José Moreira

José Moreira

Professor


  1. 2024
  2. Accepted/In press

    Pepticinnamins N, O, and P, Nonribosomal Peptides from the Soil-Derived Streptomyces mirabilis P8-A2

    Mohamed, M. M. M., Abboud, M. M., Maleckis, M., De Oliveira Souza, Luciano, Moreira, José, Gotfredsen, C. H., Weber, T. & Ding, L., 2024, (Accepted/In press) In: Journal of Natural Products.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. 2023
  4. Published

    Proteomic Profiling of Colorectal Adenomas Identifies a Predictive Risk Signature for Development of Metachronous Advanced Colorectal Neoplasia

    Bech, J. M., Terkelsen, Thilde Bagger, Bartels, Annette Snejbjerg, Coscia, F., Doll, S., Zhao, S., Zhang, Z., Brünner, N., Lindebjerg, J., Madsen, G. I., Fang, X., Mann, Matthias & Moreira, José, 2023, In: Gastroenterology. 165, 1, p. 121-132.e5

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    The invariant chain CD74 protein is a cell surface binding partner of TIMP-1 in breast cancer cells

    Høeberg, M., Noer, Julie Boertmann, Vistesen, M. V., Bartels, Annette Snejbjerg, Bech, E. M., Nygård, S. B., Lademann, U., Stenvang, Jan, Liu, S., Fuglsang, Anja Thoe, Brünner, N. & Moreira, José, 2023, In: Molecular Oncology. 17, 8, p. 1595-1612

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Tissue Inhibitor of Metalloproteinases-1 Interacts with CD74 to Promote AKT Signaling, Monocyte Recruitment Responses, and Vascular Smooth Muscle Cell Proliferation

    Ebert, S., Zang, L., Ismail, N., Otabil, M., Fröhlich, A., Egea, V., Ács, S., Hoeberg, M., Berres, M. L., Weber, C., Moreira, José, Ries, C., Bernhagen, J. & El Bounkari, O., 2023, In: Cells. 12, 14, 24 p., 1899.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. 2022
  8. Published

    Itraconazole Reverts ABCB1-Mediated Docetaxel Resistance in Prostate Cancer

    Lima, T. S., De Oliveira Souza, Luciano, Iglesias Gato, Diego, Elversang, J., Jørgensen, Flemming Steen, Kallunki, Tuula Anneli, Røder, Andreas, Brasso, K. & Moreira, José, 2022, In: Frontiers in Pharmacology. 13, 13 p., 869461.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. 2021
  10. Published

    Functional proteomic profiling of triple-negative breast cancer

    Gromova, I., Espinoza, J. A., Grauslund, M., Santoni Rugiu, Eric, Talman, M. L. M., van Oostrum, J. & Moreira, José, 2021, In: Cells. 10, 10, 14 p., 2768.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    HLA Class II Histocompatibility Antigen gamma Chain (CD74) Expression Is Associated with Immune Cell Infiltration and Favorable Outcome in Breast Cancer

    Noer, Julie Boertmann, Talman, M. M. & Moreira, José, 2021, In: Cancers. 13, 24, 16 p., 6179.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Molecular Profiling of Docetaxel-Resistant Prostate Cancer Cells Identifies Multiple Mechanisms of Therapeutic Resistance

    Lima, T. S., Iglesias Gato, Diego, De Oliveira Souza, Luciano, Stenvang, Jan, Lima, D. S., Røder, Andreas, Brasso, K. & Moreira, José, 2021, In: Cancers. 13, 19 p.

    Research output: Contribution to journalJournal articleResearch

  13. Published

    The exercise-induced long noncoding RNA CYTOR promotes fast-twitch myogenesis in aging

    Wohlwend, M., Laurila, P., William, K., Romani, M., Lima, T., Pattawaran, P., Benegiamo, G., Salonen, M., Schneider, B. L., Lahti, J., Eriksson, J. G., Barrès, Romain, Wisloff, U., Moreira, José & Auwerx, J., 2021, In: Science Translational Medicine. 13, 623, 14 p., eabc7367.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. 2020
  15. Published

    A streamlined mass spectrometry-based proteomics workflow for large scale FFPE tissue analysis

    Coscia, F., Doll, S., Bech, J. M., Schweizer, L., Mund, Andreas, Lengyel, E., Lindebjerg, J., Madsen, G. I., Moreira, José & Mann, Matthias, 2020, In: Journal of Pathology. 251, p. 110-112

