & Nielsen, Hanne Mørck, 2013, In: B B A - Biomembranes. 1828, 2, p. 223-232 10 p.

      Research output: Contribution to journalJournal articlepeer-review

    170. Published

      Cell-penetrating Peptides Targeting Intracellular Infections

      Bahnsen, J. S., Franzyk, Henrik, Sandberg-Schaal, A. & Nielsen, Hanne Mørck, 2013.

      Research output: Contribution to conferencePosterResearchpeer-review

    171. Published

      High in vitro antimicrobial activity of ß-peptoid-peptide hybrid oligomers against planktonic and biofilm cultures of Staphylococcus epidermidis

      Liu, Y., Knapp, K. M., Yang, L., Molin, S., Franzyk, Henrik & Folkesson, A., 2013, In: International Journal of Antimicrobial Agents. 41, 1, p. 20-27 8 p.

      Research output: Contribution to journalJournal articlepeer-review

    172. Published
    173. Published

      Novel Silicone Composite for Prolonged Release of Antimicrobial Peptides

      Steffensen, S. L., Møller, E. H., Franzyk, Henrik, Jensen, M. G., Alm, M. & Nielsen, Hanne Mørck, 2013.

      Research output: Contribution to conferencePosterResearchpeer-review

    174. Published

      The supramolecular structure is decisive for the immunostimulatory properties of synthetic analogues of a mycobacterial lipid in vitro

      Martin-Bertelsen, Birte, Korsholm, K. S., Rose, F., Nordly, P. J., Franzyk, Henrik, Andersen, P., Agger, E. M., Christensen, D., Yaghmur, Anan & Foged, Camilla, 2013, In: R S C Advances. 3, 43, p. 20673-20683

      Research output: Contribution to journalJournal articlepeer-review

    175. 2012
    176. Published

      Antimicrobial activity of peptidomimetics against multidrug-resistant Escherichia coli: a comparative study of different backbones

      Jahnsen, R. D., Frimodt-Møller, N. & Franzyk, Henrik, 2012, In: Journal of Medicinal Chemistry. 55, 16, p. 7253-61 9 p.

      Research output: Contribution to journalJournal articlepeer-review

    177. Published

      Antimicrobial peptides as novel delivery vehicles for genetic antibiotics

      Seigan, G. B., Franzyk, Henrik & Nielsen, Peter E., 2012, In: Journal of Peptide Science. 18, Suppl. 1, p. S116-S117

      Research output: Contribution to journalConference abstract in journalpeer-review

    178. Published

      Antimicrobial peptides as novel delivery vehicles for genetic antibiotics

      Seigan, G. B., Franzyk, Henrik & Nielsen, Peter E., 2012. 2 p.

      Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

    179. Published

      Antimikrobielle peptider: et nyt våben mod multiresistente bakterier

      Munk, J., Hansen, Paul Robert & Franzyk, Henrik, 2012, In: Lægemiddelforskning. 2012, p. 9-11

      Research output: Contribution to journalJournal article

    180. Published
    181. Published

      Håb om at ramme latente bakterier i deres skjul

      Bahnsen, J. S., Water, J. J., Foged, Camilla, Franzyk, Henrik & Nielsen, Hanne Mørck, 2012, In: Lægemiddelforskning 2012. 2012, p. 12-14

      Research output: Contribution to journalJournal article

    182. Published

      Induction of antimicrobial activity against ESBL and NDM-1 producing Escherichia coli by peptide backbone modifications - a comparative study

      Jahnsen, R. O., Frimodt-Møller, N. & Franzyk, Henrik, 2012.

      Research output: Contribution to conferencePosterResearch

    183. Published

      Interaction of peptidomimetics with bilayer membranes: biophysical characterization and cellular uptake

      Jing, X., Kasimova, M. R., Simonsen, A. H., Jørgensen, Lene, Malmsten, M., Franzyk, Henrik & Foged, Camilla, 2012, In: Langmuir. 28, 11, p. 5167-5175

      Research output: Contribution to journalJournal articlepeer-review

    184. Published

      Membrane adsorption and binding, cellular uptake and cytotoxicity of cell-penetrating peptidomimetics with α-peptide/β-peptoid backbone: effects of hydrogen bonding and α-chirality in the β-peptoid residues

      Jing, X., Yang, M., Kasimova, M. R., Malmsten, M., Franzyk, Henrik, Jørgensen, Lene, Foged, Camilla & Nielsen, Hanne Mørck, 2012, In: BBA General Subjects. 1818, 11, p. 2660-2668 9 p.

      Research output: Contribution to journalJournal articlepeer-review

    185. Published

      Solid-phase route to Fmoc-protected cationic amino acid building blocks

      Clausen, J. D., Linderoth, L., Nielsen, Hanne Mørck & Franzyk, Henrik, 2012, In: Amino Acids. 43, 4, p. 1633-41 9 p.

      Research output: Contribution to journalJournal articlepeer-review

    186. Published

      The antimicrobial and cell-penetrating effects of the CPP penetratin and derived analogues.

      Bahnsen, J. S., Franzyk, Henrik & Nielsen, Hanne Mørck, 2012.

