Osman Asghar Mirza

Osman Asghar Mirza

Associate Professor

ORCID: 0000-0001-9435-0690

Publication year:
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1 - 84 out of 84Page size: 100
  1. 2024
  2. Published

    Structure-guided optimization of 3-hydroxybenzoisoxazole derivatives as inhibitors of Aldo-keto reductase 1C3 (AKR1C3) to target prostate cancer

    Pippione, A. C., Kovachka, S., Vigato, C., Bertarini, L., Mannella, I., Sainas, S., Rolando, B., Denasio, E., Piercy-Mycock, H., Romalho, L., Salladini, E., Adinolfi, S., Zonari, D., Peraldo-Neia, C., Chiorino, G., Passoni, A., Mirza, O. A., Frydenvang, K., Pors, K., Lolli, M. L. & 3 others, Spyrakis, F., Oliaro-Bosso, S. & Boschi, D., 2024, In: European Journal of Medicinal Chemistry. 268, 20 p., 116193.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. 2023
  4. Published

    Functional Characterization of the Putative POT from Clostridium perfringens

    Gharabli, H., Rafiq, M., Iqbal, A., Yan, R., Aduri, N. G., Sharma, N., Prabhala, B. K. & Mirza, Osman Asghar, 2023, In: Biology. 12, 5, 11 p., 651.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Accepted/In press

    Identification of additional mechanistically important residues in the multidrug transporter styMdtM of Salmonella Typhi

    Shaheen, A., Tariq, A., Ismat, F., Naveed, H., De Zorzi, R., Iqbal, M., Storici, P., Mirza, Osman Asghar, Walz, T. & Rahman, M., 2023, (Accepted/In press) In: Journal of Biomolecular Structure and Dynamics.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Identification of key amino acid residues in AtUMAMIT29 for transport of glucosinolates

    Meyer, L., Crocoll, C., Halkier, Barbara Ann, Mirza, Osman Asghar & Xu, Deyang, 2023, In: Frontiers in Plant Science. 14, 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Physiological response in E. coli to YdgR overexpression depends on whether the protein has an intact function

    Sajid, Salvia, Salas, L. H., Rafiq, M., Lund, T., Jørgensen, M. G., Honoré, B., Christensen, L. P., Hansen, Paul Robert, Franzyk, Henrik, Mirza, Osman Asghar & Prabhala, B. K., 2023, In: Biochemical and Biophysical Research Communications. 661, p. 42-49

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Substrate space analysis of the bacterial proton-coupled oligopeptide transporter YdgR by cheminformatics

    Sajid, Salvia, Nielsen, M. M. K., Khalil, R., Hansen, Paul Robert, Franzyk, Henrik, Jørgensen, M. G., Christensen, L. P., Mirza, Osman Asghar & Prabhala, B. K., 2023, In: FEMS Microbiology Letters. 370, 9 p., fnad052.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Accepted/In press

    The Y-ome Conundrum: Insights into Uncharacterized Genes and Approaches for Functional Annotation

    Sajid, Salvia, Mashkoor, M., Jørgensen, M. G., Christensen, L. P., Hansen, Paul Robert, Franzyk, Henrik, Mirza, Osman Asghar & Prabhala, B. K., 2023, (Accepted/In press) In: Molecular and Cellular Biochemistry. 12 p.

    Research output: Contribution to journal › Review › Research › peer-review

  10. 2022
  11. Published

    Expression, purification and characterization of human proton-coupled oligopeptide transporter 1 hPEPT1

    Rafiq, M., Ernst, H. A., Aduri, N. G., Prabhala, B. K., Tufail, S., Rahman, M., Bloch, Magnus Borup, Mirza, N., Taylor, Nicholas M I, Boesen, T., Gajhede, Michael & Mirza, Osman Asghar, 2022, In: Protein Expression and Purification. 190, 7 p., 105990.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Highly soluble and stable ‘insertion domain’ of the capsid penton base protein provides complete protection against infections caused by fowl adenoviruses

    Tufail, S., Shah, M. A., Asif, T. A., Ullah, R., Shehzad, A., Ismat, F., Shah, M. S., Habib, M., Calisto, B. M., Mirza, Osman Asghar, Iqbal, M. & Rahman, M., 2022, In: Microbial Pathogenesis. 173, Part A, 6 p., 105835.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Structural Insights into the Substrate Transport Mechanisms in GTR Transporters through Ensemble Docking

