Is it possible to revert lipid changes associated with Parkinson’s Disease?

The title of the project is "Reverting brain lipid changes associated with Parkinson’s Disease pathology in patients’ neuronal cells". 
Parkinson’s Disease is a neurodegenerative disorder characterised by the deposition of protein clumps in the brain of patients as well as the loss of specific neurons that are important for reward and movement. The human brain is the second richest organ in lipid, or fat, molecules and their levels are tightly regulated by our body under healthy conditions. However, it is now well established that the levels of specific lipids are increased in Parkinson’s Disease patients’ brains. 

Céline Galvagnion describes her project further: 

“My research aims at testing novel strategies to revert lipid changes associated with Parkinson’s Disease and decrease protein clumps in neuronal cells. First, I will screen different approaches to modulate the activity of proteins involved in lipid synthesis and/or processing to model lipid changes in the opposite direction to those observed in Parkinson’s Disease patients. Then, I will test successful treatments in patients’ neuronal cells as potential therapeutics capable to both revert Parkinson’s Disease-related lipid changes and prevent pathological protein clumping." 

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