      Research output: Contribution to conferencePosterResearch

    187. 2011
    188. Published

      Bacterial membrane activity of alpha-peptide/beta-peptoid chimeras: influence of amino acid composition and chain length on the activity against different bacterial strains

      Hein-Kristensen, L., Knapp, K. M., Franzyk, Henrik & Gram, L., 22 Jun 2011, In: B M C Microbiology. 11, 1, p. 144

      Research output: Contribution to journalJournal articlepeer-review

    189. Published

      Incorporation of a synthetic mycobacterial monomycoloyl glycerol analogue stabilizes dimethyldioctadecylammonium liposomes and potentiates their adjuvant effect in vivo

      Nordly, P. J., Korsholm, K. S., Pedersen, E. A., Khilji, T. S., Franzyk, Henrik, Jørgensen, Lene, Nielsen, Hanne Mørck, Agger, E. M. & Foged, Camilla, 2011, In: European Journal of Pharmaceutics and Biopharmaceutics. 77, 1, p. 89-98

      Research output: Contribution to journalJournal articlepeer-review

    190. 2010
    191. Published

      Erratum: Aminolysis of resin-bound N-nosylaziridine-2-carboxylic acids (Organic Letters (2006) 8 (3371))

      Olsen, Christian Adam, Christensen, C., Nielsen, Birgitte, Farah, M. M., Witt, M., Clausen, Rasmus Prætorius, Kristensen, Jesper Langgaard, Franzyk, Henrik & Jaroszewski, J. W., 15 Oct 2010, In: Organic Letters. 12, 20, p. 4708 1 p.

      Research output: Contribution to journalComment/debatepeer-review

    192. Published

      Antimicrobial, hemolytic, and cytotoxic activities of β-peptoid- peptide hybrid oligomers: Improved properties compared to natural AMPs (ChemBioChem (2010) 11, (152-160))

      Olsen, Christian Adam, Ziegler, H. L., Nielsen, Hanne Mørck, Frimodt-Møller, N., Jaroszewski, J. W. & Franzyk, Henrik, 16 Aug 2010, In: ChemBioChem. 11, 12, 1 p.

      Research output: Contribution to journalComment/debatepeer-review

    193. Published

      A synthetic mycobacterial monomycoloyl glycerol analogue stabilizes DDA liposomes

      Nordly, P. J., Pedersen, E. A., Khiljii, T. S., Agger, E. M., Jørgensen, Lene, Nielsen, Hanne Mørck, Korsholm, K. S., Franzyk, Henrik & Foged, Camilla, 2010, In: CRS Newsletter. 27, 2, p. 12 14 p.

      Research output: Contribution to journalJournal article

    194. Published

      Antimicrobial, hemolytic, and cytotoxic activities of ß-peptoid-peptide hybrid oligomers: Improved properties compared to natural AMPs

      Olsen, Christian Adam, Ziegler, H. L., Nielsen, Hanne Mørck, Frimodt-Møller, N., Jaroszewski, J. W. & Franzyk, Henrik, 2010, In: ChemBioChem. 11, 10, p. 1356-1360

      Research output: Contribution to journalJournal articlepeer-review

    195. Published

      Assessment of structurally diverse philanthotoxin analogues for inhibitory activity on ionotropic glutamate receptor subtypes: Discovery of nanomolar, nonselective, and use-dependent antagonists

      Frølund, S., Bella, A., Kristensen, Anders Skov, Ziegler, H. L., Witt, M., Olsen, C. A., Strømgaard, Kristian, Franzyk, Henrik & Jaroszewski, J. W., 2010, In: Journal of Medicinal Chemistry. 53, 20, p. 7441-7451

      Research output: Contribution to journalJournal articlepeer-review

    196. Published

      Comparison of synthesis and antibacterial activity of a- and ß-peptoids

      Knapp, K. M., Franzyk, Henrik & Jahnsen, R., 2010. 1 p.

      Research output: Contribution to conferencePosterResearchpeer-review

    197. Published

      Linking activity and mode of action to length in a novel peptidomimetics library

      Hein-Kristensen, L., Franzyk, Henrik & Gram, L., 2010.

      Research output: Contribution to conferencePosterResearch

    198. Published

      Microcalorimetric and spectroscopic studies on the mechanism of interaction between novel peptidomimetics and lipid bilayers

      Nielsen, Hanne Mørck, Jing, X., Simonsen, A., Kasimova, M. R., Malmsten, M., Franzyk, Henrik & Foged, Camilla, 2010, In: Journal of Peptide Science. 16, s1, p. 151 1 p.

      Research output: Contribution to journalConference abstract in journal

    199. Published

      Microcalorimetric and spectroscopic studies on the mechanism of interaction between novel peptoids and lipid bilayers - effect of length, charge and N-terminal end group

      Jing, X., Simonsen, A. H., Kasimova, M. R., Franzyk, Henrik, Foged, Camilla & Nielsen, Hanne Mørck, 2010, In: Drug Discovery Today. 15, 23/24, p. 1109

      Research output: Contribution to journalConference abstract in journal

    200. Published

      Ring opening of a Resin-bound chiral aziridine with phenols

      Ottesen, L. K., Jaroszewski, J. W. & Franzyk, Henrik, 2010, In: Synfacts. 2010, 11, p. 1319 1 p.

