José Moreira
Professor
Translational and Clinical Pharmacology
Jagtvej 160
2100 København Ø
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Co-expression of TIMP-1 and its cell surface binding partner CD63 in glioblastomas
Aaberg-Jessen, C., Sørensen, M. D., Matos, A. L. S. A., Moreira, José, Brünner, N., Møldrup Knudsen, A. & Kristensen, B. W., 9 Mar 2018, In: BMC Cancer. 18, 16 p., 270.Research output: Contribution to journal › Journal article › Research › peer-review
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The net acid extruders NHE1, NBCn1 and MCT4 promote mammary tumor growth through distinct but overlapping mechanisms
Andersen, Anne Poder, Samsøe-Petersen, Jacob, Ørnbo, E. K., Bødtkjer, E., Moreira, José, Kveiborg, Marie & Pedersen, Stine Helene Falsig, 2018, In: International Journal of Cancer. 142, 12, p. 2529-2542 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Interactions of ion transporters and channels with cancer cell metabolism and the tumour microenvironment
Andersen, Anne Poder, Moreira, José & Pedersen, Stine Helene Falsig, 2014, In: Philosophical Transactions of the Royal Society B: Biological Sciences. 369, 1638, 11 p., 20130098.Research output: Contribution to journal › Journal article › Research › peer-review
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Proteomic Profiling of Colorectal Adenomas Identifies a Predictive Risk Signature for Development of Metachronous Advanced Colorectal Neoplasia
Bech, J. M., Terkelsen, Thilde Bagger, Bartels, Annette Snejbjerg, Coscia, F., Doll, S., Zhao, S., Zhang, Z., Brünner, N., Lindebjerg, J., Madsen, G. I., Fang, X., Mann, Matthias & Moreira, José, 2023, In: Gastroenterology. 165, 1, p. 121-132.e5Research output: Contribution to journal › Journal article › Research › peer-review
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Release of transcriptional repression via ErbB2-induced, SUMO-directed phosphorylation of myeloid zinc finger-1 serine 27 activates lysosome redistribution and invasion
Brix, D. M., Tvingsholm, S. A., Hansen, M. B., Clemmensen, K. B., Ohman, T., Siino, V., Lambrughi, M., Hansen, K., Puustinen, P., Gromova, I., James, P., Papaleo, E., Varjosalo, M., Moreira, José, Jäättelä, M. & Kallunki, Tuula Anneli, 2019, In: Oncogene. 38, p. 3170-3184Research output: Contribution to journal › Journal article › Research › peer-review
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Contribution of Na+,HCO3--cotransport to cellular pH control in human breast cancer: a role for the breast cancer susceptibility locus NBCn1 (SLC4A7)
Bødtkjer, E., Moreira, José, Mele, M., Vahl, P., Wielenga, V. T., Christiansen, P. M., Jensen, V. E. D., Pedersen, Stine Helene Falsig & Aalkjær, C., 2013, In: International Journal of Cancer. 132, 6, p. 1288-1299 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Proteomic profiling of triple-negative breast carcinomas in combination with a three-tier orthogonal technology approach identifies Mage-A4 as potential therapeutic target in estrogen receptor negative breast cancer
Cabezón, T., Gromova, I., Gromov, P., Serizawa, R. R., Wielenga, V. T., Kroman, Niels Thorndahl, Celis, J. E. & Moreira, José, 2013, In: Molecular & Cellular Proteomics. 12, 2, p. 381-394 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Characterization of breast precancerous lesions and myoepithelial hyperplasia in sclerosing adenosis with apocrine metaplasia
Celis, J. E., Gromova, I., Cabezón, T., Gromov, P., Shen, T., Timmermans, V. J. M., Rank, F. & Moreira, José, 2007, In: Molecular Oncology. 1, 1, p. 97-119 23 p.Research output: Contribution to journal › Journal article › Research
Identification of extracellular and intracellular signaling components of the mammary adipose tissue and its interstitial fluid in high risk breast cancer patients: Toward dissecting the molecular circuitry of epithelial-adipocyte stromal cell interactions
Celis, J. E., Cabezón, T., Gromov, P., Friis, E., Rank, F., Gromova, I. & Moreira, José, 1 Apr 2005, In: Molecular and Cellular Proteomics. 4, 4, p. 492-522 31 p.Research output: Contribution to journal › Journal article › Research
