Alexander Sebastian Hauser
Associate Professor
Pharmaceutical Informatics
Universitetsparken 2
2100 København Ø
- 2014
- Published
Investigations and design of pyridine-2-carboxylic acid thiazol-2-ylamide analogs as methionine aminopeptidase inhibitors using 3D-QSAR and molecular docking
Hauser, Alexander Sebastian, 1 Aug 2014, In: Medicinal Chemistry Research. 23, 8, p. 3861 3875 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2015
- Published
A new crystal structure fragment-based pharmacophore method for G protein-coupled receptors
Fidom, K., Isberg, V., Hauser, Alexander Sebastian, Mordalski, S., Lehto, T., Bojarski, A. J. & Gloriam, David E., Jan 2015, In: Methods. 71, p. 104-112 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2016
- Published
LEADS-PEP: A Benchmark Data Set for Assessment of Peptide Docking Performance
Hauser, Alexander Sebastian & Windshügel, B., 2016, In: Journal of Chemical Information and Modeling.Research output: Contribution to journal › Journal article › Research › peer-review
LEADS-PEP: A Benchmark Data Set for Assessment of Peptide Docking Performance
Hauser, Alexander Sebastian & Windshügel, B., 11 Jan 2016, In: Journal of Chemical Information and Modeling. 56, 1, p. 188-200 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GPCRdb: an information system for G protein-coupled receptors
Isberg, V., Mordalski, S., Munk, C., Rataj, K., Harpsøe, Kasper, Hauser, Alexander Sebastian, Vroling, B., Bojarski, A. J., Vriend, G. & Gloriam, David E., 4 Jan 2016, In: Nucleic Acids Research. 44, D1, p. D356-64Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GPCRdb: The G protein-coupled receptor database - an introduction
Munk, C., Isberg, V., Mordalski, S., Harpsøe, Kasper, Rataj, K., Hauser, Alexander Sebastian, Kolb, P., Bojarski, A. J., Vriend, G. & Gloriam, David E., Jul 2016, In: British Journal of Pharmacology. 173, 14, p. 2195-207 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Integrating structural and mutagenesis data to elucidate GPCR ligand binding
Munk, C., Harpsøe, Kasper, Hauser, Alexander Sebastian, Isberg, V. & Gloriam, David E., Oct 2016, In: Current Opinion in Pharmacology. 30, p. 51-58 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2017
- Published
Selectivity determinants of GPCR-G-protein binding
Flock, T., Hauser, Alexander Sebastian, Lund, N., Gloriam, David E., Balaji, S. & Babu, M. M., 18 May 2017, In: Nature. 545, 7654, p. 317-322 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of Histamine H3 Receptor Ligands Using a New Crystal Structure Fragment-based Method
Frandsen, I. O., Boesgaard, M. W., Fidom, K., Hauser, Alexander Sebastian, Isberg, V., Bräuner, Hans, Wellendorph, Petrine & Gloriam, David E., 6 Jul 2017, In: Scientific Reports. 7, 1, 10 p., 4829.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Trends in GPCR drug discovery: new agents, targets and indications
Hauser, Alexander Sebastian, Gloriam, David E., Attwood, M. M., Rask-Andersen, M. & Schiöth, H. B., 27 Oct 2017, In: Nature Reviews. Drug Discovery. 16, p. 829-842 14 p., 178.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 143688078
Most downloads
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561
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Pharmacogenomics of GPCR Drug Targets
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
432
downloads
The orphan G protein-coupled receptor GPR139 is activated by the peptides: Adrenocorticotropic hormone (ACTH), α-, and β-melanocyte stimulating hormone (α-MSH, and β-MSH), and the conserved core motif HFRW
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
318
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GPCRdb: an information system for G protein-coupled receptors
Research output: Contribution to journal › Journal article › Research › peer-review
Published