    Peña‐Varas, C., Kanstrup, Christa, Vergara‐jaque, A., González‐avendaño, M., Crocoll, C., Mirza, Osman Asghar, Dreyer, I., Nour-Eldin, Hussam Hassan & Ramírez, D., 2022, In: International Journal of Molecular Sciences. 23, 3, 20 p., 1595.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Structure of the proteolytic enzyme PAPP-A with the endogenous inhibitor stanniocalcin-2 reveals its inhibitory mechanism

    Kobberø, S. D., Gajhede, Michael, Mirza, Osman Asghar, Kløverpris, S., Kjær, T. R., Mikkelsen, J. H., Boesen, T. & Oxvig, C., 2022, In: Nature Communications. 13, 1, 16 p., 6084.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. 2021
  16. Published

    Binding of a negative allosteric modulator and competitive antagonist can occur simultaneously at the ionotropic glutamate receptor GluA2

    Krintel, C., Dorosz, J., Larsen, A. H., Thorsen, T. S., Venskutonytė, R., Mirza, Osman Asghar, Gajhede, Michael, Boesen, T. & Kastrup, Jette Sandholm Jensen, 2021, In: The FEBS Journal. 288, p. 995-1007 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Characterization of the multidrug efflux transporter styMdtMfrom Salmonella enterica serovar Typhi

    Shaheen, A., Ismat, F., Iqbal, M., Haque, A., Ul-Haq, Z., Mirza, Osman Asghar, De Zorzi, R., Walz, T. & Rahman, M., 2021, In: Proteins: Structure, Function, and Bioinformatics. 89, 9, p. 1193-1204

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Identification of potent epitopes on hexon capsid protein and their evaluation as vaccine candidates against infections caused by members of Adenoviridae family

    Tufail, S., Shah, M. A., Zafar, M., Asif, T. A., Shehzad, A., Shah, M. S., Habib, M., Saleemi, M. K., Muddassar, M., Mirza, Osman Asghar, Iqbal, M. & Rahman, M., 2021, In: Vaccine. 39, 27, p. 3560-3564 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Mutational Diversity in the Quinolone Resistance-Determining Regions of Type-II Topoisomerases of Salmonella Serovars

    Shaheen, A., Tariq, A., Iqbal, M., Mirza, Osman Asghar, Haque, A., Walz, T. & Rahman, M., 2021, In: Antibiotics. 10, 12, 26 p., 1455.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    PTR2/POT/NPF transporters: what makes them tick?

    Prabhala, B. K., Rahman, M., Nour-Eldin, Hussam Hassan, Jørgensen, Flemming Steen & Mirza, Osman Asghar, 2021, In: Advances in Protein Chemistry and Structural Biology. 123, p. 219-240 22 p.

    Research output: Contribution to journal › Review › Research › peer-review

  21. Published

    Sulpiride Serves, a Substrate for the Gut Microbiome

    Mukhtar, I., Anwar, H., Mirza, Osman Asghar, Ali, Q., Ijaz, M. U., Hume, M., Prabhala, B. K., Iftikhar, A., Hussain, G., Sohail, M. U. & Khan, K. U. R., 2021, In: Dose-Response. 19, 1, 7 p., 1559325820987943.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. 2020
  23. Published

    Expression of ESAT-6 antigen from Mycobacterium tuberculosis in broccoli: An edible plant

    Saba, K., Sameeullah, M., Asghar, A., Gottschamel, J., Latif, S., Lössl, A. G., Mirza, B., Mirza, Osman Asghar & Waheed, M. T., 2020, In: Biotechnology and Applied Biochemistry. 67, 1, p. 148-157 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Transcriptional regulation of drug resistance mechanisms in Salmonella: where we stand and what we need to know

    Shaheen, A., Tariq, A., Shehzad, A., Iqbal, M., Mirza, Osman Asghar, Maslov, D. A. & Rahman, M., 2020, In: World journal of microbiology & biotechnology. 36, 6, 8 p., 85.