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. 2019
  17. Published

    Gel-Based Proteomics of Clinical Samples Identifies Potential Serological Biomarkers for Early Detection of Colorectal Cancer

    Thorsen, S. F., Gromova, I., Christensen, I. J., Fredriksson, S., Andersen, C. L., Nielsen, H. J., Stenvang, Jan & Moreira, José, Dec 2019, In: International Journal of Molecular Sciences (Online). 20, 19 p., 6082.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Allosteric regulation of AMP-activated protein kinase by adenylate nucleotides and small-molecule drugs

    Matos, A. L. D. S. A., Oakhill, J. S., Moreira, José, Loh, K., Galic, S. & Scott, J. W., 30 Apr 2019, In: Biochemical Society Transactions. 47, p. 733-741

    Research output: Contribution to journalReviewResearchpeer-review

  19. Published

    Metallopeptidase Inhibitor 1 (TIMP-1) promotes receptor tyrosine kinase c-Kit signaling in colorectal cancer

    Nordgaard, C., Doll, S., Matos, A. L. D. S. A., Høeberg, M., Kazi, J. U., Friis, S., Stenvang, Jan, Rönnstrand, L., Mann, Matthias & Moreira, José, 2019, In: Molecular Oncology. 13, 12, p. 2646-2662

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Proteogenomic characterization of patient-derived xenografts highlights the role of REST in neuroendocrine differentiation of castration-resistant prostate cancer

    Flores-Morales, A., Bergmann, T. B., Lavallee, C., Batth, T. S., Lin, D., Lerdrup, M., Friis, S., Bartels, A., Kristensen, G., Krzyzanowska, A., Xue, H., Fazli, L., Hansen, K., Røder, M. A., Brasso, K., Moreira, J. M., Bjartell, A., Wang, Y., Olsen, J. V., Collins, C. C. & 1 others, Iglesias Gato, Diego, 2019, In: Clinical Cancer Research. 25, 2, p. 1-15

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Release of transcriptional repression via ErbB2-induced, SUMO-directed phosphorylation of myeloid zinc finger-1 serine 27 activates lysosome redistribution and invasion

    Brix, D. M., Tvingsholm, S. A., Hansen, M. B., Clemmensen, K. B., Ohman, T., Siino, V., Lambrughi, M., Hansen, K., Puustinen, P., Gromova, I., James, P., Papaleo, E., Varjosalo, M., Moreira, José, Jäättelä, M. & Kallunki, Tuula Anneli, 2019, In: Oncogene. 38, p. 3170-3184

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. 2018
  23. Published

    Co-expression of TIMP-1 and its cell surface binding partner CD63 in glioblastomas

    Aaberg-Jessen, C., Sørensen, M. D., Matos, A. L. S. A., Moreira, José, Brünner, N., Møldrup Knudsen, A. & Kristensen, B. W., 9 Mar 2018, In: BMC Cancer. 18, 16 p., 270.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Let-7 microRNA controls invasion-promoting lysosomal changes via the oncogenic transcription factor myeloid zinc finger-1

    Tvingsholm, S. A., Hansen, M. B., Clemmensen, K. K. B., Brix, D. M., Rafn, B., Frankel, Lisa, Louhimo, R., Moreira, José, Hautaniemi, S., Gromova, I., Jäättelä, M. & Kallunki, Tuula Anneli, 2018, In: Oncogene. 7, 2, p. 1-15 15 p., 14.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Predictive value of combined analysis of pro-NPY and ERG in localized prostate cancer

    Kristensen, G., Røder, Andreas, Berg, K. D., Elversang, J., Iglesias Gato, Diego, Moreira, José, Toft, B. G. & Brasso, K., 2018, In: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica. 126, 10, p. 804-813

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    The net acid extruders NHE1, NBCn1 and MCT4 promote mammary tumor growth through distinct but overlapping mechanisms

    Andersen, Anne Poder, Samsøe-Petersen, Jacob, Ørnbo, E. K., Bødtkjer, E., Moreira, José, Kveiborg, Marie & Pedersen, Stine Helene Falsig, 2018, In: International Journal of Cancer. 142, 12, p. 2529-2542 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. 2017
  28. Published

    Molecular Oncology journal has moved to open access

    Celis, J. E. & Moreira, José, 1 Feb 2017, In: Molecular Oncology. 11, 2, 1 p.

