Jesper M. Mathiesen
Associate Professor
Molecular and Cellular Pharmacology
Jagtvej 160
2100 København Ø
- 2003
- Published
Positive allosteric modulation of the human metabotropic glutamate receptor 4 (hmGluR4) by SIB-1893 and MPEP
Mathiesen, Jesper M., Svendsen, N., Bräuner, Hans, Thomsen, C. & Ramirez, M. T., Mar 2003, In: British Journal of Pharmacology. 138, 6, p. 1026-30Research output: Contribution to journal › Journal article › Research › peer-review
- 2005
- Published
Identification of indole derivatives exclusively interfering with a G protein-independent signaling pathway of the prostaglandin D2 receptor CRTH2
Mathiesen, Jesper M., Ulven, Trond, Martin, L., Gerlach, L., Heinemann, A. & Kostenis, E., 2005, In: Molecular Pharmacology. 68, 2, p. 393-402 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular pharmacology and therapeutic prospects of metabotropic glutamate receptor allosteric modulators
Ritzén, A., Mathiesen, Jesper M. & Thomsen, C., 1 Oct 2005, In: Basic and Clinical Pharmacology and Toxicology. 97, 4, p. 202-213 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2006
- Published
6-Acylamino-2-amino-4-methylquinolines as potent melanin-concentrating hormone 1 receptor antagonists
Ulven, Trond, Little, P. B., Receveur, J., Frimurer, Thomas Michael, Rist, Ø., Nørregaard, P. K., Mathiesen, Jesper M. & Högberg, T., 2006, In: Bioorganic & Medicinal Chemistry Letters. 16, 4, p. 1070-1075 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Novel selective orally active CRTH2 antagonists for allergic inflammation developed from in silico derived hits
Ulven, Trond, Receveur, J., Grimstrup, M., Rist, Ø., Frimurer, Thomas Michael, Gerlach, L., Mathiesen, Jesper M., Kostenis, E., Uller, L. & Högberg, T., 2006, In: Journal of Medicinal Chemistry. 49, 23, p. 6638-6641 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
On the mechanism of interaction of potent, surmountable and insurmountable antagonists with the prostaglandin D2 receptor CRTH2
Mathiesen, Jesper M., Christopoulos, A., Ulven, Trond, Royer, J. F., Campillo, M., Heinemann, A., Pardo, L. & Kostenis, E., 2006, In: Molecular Pharmacology. 69, 4, p. 1441-1453 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The metabotropic glutamate receptor 4 is internalized and desensitized upon protein kinase C activation
Mathiesen, Jesper M. & Ramirez, M. T., 1 Jun 2006, In: British Journal of Pharmacology. 148, 3, p. 279-290 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2007
- Published
Antagonism of the prostaglandin D2 receptor CRTH2 attenuates asthma pathology in mouse eosinophilic airway inflammation
Uller, L., Mathiesen, Jesper M., Alenmyr, L., Korsgren, M., Ulven, Trond, Högberg, T., Andersson, G., Persson, C. G. A. & Kostenis, E., 1 Feb 2007, In: Respiratory Research. 8, 16Research output: Contribution to journal › Journal article › Research › peer-review
- 2009
- Published
The C-terminal tail of CRTH2 is a key molecular determinant that constrains GalphaI- and downstream-signaling cascade activation
Schroeder, R., Merten, N., Mathiesen, Jesper M., Martini, L., Letunic, A. K., Krop, F., Blaukat, A., Fang, Y., Tran, E., Ulven, Trond, Drewke, C., Whistler, J., Pardo, L., Gomeza, J. & Kostenis, E., 2009, In: Journal of Biological Chemistry. 284, 2, p. 1324-1336 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2010
- Published
A new metabotropic glutamate receptor agonist with in vivo anti-allodynic activity
Stanley, N. J., Hutchinson, M. R., Kvist, T., Nielsen, Birgitte, Mathiesen, Jesper M., Bräuner, Hans, Avery, T. D., Tiekink, E. R. T., Pedersen, D. S., Irvine, R. J., Abell, A. D. & Taylor, D. K., 2010, In: Bioorganic & Medicinal Chemistry. 18, 16, p. 6089-6098Research output: Contribution to journal › Journal article › Research › peer-review
ID: 4873159
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155
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Gs protein peptidomimetics as allosteric modulators of the β2-adrenergic receptor
Research output: Contribution to journal › Journal article › Research › peer-review
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42
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Dissecting the roles of GRK2 and GRK3 in μ-opioid receptor internalization and β-arrestin2 recruitment using CRISPR/Cas9-edited HEK293 cells
Research output: Contribution to journal › Journal article › Research › peer-review
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25
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Delineation of the GPR15 receptor-mediated Gα protein signalling profile in recombinant mammalian cells
Research output: Contribution to journal › Journal article › Research › peer-review
Published