    Research output: Contribution to journal › Review › Research › peer-review

  25. 2019
  26. Published

    An Optimized Screen Reduces the Number of GA Transporters and Provides Insights Into Nitrate Transporter 1/Peptide Transporter Family Substrate Determinants

    Wulff, N., Ernst, H. A., Jørgensen, M. E., Lambertz, S., Maierhofer, T., Belew, Zeinu Mussa, Crocoll, C., Motawie, Mohammed Saddik, Geiger, D., Jørgensen, Flemming Steen, Mirza, Osman Asghar & Nour-Eldin, Hussam Hassan, 3 Oct 2019, In: Frontiers in Plant Science. 10, 18 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Reserpine Is the New Addition into the Repertoire of AcrB Efflux Pump Inhibitors

    Shaheen, A., Afridi, W. A., Mahboob, S., Sana, M., Zeeshan, N., Ismat, F., Mirza, Osman Asghar, Iqbal, M. & Rahman, M., 10 Aug 2019, In: Molecular Biology. 53, 4, p. 674-684 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Changing substrate specificity and iteration of amino acid chain elongation in glucosinolate biosynthesis through targeted mutagenesis of Arabidopsis methylthioalkylmalate synthase1

    Petersen, A., Gram Hansen, L., Mirza, N., Crocoll, C., Mirza, Osman Asghar & Halkier, Barbara Ann, Jul 2019, In: Bioscience Reports. 39, p. 1-15 BSR20190446.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Detection of Paracetamol as substrate of the gut microbiome

    Mukhtar, I., Anwar, H., Hussain, G., Rasul, A., Naqvi, S. A. R., Faisal, M. N., Mustafa, I., Malik, S., Shaukat, A., Mirza, Osman Asghar & Sohail, M. U., Mar 2019, In: Pakistan Journal of Pharmaceutical Sciences. 32, 2 (Supplementary), p. 751-757 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Molecular Dynamics Simulations Reveal the Proton:Peptide Coupling Mechanism in the Bacterial Proton-Coupled Oligopeptide Transporter YbgH

    Aduri, N. G., Montefiori, M., Khalil, R., Gajhede, Michael, Jørgensen, Flemming Steen & Mirza, Osman Asghar, 31 Jan 2019, In: ACS Omega. 4, 1, p. 2040-2046 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    An Optimized Screen Reduces the Number of GA Transporters and provides Insights into NPF Substrate Determinants

    Wulff, N., Ernst, H. A., Jørgensen, M. E., Lambertz, S., Maierhofer, T., Belew, Zeinu Mussa, Crocoll, C., Motawia, M. S., Geiger, D., Jørgensen, Flemming Steen, Mirza, Osman Asghar & Nour-Eldin, Hussam Hassan, 2019, bioRxiv.

    Research output: Working paper › Preprint › Research

  32. Published

    In silico Epitope Prediction and Immunogenic Analysis for Penton base Epitope-focused Vaccine against Hydropericardium syndrome in chicken

    Aziz, F., Tufail, S., Shah, M. A., Salahuddin Shah, M., Habib, M., Mirza, Osman Asghar, Iqbal, M. & Rahman, M., 2019, In: Virus Research. 197750.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Molecular architecture of the Jumonji C family histone demethylase KDM5B

    Dorosz, J., Kristensen, L. H., Aduri, N. G., Mirza, Osman Asghar, Lousen, R., Bucciarelli, S., Mehta, V., Sellés Baiget, Selene, Solbak, Sara Marie Øie, Bach, Anders, Mesa, Pablo, Hernandez, P. A., Montoya, Guillermo, Nguyen, T. T. T. N., Rand, Kasper Dyrberg, Boesen, T. & Gajhede, Michael, 2019, In: Scientific Reports. 9, 13 p., 4019.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Restraining the multidrug efflux transporter STY4874 of Salmonella Typhi by reserpine and plant extracts

    Tariq, A., Sana, M., Shaheen, A., Ismat, F., Mahboob, S., Rauf, W., Mirza, Osman Asghar, Iqbal, M. & Rahman, M., 2019, In: Letters in Applied Microbiology. 69, 3, p. 161-167

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Structural analysis of Cytochrome P450 BM3 mutant M11 in complex with dithiothreitol

    Frydenvang, Karla Andrea, Verkade-Vreeker, M. C. A., Dohmen, F., Commandeur, J. N. M., Rafiq, M., Mirza, Osman Asghar, Jørgensen, Flemming Steen & Geerke, D. P., 2019, In: PLoS ONE. 14, 5, 15 p., e0217292.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. 2018
  37. Published

    Human proton coupled folic acid transporter is a monodisperse oligomer in the lauryl maltose neopentyl glycol solubilized state

    Aduri, N. G., Ernst, H. A., Prabhala, B. K., Bhatt, S., Boesen, T., Gajhede, Michael & Mirza, Osman Asghar, 2018, In: Biochemical and Biophysical Research Communications. 495, 2, p. 1738-1743 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    The prototypical proton-coupled oligopeptide transporter YdgR from Escherichia coli facilitates chloramphenicol uptake into bacterial cells

