Stephanie Heusser

Stephanie Heusser

Assistant Professor


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  1. Published

    Acid-sensing ion channels as potential therapeutic targets

    Heusser, Stephanie & Pless, Stephan, 2021, In: Trends in Pharmacological Sciences. 42, 12, p. 1035-1050

    Research output: Contribution to journal › Review › Research › peer-review

  2. Published

    Allosteric Gating Determinants in the Transmembrane Domain of Pentameric Ligand-Gated Ion Channels

    Howard, R. J., Zhuang, Y., Heusser, Stephanie, Bergh, C. C., Rovsnik, U., Orellana, L. & Lindahl, E., 2020, p. 584A-584A.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  3. Allosteric potentiation of a ligand-gated ion channel is mediated by access to a deep membrane-facing cavity

    Heusser, Stephanie, Lycksell, M., Wang, X., McComas, S. E., Howard, R. J. & Lindahl, E., 1 Oct 2018, (E-pub ahead of print) In: Proceedings of the National Academy of Sciences of the United States of America. 115, 42, p. 10672-10677

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Characterizing Conformational Changes of ASIC1a During Gating and Peptide Modulation

    Heusser, Stephanie, Sheikh, Zeshan Pervez, Borg, C. B., Galleano, I. & Pless, Stephan, 2021, p. 337A-337A.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  5. Published

    Conformational Landscapes of Ligand-Gated Ion Channel GLIC from Markov State Modeling

    Bergh, C., Heusser, Stephanie, Howard, R. J. & Lindahl, E. R., 2021, p. 58A-58A.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  6. Published

    Conformational decoupling in acidsensing ion channels uncovers mechanism and stoichiometry of PcTx1mediated inhibition

    Heusser, Stephanie, Borg, C. B., Colding, J. M. & Pless, Stephan, 2022, In: eLife. 11, 20 p., e73384.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Functional characterization of neurotransmitter activation and modulation in a nematode model ligand-gated ion channel

    Heusser, Stephanie, Yoluk, Ö., Klement, G., Riederer, E. A., Lindahl, E. & Howard, R. J., Jul 2016, In: Journal of Neurochemistry. 138, 2, p. 243-53 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Functional validation of virtual screening for novel agents with general anesthetic action at ligand-gated ion channels

    Heusser, Stephanie, Howard, R. J., Borghese, C. M., Cullins, M. A., Broemstrup, T., Lee, U. S., Lindahl, E., Carlsson, J. & Harris, R. A., Nov 2013, In: Molecular Pharmacology. 84, 5, p. 670-8 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Markov state models of proton- and pore-dependent activation in a pentameric ligand-gated ion channel

    Bergh, C., Heusser, Stephanie, Howard, R. & Lindahl, E., 2021, In: eLife. 10, 23 p., 68369.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Mechanism and Binding Site of the ASIC1A-Big Dynorphin Interaction

    Borg, C. B., Braun, N., Heusser, Stephanie, Bay, Y., Weis, D., Galleano, I., Lund, Camilla, Tian, W., Haugaard-Kedstrom, L. M., Bennett, Eric Paul, Lynagh, T., Strømgaard, Kristian, Andersen, J. & Pless, Stephan, 7 Feb 2020, In: Biophysical Journal. 118, 3, supplement 1, p. 582A-582A

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

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