Jesper Langgaard Kristensen
Professor
Medicinal Chemistry
Jagtvej 162
2100 København Ø
- 2024
- E-pub ahead of print
Discovery and Structure-Activity Relationships of 2,5-Dimethoxyphenylpiperidines as Selective Serotonin 5-HT2A Receptor Agonists
Marcher, Emil, Jensen, Anders A., Smits, G., Frydenvang, Karla Andrea & Kristensen, Jesper Langgaard, 2024, (E-pub ahead of print) In: Journal of Medicinal Chemistry.Research output: Contribution to journal › Journal article › Research › peer-review
- 2023
- Published
Er psykedeliske stoffer uden bivirkninger mulige?
Kristensen, Jesper Langgaard, 16 Mar 2023, Videnskab.dk.Research output: Other contribution › Net publication - Internet publication › Communication
- Published
In Vitro and In Vivo Evaluation of Pellotine: A Hypnotic Lophophora Alkaloid
Poulie, C. B. M., Chan, C. B., Parka, A., Lettorp, M., Vos, J., Raaschou, A., Pottie, E., Bundgaard, M. S., Sørensen, L. M. E., Cecchi, C. R., Märcher-Rørsted, E., Bach, A., Herth, M. M., Decker, A., Jensen, A. A., Elfving, B., Kretschmann, A. C., Stove, C. P., Kohlmeier, K. A., Cornett, C. & 3 others, , 2023, In: ACS Pharmacology & Translational Science. 6, 10, p. 1492-1507Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Introducing Conformational Restraints on 25CN-NBOH: A Selective 5-HT2A Receptor Agonist
Marcher, Emil, Nykodemová, J., Harpsøe, Kasper, Jensen, Anders A. & Kristensen, Jesper Langgaard, 2023, In: ACS Medicinal Chemistry Letters. 14, 3, p. 319–325Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Overcoming Energy Transfer for the Metallophotoredox Catalyzed Decarboxylative Alkenylation between Alkylcarboxylic Acids and Enol Triflates
Pedersen, S. K., Clementson, S., Kristensen, Jesper Langgaard, Jessing, M. & El-Chami, K., 2023, In: Chemistry: A European Journal. 29, 35, e202300265.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structure–Activity Assessment and In-Depth Analysis of Biased Agonism in a Set of Phenylalkylamine 5-HT2A Receptor Agonists
Pottie, E., Poulie, Christian Bernard Matthijs, Simon, Icaro A, Harpsøe, Kasper, D’Andrea, L., Komarov, I. V., Gloriam, David E., Jensen, Anders A., Kristensen, Jesper Langgaard & Stove, C. P., 2023, In: ACS Chemical Neuroscience. 14, 15, p. 2727–2742Research output: Contribution to journal › Journal article › Research › peer-review
- 2022
- Published
Animal Behavior in Psychedelic Research
Odland, Anna Ulstein, Kristensen, Jesper Langgaard & Andreasen T., Jesper, 2022, In: Pharmacological Reviews. 74, 4, p. 1176-1205 30 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Discovery of β-Arrestin-Biased 25CN-NBOH-Derived 5-HT2A Receptor Agonists
Poulie, Christian Bernard Matthijs, Pottie, E., Simon, Icaro A, Harpsøe, Kasper, D'Andrea, L., Komarov, I. V., Gloriam, David E., Jensen, Anders A., Stove, C. P. & Kristensen, Jesper Langgaard, 2022, In: Journal of Medicinal Chemistry. 65, 18, p. 12031–12043Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Funnel metadynamics and behavioral studies reveal complex effect of D2AAK1 ligand on anxiety-like processes
Bartuzi, D., Kędzierska, E., Targowska-Duda, K. M., Koszła, O., Wróbel, T. M., Jademyr, S., Karcz, T., Szczepańska, K., Stępnicki, P., Wronikowska-Denysiuk, O., Biała, G., Handzlik, J., Kristensen, Jesper Langgaard, Poso, A. & Kaczor, A. A., 2022, In: Scientific Reports. 12, 1, 14 p., 21192.Research output: Contribution to journal › Journal article › Research › peer-review
- 2021
- Published
25CN-NBOH: A selective agonist for in vitro and in vivo investigations of the serotonin 2A receptor
Marcher, Emil, Jensen, Anders A. & Kristensen, Jesper Langgaard, 2021, In: ChemMedChem. 16, 21, p. 3263-3270Research output: Contribution to journal › Review › Research › peer-review
- Published
A quantitative method for the selective 5-HT2A agonist 25CN-NBOH in rat plasma and brain
Breusova, K., Ernstsen, K. G., Palner, M., Linnet, Kristian, Kristensen, Jesper Langgaard & Kretschmann, A. C., 2021, In: Journal of Pharmaceutical and Biomedical Analysis. 199, 114016.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An improved, scalable synthesis of the selective serotonin 2A receptor agonist 25CN-NBOH
Marcher, Emil, Nykodemova, J. & Kristensen, Jesper Langgaard, 2021, In: SynOpen. 5, 2, p. 158-160Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Desorption Electrospray Ionization Mass Spectrometry Imaging of Cimbi-36, a 5-HT2A Receptor Agonist, with Direct Comparison to Autoradiography and Positron Emission Tomography
Jacobsen, S. C., Speth, N. R., Xiong, M., Herth, Matthias Manfred, Kristensen, Jesper Langgaard, Palner, M. & Janfelt, Christian, 2021, In: Molecular Imaging and Biology. 23, p. 676–685Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Direct Cu-mediated aromatic18F-labeling of highly reactive tetrazines for pretargeted bioorthogonal PET imaging
