Invited Lecture: From Host Defence Peptides to New Antibiotics
Research output: Contribution to conference › Conference abstract for conference › Research
Antimicrobial peptides hold promise as the next generation of antimicrobial agents. However, the potential is weakened by their susceptibility to proteolytic degradation, poor bioavailabillity , toxicity and high cost. Our research interest is in determining the structure/activity relationships of these antimicrobial peptides, which enables us to better understand their mechanism of action and facilitates the development of lead antimicrobial agents. As an example, in this talk I will focus on our work on anoplin and analogues, a decapeptide isolated from the Japanese wasp Anoplius samariensis. I will describe the elucidation of their structure/activity relationships, and our efforts towards developing them into antibiotics.
Original language | English |
---|---|
Publication date | 2014 |
Publication status | Published - 2014 |
Event | Antibiotic alternatives for the new millennium - London, London, United Kingdom Duration: 5 Nov 2014 → 7 Nov 2014 |
Conference
Conference | Antibiotic alternatives for the new millennium |
---|---|
Location | London |
Country | United Kingdom |
City | London |
Period | 05/11/2014 → 07/11/2014 |
ID: 127141479