José Moreira
Professor
Translational and Clinical Pharmacology
Jagtvej 160
2100 København Ø
A combined proteome and ultrastructural localization analysis of 14-3-3 proteins in transformed human amnion (AMA) cells
Shen, T., Ohlsson, G., Gromov, P., Gromova, I., Celis, J. E. & Moreira, José, 1 Jul 2008, In: Molecular and Cellular Proteomics. 7, 7, p. 1225-1240 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A single lysis solution for the analysis of tissue samples by different proteomic technologies
Gromov, P., Celis, J. E., Gromova, I., Rank, F., Timmermans, V. J. M. & Moreira, José, 2008, In: Molecular Oncology. 2, 4, p. 368-379 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A streamlined mass spectrometry-based proteomics workflow for large scale FFPE tissue analysis
Coscia, F., Doll, S., Bech, J. M., Schweizer, L., Mund, Andreas, Lengyel, E., Lindebjerg, J., Madsen, G. I., Moreira, José & Mann, Matthias, 2020, In: Journal of Pathology. 251, p. 110-112Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Acquisition of docetaxel resistance in breast cancer cells reveals upregulation of ABCB1 expression as a key mediator of resistance accompanied by discrete upregulation of other specific genes and pathways
Hansen, S. N., Westergaard, David, Thomsen, M. B. H., Vistesen, M. V., Do, K. N., Fogh, L., Belling, K. G., Wang, J., Yang, H., Gupta, R., Ditzel, H. J., Moreira, José, Brünner, N., Stenvang, Jan & Rasmussen, A. S., 2015, In: Tumor Biology. 36, 6, p. 4327-4338 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Allosteric regulation of AMP-activated protein kinase by adenylate nucleotides and small-molecule drugs
Matos, A. L. D. S. A., Oakhill, J. S., Moreira, José, Loh, K., Galic, S. & Scott, J. W., 30 Apr 2019, In: Biochemical Society Transactions. 47, p. 733-741Research output: Contribution to journal › Review › Research › peer-review
- Published
Apocrine cysts of the breast: Biomarkers, origin, enlargement, and relation with cancer phenotype
Celis, J. E., Gromov, P., Moreira, José, Cabezón, T., Friis, E., Vejborg, I. M. M., Proess, G., Rank, F. & Gromova, I., 1 Mar 2006, In: Molecular and Cellular Proteomics. 5, 3, p. 462-483 22 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Biomarker-guided repurposing of chemotherapeutic drugs for cancer therapy: a novel strategy in drug development
Stenvang, Jan, Kümler, I., Nygård, S. B., Smith, D. H., Nielsen, D., Brünner, N. & Moreira, José, 2013, In: Frontiers in Oncology. 3, 9 p., 313.Research output: Contribution to journal › Review › Research › peer-review
Bladder cancer-associated protein, a potential prognostic biomarker in human bladder cancer
Moreira, José, Ohlsson, G., Gromov, P., Simon, R., Sauter, G., Celis, J. E. & Gromova, I., 2010, In: Molecular & Cellular Proteomics. 9, 1, p. 161-77 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
CIP2A oncoprotein controls cell growth and autophagy through mTORC1 activation: CIP2A oncoprotein controls cell growth and autophagy through mTORC1 activation
Puustinen, P., Rytter, A., Mortensen, M., Kohonen, P., Moreira, José & Jäättelä, M., 2014, In: Journal of Cell Biology. 204, 5, p. 713-727 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Challenges and Opportunities in Oncoproteomics
Celis, J. E. & Moreira, José, 1 Jan 2010, In: Molecular Oncology. 4, 6, p. 459-460 2 p.Research output: Contribution to journal › Editorial › Research › peer-review
- Published
Characterization of breast precancerous lesions and myoepithelial hyperplasia in sclerosing adenosis with apocrine metaplasia
Celis, J. E., Gromova, I., Cabezón, T., Gromov, P., Shen, T., Timmermans, V. J. M., Rank, F. & Moreira, José, 2007, In: Molecular Oncology. 1, 1, p. 97-119 23 p.Research output: Contribution to journal › Journal article › Research
- Published
Chromatin-mediated transcriptional regulation by the yeast architectural factors NHP6A and NHP6B
Moreira, José & Holmberg, Steen, 2000, In: EMBO Journal. 19, 24, p. 6804-6813 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Clinical proteomics
Celis, J. E. & Moreira, José, 1 Oct 2008, In: Molecular and Cellular Proteomics. 7, 10, 1 p.Research output: Contribution to journal › Editorial › Research › peer-review
- Published
Co-expression of TIMP-1 and its cell surface binding partner CD63 in glioblastomas
Aaberg-Jessen, C., Sørensen, M. D., Matos, A. L. S. A., Moreira, José, Brünner, N., Møldrup Knudsen, A. & Kristensen, B. W., 9 Mar 2018, In: BMC Cancer. 18, 16 p., 270.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comparative analysis of evolutionarily conserved motifs of epidermal growth factor receptor 2 (HER2) predicts novel potential therapeutic epitopes
Deng, X., Zheng, X., Yang, H., Moreira, José, Brünner, N. & Christensen, Henrik, 2014, In: PLOS ONE. 9, 9, 9 p., e106448.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Contribution of Na+,HCO3--cotransport to cellular pH control in human breast cancer: a role for the breast cancer susceptibility locus NBCn1 (SLC4A7)
