Kasper Harpsøe

Kasper Harpsøe

Research consultant


  1. 2012
  2. Published

    Covalent attachment of antagonists to the a7 nicotinic acetylcholine receptor: synthesis and reactivity of substituted maleimides

    Ambrus, J. I., Halliday, J. I., Kanizaj, N., Absalom, N., Harpsøe, Kasper, Balle, T., Chebib, M. & McLeod, M. D., 7 Jul 2012, In: Chemical Communications. 48, 53, p. 6699-6701 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Intersubunit bridge formation governs agonist efficacy at nicotinic acetylcholine alpha4beta2 receptors: Unique role of halogen bonding revealed

    Rohde, L. A. H., Ahring, P. K., Jensen, M. L., Nielsen, E. Ø., Peters, D., Helgstrand, C., Krintel, C., Harpsøe, Kasper, Gajhede, Michael, Kastrup, Jette Sandholm Jensen & Balle, T., 3 Feb 2012, In: The Journal of Biological Chemistry. 287, 6, p. 4248-4259

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Nyt bindingssted i nikotine acetylcholinreceptorer: håb om ny behandling af eksempelvis ADHD og Alzheimers sygdom

    Harpsøe, Kasper & Balle, T., Feb 2012, In: BestPractice Psykiatri/Neurologi. 5, 16, p. 7-10 4 p.

    Research output: Contribution to journalJournal articleCommunication

  5. Published

    A robust force field based method for calculating conformational energies of charged drug-like molecules

    Pøhlsgaard, J., Harpsøe, Kasper, Jørgensen, Flemming Steen & Olsen, L., 2012, In: Journal of Chemical Information and Modeling. 52, 2, p. 409-419

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Discovery of a novel allosteric modulator of 5-HT3 receptor: Inhibition and potentiation of Cys-loop receptor signaling through a conserved transmembrane intersubunit site

    Trattnig, S. M., Harpsøe, Kasper, Thygesen, S. B., Rahr, L. M., Ahring, P. K., Balle, T. & Jensen, Anders A., 2012, In: Journal of Biological Chemistry. 287, 30, p. 25241-25254

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Pharmacological characterization and modeling of the binding sites of novel 1,3-bis(pyridinylethynyl)benzenes as metabotropic glutamate receptor 5-selective negative allosteric modulators

    Mølck, C., Harpsøe, Kasper, Gloriam, David E., Clausen, Rasmus Prætorius, Madsen, Ulf, Pedersen, L., Jimenez, H. N., Nielsen, S. M., Mathiesen, Jesper M. & Bräuner, Hans, 2012, In: Molecular Pharmacology. 82, 5, p. 929-37 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Structure-activity relationships for negative allosteric mGluR5 modulators

    Kaae, B. H., Harpsøe, Kasper, Kvist, T., Mathiesen, Jesper M., Mølck, C., Gloriam, David E., Jimenez, H. N., Uberti, M. A., Nielsen, S. M., Nielsen, Birgitte, Bräuner, Hans, Sauerberg, P., Clausen, Rasmus Prætorius & Madsen, Ulf, 2012, In: ChemMedChem. 7, 3, p. 440-451

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 1428429