Structural Biology

Structural Biology Section: Unlocking the secrets of proteins for next-generation drugs.

The Structural Biology Section within the Department of Drug Design and Pharmacology is a core unit dedicated to deciphering the 3D structures of biomolecules, particularly those with potential as drug targets. Our team utilizes a comprehensive toolbox that includes cutting-edge techniques like X-ray crystallography, cryo-electron microscopy, small angle X-ray scattering (SAXS), and computational chemistry.

By integrating these methods, we unlock the intricate details of these molecules at various scales, from atomic-level resolution to overall protein assemblies. This comprehensive approach provides crucial insights for the design and development of novel therapeutics.

Furthermore, we leverage computational chemistry to analyze and model these structures. This allows for in-silico simulations and predictions of drug-target interactions, accelerating the discovery and optimization of potential drug candidates.

This collaborative approach bridges the gap between fundamental research and drug discovery, ultimately aiming to accelerate the creation of new medications.

Research Groups