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Molecular characterization of apocrine carcinoma of the breast: validation of an apocrine protein signature in a well-defined cohort
Celis, J. E., Cabezon, T., Moreira, José, Gromov, P., Gromova, I., Timmermans-Wielenga, V., Iwase, T., Akiyama, F., Honma, N. & Rank, F., 2009, In: Molecular Oncology. 3, 3, p. 220-37Research output: Contribution to journal › Journal article › Research › peer-review
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Molecular pathology of breast apocrine carcinomas: A protein expression signature specific for benign apocrine metaplasia
Celis, J. E., Gromova, I., Gromov, P., Cabezón, T., Friis, E., Rank, F. & Moreira, José, 2006, In: FEBS Letters. 580, 12, p. 2935-2944 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Proteomic characterization of the interstitial fluid perfusing the breast tumor microenvironment: a novel resource for biomarker and therapeutic target discovery
Celis, J. E., Gromov, P., Cabezón, T., Moreira, José, Ambartsumian, N., Sandelin, K., Rank, F. & Gromova, I., 2004, In: Molecular and Cellular Proteomics. 3, 4, p. 327-44 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Integrating proteomic and functional genomic technologies in discovery-driven translational breast cancer research
Celis, J. E., Gromov, P., Gromova, I., Moreira, J. M. A., Cabezón, T., Ambartsumian, N., Grigorian, M., Lukanidin, E., Thor Straten, P., Guldberg, P., Bartkova, J., Bartek, J., Lukas, J., Lukas, C., Lykkesfeldt, A., Jäättelä, M., Roepstorff, P., Bolund, L., Ørntoft, T. F., Brünner, N. & 5 others, , 2003, In: Molecular and Cellular Proteomics. 2, 6, p. 369-377 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Impact of proteomics on bladder cancer research
Celis, J. E., Gromova, I., Moreira, José, Cabezon, T. & Gromov, P., 2004, In: Pharmacogenomics. 5, 4, p. 381-94 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Determination of Antibody Specificity by Western Blotting
Celis, J. E., Moreira, José & Gromov, P., 1 Dec 2006, Cell Biology, Four-Volume Set. Elsevier Science Inc., Vol. 1. p. 527-532 6 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Molecular Oncology journal has moved to open access
Celis, J. E. & Moreira, José, 1 Feb 2017, In: Molecular Oncology. 11, 2, 1 p.Research output: Contribution to journal › Editorial › Research › peer-review
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Clinical proteomics
Celis, J. E. & Moreira, José, 1 Oct 2008, In: Molecular and Cellular Proteomics. 7, 10, 1 p.Research output: Contribution to journal › Editorial › Research › peer-review
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Apocrine cysts of the breast: Biomarkers, origin, enlargement, and relation with cancer phenotype
Celis, J. E., Gromov, P., Moreira, José, Cabezón, T., Friis, E., Vejborg, I. M. M., Proess, G., Rank, F. & Gromova, I., 1 Mar 2006, In: Molecular and Cellular Proteomics. 5, 3, p. 462-483 22 p.Research output: Contribution to journal › Review › Research › peer-review
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Towards discovery-driven translational research in breast cancer
Celis, J. E., Moreira, José, Gromova, I., Cabezon, T., Ralfkiaer, U., Guldberg, P., Thor Straten, P., Mouridsen, H., Friis, E., Holm, D., Rank, F. & Gromov, P., 1 Jan 2005, In: FEBS Journal. 272, 1, p. 2-15 14 p.Research output: Contribution to journal › Review › Research › peer-review
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Identification of a subset of breast carcinomas characterized by expression of cytokeratin 15: Relationship between CK15+ progenitor/amplified cells and pre-malignant lesions and invasive disease
Celis, J. E., Gromova, I., Cabezón, T., Gromov, P., Shen, T., Timmermans-Wielenga, V., Rank, F. & Moreira, José, 1 Jan 2007, In: Molecular Oncology. 1, 3, p. 321-349 29 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Challenges and Opportunities in Oncoproteomics
Celis, J. E. & Moreira, José, 1 Jan 2010, In: Molecular Oncology. 4, 6, p. 459-460 2 p.Research output: Contribution to journal › Editorial › Research › peer-review
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Elucidation of Altered Pathways in Tumor-Initiating Cells of Triple-Negative Breast Cancer: A Useful Cell Model System for Drug Screening
