Synthesis of oligonucleotide phosphorodithioates

Research output: Contribution to journalJournal articleResearchpeer-review

  • G. Beaton
  • W. K D Brill
  • A. Grandas
  • Y. X. Ma
  • J. Nielsen
  • E. Yau
  • M. H. Caruthers
  • John Nielsen

The synthesis of DNA containing sulfur at the two nonbonding internucleotide valencies is reported. Several different routes using either tervalent or pentavalent mononucleotide synthons are described.

Original languageEnglish
JournalTetrahedron
Volume47
Issue number14-15
Pages (from-to)2377-2388
Number of pages12
ISSN0040-4020
DOIs
Publication statusPublished - 1 Jan 1991

ID: 131116150