Signe Lykke Nielsen

Signe Lykke Nielsen

Biomedical Laboratory Scientist


  1. Published

    TOP1 gene copy numbers in colorectal cancer samples and cell lines and their association to in vitro drug sensitivity

    Rømer, M. U., Jensen, N. F., Nielsen, Signe Lykke, Müller, S., Nielsen, K. V., Nielsen, H. J. & Brünner, N., 2012, In: Scandinavian Journal of Gastroenterology. 47, 1, p. 68-79 12 p.

    Research output: Contribution to journalJournal articlepeer-review

  2. Published

    A phase II study of Epirubicin in oxaliplatin-resistant patients with metastatic colorectal cancer and TOP2A gene amplification

    Tarpgaard, L. S., Qvortrup, C., Nygård, S. B., Nielsen, Signe Lykke, Andersen, D. R., Jensen, N. F., Stenvang, Jan, Detlefsen, S., Brünner, N. & Pfeiffer, P., 2016, In: B M C Cancer. 16, 5 p., 91.

    Research output: Contribution to journalJournal articlepeer-review

  3. Published

    Assessment of the topoisomerase I gene copy number as a predictive biomarker of objective response to irinotecan in metastatic colorectal cancer

    Nygård, S. B., Christensen, I. J., Nielsen, Signe Lykke, Nielsen, H. J., Brünner, N. & Spindler, K. G., 2014, In: Scandinavian Journal of Gastroenterology. 49, 1, p. 84-91 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  4. Published

    DNA Topoisomerase I Gene Copy Number and mRNA Expression Assessed as Predictive Biomarkers for Adjuvant Irinotecan in Stage II/III Colon Cancer

    Nygård, S. B., Vainer, B., Nielsen, Signe Lykke, Bosman, F. T., Tejpar, S., Roth, A., Delorenzi, M., Brunner, N. & Budinska, E., 2016, In: Clinical Cancer Research. 22, 7, p. 1621-1631

    Research output: Contribution to journalJournal articlepeer-review

  5. Published

    Human epidermal growth factor receptor 2 (HER2) immunoreactivity: specificity of three pharmacodiagnostic antibodies

    Rasmussen, A. S., Pedersen, H. C., Jensen, S. S., Nielsen, Signe Lykke & Brünner, N., 2011, In: Histopathology. 59, 5, p. 975-983 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  6. Published

    MYC translocation partner gene determines survival of patients with large B-cell lymphoma with MYC- or double-hit MYC/BCL2 translocations

    Pedersen, M. Ø., Gang, A. O., Poulsen, T. S., Knudsen, H., Lauritzen, A. F., Nielsen, Signe Lykke, Klausen, T. W. & Nørgaard, P., Jan 2014, In: European Journal of Haematology. 92, 1, p. 42-48 7 p.

    Research output: Contribution to journalJournal articlepeer-review

  7. Published

    Modulation of Rat Cancer-Induced Bone Pain is Independent of Spinal Microglia Activity

    Diaz-delCastillo, M., Hansen, R. B., Appel, C. K., Nielsen, Signe Lykke, Nielsen, S. N., Karyniotakis, K., Dahl, L. M., Andreasen, R. B. & Heegaard, Anne-Marie, 2020, In: Cancers. 12, 10, 19 p., 2740.

    Research output: Contribution to journalJournal articlepeer-review

  8. Published

    Molecular characterization of irinotecan (SN-38) resistant human breast cancer cell lines

    Jandu, H., Aluzaité, K., Fogh, L., Thrane, S. W., Noer, J. B., Proszek, J., Nguyen Do, K., Hansen, S. N., Damsgaard-Hansen, B., Nielsen, S. L., Stougaard, M., Knudsen, B. R., Moreira, J., Hamerlik, P., Gajjar, M., Smid, M., Martens, J., Foekens, J., Pommier, Y., Brünner, N. & 2 others, Rasmussen, A. S. & Stenvang, Jan, 22 Jan 2016, In: B M C Cancer. 16, 13 p., 34.

    Research output: Contribution to journalJournal articlepeer-review

  9. Published

    TOP1 gene copy number and TOP1/CEN-20 ratio in stage III colorectal cancer samples

    Rømer, M. U. K., Nygård, S. B., Christensen, I. J., Hersi Smith, D., Vang Nielsen, K., Müller, S., Vainer, B., Nielsen, H. J., Nielsen, Signe Lykke & Brunner, N., 27 Apr 2012.

    Research output: Contribution to conferencePosterResearchpeer-review

  10. Published

    Topoisomerase 1(TOP1) gene copy number in stage III colorectal cancer patients and its relation to prognosis

    Rømer, M. U. K., Nygård, S. B., Christensen, I. J., Nielsen, Signe Lykke, Nielsen, K. V., Müller, S., Smith, D. H., Vainer, B., Nielsen, H. J. & Brünner, N., 2013, In: Molecular Oncology. 7, 1, p. 101-111 11 p.

    Research output: Contribution to journalJournal articlepeer-review

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