    Prabhala, B. K., Aduri, N. G., Sharma, N., Shaheen, A., Sharma, A., Iqbal, M., Hansen, Paul Robert, Brasen, C., Gajhede, Michael, Rahman, M. & Mirza, Osman Asghar, 2018, In: The Journal of Biological Chemistry. 293, p. 1007-1017

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. 2017
  40. Published

    Functional characterization and crystal structure of thermostable amylase from Thermotoga petrophila, reveals high thermostability and an unusual form of dimerization

    Hameed, U., Price, I., Ikram-Ul-Haq, Ke, A., Wilson, D. B. & Mirza, Osman Asghar, Oct 2017, In: B B A - Proteins and Proteomics. 1865, 10, p. 1237-1245 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Structural Biology Meets Drug Resistance: An Overview on Multidrug Resistance Transporters

    Shaheen, A., Iqbal, M., Mirza, Osman Asghar & Rahman, M., 1 Jun 2017, In: Journal of the Indian Institute of Science. 97, 2, p. 165-175 11 p.

    Research output: Contribution to journal › Review › Research › peer-review

  42. Published

    Anandamide and 2-AG Are Endogenously Present within the Laterodorsal Tegmental Nucleus: Functional Implications for a role of eCBs in arousal

    Soni, N., Prabhala, B. K., Mehta, V., Mirza, Osman Asghar & Kohlmeier, Kristi Anne, Jun 2017, In: Brain Research. 1665, p. 74-79 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Several hPepT1-transported drugs are substrates of the Escherichia coli proton-coupled oligopeptide transporter YdgR

    Prabhala, B. K., Aduri, N. G., Iqbal, M., Rahman, M., Gajhede, Michael, Hansen, Paul Robert & Mirza, Osman Asghar, 16 Feb 2017, In: Research in Microbiology. 168, 5, p. 443-449

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Expression, purification and characterization of the human MTA2-RBBP7 complex

    Brasen, C., Dorosz, J., Wiuf, A., Boesen, T., Mirza, Osman Asghar & Gajhede, Michael, 4 Feb 2017, In: Biochimica et biophysica acta. 1865, 5, p. 531-538 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Origin and evolution of transporter substrate specificity within the NPF family: [with Correction]

    Jørgensen, M. E., Xu, Deyang, Crocoll, C., Ernst, H. A., Ramírez, D., Motawie, Mohammed Saddik, Olsen, C. E., Mirza, Osman Asghar, Nour-Eldin, Hussam Hassan & Halkier, Barbara Ann, 2017, In: eLife. 6, 30 p., e19466.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. 2016
  47. Published

    Activity of the Human Rhinovirus 3C Protease Studied in Various Buffers, Additives and Detergents Solutions for Recombinant Protein Production

    Ullah, R., Shah, M. A., Tufail, S., Ismat, F., Imran, M., Iqbal, M., Mirza, Osman Asghar & Rhaman, M., 2016, In: PloS one. 11, 4, 13 p., e0153436.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Peptide Selectivity of the Proton-Coupled Oligopeptide Transporter from Neisseria meningitidis

    Sharma, N., Aduri, N. G., Iqbal, A., Prabhala, B. K. & Mirza, Osman Asghar, 2016, In: Journal of Molecular Microbiology and Biotechnology. 26, 5, p. 312-9 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. 2015
  50. Published

    Monitoring mammary tumor progression and effect of tamoxifen treatment in MMTV-PymT using MRI and magnetic resonance spectroscopy with hyperpolarized [1-(13) C]pyruvate

    Asghar Butt, S., Søgaard, L. V., Ardenkjaer-Larsen, J. H., Lauritzen, M. H., Engelholm, L. H., Paulson, Olaf B., Mirza, Osman Asghar, Holck, S., Magnusson, P. & Akeson, P., 16 Jan 2015, In: Magnetic Resonance in Medicine. 73, p. 51-58 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    A functional EXXEK motif is essential for proton coupling and active glucosinolate transport by NPF2.11

    Jørgensen, M. E., Olsen, C. E., Geiger, D., Mirza, Osman Asghar, Halkier, Barbara Ann & Nour-Eldin, Hussam Hassan, 2015, In: Plant and Cell Physiology. 56, 12, p. 2340-2350 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    Characterization of putative multidrug resistance transporters of the major facilitator-superfamily expressed in Salmonella Typhi

    Shaheen, A., Ismat, F., Iqbal, M., Haque, A., De Zorzi, R., Mirza, Osman Asghar, Walz, T. & Rahman, M., 2015, In: Journal of Infection and Chemotherapy. 21, 5, p. 357–362 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  53. Published