      Research output: Contribution to journalJournal article

    201. Published

      Ring opening of a resin-bound chiral aziridine with phenol nucleophiles

      Ottesen, L. K., Jaroszewski, J. W. & Franzyk, Henrik, 2010, In: Journal of Organic Chemistry. 75, 15, p. 4983-4991

      Research output: Contribution to journalJournal articlepeer-review

    202. Published

      Studies towards improved cell-penetrating peptide-promoted macromolecular drug delivery

      Dahlqvist Clausen, J. A., Linderoth, L., Andersen, R. B., Franzyk, Henrik & Nielsen, Hanne Mørck, 2010, In: Drug Discovery Today. 15, 23-24, p. 1109 1 p., A81.

      Research output: Contribution to journalConference abstract in journal

    203. Published

      Studies towards improved stability and permeability of a cell-penetrating peptide

      Dahlqvist Clausen, J. A., Linderoth, L., Andersen, R. B., Franzyk, Henrik & Nielsen, Hanne Mørck, 2010, In: Journal of Peptide Science. 16, p. 148 1 p.

      Research output: Contribution to journalConference abstract in journal

    204. 2009
    205. Published

      Expedite Protocol for Construction of Chiral Regioselectively N-Protected Monosubstituted Piperazine, 1,4-Diazepane, and 1,4-Diazocane Building Blocks

      Crestey, F., Witt, M., Jaroszewski, J. W. & Franzyk, Henrik, 11 Jun 2009, In: Journal of Organic Chemistry. 74, 15, p. 5652-5655

      Research output: Contribution to journalJournal articlepeer-review

    206. Published

      Selectively N-protected enantiopure 2,5-disubstituted piperazines: Avoiding the pitfalls in solid-phase Fukuyama-Mitsunobu cyclizations

      Ottesen, L. K., Olsen, Christian Adam, Witt, M., Jaroszewski, J. W. & Franzyk, Henrik, 2009, In: Chemistry: A European Journal. 15, 12, p. 2966-2978

      Research output: Contribution to journalJournal articlepeer-review

    207. 2008
    208. Published

      Cellular uptake and membrane-destabilising properties of a-peptide/ß-peptoid chimeras: lessons for the design of new cell-penetrating peptides

      Foged, Camilla, Franzyk, Henrik, Bahrami, S., Frøkjær, Sven, Jaroszewski, J. W., Nielsen, Hanne Mørck & Olsen, Christian Adam, 2008, In: BBA General Subjects. 1778, 11, p. 2487-2495

      Research output: Contribution to journalJournal articlepeer-review

    209. Published

      Dimeric Building Blocks for Solid-Phase Synthesis of α-Peptide-β-Peptoid Chimeras

      Seigan, G. B., Vedel, L., Matthias, W., Jaroszewski, J. W., Olsen, Christian Adam & Franzyk, Henrik, 2008, In: Synthesis. 2008, 15, p. 2381-2390 10 p.

      Research output: Contribution to journalJournal articlepeer-review

    210. Published

      Efficient loading of primary alcohols onto a solid phase using a trityl bromide linker

      Crestey, F., Ottesen, L. K., Jaroszewski, J. W. & Franzyk, Henrik, 2008, In: Tetrahedron Letters. 49, 41, p. 5890-5893

      Research output: Contribution to journalJournal articlepeer-review

    211. Published

      Electrophysiological characterization of analogues of philanthotoxin-343 on ionotropic glutamate receptors

      Frølund, S. U., Ziegler, H. L., Franzyk, Henrik, Strømgaard, Kristian, Kristensen, Anders Skov & Jaroszewski, J. W., 2008.

      Research output: Contribution to conferencePosterResearch

    212. Published

      Lægemidler fra naturstoffer: fortid eller fremtid?

      Jaroszewski, J. W., Christensen, Søren Brøgger, Franzyk, Henrik, Stærk, Dan & Ziegler, H., 2008, In: Lægemiddelforskning. p. 4-6

      Research output: Contribution to journalJournal article

    213. Published

      Microwave-Assisted Ring-Opening of Activated Aziridines with Resin-Bound Amines

      Franzyk, Henrik, Crestey, F., Witt, M., Frydenvang, Karla Andrea, Stærk, Dan & Jaroszewski, J., 2008, In: Synfacts. 7, p. 769

      Research output: Contribution to journalJournal articlepeer-review

    214. Published

      Microwave-assisted ring-opening of activated aziridines with resin-bound amines

      Crestey, F., Witt, M., Frydenvang, Karla Andrea, Stærk, Dan, Jaroszewski, J. W. & Franzyk, Henrik, 2008, In: Journal of Organic Chemistry. 73, 9, p. 3566-3569 4 p.

      Research output: Contribution to journalJournal articlepeer-review

    215. Published

      Solid-phase peptide synthesis and circular dichroism study of chiral ß-peptoid homooligomers

      Olsen, Christian Adam, Lambert, M., Witt, M., Franzyk, Henrik & Jaroszewski, J. W., 2008, In: Amino Acids. 34, 3, p. 465-471

      Research output: Contribution to journalJournal articlepeer-review

    216. 2007
    217. Published

      Antiplasmodial and prehemolytic activities of alpha-peptide-beta-peptoid chimeras

      Vedel, L., Bonke, G., Foged, Camilla, Ziegler, H. L., Franzyk, Henrik, Jaroszewski, J. W. & Olsen, Christian Adam, 2007, In: ChemBioChem. 8, 15, p. 1781-1784 4 p.

