Christian Adam Olsen

Christian Adam Olsen

Professor

ORCID: 0000-0002-2953-8942

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  1. Published

    New Linker Strategies in SPS of Neuroactive Wasp Toxin Analogues

    Olsen, Christian Adam, Jaroszewski, J. W. & Franzyk, Henrik, 2005.

    Research output: Contribution to conference › Poster › Research

  2. Published

    Expansion of the Lysine Acylation Landscape

    Olsen, Christian Adam, 2012, In: Angewandte Chemie International Edition. 51, 16, p. 3755-3756

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Solid-phase synthesis of neuroactive spider-wasp hybrid toxin analogues using a backbone amide linker

    Olsen, Christian Adam, Witt, M., Franzyk, Henrik & Jaroszewski, J. W., 2007, In: Tetrahedron Letters. 48, 3, p. 405-408

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Nanomolær inhibering med hvepsetoksinanaloger – syntese og elektrofysiologi

    Olsen, Christian Adam, Franzyk, Henrik & Jaroszewski, J. W., 2006, In: Dansk Kemi. 87, p. 23-26 4 p.

    Research output: Contribution to journal › Journal article › Communication

  5. Published

    Kunstige forsvarspeptider

    Olsen, Christian Adam, Franzyk, Henrik & Jaroszewski, J. W., 2006, In: Lægemiddelforskning. p. 18-19 2 p.

    Research output: Contribution to journal › Journal article › Communication

  6. Published

    Fukuyama-Mitsunobu Alkylation in Amine Synthesis on Solid Phase Revisited: N-Alkylation with Secondary Alcohols and Synthesis of Curtatoxins

    Olsen, Christian Adam, Witt, M., Hansen, S. H., Jaroszewski, J. W. & Franzyk, Henrik, 2005, In: Tetrahedron. 61, p. 6046-6055 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Aziridines in parallel- and solid-phase synthesis

    Olsen, Christian Adam, Bonke, G., Vedel, L., Franzyk, Henrik & Jaroszewski, J. W., 2007, In: European Journal of Organic Chemistry. 2007, 11, p. 1717-1724

    Research output: Contribution to journal › Review › Research › peer-review

  8. Published

    Hurtige genveje til nye lægemidler

    Olsen, Christian Adam, Franzyk, Henrik & Jaroszewski, J. W., 2003, In: Lægemiddelforskning. 2003, p. 8-9 2 p.

    Research output: Contribution to journal › Journal article › Communication

  9. Published

    Solid-phase peptide synthesis and circular dichroism study of chiral ß-peptoid homooligomers

    Olsen, Christian Adam, Lambert, M., Witt, M., Franzyk, Henrik & Jaroszewski, J. W., 2008, In: Amino Acids. 34, 3, p. 465-471

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    α-Peptide/ß-Peptoid Chimeras

    Olsen, Christian Adam, Bonke, G., Vedel, L., Adsersen, A., Witt, M., Franzyk, Henrik & Jaroszewski, J. W., 2007, In: Organic Letters. 9, 8, p. 1549–1552 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Diols as Building Blocks in Solid-Phase Synthesis of Polyamine Toxins by Fukuyama-Mitsunobu Alkylation

    Olsen, Christian Adam, Witt, M., Jaroszewski, J. W. & Franzyk, Henrik, 2004, In: Synlett : Accounts and Rapid Communications in Synthetic Organic Chemistry. p. 473-476 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    The Choice of Phosphane Reagent in Fukuyama-Mitsunobu Alkylation: Intramolecular Selectivity Between Primary and Secondary Alcohols in the Preparation of Asymmetric Tetraamine Building Blocks for Synthesis of Philanthotoxins

    Olsen, Christian Adam, Jørgensen, M. R., Witt, M., Mellor, I. R., Usherwood, P. N. R., Jaroszewski, J. W. & Franzyk, Henrik, 2003, In: European Journal of Organic Chemistry. p. 3288-3299 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Peptoid-Peptide hybrid backbone architectures

    Olsen, Christian Adam, 25 Jan 2010, In: ChemBioChem. 11, 2, p. 152-160

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Profiling of Substrates for Zinc-dependent Lysine Deacylase Enzymes: HDAC3 Exhibits Decrotonylase Activity In Vitro

    Olsen, Christian Adam & Madsen, A., 2012, In: Angewandte Chemie International Edition. 51, 36, p. 9083-9087

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    N-Alkylation Reactions and Indirect Formation of Amino Functionalities in Solid-Phase Synthesis

    Olsen, Christian Adam, Jaroszewski, J. W. & Franzyk, Henrik, 2005, In: Synthesis. p. 2631-2653 23 p.

