Stephan Pless

Stephan Pless

Professor

ORCID: 0000-0001-6654-114X

Publication year:
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1 - 25 out of 78Page size: 25
  1. 2024
  2. Accepted/In press

    Protein semisynthesis underscores the role of a conserved lysine in activation and desensitization of acid-sensing ion channels

    Sarkar, Debayan, Galleano, I., Heusser, Stephanie, Ou, S. Y., Uzun, G. R., Khoo, K. K., van der Heden van Noort, G. J., Harrison, J. S. & Pless, Stephan, 2024, (Accepted/In press) In: Cell Chemical Biology.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. 2023
  4. Published

    Functional modulation of a pH-sensitive ion channel by a transporter family

    Poulsen, Mette Homann, Xue, F., Maurya, S. R., Kickinger, Stefanie, Usher, Samuel George, Wellendorph, Petrine, Lundby, Alicia & Pless, Stephan, 2023, In: Biophysical Journal. 122, 3 Suppl. 1, p. 249a

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  5. Published

    Unravelling the functional regulation of the NALCN sodium leak channel complex by G protein-coupled receptors

    Harms, Hendrik & Pless, Stephan, 2023, In: Biophysical Journal. 122, 3 Suppl. 1, p. 163a

    Research output: Contribution to journal › Conference abstract in journal › Research

  6. 2022
  7. Published

    ATP signaling in pancreatic cancer: the P2X7 receptor

    Magni, Lara, Bouazzi, R., Christensen, Nynne, Tozzi, M., Poulsen, M., Johansen, J., Pless, Stephan & Novak, Ivana, 2022, In: Acta Physiologica. 236, S725, p. 661-661

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  8. Published

    Conformational decoupling in acidsensing ion channels uncovers mechanism and stoichiometry of PcTx1mediated inhibition

    Heusser, Stephanie, Borg, C. B., Colding, J. M. & Pless, Stephan, 2022, In: eLife. 11, 20 p., e73384.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    P2X2 receptor subunit interfaces are missense variant hotspots, where mutations tend to increase apparent ATP affinity

    Gasparri, F., Sarkar, Debayan, Bielickaite, S., Poulsen, Mette Homann, Hauser, Alexander Sebastian & Pless, Stephan, 2022, In: British Journal of Pharmacology. 179, 14, p. 3859-3874

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Structural architecture of the human NALCN channelosome

    Kschonsak, M., Chua, H. C., wbv551, wbv551, Chakouri, N., Noland, C. L., Schott, K., Chang, T., Tam, C., Patel, N., Arthur, C. P., Leitner, A., Ben-Johny, M., Ciferri, C., Pless, Stephan & Payandeh, J., 2022, In: Nature. 603, p. 180–186

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Structure-guided unlocking of NaX reveals a non-selective tetrodotoxin-sensitive cation channel

    Noland, C. L., Chua, H. C., Kschonsak, M., Heusser, Stephanie, Braun, N., Chang, T., Tam, C., Tang, J., Arthur, C. P., Ciferri, C., Pless, Stephan & Payandeh, J., 2022, In: Nature Communications. 13, 1, 10 p., 1416.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    The suitability of high throughput automated patch clamp for physiological applications

    Obergrussberger, A., Rinke-Weiß, I., Goetze, T. A., Rapedius, M., Brinkwirth, N., Becker, N., Rotordam, M. G., Hutchison, L., Madau, P., Pau, D., Dalrymple, D., Braun, N., Friis, S., Pless, Stephan & Fertig, N., 2022, In: Journal of Physiology. 600, 2, p. 277-297

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. 2021
  14. Published

    Acid-sensing ion channels as potential therapeutic targets

    Heusser, Stephanie & Pless, Stephan, 2021, In: Trends in Pharmacological Sciences. 42, 12, p. 1035-1050

    Research output: Contribution to journal › Review › Research › peer-review

  15. Published

    Characterizing Conformational Changes of ASIC1a During Gating and Peptide Modulation

    Heusser, Stephanie, Sheikh, Zeshan Pervez, Borg, C. B., Galleano, I. & Pless, Stephan, 2021, p. 337A-337A.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  16. Published

    Functional Characterization of Disease-Causing Mutations in the Sodium Leak Channel NALCN

    wbv551, wbv551, Ameen, A. O., Chua, H. C. & Pless, Stephan, 2021, p. 10A-11A.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  17. Published

    Functional cross-talk between phosphorylation and disease-causing mutations in the cardiac sodium channel Nav1.5