      Research output: Contribution to journalJournal articlepeer-review

    218. Published

      Aziridines in parallel- and solid-phase synthesis

      Olsen, Christian Adam, Bonke, G., Vedel, L., Franzyk, Henrik & Jaroszewski, J. W., 2007, In: European Journal of Organic Chemistry. 2007, 11, p. 1717-1724

      Research output: Contribution to journalReviewpeer-review

    219. Published

      Noter til bioorganisk kemi M23-1

      Franzyk, Henrik, Christensen, Søren Brøgger & Jaroszewski, J. W., 2007, København: Københavns Universitet, Det Farmaceutiske Fakultet, Institut for Medicinalkemi.

      Research output: Book/ReportCompendium/lecture notes

    220. Published

      Solid-phase synthesis of neuroactive spider-wasp hybrid toxin analogues using a backbone amide linker

      Olsen, Christian Adam, Witt, M., Franzyk, Henrik & Jaroszewski, J. W., 2007, In: Tetrahedron Letters. 48, 3, p. 405-408

      Research output: Contribution to journalJournal articlepeer-review

    221. Published

      Øvelsesvejledning til bioorganisk kemi: øvelser M23-2

      Franzyk, Henrik, 2007, Københavns Universitet, Det Farmaceutiske Fakultet, Institut for Medicinalkemi.

      Research output: Book/ReportCompendium/lecture notes

    222. Published

      α-Peptide/ß-Peptoid Chimeras

      Olsen, Christian Adam, Bonke, G., Vedel, L., Adsersen, A., Witt, M., Franzyk, Henrik & Jaroszewski, J. W., 2007, In: Organic Letters. 9, 8, p. 1549–1552 4 p.

      Research output: Contribution to journalJournal articlepeer-review

    223. 2006
    224. Published

      Aminolysis of resin-bound N-nosylaziridine-2-carboxylic acids

      Olsen, Christian Adam, Christensen, C., Nielsen, Birgitte, Farah, M. M., Mohamed, F. M., Witt, M., Clausen, Rasmus Prætorius, Kristensen, Jesper Langgaard, Franzyk, Henrik & Jaroszewski, J. W., 2006, In: Organic Letters. 8, 15, p. 3371-4 4 p.

      Research output: Contribution to journalJournal articlepeer-review

    225. Published

      Kunstige forsvarspeptider

      Olsen, Christian Adam, Franzyk, Henrik & Jaroszewski, J. W., 2006, In: Lægemiddelforskning. p. 18-19 2 p.

      Research output: Contribution to journalJournal article

    226. Published

      Nanomolær inhibering med hvepsetoksinanaloger – syntese og elektrofysiologi

      Olsen, Christian Adam, Franzyk, Henrik & Jaroszewski, J. W., 2006, In: Dansk Kemi. 87, p. 23-26 4 p.

      Research output: Contribution to journalJournal article

    227. Published

      Protolytic properties of polyamine wasp toxin analogues studied by 13C NMR spectroscopy

      Strømgaard, Kristian, Piazzi, L., Olsen, Christian Adam, Franzyk, Henrik & Jaroszewski, J. W., 2006, In: Magnetic Resonance in Chemistry. 44, 11, p. 1013-22 10 p.

      Research output: Contribution to journalJournal articlepeer-review

    228. Published

      Tuning wasp toxin structure for nicotinic receptor antagonism: cyclohexylalanine-containing analogues as potent and voltage-dependent blockers

      Olsen, Christian Adam, Mellor, I. R., Wellendorph, Petrine, Usherwood, P. N. R., Witt, M., Franzyk, Henrik & Jaroszewski, J. W., 2006, In: ChemMedChem. 1, 3, p. 303-5 3 p.

      Research output: Contribution to journalJournal articlepeer-review

    229. 2005
    230. Published

      Erratum: "Naravelia zeylanica: Occurrence of primary benzamides in flowering plants" (Natural Product Research vol. 19 (3) (291-294))

      Jaroszewski, J. W., Stærk, Dan, Holm-Møller, S. B., Jensen, T. H., Franzyk, Henrik & Somanadhan, B., 1 Jun 2005, In: Natural Product Research. 19, 4, 1 p.

      Research output: Contribution to journalComment/debatepeer-review

    231. Published

      Naravelia zeyanica: occurrence of primary benzamides in flowering plants

      Jaroszewski, J. W., Stærk, Dan, Holm-Møller, S. B., Jensen, T. H. & Franzyk, Henrik, 2005, In: Natural Product Research. 19, 3, p. 291-294

      Research output: Contribution to journalJournal articlepeer-review

    232. Published

      Fukuyama-Mitsunobu Alkylation in Amine Synthesis on Solid Phase Revisited: N-Alkylation with Secondary Alcohols and Synthesis of Curtatoxins

      Olsen, Christian Adam, Witt, M., Hansen, S. H., Jaroszewski, J. W. & Franzyk, Henrik, 2005, In: Tetrahedron. 61, p. 6046-6055 10 p.

      Research output: Contribution to journalJournal articlepeer-review

    233. Published

      N-Alkylation Reactions and Indirect Formation of Amino Functionalities in Solid-Phase Synthesis

      Olsen, Christian Adam, Jaroszewski, J. W. & Franzyk, Henrik, 2005, In: Synthesis. p. 2631-2653 23 p.

      Research output: Contribution to journalReviewpeer-review

    234. Published

      New Linker Strategies in SPS of Neuroactive Wasp Toxin Analogues

      Olsen, Christian Adam, Jaroszewski, J. W. & Franzyk, Henrik, 2005.