Bødtkjer, E., Moreira, José, Mele, M., Vahl, P., Wielenga, V. T., Christiansen, P. M., Jensen, V. E. D., Pedersen, Stine Helene Falsig & Aalkjær, C., 2013, In: International Journal of Cancer. 132, 6, p. 1288-1299 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Datin, a yeast poly(dA:dT)-binding protein, behaves as an activator of the wild-type ILV1 promoter and interacts synergistically with Reb1p
Moreira, José, Remacle, J. E., Kielland-Brandt, M. & Holmberg, Steen, 1998, In: Molecular and General Genetics. 258, 1-2, p. 95-103 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Determination of Antibody Specificity by Western Blotting
Celis, J. E., Moreira, José & Gromov, P., 1 Dec 2006, Cell Biology, Four-Volume Set. Elsevier Science Inc., Vol. 1. p. 527-532 6 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Down-regulation of the tumor suppressor protein 14-3-3σ is a sporadic event in cancer of the breast
Moreira, José, Ohlsson, G., Rank, F. E. & Celis, J. E., 1 Apr 2005, In: Molecular and Cellular Proteomics. 4, 4, p. 555-569 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Drug transporters in breast cancer: response to anthracyclines and taxanes
Kümler, I., Stenvang, Jan, Moreira, José, Brünner, N. & Nielsen, Dorte Lisbet, Sep 2015, In: Expert Review of Anticancer Therapy. 15, 9, p. 1075-1092 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Elucidation of Altered Pathways in Tumor-Initiating Cells of Triple-Negative Breast Cancer: A Useful Cell Model System for Drug Screening
Christensen, A. G., Ehmsen, S., Terp, M. G., Batra, R., Alcaraz, N., Baumbach, J., Noer, Julie Boertmann, Moreira, José, Leth-Larsen, R., Larsen, M. R. & Ditzel, H. J., 2017, In: Stem Cells. 35, 8, p. 1898-1912Research output: Contribution to journal › Journal article › Research › peer-review
ErbB2-driven breast cancer cell invasion depends on a complex signaling network activating myeloid zinc finger-1-dependent cathepsin B expression
Rafn, B., Nielsen, C. F., Andersen, S. H., Szyniarowski, P., Corcelle-Termeau, E., Valo, E., Fehrenbacher, N., Olsen, C. J., Daugaard, M., Egebjerg, C., Bøttzauw, T., Kohonen, P., Nylandsted, J., Hautaniemi, S., Moreira, José, Jaattela, M. & Kallunki, T., 2012, In: Molecular Cell. 45, 6, p. 764-776 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Establishment and characterization of models of chemotherapy resistance in colorectal cancer: towards a predictive signature of chemoresistance
Jensen, N. F., Stenvang, J., Beck, M. K., Hanáková, B., Belling, K. C., Do, K. N., Viuff, B. M., Nygård, S. B., Gupta, R., Rasmussen, M. H., Tarpgaard, L. S., Hansen, T. P., Budinská, E., Pfeiffer, P., Bosman, F., Tejpar, S., Roth, A., Delorenzi, M., Andersen, C. L., Rømer, M. U. K. & 2 others, , 24 Feb 2015, In: Molecular Oncology. 9, 6, p. 1169-1185 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
Expression of the tumor suppressor protein 14-3-3 sigma is down-regulated in invasive transitional cell carcinomas of the urinary bladder undergoing epithelial-to-mesenchymal transition
Moreira, José, Gromov, P. & Celis, J. E., 2004, In: Molecular and Cellular Proteomics. 3, 4, p. 410-9 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
FABP7 and HMGCS2 are novel protein markers for apocrine differentiation categorizing apocrine carcinoma of the breast
Gromov, P., Espinoza, J. A., Talman, M., Honma, N., Kroman, N., Wielenga, V. T., Moreira, José & Gromova, I., 2014, In: P L o S One. 9, 11, 14 p., e112024.Research output: Contribution to journal › Journal article › Research › peer-review
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Functional proteomic profiling of triple-negative breast cancer
Gromova, I., Espinoza, J. A., Grauslund, M., Santoni Rugiu, Eric, Talman, M. L. M., van Oostrum, J. & Moreira, José, 2021, In: Cells. 10, 10, 14 p., 2768.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gel-Based Proteomics of Clinical Samples Identifies Potential Serological Biomarkers for Early Detection of Colorectal Cancer
Thorsen, S. F., Gromova, I., Christensen, I. J., Fredriksson, S., Andersen, C. L., Nielsen, H. J., Stenvang, Jan & Moreira, José, Dec 2019, In: International Journal of Molecular Sciences (Online). 20, 19 p., 6082.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
HLA Class II Histocompatibility Antigen gamma Chain (CD74) Expression Is Associated with Immune Cell Infiltration and Favorable Outcome in Breast Cancer
Noer, Julie Boertmann, Talman, M. M. & Moreira, José, 2021, In: Cancers. 13, 24, 16 p., 6179.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High level PHGDH expression in breast is predominantly associated with keratin 5-positive cell lineage independently of malignancy
Gromova, I., Gromov, P., Honma, N., Kumar, S., Rimm, D., Talman, M. M., Wielenga, V. T. & Moreira, José, 2015, In: Molecular Oncology. 9, 8, p. 1636-1654 19 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Human mammary fibroblasts stimulate invasion of breast cancer cells in a three-dimensional culture and increase stroma development in mouse xenografts.