    Characterization of synthetic peptides by mass spectrometry

    Prabhala, B. K., Mirza, Osman Asghar, Højrup, P. & Hansen, Paul Robert, 2015, Methods in Molecular Biology: Peptide Antibiodies. Springer, p. 77-82

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  54. Published

    Investigation of the substrate specificity of the proton coupled peptide transporter PepTSo from Shewanella oneidensis

    Prabhala, B. K., Aduri, N. G., Hald, H. & Mirza, Osman Asghar, 2015, In: International Journal of Peptide Research and Therapeutics. 15, 21, p. 1-6 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  55. Published

    Salt-bridge Swapping in the EXXERFXYY Motif of Proton Coupled Oligopeptide Transporters

    Aduri, N. G., Prabhala, B. K., Ernst, H. A., Jørgensen, Flemming Steen, Olsen, L. & Mirza, Osman Asghar, 2015, In: The Journal of Biological Chemistry. 290, 50, p. 29931-29940 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  56. 2014
  57. Published

    Critical role of a conserved transmembrane lysine in substrate recognition by the proton-coupled oligopeptide transporter YjdL

    Jensen, J. M., Aduri, N. G., Prabhala, B. K., Jahnsen, R., Franzyk, Henrik & Mirza, Osman Asghar, 24 Sep 2014, In: International Journal of Biochemistry & Cell Biology. 55, p. 311-17 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  58. Published

    New insights into the substrate specificities of proton-coupled oligopeptide transporters from E. coli by a pH sensitive assay

    Prabhala, B. K., Aduri, N. G., Jensen, J. M., Ernst, H. A., Iram, N., Rahman, M. & Mirza, Osman Asghar, 16 Jan 2014, In: FEBS Letters. 588, 4, p. 560-565

    Research output: Contribution to journal › Journal article › Research › peer-review

  59. 2013
  60. Published

    The structure of amylosucrase from Deinococcus radiodurans has an unusual open active-site topology

    Skov, L. K., Pizzut-Serin, S., Remaud-Simeon, M., Ernst, H. A., Gajhede, Michael & Mirza, Osman Asghar, Sep 2013, In: Acta Crystallographica. Section F: Structural Biology and Crystallization Communications Online. 69, Pt 9, p. 973-8 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  61. 2012
  62. Published

    Biophysical characterization of the proton-coupled oligopeptide transporter YjdL

    Jensen, J. M., Simonsen, F. C., Mastali, A., Hald, H., Lillebro, I., Diness, Frederik, Olsen, L. & Mirza, Osman Asghar, Nov 2012, In: Peptides. 38, 1, p. 89-93 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  63. Published

    Functional investigation of conserved membrane-embedded glutamate residues in the proton-coupled peptide transporter YjdL

    Jensen, J. M., Ernst, H. A., Wang, X., Hald, H., Ditta, A. C., Ismat, F., Rahman, M. & Mirza, Osman Asghar, Mar 2012, In: Protein and Peptide Letters. 19, 3, p. 282-287

    Research output: Contribution to journal › Journal article › Research › peer-review

  64. Published

    Probing the putative active site of YjdL: an unusual proton-coupled oligopeptide transporter from E. coli

    Jensen, J. M., Ismat, F., Szakonyi, G., Rahman, M. & Mirza, Osman Asghar, 2012, In: P L o S One. 7, 10, p. e47780

    Research output: Contribution to journal › Journal article › Research › peer-review

  65. 2010
  66. Published

    Strukturer af membranproteiner: nøglen til rationelt lægemiddeldesign

    Hald, H. & Mirza, Osman Asghar, Dec 2010, In: Lægemiddelforskning. 2010, p. 13-15

    Research output: Contribution to journal › Journal article › Communication

  67. Published

    Over-expression, purification and characterization of an Asc-1 homologue from Gloeobacter violaceus

    Wang, X., Hald, H., Ernst, H. A., Egebjerg, J., Christensen, K. V., Gajhede, Michael, Kastrup, Jette Sandholm Jensen & Mirza, Osman Asghar, 2010, In: Protein Expression and Purification. 71, 2, p. 179-183

    Research output: Contribution to journal › Journal article › Research › peer-review

  68. 2009
  69. Published

    Ligand binding analyses of the putative peptide transporter YjdL from E. coli display a significant selectivity towards dipeptides