      Research output: Contribution to conferencePosterResearch

    235. Published

      On-Resin Carboxy Group Activation of ω-Amino Acids in Solid-Phase Synthesis­ of Philanthotoxin Analogues

      Franzyk, Henrik, Jørgensen, M. R., Jaroszewski, J. W. & Witt, M., 2005, In: Synthesis.

      Research output: Contribution to journalJournal articlepeer-review

    236. Published

      On-resin Carboxy Group Activation of ω-Amino Acids in Solid-Phase Synthesis of Philanthotoxin Analogues

      Jørgensen, M. R., Jaroszewski, J. W., Witt, M. & Franzyk, Henrik, 2005, In: Synthesis. p. 2687-2694 8 p.

      Research output: Contribution to journalJournal articlepeer-review

    237. Published

      Side-chain-anchored N(alpha)-Fmoc-Tyr-OPfp for bidirectional solid-phase synthesis

      Olsen, Christian Adam, Jørgensen, M., Hansen, S. H., Witt, M., Jaroszewski, J. W. & Franzyk, Henrik, 2005, In: Organic Letters. 7, 9, p. 1703-6 4 p.

      Research output: Contribution to journalJournal articlepeer-review

    238. Published

      The effects of conformational constraints and steric bulk in the amino acid moiety of philanthotoxins on AMPAR antagonism

      Jørgensen, M., Olsen, Christian Adam, Mellor, I. R., Usherwood, P. N. R., Witt, M., Franzyk, Henrik & Jaroszewski, J. W., 2005, In: Journal of Medicinal Chemistry. 48, 1, p. 56-70 15 p.

      Research output: Contribution to journalJournal articlepeer-review

    239. 2004
    240. Published

      Cyclopentanoid cyanohydrin glucosides from Passiflora mixta

      Bylov, T., Franzyk, Henrik & Jaroszewski, J. W., 2004, In: Biochemical Systematics and Ecology. 32, p. 695-698 4 p.

      Research output: Contribution to journalJournal articlepeer-review

    241. Published

      Diols as Building Blocks in Solid-Phase Synthesis of Polyamine Toxins by Fukuyama-Mitsunobu Alkylation

      Olsen, Christian Adam, Witt, M., Jaroszewski, J. W. & Franzyk, Henrik, 2004, In: Synlett : Accounts and Rapid Communications in Synthetic Organic Chemistry. p. 473-476 4 p.

      Research output: Contribution to journalJournal articlepeer-review

    242. Published

      Dopaol 2-keto- and 2,3-diketoglycosides from Chelone obliqua

      Franzyk, Henrik, Olsen, C. E. & Jensen, Søren, 2004, In: Journal of Natural Products. 67, 6, p. 1052-4 3 p.

      Research output: Contribution to journalJournal articlepeer-review

    243. Published

      Erythrocyte membrane modifying agents and the inhibition of Plasmodium falciparum growth: structure-activity relationships for betulinic acid analogues

      Ziegler, H. L., Franzyk, Henrik, Sairafianpour, M., Tabatabai, M., Tehrani, M. D., Bagherzadeh, K., Hägerstrand, H., Stærk, Dan & Jaroszewski, J. W., 2004, In: Bioorganic & Medicinal Chemistry. 12, p. 119-127

      Research output: Contribution to journalJournal articlepeer-review

    244. Published

      Expedient protocol for solid-phase synthesis of secondary and tertiary amines

      Olsen, Christian Adam, Witt, M., Jaroszewski, J. W. & Franzyk, Henrik, 2004, In: Organic Letters. 6, 12, p. 1935-8 4 p.

      Research output: Contribution to journalJournal articlepeer-review

    245. Published

      Solid-phase synthesis of rigid acylpolyamines using temporary N-4,4'-dimethoxytrityl protection in the presence of trityl linkers

      Olsen, Christian Adam, Witt, M., Jaroszewski, J. W. & Franzyk, Henrik, 2004, In: Journal of Organic Chemistry. 69, 18, p. 6149-52 4 p.

      Research output: Contribution to journalJournal articlepeer-review

    246. 2003
    247. Published

      A sequential high-yielding large-scale solution-method for synthesis of philanthotoxin analogues

      Wellendorph, Petrine, Jaroszewski, J. W., Hansen, S. H. & Franzyk, Henrik, 2003, In: European Journal of Medicinal Chemistry. 38, 1, p. 117-22 6 p.

      Research output: Contribution to journalJournal articlepeer-review

    248. Published

      Chemotaxonomy and Evolution of Plantago L

      Rønsted, Nina, Mølgaard, Per, Franzyk, Henrik, Jaroszewski, J. W. & Jensen, S. R., 2003, In: Plant Systematics and Evolution. 242, p. 63-82 20 p.

      Research output: Contribution to journalJournal articlepeer-review

    249. Published

      Hurtige genveje til nye lægemidler

      Olsen, Christian Adam, Franzyk, Henrik & Jaroszewski, J. W., 2003, In: Lægemiddelforskning. 2003, p. 8-9 2 p.

      Research output: Contribution to journalJournal article

    250. Published

      New Efficient SN2 Protocol for the Synthesis of Polyamine Toxins on Solid Phase

      Olsen, Christian Adam, Jaroszewski, J. W. & Franzyk, Henrik, 2003.

