Kristensen Group

Medicinal Chemistry

The design and synthesis of new ligands is at the core of our research

Research Focus

Generally medicinal chemistry and the development of new methodology for the construction of compound classes of relevance to medicinal chemistry. Using these tools we are trying to develop new probes and tools that will help us to elucidate the underlying mechanisms responsible for the regulation of different pharmacological targets: Ion channels, enzymes and GPCR’s.

5-HT2A Agonists

We are developing new selective

ligands for the Serotonin 2A receptor

Erythrina Alkaloids

We are designing new ligands

based on natural products


We are developing new imaging agents

Within the Marie Curie Training network SAFER we are striving to develop new functionallyselective ligands for the Serotonine 2A receptor.

For more information see:

Within the Horizon2020 project Click-It we are developing new imaging technology to improve clinical companion diagnostics for cancer patients.

For more information see: 

The ETN- network PET-AlphasSy strives to develop α-synuclein PET tracers to diagnose and monitor and Parkinson’s Disease.

For more information see:

Master projects

We offer a wide variety of different projects within the areas of organic/total synthesis, Medicinal Chemistry and Radiopharmaceuticals/PET-ligands. Please contact Jesper L. Kristensen for further info - we are always looking for new talent to join the group.

Examples of Recent Master projects

Emil Glibstrup: Synthetic strategies towards the CD-rings of DHBE.
Morten Borch: Synthesis and Biological Evaluation of Erythrina Alkaloid Analogues.
Ida Nymann Petersen: Total Synthesis of Pyridoacridines.
Sebastian Leth-Petersen: Synthetic tools for the study of consciousness.

Studieretningsprojekter (SRP):

Each fall we offer projects for highschool student where they get the chance to visit our labs and synthesize a drug molecule, more info here (in Danish) SRP


Please see GoogleScholar or ResearchGate for an updated list of publications.