    Ernst, H. A., Pham, A., Hald, H., Kastrup, Jette Sandholm Jensen, Rahman, M. & Mirza, Osman Asghar, 2009, In: Biochemical and Biophysical Research Communications. 389, 1, p. 112-116

    Research output: Contribution to journal › Journal article › Research › peer-review

  70. Published

    The apo structure of sucrose hydrolase from Xanthomonas campestris pv. campestris shows an open active-site groove

    Champion, E., Remaud-Simeon, M., Skov, L. K., Kastrup, Jette Sandholm Jensen, Gajhede, Michael & Mirza, Osman Asghar, 2009, In: Acta Crystallographica. Section D: Biological Crystallography. 65, 12, p. 1309-1314

    Research output: Contribution to journal › Journal article › Research › peer-review

  71. 2008
  72. Published

    Structure and molecular mechanism of a nucleobase-cation-symport-1 family transporter

    Weyand, S., Shimamura, T., Yajima, S., Suzuki, S., Mirza, Osman Asghar, Krusong, K., Carpenter, E. P., Rutherford, N. G., Hadden, J. M., O'Reilly, J., Ma, P., Saidijam, M., Patching, S. G., Hope, R. J., Norbertczak, H. T., Roach, P. C. J., Iwata, S., Henderson, P. J. F. & Cameron, A. D., 2008, In: Science. 322, 5902, p. 709-713

    Research output: Contribution to journal › Journal article › Research › peer-review

  73. Published

    Structures of the ligand-binding core of iGluR2 in complex with the agonists (R)- and (S)-2-amino-3-(4-hydroxy-1,2,5-thiadiazol-3-yl)propionic acid explain their unusual equipotency

    Beich-Frandsen, M., Pickering, Darryl S, Mirza, Osman Asghar, Johansen, Tommy Nørskov, Greenwood, J., Vestergaard, Bente, Schousboe, Arne, Gajhede, Michael, Liljefors, T. & Kastrup, Jette Sandholm Jensen, 2008, In: Journal of Medicinal Chemistry. 51, 5, p. 1459-63

    Research output: Contribution to journal › Journal article › Research › peer-review

  74. Published

    The structure of the complex between a branched pentasaccharide and Thermobacillus xylanilyticus GH-51 arabinofuranosidase reveals xylan-binding determinants and induced fit

    Paës, G., Skov, L. K., O'Donohue, M. J., Rémond, C., Kastrup, Jette Sandholm Jensen, Gajhede, Michael & Mirza, Osman Asghar, 2008, In: Biochemistry. 47, 28, p. 7441-7451

    Research output: Contribution to journal › Journal article › Research › peer-review

  75. 2007
  76. Published

    Activation of ERK, JNK, Akt, and G-protein coupled signaling by hybrid angiotensin II AT1/bradykinin B2 receptors expressed in HEK-293 cells

    Yu, J., Lubinsky, D., Tsomaia, N., Huang, Z., Taylor, L., Mierke, D., Navarro, J., Mirza, Osman Asghar & Polgar, P., 2007, In: Journal of Cellular Biochemistry. 101, 1, p. 192-204

    Research output: Contribution to journal › Journal article › Research › peer-review

  77. Published

    Structural determination of wild-type lactose permease

    Guan, L., Mirza, Osman Asghar, Verner, G., Iwata, S. & Kaback, H. R., 2007, In: Proceedings of the National Academy of Science of the United States of America. 104, 39, p. 15294-15298

    Research output: Contribution to journal › Journal article › Research › peer-review

  78. Published

    Structures of OppA and PstS from Yersinia pestis indicate variability of interactions with transmembrane domains

    Tanabe, M., Mirza, Osman Asghar, Bertrand, T., Atkins, H. S., Titball, R. W., Iwata, S., Brown, K. A. & Byrne, B., 2007, In: Acta Crystallographica. Section D: Biological Crystallography. 63, 11, p. 1185-1193

    Research output: Contribution to journal › Journal article › Research › peer-review

  79. 2006

  80. The ABC transporter protein OppA provides protection against experimental Yersinia pestis infection

    Tanabe, M., Atkins, H. S., Harland, D. N., Elvin, S. J., Stagg, A. J., Mirza, Osman Asghar, Titball, R. W., Byrne, B. & Brown, K. A., Jun 2006, In: Infection and Immunity. 74, 6, p. 3687-91 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  81. Fumarate reductase and succinate oxidase activity of Escherichia coli complex II homologs are perturbed differently by mutation of the flavin binding domain