    Research output: Contribution to journalEditorialResearchpeer-review

  29. Published

    Elucidation of Altered Pathways in Tumor-Initiating Cells of Triple-Negative Breast Cancer: A Useful Cell Model System for Drug Screening

    Christensen, A. G., Ehmsen, S., Terp, M. G., Batra, R., Alcaraz, N., Baumbach, J., Noer, Julie Boertmann, Moreira, José, Leth-Larsen, R., Larsen, M. R. & Ditzel, H. J., 2017, In: Stem Cells. 35, 8, p. 1898-1912

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Identification of BLCAP as a novel STAT3 interaction partner in bladder cancer

    Gromova, I., Svensson, S., Gromov, P. & Moreira, José, 2017, In: PloS one. 12, 11, 18 p., e0188827.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. 2016
  32. Published

    TIMP-1 is under regulation of the EGF signaling axis and promotes an aggressive phenotype in KRAS-mutated colorectal cancer cells: A potential novel approach to the treatment of metastatic colorectal cancer

    Tarpgaard, L. S., Ørum-Madsen, M. S., Christensen, I. J., Nordgaard, C., Noer, Julie Boertmann, Guren, T. K., Glimelius, B., Sorbye, H., Ikdahl, T., Kure, E. H., Tveit, K. M., phw435, P., Pfeiffer, P., Brünner, N. & Moreira, José, 8 Aug 2016, In: OncoTarget. 7, 37, p. 59441-59457 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    The stepwise evolution of the exome during acquisition of docetaxel resistance in breast cancer cells

    Hansen, S. N., Ehlers, Natasja Spring, Zhu, S., Thomsen, M. B. H., Nielsen, R. L., Liu, D., Wang, G., Hou, Y., Zhang, X., Xu, X., Bolund, L., Yang, H., Wang, J., Moreira, José, Ditzel, H. J., Brünner, N., Rasmussen, A. S., Stenvang, Jan & Gupta, R., 9 Jun 2016, In: B M C Genomics. 17, 15 p., 442.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Molecular characterization of irinotecan (SN-38) resistant human breast cancer cell lines

    Jandu, H., Aluzaité, K., Fogh, L., Thrane, S. W., Noer, J. B., Proszek, J., Nguyen Do, K., Hansen, S. N., Damsgaard-Hansen, B., Nielsen, S. L., Stougaard, M., Knudsen, B. R., Moreira, J., Hamerlik, P., Gajjar, M., Smid, M., Martens, J., Foekens, J., Pommier, Y., Brünner, N. & 2 others, Rasmussen, A. S. & Stenvang, Jan, 22 Jan 2016, In: B M C Cancer. 16, 13 p., 34.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. 2015
  36. Published

    Intact and cleaved plasma soluble urokinase receptor in patients with metastatic colorectal cancer treated with oxaliplatin with or without cetuximab

    Tarpgaard, L. S., Christensen, I. J., Høyer-Hansen, G., Lund, I. K., Guren, T. K., Glimelius, B., Sorbye, H., Tveit, K. M., Nielsen, H. J., Moreira, José, Pfeiffer, P. & Brünner, N., 15 Nov 2015, In: International Journal of Cancer. 137, 10, p. 2470-7 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Drug transporters in breast cancer: response to anthracyclines and taxanes

    Kümler, I., Stenvang, Jan, Moreira, José, Brünner, N. & Nielsen, Dorte Lisbet, Sep 2015, In: Expert Review of Anticancer Therapy. 15, 9, p. 1075-1092 18 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Topoisomerase-1 gene copy aberrations are frequent in patients with breast cancer

    Kümler, I., Balslev, E., Poulsen, T. S., Nielsen, Signe Lykke, Nygård, S. B., Rømer, M. U., Christensen, I. J., Høgdall, E., Moreira, José, Nielsen, Dorte Lisbet, Brünner, N. & Stenvang, Jan, 8 Apr 2015, In: International Journal of Cancer. 137, 8, p. 2000-2006 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Establishment and characterization of models of chemotherapy resistance in colorectal cancer: towards a predictive signature of chemoresistance