      Research output: Contribution to conferencePosterResearch

    251. Published

      Solid-phase Synthesis of Philanthotoxin Analogues with Modified and Elongated Polyamine Chains

      Jørgensen, M. R., Jaroszewski, J. W. & Franzyk, Henrik, 2003.

      Research output: Contribution to conferencePosterResearch

    252. Published

      Solid-phase polyamine synthesis using piperazine and piperidine building blocks

      Olsen, Christian Adam, Witt, M., Jaroszewski, J. W. & Franzyk, Henrik, 2003, In: Organic Letters. 5, 22, p. 4183-5 3 p.

      Research output: Contribution to journalJournal articlepeer-review

    253. Published

      The Choice of Phosphane Reagent in Fukuyama-Mitsunobu Alkylation: Intramolecular Selectivity Between Primary and Secondary Alcohols in the Preparation of Asymmetric Tetraamine Building Blocks for Synthesis of Philanthotoxins

      Olsen, Christian Adam, Jørgensen, M. R., Witt, M., Mellor, I. R., Usherwood, P. N. R., Jaroszewski, J. W. & Franzyk, Henrik, 2003, In: European Journal of Organic Chemistry. p. 3288-3299 12 p.

      Research output: Contribution to journalJournal articlepeer-review

    254. 2002
    255. Published

      Incorporation of the crossfire Beilstein database into the organic chemistry curriculum at the Royal Danish School of Pharmacy

      Christensen, Søren Brøgger, Franzyk, Henrik, Frølund, Bente, Jaroszewski, J. W., Stærk, Dan & Vedsø, P., 1 Jun 2002, In: Journal of Chemical Education. 79, 6, 1 p.

      Research output: Contribution to journalJournal articlepeer-review

    256. Published

      SYNTHESIS OF NOVEL HYDROXYMETHYL SUBSTITUTED ANALOGUES RELATED TO CARBOVIR AND NEPLANOCIN A

      Franzyk, Henrik, Jensen, S. R., Olsen, C. E. & Rasmussena, J. H., Apr 2002, In: Nucleosides, Nucleotides and Nucleic Acids.

      Research output: Contribution to journalJournal articlepeer-review

    257. Chemotaxonomy of the Oleaceae: iridoids as taxonomic markers

      Jensen, S. R., Franzyk, Henrik & Wallander, E., 2002, In: Phytochemistry. 60, 3, p. 213-31 19 p.

      Research output: Contribution to journalJournal articlepeer-review

    258. Published

      Cyanohydrin glycosides of Passiflora: distribution pattern, a saturated cyclopentane derivative from P. guatemalensis, and formation of pseudocyanogenic alpha-hydroxyamides as isolation artefacts

      Jaroszewski, J. W., Olafsdottir, E. S., Wellendorph, Petrine, Christensen, J. L., Franzyk, Henrik, Somanadhan, B., Budnik, B. A., Jørgensen, L. B. & Clausen, V., 2002, In: Phytochemistry. 59, 5, p. 501-11 11 p.

      Research output: Contribution to journalJournal articlepeer-review

    259. Published

      Incorporation of the Cross Fire Beilstein database in the organic chemistry curriculum at the Royal Danish School of Pharmacy

      Christensen, Søren Brøgger, Franzyk, Henrik, Frølund, Bente, Jaroszewski, J. W., Stærk, Dan & Vedsø, P., 2002, In: Journal of Chemical Education. 79, p. 765-768

      Research output: Contribution to journalJournal article

    260. Published

      Philanthotoxin Analogues Containing Novel Polyamine Moieties

      Olsen, Christian Adam, Jaroszewski, J. W. & Franzyk, Henrik, 2002.

      Research output: Contribution to conferencePosterResearch

    261. Published

      Solution and Solid-Phase Synthesis of Philanthotoxin Analogues

      Jørgensen, M. R., Jaroszewski, J. W. & Franzyk, Henrik, 2002.

      Research output: Contribution to conferencePosterResearch

    262. Synthesis of novel hydroxymethyl substituted analogues related to carbovir and neplanocin A

      Franzyk, Henrik, Jensen, S. R., Olsen, C. E. & Rasmussen, J. H., 2002, In: Nucleosides, Nucleotides and Nucleic Acids. 21, 1, p. 23-43 21 p.

      Research output: Contribution to journalJournal articlepeer-review

    263. 2001
    264. Published

      Iridoid Glucosides from Myxopyrum s milacifolium

      Franzyk, Henrik, Jensen, S. R. & Olsen, C. E., May 2001, In: Journal of Natural Products.

      Research output: Contribution to journalJournal articlepeer-review

    265. Iridoid glucosides from Myxopyrum smilacifolium

      Franzyk, Henrik, Jensen, S. R. & Olsen, C. E., 2001, In: Journal of Natural Products. 64, 5, p. 632-3 2 p.

      Research output: Contribution to journalJournal articlepeer-review

    266. 2000
    267. Published

      A 9-Hydroxyiridoid Isolated fromJunellia seriphioides(Verbenaceae)

      Franzyk, Henrik, Jensen, S. R., Olsen, C. E. & Quiroga, J. M., Mar 2000, In: Organic Letters.

      Research output: Contribution to journalJournal articlepeer-review

    268. Published

      A 9-Hydroxyiridoid Isolated from Junellia seriphioides (Verbenaceae)

      Franzyk, Henrik, Jensen, S. R., Olsen, C. E. & Quiroga, J. M., 2000, In: Organic Letters. 2, p. 699-700 2 p.