Christensen, A. G., Ehmsen, S., Terp, M. G., Batra, R., Alcaraz, N., Baumbach, J., Noer, Julie Boertmann, Moreira, José, Leth-Larsen, R., Larsen, M. R. & Ditzel, H. J., 2017, In: Stem Cells. 35, 8, p. 1898-1912Research output: Contribution to journal › Journal article › Research › peer-review
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A streamlined mass spectrometry-based proteomics workflow for large scale FFPE tissue analysis
Coscia, F., Doll, S., Bech, J. M., Schweizer, L., Mund, Andreas, Lengyel, E., Lindebjerg, J., Madsen, G. I., Moreira, José & Mann, Matthias, 2020, In: Journal of Pathology. 251, p. 110-112Research output: Contribution to journal › Journal article › Research › peer-review
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Comparative analysis of evolutionarily conserved motifs of epidermal growth factor receptor 2 (HER2) predicts novel potential therapeutic epitopes
Deng, X., Zheng, X., Yang, H., Moreira, José, Brünner, N. & Christensen, Henrik, 2014, In: PLOS ONE. 9, 9, 9 p., e106448.Research output: Contribution to journal › Journal article › Research › peer-review
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Tissue Inhibitor of Metalloproteinases-1 Interacts with CD74 to Promote AKT Signaling, Monocyte Recruitment Responses, and Vascular Smooth Muscle Cell Proliferation
Ebert, S., Zang, L., Ismail, N., Otabil, M., Fröhlich, A., Egea, V., Ács, S., Hoeberg, M., Berres, M. L., Weber, C., Moreira, José, Ries, C., Bernhagen, J. & El Bounkari, O., 2023, In: Cells. 12, 14, 24 p., 1899.Research output: Contribution to journal › Journal article › Research › peer-review
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Proteogenomic characterization of patient-derived xenografts highlights the role of REST in neuroendocrine differentiation of castration-resistant prostate cancer
Flores-Morales, A., Bergmann, T. B., Lavallee, C., Batth, T. S., Lin, D., Lerdrup, M., Friis, S., Bartels, A., Kristensen, G., Krzyzanowska, A., Xue, H., Fazli, L., Hansen, K., Røder, M. A., Brasso, K., Moreira, J. M., Bjartell, A., Wang, Y., Olsen, J. V., Collins, C. C. & 1 others, , 2019, In: Clinical Cancer Research. 25, 2, p. 1-15Research output: Contribution to journal › Journal article › Research › peer-review
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A single lysis solution for the analysis of tissue samples by different proteomic technologies
Gromov, P., Celis, J. E., Gromova, I., Rank, F., Timmermans, V. J. M. & Moreira, José, 2008, In: Molecular Oncology. 2, 4, p. 368-379 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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FABP7 and HMGCS2 are novel protein markers for apocrine differentiation categorizing apocrine carcinoma of the breast
Gromov, P., Espinoza, J. A., Talman, M., Honma, N., Kroman, N., Wielenga, V. T., Moreira, José & Gromova, I., 2014, In: P L o S One. 9, 11, 14 p., e112024.Research output: Contribution to journal › Journal article › Research › peer-review
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Tumor interstitial fluid: a treasure trove of cancer biomarkers
Gromov, P., Gromova, I., Olsen, C. J., Timmermans-Wielenga, V., Talman, M., Serizawa, R. R. & Moreira, José, 2013, In: B B A - Proteins and Proteomics. 1834, 11, p. 2259-2270 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Proteomic analysis of tissue samples in translational breast cancer research
Gromov, P., Moreira, José & Gromova, I., 2014, In: Expert Review of Proteomics. 11, 3, p. 285-302 18 p.Research output: Contribution to journal › Review › Research › peer-review
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Proteomic analysis of urinary fibrinogen degradation products in patients with urothelial carcinomas
Gromov, P., Moreira, José, Gromova, I. & Celis, J. E., 1 Mar 2006, In: Clinical Proteomics. 2, 1-2, p. 45-66 22 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Proteomic strategies in bladder cancer: From tissue to fluid and back
Gromov, P., Moreira, José, Gromova, I. & Celis, J. E., 1 Jul 2008, In: Proteomics - Clinical Applications. 2, 7-8, p. 974-988 15 p.Research output: Contribution to journal › Review › Research › peer-review