    Jensen, N. F., Stenvang, J., Beck, M. K., Hanáková, B., Belling, K. C., Do, K. N., Viuff, B. M., Nygård, S. B., Gupta, R., Rasmussen, M. H., Tarpgaard, L. S., Hansen, T. P., Budinská, E., Pfeiffer, P., Bosman, F., Tejpar, S., Roth, A., Delorenzi, M., Andersen, C. L., Rømer, M. U. K. & 2 others, Brünner, N. & Moreira, José, 24 Feb 2015, In: Molecular Oncology. 9, 6, p. 1169-1185 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Acquisition of docetaxel resistance in breast cancer cells reveals upregulation of ABCB1 expression as a key mediator of resistance accompanied by discrete upregulation of other specific genes and pathways

    Hansen, S. N., Westergaard, David, Thomsen, M. B. H., Vistesen, M. V., Do, K. N., Fogh, L., Belling, K. G., Wang, J., Yang, H., Gupta, R., Ditzel, H. J., Moreira, José, Brünner, N., Stenvang, Jan & Rasmussen, A. S., 2015, In: Tumor Biology. 36, 6, p. 4327-4338 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    High level PHGDH expression in breast is predominantly associated with keratin 5-positive cell lineage independently of malignancy

    Gromova, I., Gromov, P., Honma, N., Kumar, S., Rimm, D., Talman, M. M., Wielenga, V. T. & Moreira, José, 2015, In: Molecular Oncology. 9, 8, p. 1636-1654 19 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Identification and characterization of a new TIMP-1 binding protein

    Moreira, José, Høeberg, M., Lademann, U. A., Viuff, B. M., Jensen, L. V., Stenvang, Jan, Nygård, S. B., Ørum-Madsen, M. S., Vistesen, M. V., Fuglsang, Anja Thoe, Liu, S. & Brünner, N., 2015, In: Cancer Research. 75, 9 suppl., 1 p., Abstract P5-07-08.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  43. 2014
  44. Published

    Looking back, to go forward

    Moreira, José, 1 Jan 2014, In: Molecular Oncology. 8, 3, p. 445-446 2 p.

    Research output: Contribution to journalEditorialResearchpeer-review

  45. Published

    CIP2A oncoprotein controls cell growth and autophagy through mTORC1 activation: CIP2A oncoprotein controls cell growth and autophagy through mTORC1 activation

    Puustinen, P., Rytter, A., Mortensen, M., Kohonen, P., Moreira, José & Jäättelä, M., 2014, In: Journal of Cell Biology. 204, 5, p. 713-727 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Comparative analysis of evolutionarily conserved motifs of epidermal growth factor receptor 2 (HER2) predicts novel potential therapeutic epitopes

    Deng, X., Zheng, X., Yang, H., Moreira, José, Brünner, N. & Christensen, Henrik, 2014, In: PLOS ONE. 9, 9, 9 p., e106448.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    FABP7 and HMGCS2 are novel protein markers for apocrine differentiation categorizing apocrine carcinoma of the breast

    Gromov, P., Espinoza, J. A., Talman, M., Honma, N., Kroman, N., Wielenga, V. T., Moreira, José & Gromova, I., 2014, In: P L o S One. 9, 11, 14 p., e112024.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Interactions of ion transporters and channels with cancer cell metabolism and the tumour microenvironment

    Andersen, Anne Poder, Moreira, José & Pedersen, Stine Helene Falsig, 2014, In: Philosophical Transactions of the Royal Society B: Biological Sciences. 369, 1638, 11 p., 20130098.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Proteomic analysis of tissue samples in translational breast cancer research

    Gromov, P., Moreira, José & Gromova, I., 2014, In: Expert Review of Proteomics. 11, 3, p. 285-302 18 p.