García-Vázquez, R., Battisti, Umberto Maria, Jørgensen, Jesper Tranekjær, Shalgunov, Vladimir, Hvass, Lars, Stares, D. L., Petersen, I. N., Crestey, F., Löffler, A., Svatunek, D., Kristensen, Jesper Langgaard, Mikula, H., Kjær, Andreas & Herth, Matthias Manfred, 2021, In: Chemical Science. 12, 35, p. 11668-11675Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Erythrina Alkaloid Analogues as nAChR Antagonists-A Flexible Platform for Leads in Drug Discovery
Clementson, S., Matheu, S. A., Marcher, Emil, Pedersen, H., Jensen, Anders A., Clausen, Rasmus Prætorius, Vital, P., Glibstrup, E., Jessing, M. & Kristensen, Jesper Langgaard, 2021, In: The Journal of Organic Chemistry. 86, 12, p. 8248-8262Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Investigating the role of 5-HT2A and 5-HT2C receptor activation in the effects of psilocybin, DOI, and citalopram on marble burying in mice
Odland, Anna Ulstein, Kristensen, Jesper Langgaard & Andreasen T., Jesper, 2021, In: Behavioural Brain Research. 401, 5 p., 113093.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lipophilicity and Click Reactivity Determine the Performance of Bioorthogonal Tetrazine Tools in Pretargeted In Vivo Chemistry
Steen, E. J. L., Jørgensen, Jesper Tranekjær, Denk, C., Battisti, Umberto Maria, Norregaard, K., Edem, P. E., Bratteby, K., Shalgunov, Vladimir, Wilkovitsch, M., Svatunek, D., Poulie, Christian Bernard Matthijs, Hvass, Lars, Simon, M., Wanek, T., Rossin, R., Robillard, M., Kristensen, Jesper Langgaard, Mikula, H., Kjær, Andreas & Herth, Matthias Manfred, 2021, In: ACS Pharmacology & Translational Science. 4, 2, p. 824-833 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The 5-hydroxytryptamine 2A receptor agonists DOI and 25CN-NBOH decrease marble burying and reverse 8-OH-DPAT-induced deficit in spontaneous alternation
Odland, Anna Ulstein, Jessen, L., Kristensen, Jesper Langgaard, Fitzpatrick, C. M. & Andreasen T., Jesper, 2021, In: Neuropharmacology. 183, 9 p., 107838.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Alkaloids from Lophophora diffusa and Other “False Peyotes”
Chan, Camilla Bachmand, Poulie, Christian Bernard Matthijs, Wismann, S. S., Soelberg, Jens & Kristensen, Jesper Langgaard, 2021, In: Journal of Natural Products. 84, 8, p. 2398–2407Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The selective 5-HT2A receptor agonist 25CN-NBOH does not affect reversal learning in mice
Odland, Anna Ulstein, Kristensen, Jesper Langgaard & Andreasen T., Jesper, 2021, In: Behavioural Pharmacology. 32, 5, p. 448-452Research output: Contribution to journal › Journal article › Research › peer-review
- 2020
- Published
Development of a Divergent Route to Erythrina Alkaloids
Clementson, S., Jessing, M., Vital, P. J. & Kristensen, Jesper Langgaard, 3 Mar 2020, In: Synlett. 31, 4, p. 327-333 7 p., st-2019-a0679-a.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In vivo effects of 3,4-methylenedioxymethamphetamine (MDMA) and its deuterated form in rodents: Drug discrimination and thermoregulation
Berquist, M. D., Leth-Petersen, S., Kristensen, Jesper Langgaard & Fantegrossi, W. E., 1 Mar 2020, In: Drug and Alcohol Dependence. 208, 8 p., 107850.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dark Classics in Chemical Neuroscience: NBOMes
Poulie, Christian Bernard Matthijs, Jensen, Anders A., Halberstadt, A. & Kristensen, Jesper Langgaard, 2020, In: ACS Chemical Neuroscience. p. 3860–3869 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Diclofenac prodrugs for intra-articular depot injectables: In vitro hydrolysis and species variation
Storgaard, Ida Klitzing, Kristensen, Jesper Langgaard, Larsen, C., Mertz, Nina, Østergaard, Jesper & Larsen, Susan Weng, 2020, In: Journal of Pharmaceutical Sciences. 109, 4, p. P1529-1536Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Direct Aromatic F-18-labeling of Tetrazines: A Rapid and Convenient Entry to Tetrazines for Pretargeted PET Imaging [Meeting Abstract]
Vazquez, R. G., Battisti, Umberto Maria, Stares, D. L., Petersen, I. N., Crestey, F., Svatunek, D., Mikula, H., Kristensen, Jesper Langgaard, Kjær, Andreas & Herth, Matthias Manfred, 2020, In: Journal of Nuclear Medicine. 61, Supl. 1, 2 p., 134.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
ID: 1305029
Most downloads
-
548
downloads
Convenient access to F-18-labeled amines through the Staudinger reduction
Research output: Contribution to journal › Conference abstract in journal › Research
Published -
327
downloads
A strategic approach to [6,6]-bicyclic lactones: application towards the CD fragment of DHβE
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
222
downloads
Substrate- and Cofactor-independent Inhibition of Histone Demethylase KDM4C
Research output: Contribution to journal › Journal article › Research › peer-review
Published