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Immunoexpression analysis and prognostic value of BLCAP in breast cancer
Gromova, I., Gromov, P., Kroman, N., Wielenga, V. T., Simon, R., Sauter, G. & Moreira, José, 2012, In: P L o S One. 7, 9, 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Identification of BLCAP as a novel STAT3 interaction partner in bladder cancer
Gromova, I., Svensson, S., Gromov, P. & Moreira, José, 2017, In: PloS one. 12, 11, 18 p., e0188827.Research output: Contribution to journal › Journal article › Research › peer-review
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Functional proteomic profiling of triple-negative breast cancer
Gromova, I., Espinoza, J. A., Grauslund, M., Santoni Rugiu, Eric, Talman, M. L. M., van Oostrum, J. & Moreira, José, 2021, In: Cells. 10, 10, 14 p., 2768.Research output: Contribution to journal › Journal article › Research › peer-review
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High level PHGDH expression in breast is predominantly associated with keratin 5-positive cell lineage independently of malignancy
Gromova, I., Gromov, P., Honma, N., Kumar, S., Rimm, D., Talman, M. M., Wielenga, V. T. & Moreira, José, 2015, In: Molecular Oncology. 9, 8, p. 1636-1654 19 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The stepwise evolution of the exome during acquisition of docetaxel resistance in breast cancer cells
Hansen, S. N., Ehlers, Natasja Spring, Zhu, S., Thomsen, M. B. H., Nielsen, R. L., Liu, D., Wang, G., Hou, Y., Zhang, X., Xu, X., Bolund, L., Yang, H., Wang, J., Moreira, José, Ditzel, H. J., Brünner, N., Rasmussen, A. S., Stenvang, Jan & Gupta, R., 9 Jun 2016, In: B M C Genomics. 17, 15 p., 442.Research output: Contribution to journal › Journal article › Research › peer-review
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Acquisition of docetaxel resistance in breast cancer cells reveals upregulation of ABCB1 expression as a key mediator of resistance accompanied by discrete upregulation of other specific genes and pathways
Hansen, S. N., Westergaard, David, Thomsen, M. B. H., Vistesen, M. V., Do, K. N., Fogh, L., Belling, K. G., Wang, J., Yang, H., Gupta, R., Ditzel, H. J., Moreira, José, Brünner, N., Stenvang, Jan & Rasmussen, A. S., 2015, In: Tumor Biology. 36, 6, p. 4327-4338 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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TIMP-1 increases expression and phosphorylation of proteins associated with drug resistance in breast cancer cells
Hekmat, O., Munk, S., Fogh, L., Yadav, R., Francavilla, C., Horn, H., Würtz, S. Ø., Schrohl, A-S., Damsgaard, B., Romer, M. U., Belling, K., Jensen, N. F., Gromova, I., Bekker-Jensen, D. B., Moreira, J., Jensen, L. J., Gupta, R., Lademann, U. A., Brünner, N., Olsen, J. V. & 1 others, , 5 Aug 2013, In: Journal of Proteome Research. 12, 9, p. 4136-4151 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The invariant chain CD74 protein is a cell surface binding partner of TIMP-1 in breast cancer cells
Høeberg, M., Noer, Julie Boertmann, Vistesen, M. V., Bartels, Annette Snejbjerg, Bech, E. M., Nygård, S. B., Lademann, U., Stenvang, Jan, Liu, S., Fuglsang, Anja Thoe, Brünner, N. & Moreira, José, 2023, In: Molecular Oncology. 17, 8, p. 1595-1612Research output: Contribution to journal › Journal article › Research › peer-review
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Molecular characterization of irinotecan (SN-38) resistant human breast cancer cell lines
Jandu, H., Aluzaité, K., Fogh, L., Thrane, S. W., Noer, J. B., Proszek, J., Nguyen Do, K., Hansen, S. N., Damsgaard-Hansen, B., Nielsen, S. L., Stougaard, M., Knudsen, B. R., Moreira, J., Hamerlik, P., Gajjar, M., Smid, M., Martens, J., Foekens, J., Pommier, Y., Brünner, N. & 2 others, , 22 Jan 2016, In: B M C Cancer. 16, 13 p., 34.Research output: Contribution to journal › Journal article › Research › peer-review
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Purification and characterization of bioactive his6-tagged recombinant human tissue inhibitor of metalloproteinases-1 (TIMP-1) protein expressed at high yields in mammalian cells