      Research output: Contribution to journalJournal articlepeer-review

    269. Chemotaxonomy of Plantago. Iridoid glucosides and caffeoyl phenylethanoid glycosides

      Rønsted, N., Gøbel, E., Franzyk, Henrik, Jensen, S. R. & Olsen, C. E., 2000, In: Phytochemistry. 55, 4, p. 337-48 12 p.

      Research output: Contribution to journalJournal articlepeer-review

    270. Conversion of the iridoid glucoside antirrhinoside into 3-azabicyclo[3.3.0]octane building blocks

      Franzyk, Henrik, Frederiksen, S. M. & Jensen, S. R., 2000, In: Journal of Natural Products. 63, 5, p. 592-5 4 p.

      Research output: Contribution to journalJournal articlepeer-review

    271. Iridoid Glucosides from Phlomis tuberosa L. and Phlomis herba-ventis L

      Alipieva, K. I., Jensen, S. R., Franzyk, Henrik, Handjieva, N. V. & Evstatieva, L. N., 2000, In: Zeitschrift für Naturforschung C - A Journal of Biosciences. 55c, p. 137-140 4 p.

      Research output: Contribution to journalJournal articlepeer-review

    272. Published

      Moderne naturstofkemi: effektiv analyse af naturens stofbiblioteker

      Stærk, Dan, Lemmich, E., Franzyk, Henrik, Lemmich, J. & Jaroszewski, J. W., 2000, In: Lægemiddelforskning. p. 6-7

      Research output: Contribution to journalJournal article

    273. Synthetic aspects of iridoid chemistry

      Franzyk, Henrik, 2000, In: Fortschritte der Chemie Organischer Naturstoffe. 79, p. 1-114 114 p.

      Research output: Contribution to journalReview

    274. 1999
    275. Halohydrins and Polyols Derived from Antirrhinoside: Structural Revision of Muralioside and Epimuralioside

      Franzyk, Henrik, Jensen, S. R., Thale, Z. & Olsen, C. E., 1999, In: Journal of Natural Products. 62, p. 275-278 4 p.

      Research output: Contribution to journalJournal articlepeer-review

    276. Published

      Stereoselective Hydrogenation and Ozonolysis of Iridoids. Conversion into Carbocyclic Nucleoside Analogues

      Franzyk, Henrik & Stermitz, F. R., 1999, In: Journal of Natural Products. 62, p. 1646-1654 9 p.

      Research output: Contribution to journalJournal articlepeer-review

    277. Published

      UV-guided Isolation of Verrucine A and B, novel Quinazolines from Penicillium verrucosum Structurally Related to Anacine from P. aurantiogriseum

      Larsen, T. O., Franzyk, Henrik & Jensen, S. R., 1999, In: Journal of Natural Products. 62, 11, p. 1578-1580 3 p.

      Research output: Contribution to journalJournal articlepeer-review

    278. 1998
    279. Published

      Synthesis of Antirrhinolide, a New Lactone fromAntirrhinum Majus

      Franzyk, Henrik, Frederiksen, S. M. & Jensen, S. R., Aug 1998, In: European Journal of Organic Chemistry.

      Research output: Contribution to journalJournal articlepeer-review

    280. Published

      A caffeoyl phenylethanoid glycoside from plantago myosuros

      Franzyk, Henrik, Husum, T. L. & Jensen, S. R., 1998, In: Phytochemistry. 47, 6, p. 1161-1162 2 p.

      Research output: Contribution to journalJournal articlepeer-review

    281. Iridoid Glucosides from Penstemon secundiflorus and P. grandiflorus: Revised Structure of 10-hydroxy-8-epihastatoside

      Franzyk, Henrik, Stermitz, F. R. & Jensen, S. R., 1998, In: Phytochemistry. 49, p. 2025-2030 6 p.

      Research output: Contribution to journalJournal articlepeer-review

    282. Iridoid Glycoside Biosynthesis in Penstemon Secundiflorus. Another H-5,H-9 Trans-Iridoid Glycoside

      Krull, R. E., Stermitz, F. R., Franzyk, Henrik & Jensen, S. R., 1998, In: Phytochemistry. 49, p. 1605-1608 4 p.

      Research output: Contribution to journalJournal articlepeer-review

    283. Ozonolysis of Protected Iridoid Glucosides

      Franzyk, Henrik, Rasmussen, J. H. & Jensen, S. R., 1998, In: European Journal of Organic Chemistry. p. 365-370 6 p.

      Research output: Contribution to journalJournal articlepeer-review

    284. Synthesis of Antirrhinolide, a New Lactone from Antirrhinum majus

      Franzyk, Henrik, Frederiksen, S. M. & Jensen, S. R., 1998, In: European Journal of Organic Chemistry. p. 1665-1667 3 p.

      Research output: Contribution to journalJournal articlepeer-review

    285. Synthesis of Carbocyclic Homo-N-nucleosides from Iridoids

      Franzyk, Henrik, Rasmussen, J. H., Mazzei, R. A. & Jensen, S. R., 1998, In: European Journal of Organic Chemistry. p. 2931-2935 5 p.