    Galleano, I., Harms, Hendrik, Choudhury, K., Khoo, K., Delemotte, L. & Pless, Stephan, 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 33, 10 p., e2025320118.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    High-throughput characterization of photocrosslinker-bearing ion channel variants to map residues critical for function and pharmacology

    Braun, N., Friis, S., Ihling, C., Sinz, A., Andersen, J. & Pless, Stephan, 2021, In: PLOS Biology. 19, 9, 30 p., e3001321.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Interplay of Nav1.5 Disease-Causing Mutations and Phosphorylation Revealed by Protein Semi-Synthesis and Molecular Dynamics Simulations

    Galleano, I., Harms, Hendrik, Choudhury, K., Khoo, K. K., Delemotte, L. & Pless, Stephan, 2021, p. 288A-288A.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  20. Published

    Ion channel engineering using protein trans-splicing

    Sarkar, Debayan, Harms, Hendrik, Galleano, I., Sheikh, Zeshan Pervez & Pless, Stephan, 2021, Methods in Enzymology. Elsevier, p. 19-48 30 p. (Methods in Enzymology).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  21. Published

    The M1 and pre-M1 segments contribute differently to ion selectivity in ASICs and ENaCs

    Sheikh, Zeshan Pervez, Wulf, M., Friis, S., Althaus, M., Lynagh, T. & Pless, Stephan, 2021, In: Journal of General Physiology. 153, 10, 23 p., e202112899.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    The gating pore blocker 1-(2,4-xylyl)guanidinium selectively inhibits pacemaking of midbrain dopaminergic neurons

    Jehasse, K., Massotte, L., Hartmann, S., Vitello, R., Ringlet, S., Vitello, M., Chua, H. C., Pless, Stephan, Engel, D., Liégeois, J. F., Lakaye, B., Roeper, J. & Seutin, V., 2021, In: Neuropharmacology. 197, 15 p., 108722.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. 2020
  24. Published

    Chemical modification of proteins by insertion of synthetic peptides using tandem protein trans-splicing

    Khoo, K. K., Galleano, I., Gasparri, F., Wieneke, R., Harms, Hendrik, Poulsen, Mette Homann, Chua, H. C., Wulf, M., Tampé, R. & Pless, Stephan, 1 Dec 2020, In: Nature Communications. 11, 1, 10 p., 2284.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    The NALCN channel complex is voltage sensitive and directly modulated by extracellular calcium

    Chua, H. C., Wulf, M., wbv551, wbv551, Rasmussen, L. P. & Pless, Stephan, Apr 2020, In: Science Advances. 6, 17, 11 p., aaz3154.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Mechanism and Binding Site of the ASIC1A-Big Dynorphin Interaction

    Borg, C. B., Braun, N., Heusser, Stephanie, Bay, Y., Weis, D., Galleano, I., Lund, Camilla, Tian, W., Haugaard-Kedstrom, L. M., Bennett, Eric Paul, Lynagh, T., Strømgaard, Kristian, Andersen, J. & Pless, Stephan, 7 Feb 2020, In: Biophysical Journal. 118, 3, supplement 1, p. 582A-582A

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  27. Published

    The Sodium Leak Channel Complex is Modulated by Voltage and Extracellular Calcium

    Chua, H. C., Wulf, M., wbv551, wbv551, Rasmussen, L. P. & Pless, Stephan, 7 Feb 2020, p. 499A-499A.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  28. Published

    Determinants of ion selectivity in ASIC1a- and ASIC2a-containing acid-sensing ion channels

    Lynagh, T., Flood, E., Boiteux, C., Sheikh, Zeshan Pervez, Allen, T. W. & Pless, Stephan, 3 Feb 2020, In: The Journal of general physiology. 152, 2

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Evolutionarily Conserved Interactions within the Pore Domain of Acid-Sensing Ion Channels

    Kasimova, M. A., Lynagh, T., Sheikh, Zeshan Pervez, Granata, D., Borg, C. B., Carnevale, V. & Pless, Stephan, 2020, In: Biophysical Journal. 118, 4, p. 861-872 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Mechanism and site of action of big dynorphin on ASIC1a

    Borg, C. B., Braun, N., Heusser, Stephanie, Bay, Y., Weis, D., Galleano, I., Lund, Camilla, Tian, W., Haugaard-Kedström, L. M., Bennett, Eric Paul, Lynagh, T., Strømgaard, Kristian, Andersen, J. & Pless, Stephan, 2020, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 13, p. 7447-7454

    Research output: Contribution to journal › Journal article › Research › peer-review

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ID: 93715174