Jensen, L. V., Lademann, U. A., Andersen, E. V., Højrup, P., Thaysen-Andersen, M., Krogh, B. O., Viuff, B. M., Brünner, N., Stenvang, Jan & Moreira, José, 2014, In: Protein Expression and Purification. 101, p. 157-164 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Establishment and characterization of models of chemotherapy resistance in colorectal cancer: towards a predictive signature of chemoresistance
Jensen, N. F., Stenvang, J., Beck, M. K., Hanáková, B., Belling, K. C., Do, K. N., Viuff, B. M., Nygård, S. B., Gupta, R., Rasmussen, M. H., Tarpgaard, L. S., Hansen, T. P., Budinská, E., Pfeiffer, P., Bosman, F., Tejpar, S., Roth, A., Delorenzi, M., Andersen, C. L., Rømer, M. U. K. & 2 others, , 24 Feb 2015, In: Molecular Oncology. 9, 6, p. 1169-1185 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Predictive value of combined analysis of pro-NPY and ERG in localized prostate cancer
Kristensen, G., Røder, Andreas, Berg, K. D., Elversang, J., Iglesias Gato, Diego, Moreira, José, Toft, B. G. & Brasso, K., 2018, In: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica. 126, 10, p. 804-813Research output: Contribution to journal › Journal article › Research › peer-review
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Topoisomerase-1 gene copy aberrations are frequent in patients with breast cancer
Kümler, I., Balslev, E., Poulsen, T. S., Nielsen, Signe Lykke, Nygård, S. B., Rømer, M. U., Christensen, I. J., Høgdall, E., Moreira, José, Nielsen, Dorte Lisbet, Brünner, N. & Stenvang, Jan, 8 Apr 2015, In: International Journal of Cancer. 137, 8, p. 2000-2006 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Drug transporters in breast cancer: response to anthracyclines and taxanes
Kümler, I., Stenvang, Jan, Moreira, José, Brünner, N. & Nielsen, Dorte Lisbet, Sep 2015, In: Expert Review of Anticancer Therapy. 15, 9, p. 1075-1092 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Itraconazole Reverts ABCB1-Mediated Docetaxel Resistance in Prostate Cancer
Lima, T. S., De Oliveira Souza, Luciano, Iglesias Gato, Diego, Elversang, J., Jørgensen, Flemming Steen, Kallunki, Tuula Anneli, Røder, Andreas, Brasso, K. & Moreira, José, 2022, In: Frontiers in Pharmacology. 13, 13 p., 869461.Research output: Contribution to journal › Journal article › Research › peer-review
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Molecular Profiling of Docetaxel-Resistant Prostate Cancer Cells Identifies Multiple Mechanisms of Therapeutic Resistance
Lima, T. S., Iglesias Gato, Diego, De Oliveira Souza, Luciano, Stenvang, Jan, Lima, D. S., Røder, Andreas, Brasso, K. & Moreira, José, 2021, In: Cancers. 13, 19 p.Research output: Contribution to journal › Journal article › Research
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Allosteric regulation of AMP-activated protein kinase by adenylate nucleotides and small-molecule drugs
Matos, A. L. D. S. A., Oakhill, J. S., Moreira, José, Loh, K., Galic, S. & Scott, J. W., 30 Apr 2019, In: Biochemical Society Transactions. 47, p. 733-741Research output: Contribution to journal › Review › Research › peer-review
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Pepticinnamins N, O, and P, Nonribosomal Peptides from the Soil-Derived Streptomyces mirabilis P8-A2
Mohamed, M. M. M., Abboud, M. M., Maleckis, M., De Oliveira Souza, Luciano, Moreira, José, Gotfredsen, C. H., Weber, T. & Ding, L., 2024, In: Journal of Natural Products. 87, 4, p. 1075–1083Research output: Contribution to journal › Journal article › Research › peer-review
ID: 37757167
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998
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Comparative analysis of evolutionarily conserved motifs of epidermal growth factor receptor 2 (HER2) predicts novel potential therapeutic epitopes
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
367
downloads
FABP7 and HMGCS2 are novel protein markers for apocrine differentiation categorizing apocrine carcinoma of the breast
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
230
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The stepwise evolution of the exome during acquisition of docetaxel resistance in breast cancer cells
Research output: Contribution to journal › Journal article › Research › peer-review
Published