    Research output: Contribution to journalReviewResearchpeer-review

  50. Published

    Purification and characterization of bioactive his6-tagged recombinant human tissue inhibitor of metalloproteinases-1 (TIMP-1) protein expressed at high yields in mammalian cells

    Jensen, L. V., Lademann, U. A., Andersen, E. V., Højrup, P., Thaysen-Andersen, M., Krogh, B. O., Viuff, B. M., Brünner, N., Stenvang, Jan & Moreira, José, 2014, In: Protein Expression and Purification. 101, p. 157-164 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. 2013
  52. Published

    TIMP-1 increases expression and phosphorylation of proteins associated with drug resistance in breast cancer cells

    Hekmat, O., Munk, S., Fogh, L., Yadav, R., Francavilla, C., Horn, H., Würtz, S. Ø., Schrohl, A-S., Damsgaard, B., Romer, M. U., Belling, K., Jensen, N. F., Gromova, I., Bekker-Jensen, D. B., Moreira, J., Jensen, L. J., Gupta, R., Lademann, U. A., Brünner, N., Olsen, J. V. & 1 others, Stenvang, Jan, 5 Aug 2013, In: Journal of Proteome Research. 12, 9, p. 4136-4151 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Biomarker-guided repurposing of chemotherapeutic drugs for cancer therapy: a novel strategy in drug development

    Stenvang, Jan, Kümler, I., Nygård, S. B., Smith, D. H., Nielsen, D., Brünner, N. & Moreira, José, 2013, In: Frontiers in Oncology. 3, 9 p., 313.

    Research output: Contribution to journalReviewResearchpeer-review

  54. Published

    Contribution of Na+,HCO3--cotransport to cellular pH control in human breast cancer: a role for the breast cancer susceptibility locus NBCn1 (SLC4A7)

    Bødtkjer, E., Moreira, José, Mele, M., Vahl, P., Wielenga, V. T., Christiansen, P. M., Jensen, V. E. D., Pedersen, Stine Helene Falsig & Aalkjær, C., 2013, In: International Journal of Cancer. 132, 6, p. 1288-1299 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    Proteomic profiling of triple-negative breast carcinomas in combination with a three-tier orthogonal technology approach identifies Mage-A4 as potential therapeutic target in estrogen receptor negative breast cancer

    Cabezón, T., Gromova, I., Gromov, P., Serizawa, R. R., Wielenga, V. T., Kroman, Niels Thorndahl, Celis, J. E. & Moreira, José, 2013, In: Molecular & Cellular Proteomics. 12, 2, p. 381-394 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Published

    Proximity probing assays for simultaneous visualization of protein complexes in situ

    Moreira, José, Thorsen, S. B., Brünner, N. & Stenvang, Jan, 2013, In: Expert Review of Proteomics. 10, 3, p. 219-221 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. Published

    Tumor interstitial fluid: a treasure trove of cancer biomarkers

    Gromov, P., Gromova, I., Olsen, C. J., Timmermans-Wielenga, V., Talman, M., Serizawa, R. R. & Moreira, José, 2013, In: B B A - Proteins and Proteomics. 1834, 11, p. 2259-2270 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. 2012
  59. ErbB2-driven breast cancer cell invasion depends on a complex signaling network activating myeloid zinc finger-1-dependent cathepsin B expression

    Rafn, B., Nielsen, C. F., Andersen, S. H., Szyniarowski, P., Corcelle-Termeau, E., Valo, E., Fehrenbacher, N., Olsen, C. J., Daugaard, M., Egebjerg, C., Bøttzauw, T., Kohonen, P., Nylandsted, J., Hautaniemi, S., Moreira, José, Jaattela, M. & Kallunki, T., 2012, In: Molecular Cell. 45, 6, p. 764-776 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  60. Published

    Immunoexpression analysis and prognostic value of BLCAP in breast cancer

    Gromova, I., Gromov, P., Kroman, N., Wielenga, V. T., Simon, R., Sauter, G. & Moreira, José, 2012, In: P L o S One. 7, 9, 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  61. 2010
  62. Published

    Challenges and Opportunities in Oncoproteomics

    Celis, J. E. & Moreira, José, 1 Jan 2010, In: Molecular Oncology. 4, 6, p. 459-460 2 p.

    Research output: Contribution to journalEditorialResearchpeer-review

  63. Published

    Human mammary fibroblasts stimulate invasion of breast cancer cells in a three-dimensional culture and increase stroma development in mouse xenografts.

    Olsen, C. J., Moreira, José, Lukanidin, E. M. & Ambartsumian, N. S., 1 Jan 2010, In: BMC Cancer. 10, 1 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  64. Bladder cancer-associated protein, a potential prognostic biomarker in human bladder cancer

    Moreira, José, Ohlsson, G., Gromov, P., Simon, R., Sauter, G., Celis, J. E. & Gromova, I., 2010, In: Molecular & Cellular Proteomics. 9, 1, p. 161-77 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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