    Research output: Contribution to journal › Review › Research › peer-review

  16. Published

    Selectively N-protected enantiopure 2,5-disubstituted piperazines: Avoiding the pitfalls in solid-phase Fukuyama-Mitsunobu cyclizations

    Ottesen, L. K., Olsen, Christian Adam, Witt, M., Jaroszewski, J. W. & Franzyk, Henrik, 2009, In: Chemistry: A European Journal. 15, 12, p. 2966-2978

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Effect of co-inhabiting coagulase negative staphylococci on S. Aureus agr quorum sensing, host factor binding, and biofilm formation

    Peng, P., Baldry, M., Gless, B. H., Bojer, Martin Saxtorph, Espinosa-Gongora, C., Baig, S. J., Andersen, P. S., Olsen, Christian Adam & Ingmer, Hanne, 2019, In: Frontiers in Microbiology. 10, SEP, 14 p., 2212.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Modular total synthesis of lamellarin D

    Pla, D., Marchal, A., Olsen, Christian Adam, Albericio, F. & Álvarez, M., 20 Sep 2005, In: Journal of Organic Chemistry. 70, 20, p. 8231-8234 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Synthesis and structure-activity relationship study of potent cytotoxic analogues of the marine alkaloid lamellarin D

    Pla, D., Marchal, A., Olsen, Christian Adam, Francesch, A., Cuevas, C., Albericio, F. & Alvarez, M., 1 Jun 2006, In: Journal of Medicinal Chemistry. 49, 11, p. 3257-3268 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Mechanism-based Inhibitors of the Human Sirtuin 5 Deacylase: Structure-Activity Relationship, Biostructural, and Kinetic Insight

    Rajabi, N., Auth, M., Troelsen, K. R., Pannek, M., Bhatt, D., Fontenas, M., Hirschey, M., Steegborn, C., Madsen, A. S. & Olsen, Christian Adam, 20 Nov 2017, In: Angewandte Chemie, Int. Ed.. 56, 47, p. 14836-14841

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Targeting Sirtuins: Substrate Specificity and Inhibitor Design

    Rajabi, N., Galleano, I., Madsen, A. S. & Olsen, Christian Adam, 3 Feb 2018, Progress in Molecular Biology and Translational Science: Sirtuins in Health and Disease. Elsevier, p. 25-69 (Progress in Molecular Biology and Translational Science, Vol. 154).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  22. Published

    Investigation of Carboxylic Acid Isosteres and Prodrugs for Inhibition of the Human SIRT5 Lysine Deacylase Enzyme**

    Rajabi, N., Hansen, T. N., Nielsen, A. L., Nguyen, H. T., Bæk, M., Bolding, J. E., Bahlke, O., Petersen, S. E. G., Bartling, Christian Reinhard Otto, Strømgaard, Kristian & Olsen, Christian Adam, 2022, In: Angewandte Chemie - International Edition. 61, 22, 9 p., e202115805.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Dethioacylation by sirtuins 1–3: Considerations for drug design using mechanism-based sirtuin inhibition

    Rajabi, N., Nielsen, A. L. & Olsen, Christian Adam, 2020, In: A C S Medicinal Chemistry Letters. 11, 10, p. 1886-1892

    Research output: Contribution to journal › Letter › Research › peer-review

  24. Published

    A Robust Proton Flux (pHlux) Assay for Studying the Function and Inhibition of the Influenza A M2 Proton Channel

    Santner, P., Martins, J. M. D. S., Laursen, J. S., Behrendt, L., Riber, Leise, Olsen, Christian Adam, Arkin, I. T., Winther, Jakob R., Willemoës, Martin & Lindorff-Larsen, Kresten, 2018, In: Biochemistry. 57, 41, p. 5949-5956

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Random mutagenesis analysis of the Influenza A M2 proton channel reveals novel resistance mutants

    Santner, P., Martins, J. M. D. S., Kampmeyer, Caroline, Hartmann-Petersen, Rasmus, Laursen, J. S., Stein, Amelie, Olsen, Christian Adam, Arkin, I. T., Winther, Jakob R., Willemoës, Martin & Lindorff-Larsen, Kresten, 2018, In: Biochemistry. 57, 41, p. 5957-5968

    Research output: Contribution to journal › Journal article › Research › peer-review

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