      Research output: Contribution to journalJournal articlepeer-review

    286. 1997
    287. Constrained Glycopeptide Ligands for MPRs. Limitations of Unprotected Phosphorylated Building Blocks

      Franzyk, Henrik, Christensen, M. K., Jørgensen, R. M., Meldal, M., Cordes, H., Mouritsen, S. & Bock, K., 1997, In: Bioorganic and Medicinal Chemistry. 5, p. 21-40 20 p.

      Research output: Contribution to journalJournal articlepeer-review

    288. Published

      Iridoid Glucosides from Picconia excelsa

      Damtoft, S., Franzyk, Henrik & Jensen, S. R., 1997, In: Phytochemistry. 45, p. 743-750 8 p.

      Research output: Contribution to journalJournal articlepeer-review

    289. Recent techniques in Glycopeptide synthesis and biology: the glycopeptide templates

      Meldal, M., Franzyk, Henrik, Meinjohanns, E., Vargas-Berenguel, A., Frische, K., Christensen, M. K., Christensen, I. B., Jensen, K. J. & Bock, K., 1997, Innovations and Perspectives in Solid Phase Synthesis & Combinatorial Libraries. Kingswinford: Mayflower Scientific, p. 263-268 6 p.

      Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

    290. Synthesis of Monoterpene Piperidines from the Iridoid Glucoside Antirrhinoside

      Franzyk, Henrik, Frederiksen, S. M. & Jensen, S. R., 1997, In: Journal of Natural Products. 60, p. 1012-1016 5 p.

      Research output: Contribution to journalJournal articlepeer-review

    291. 1996
    292. Glycopeptide Mimics of Mammalian Man9GlcNAc2. Ligand Binding to Mannan Binding Proteins (MBPs)

      Franzyk, Henrik, Meldal, M., Paulsen, H., Thiel, S., Jensenius, J. C. & Bock, K., 1996, In: Bioorganic and Medicinal Chemistry. 4, p. 1881-1899 19 p.

      Research output: Contribution to journalJournal articlepeer-review

    293. Multiple Column Synthesis of Glycopeptide Libraries in the Characterization of Receptor Interaction with Glycopeptide Ligands

      Meldal, M., Frische, K., Meinjohanns, E., Christensen, M. K., Franzyk, Henrik, Jensen, T., Werdelin, O., Galli-Stampino, L., Mouritsen, S. & Cordes, H., 1996, In: Abstract Papers Am. Chem. Soc.. 212, p. 26-ORGN

      Research output: Contribution to journalJournal article

    294. 1995
    295. Biosynthesis of Iridoids in Syringa and Fraxinus: Carbocyclic Iridoid Precursors

      Damtoft, S., Franzyk, Henrik & Jensen, S. R., 1995, In: Phytochemistry. 40, p. 785-792 8 p.

      Research output: Contribution to journalJournal articlepeer-review

    296. Biosynthesis of Iridoids in Syringa and Fraxinus: Secoiridoid Precursors

      Damtoft, S., Franzyk, Henrik & Jensen, S. R., 1995, In: Phytochemistry. 40, p. 773-784 12 p.

      Research output: Contribution to journalJournal articlepeer-review

    297. Published

      Synthesis of aliphatic O-dimannosyl amino acid building blocks for solid-phase assembly of glycopeptide libraries

      Franzyk, Henrik, Meldal, M., Paulsen, H. & Bock, K., 1995, In: Journal of the Chemical Society, Perkin Transactions 1. 36, 9, p. 2883-2898 16 p.

      Research output: Contribution to journalJournal articlepeer-review

    298. 1994
    299. Biosynthesis of Iridoids in Forsythia spp.

      Damtoft, S., Franzyk, Henrik & Jensen, S. R., 1994, In: Phytochemistry. 37, p. 173-178 6 p.

      Research output: Contribution to journalJournal articlepeer-review

    300. Biosynthesis of Secoiridoids in Fontanesia

      Damtoft, S., Franzyk, Henrik & Jensen, S. R., 1994, In: Phytochemistry. 38, p. 615-621 7 p.

      Research output: Contribution to journalJournal articlepeer-review

    301. Fontanesioside and 5-Hydroxysecologanol from Fontanesia phillyreoides.

      Damtoft, S., Franzyk, Henrik & Jensen, S. R., 1994, In: Phytochemistry. 35, p. 705-711 7 p.

      Research output: Contribution to journalJournal articlepeer-review

    302. 1993
    303. Published
    304. Biosynthesis of Secoiridoid Glucosides in Oleaceae

      Damtoft, S., Franzyk, H. & Jensen, S. R., D. S. ,. F. H. &. J. S. R., 1993, In: Phytochemistry. 34, p. 1291-1299

      Research output: Contribution to journalJournal articlepeer-review

    305. Iridoids and Verbascosides in Retzia

      Damtoft, S., Franzyk, H., Jensen, S. R. & Nielsen B.J., D. S. ,. F. H. ,. J. S. R. &. N. B. J., 1993, In: Phytochemistry. 34, p. 239-243

      Research output: Contribution to journalJournal articlepeer-review

    306. 1992
    307. Excelsioside, a Secoiridoid Glucoside from Fraxinus excelsior L.

      Damtoft, S., Franzyk, H. & Jensen, S. R., D. S. ,. F. H. &. J. S. R., 1992, In: Phytochemistry. 31, p. 4197-4201

      Research output: Contribution to journalJournal articlepeer-review

    ID: 1302063