Olsen, C. J., Moreira, José, Lukanidin, E. M. & Ambartsumian, N. S., 1 Jan 2010, In: BMC Cancer. 10, 1 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification and characterization of a new TIMP-1 binding protein
Moreira, José, Høeberg, M., Lademann, U. A., Viuff, B. M., Jensen, L. V., Stenvang, Jan, Nygård, S. B., Ørum-Madsen, M. S., Vistesen, M. V., Fuglsang, Anja Thoe, Liu, S. & Brünner, N., 2015, In: Cancer Research. 75, 9 suppl., 1 p., Abstract P5-07-08.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Identification of BLCAP as a novel STAT3 interaction partner in bladder cancer
Gromova, I., Svensson, S., Gromov, P. & Moreira, José, 2017, In: PloS one. 12, 11, 18 p., e0188827.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of a subset of breast carcinomas characterized by expression of cytokeratin 15: Relationship between CK15+ progenitor/amplified cells and pre-malignant lesions and invasive disease
Celis, J. E., Gromova, I., Cabezón, T., Gromov, P., Shen, T., Timmermans-Wielenga, V., Rank, F. & Moreira, José, 1 Jan 2007, In: Molecular Oncology. 1, 3, p. 321-349 29 p.Research output: Contribution to journal › Journal article › Research › peer-review
Identification of extracellular and intracellular signaling components of the mammary adipose tissue and its interstitial fluid in high risk breast cancer patients: Toward dissecting the molecular circuitry of epithelial-adipocyte stromal cell interactions
Celis, J. E., Cabezón, T., Gromov, P., Friis, E., Rank, F., Gromova, I. & Moreira, José, 1 Apr 2005, In: Molecular and Cellular Proteomics. 4, 4, p. 492-522 31 p.Research output: Contribution to journal › Journal article › Research
- Published
Immunoexpression analysis and prognostic value of BLCAP in breast cancer
Gromova, I., Gromov, P., Kroman, N., Wielenga, V. T., Simon, R., Sauter, G. & Moreira, José, 2012, In: P L o S One. 7, 9, 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of proteomics on bladder cancer research
Celis, J. E., Gromova, I., Moreira, José, Cabezon, T. & Gromov, P., 2004, In: Pharmacogenomics. 5, 4, p. 381-94 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Intact and cleaved plasma soluble urokinase receptor in patients with metastatic colorectal cancer treated with oxaliplatin with or without cetuximab
Tarpgaard, L. S., Christensen, I. J., Høyer-Hansen, G., Lund, I. K., Guren, T. K., Glimelius, B., Sorbye, H., Tveit, K. M., Nielsen, H. J., Moreira, José, Pfeiffer, P. & Brünner, N., 15 Nov 2015, In: International Journal of Cancer. 137, 10, p. 2470-7 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Integrating proteomic and functional genomic technologies in discovery-driven translational breast cancer research
Celis, J. E., Gromov, P., Gromova, I., Moreira, J. M. A., Cabezón, T., Ambartsumian, N., Grigorian, M., Lukanidin, E., Thor Straten, P., Guldberg, P., Bartkova, J., Bartek, J., Lukas, J., Lukas, C., Lykkesfeldt, A., Jäättelä, M., Roepstorff, P., Bolund, L., Ørntoft, T. F., Brünner, N. & 5 others, , 2003, In: Molecular and Cellular Proteomics. 2, 6, p. 369-377 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Interactions of ion transporters and channels with cancer cell metabolism and the tumour microenvironment
Andersen, Anne Poder, Moreira, José & Pedersen, Stine Helene Falsig, 2014, In: Philosophical Transactions of the Royal Society B: Biological Sciences. 369, 1638, 11 p., 20130098.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Itraconazole Reverts ABCB1-Mediated Docetaxel Resistance in Prostate Cancer
Lima, T. S., De Oliveira Souza, Luciano, Iglesias Gato, Diego, Elversang, J., Jørgensen, Flemming Steen, Kallunki, Tuula Anneli, Røder, Andreas, Brasso, K. & Moreira, José, 2022, In: Frontiers in Pharmacology. 13, 13 p., 869461.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Let-7 microRNA controls invasion-promoting lysosomal changes via the oncogenic transcription factor myeloid zinc finger-1