    Maklashina, E., Iverson, T. M., Sher, Y., Kotlyar, V., Andréll, J., Mirza, Osman Asghar, Hudson, J. M., Armstrong, F. A., Rothery, R. A., Weiner, J. H. & Cecchini, G., 21 Apr 2006, In: Journal of Biological Chemistry. 281, 16, p. 11357-65 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  82. Published

    Structural evidence for induced fit and a mechanism for sugar/H+ symport in LacY

    Mirza, Osman Asghar, Guan, L., Verner, G., Iwata, S. & Kaback, H. R., 22 Mar 2006, In: E M B O Journal. 25, 6, p. 1177-83 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  83. Published

    Crystal structure of the Glu328Gln mutant of Neisseria polysaccharea amylosucrase in complex with sucrose and maltoheptaose

    Skov, L. K., Mirza, Osman Asghar, Sprogøe, D., van der Veen, B., Remaud-Simeon, M., Albenne, C., Monsan, P. & Gajhede, Michael, 1 Jan 2006, In: Biocatalysis and Biotransformation. 24, 1-2, p. 99-105 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  84. Published

    Structural rearrangements of sucrose phosphorylase from Bifidobacterium adolescentis during sucrose conversion

    Mirza, Osman Asghar, Henriksen, L. S., Sprogøe, D., van den Broek, L. A. M., Beldman, G., Kastrup, Jette Sandholm Jensen & Gajhede, Michael, 2006, In: Journal of Biological Chemistry. 281, 46, p. 35576-84 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  85. Published

    The structure of a mixed GluR2 ligand-binding core dimer in complex with (S)-glutamate and the antagonist (S)-NS1209

    Kasper, C., Pickering, Darryl S, Mirza, Osman Asghar, Olsen, L., Kristensen, Anders Skov, Greenwood, J. R., Liljefors, T., Schousboe, Arne, Wätjen, F., Gajhede, Michael, Sigurskjold, B. W. & Kastrup, Jette Sandholm Jensen, 2006, In: Journal of Molecular Biology. 357, 4, p. 1184-201 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  86. 2004
  87. Published

    Crystal structure of the covalent intermediate of amylosucrase from Neisseria polysaccharea

    Jensen, M. H., Mirza, Osman Asghar, Albenne, C., Remaud-Simeon, M., Monsan, P., Gajhede, Michael & Skov, L., 23 Mar 2004, In: Biochemistry. 43, 11, p. 3104-10 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  88. Published

    Crystal structure of sucrose phosphorylase from Bifidobacterium adolescentis

    Sprogøe, D., van den Broek, L. A. M., Mirza, Osman Asghar, Kastrup, Jette Sandholm Jensen, Voragen, A. G. J., Gajhede, Michael & Skov, L., 10 Feb 2004, In: Biochemistry. 43, 5, p. 1156-62 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  89. Published

    Molecular basis of the amylose-like polymer formation catalyzed by Neisseria polysaccharea amylosucrase

    Albenne, C., Skov, L., Mirza, Osman Asghar, Gajhede, Michael, Feller, G., D'Amico, S., André, G., Potocki-Véronèse, G., van der Veen, B. A., Monsan, P. & Remaud-Simeon, M., 2 Jan 2004, In: Journal of Biological Chemistry. 279, 1, p. 726-34 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  90. 2003
  91. Published

    Rational and combinatorial engineering of the glucan synthesizing enzyme amylosucrase

    Albenne, C., Van Der Veen, B. A., Potocki-Véronèse, G., Joucla, G., Skov, L., Mirza, Osman Asghar, Gajhede, Michael, Monsan, P. & Remaud-Simeon, M., 1 Aug 2003, In: Biocatalysis and Biotransformation. 21, 4-5, p. 271-277 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  92. Published

    Dominating IgE-binding epitope of Bet v 1, the major allergen of birch pollen, characterized by X-ray crystallography and site-directed mutagenesis

    Spangfort, M. D., Mirza, Osman Asghar, Ipsen, H., Van Neerven, R. J. J., Gajhede, Michael & Larsen, J., 2003, In: Journal of Immunology. 171, 6, p. 3084-90 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  93. 2002
  94. Published

    Oligosaccharide and sucrose complexes of amylosucrase. Structural implications for the polymerase activity

    Skov, L. K., Mirza, Osman Asghar, Sprogøe, D., Dar, I., Remaud-Simeon, M., Albenne, C., Monsan, P. & Gajhede, Michael, 6 Dec 2002, In: Journal of Biological Chemistry. 277, 49, p. 47741-7 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  95. Published

    Site-directed mutagenesis of key amino acids in the active site of amylosucrase from Neisseria polysaccharea