Tvingsholm, S. A., Hansen, M. B., Clemmensen, K. K. B., Brix, D. M., Rafn, B., Frankel, Lisa, Louhimo, R., Moreira, José, Hautaniemi, S., Gromova, I., Jäättelä, M. & Kallunki, Tuula Anneli, 2018, In: Oncogene. 7, 2, p. 1-15 15 p., 14.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Looking back, to go forward
Moreira, José, 1 Jan 2014, In: Molecular Oncology. 8, 3, p. 445-446 2 p.Research output: Contribution to journal › Editorial › Research › peer-review
Loss of expression of the adipocyte-type fatty acid-binding protein (A-FABP) is associated with progression of human urothelial carcinomas
Ohlsson, G., Gromov, P., Sauter, G., Celis, J. E. & Moreira, José, 2005, In: Molecular and Cellular Proteomics. 4, 4, p. 570-581 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Metallopeptidase Inhibitor 1 (TIMP-1) promotes receptor tyrosine kinase c-Kit signaling in colorectal cancer
Nordgaard, C., Doll, S., Matos, A. L. D. S. A., Høeberg, M., Kazi, J. U., Friis, S., Stenvang, Jan, Rönnstrand, L., Mann, Matthias & Moreira, José, 2019, In: Molecular Oncology. 13, 12, p. 2646-2662Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular Oncology journal has moved to open access
Celis, J. E. & Moreira, José, 1 Feb 2017, In: Molecular Oncology. 11, 2, 1 p.Research output: Contribution to journal › Editorial › Research › peer-review
- Published
Molecular Profiling of Docetaxel-Resistant Prostate Cancer Cells Identifies Multiple Mechanisms of Therapeutic Resistance
Lima, T. S., Iglesias Gato, Diego, De Oliveira Souza, Luciano, Stenvang, Jan, Lima, D. S., Røder, Andreas, Brasso, K. & Moreira, José, 2021, In: Cancers. 13, 19 p.Research output: Contribution to journal › Journal article › Research
- Published
Molecular characterization of apocrine carcinoma of the breast: validation of an apocrine protein signature in a well-defined cohort
Celis, J. E., Cabezon, T., Moreira, José, Gromov, P., Gromova, I., Timmermans-Wielenga, V., Iwase, T., Akiyama, F., Honma, N. & Rank, F., 2009, In: Molecular Oncology. 3, 3, p. 220-37Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular characterization of irinotecan (SN-38) resistant human breast cancer cell lines
Jandu, H., Aluzaité, K., Fogh, L., Thrane, S. W., Noer, J. B., Proszek, J., Nguyen Do, K., Hansen, S. N., Damsgaard-Hansen, B., Nielsen, S. L., Stougaard, M., Knudsen, B. R., Moreira, J., Hamerlik, P., Gajjar, M., Smid, M., Martens, J., Foekens, J., Pommier, Y., Brünner, N. & 2 others, , 22 Jan 2016, In: B M C Cancer. 16, 13 p., 34.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular pathology of breast apocrine carcinomas: A protein expression signature specific for benign apocrine metaplasia
Celis, J. E., Gromova, I., Gromov, P., Cabezón, T., Friis, E., Rank, F. & Moreira, José, 2006, In: FEBS Letters. 580, 12, p. 2935-2944 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Neither Reb1p nor poly(dA*T) elements are responsible for the highly specific chromatin organization at the ILV1 promoter
Moreira, José, Hörz, W. & Holmberg, Steen, 2001, In: Journal of Biological Chemistry. 277, 5, p. 3202-9 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 37757167
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Comparative analysis of evolutionarily conserved motifs of epidermal growth factor receptor 2 (HER2) predicts novel potential therapeutic epitopes
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
367
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FABP7 and HMGCS2 are novel protein markers for apocrine differentiation categorizing apocrine carcinoma of the breast
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
230
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The stepwise evolution of the exome during acquisition of docetaxel resistance in breast cancer cells
Research output: Contribution to journal › Journal article › Research › peer-review
Published