    Albenne, C., Potocki De Montalk, G., Monsan, P., Skov, L., Mirza, Osman Asghar, Gajhede, Michael & Remaud-Simeon, M., 1 Dec 2002, In: Biologia - Section Cellular and Molecular Biology. 57, SUPPL. 11, p. 119-128 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  96. Published

    Maltooligosaccharide disproportionation reaction: an intrinsic property of amylosucrase from Neisseria polysaccharea

    Albenne, C., Skov, L. K., Mirza, Osman Asghar, Gajhede, Michael, Potocki-Véronèse, G., Monsan, P. & Remaud-Simeon, M., 11 Sep 2002, In: F E B S Letters. 527, 1-3, p. 67-70 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  97. 2001

  98. Crystal structures of amylosucrase from Neisseria polysaccharea in complex with D-glucose and the active site mutant Glu328Gln in complex with the natural substrate sucrose

    Mirza, Osman Asghar, Skov, L. K., Remaud-Simeon, M., Potocki de Montalk, G., Albenne, C., Monsan, P. & Gajhede, M., 31 Jul 2001, In: Biochemistry. 40, 30, p. 9032-9 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  99. Published

    Amylosucrase, a glucan-synthesizing enzyme from the alpha-amylase family

    Skov, L. K., Mirza, Osman Asghar, Henriksen, A., De Montalk, G. P., Remaud-Simeon, M., Sarçabal, P., Willemot, R. M., Monsan, P. & Gajhede, Michael, 6 Jul 2001, In: Journal of Biological Chemistry. 276, 27, p. 25273-8 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  100. Major venom allergen of yellow jackets, Ves v 5: structural characterization of a pathogenesis-related protein superfamily

    Henriksen, A., King, T. P., Mirza, Osman Asghar, Monsalve, R. I., Meno, K., Ipsen, H., Larsen, J. N., Gajhede, M. & Spangfort, M. D., 2001, In: Proteins: Structure, Function, and Bioinformatics. 45, 4, p. 438-48 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  101. Published

    Structure of soybean seed coat peroxidase: a plant peroxidase with unusual stability and haem-apoprotein interactions

    Henriksen, A., Mirza, Osman Asghar, Indiani, C., Teilum, Kaare, Smulevich, G., Welinder, K. G. & Gajhede, Michael, 2001, In: Protein Science. 10, 1, p. 108-15 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  102. 2000
  103. Published

    Dominant epitopes and allergic cross-reactivity: complex formation between a Fab fragment of a monoclonal murine IgG antibody and the major allergen from birch pollen Bet v 1

    Mirza, Osman Asghar, Henriksen, A., Ipsen, H., Larsen, J. N., Wissenbach, M., Spangfort, M. D. & Gajhede, Michael, 1 Jul 2000, In: Journal of Immunology. 165, 1, p. 331-8 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  104. Published

    Arabidopsis thaliana peroxidase N: structure of a novel neutral peroxidase

    Mirza, Osman Asghar, Henriksen, A., Ostergaard, L., Welinder, K. G. & Gajhede, Michael, Mar 2000, In: Acta Crystallographica. Section D: Biological Crystallography. 56, Pt 3, p. 372-5 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  105. Published

    Crystallization and preliminary X-ray studies of recombinant amylosucrase from Neisseria polysaccharea

    Skov, L. K., Mirza, Osman Asghar, Henriksen, A., Potocki de Montalk, G., Remaud-Simeon, M., Sarcabal, P., Willemot, R. M., Monsan, P. & Gajhede, M., Feb 2000, In: Acta Crystallographica. Section D: Biological Crystallography. 56, Pt 2, p. 203-5 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  106. Published

    Arabidopsis ATP A2 peroxidase. Expression and high-resolution structure of a plant peroxidase with implications for lignification.

    Ostergaard, L., Teilum, Kaare, Mirza, Osman Asghar, Mattsson, O., Petersen, M., Welinder, K. G., Mundy, J., Gajhede, Michael & Henriksen, A., 2000, In: Plant Molecular Biology. 44, 2, p. 231-43 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  107. 1999
  108. Published

    Crystallization and preliminary X-ray analysis of birch-pollen allergen Bet v 1 in complex with a murine monoclonal IgG Fab' fragment

    Spangfort, M. D., Mirza, Osman Asghar & Gajhede, Michael, Dec 1999, In: Acta Crystallographica. Section D: Biological Crystallography. 55, Pt 12, p. 2035-6 2 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

ID: 1302772