Dan Stærk
Head of Department, Visiting professor
Administration and Operations
Jagtvej 160
2100 København Ø
Biopharmaceuticals
Jagtvej 162
2100 København Ø
- Published
Comparative study of the drug delivery mechanism of L-penetratin and D-penetratin
Birch, D., Christensen, M. V., Stærk, Dan, Franzyk, Henrik & Nielsen, Hanne Mørck, 2018.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
- Published
Comprehensive analysis of commercial willow bark extracts by new technology platform: combined use of metabolomics, high-perfomance liquid chromatography-solid-phase extraction-nuclear magnetic resonance spectroscopy and high-resolution radical scavenging assay
Agnolet, S., Wiese, S., Verpoorte, R. & Stærk, Dan, 2012, In: Journal of Chromatography A. 1262, p. 130-137 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Conformational studies of indole alkaloids corynantheine and dihydrocorynantheine by dynamic 1H NMR spectroscopy and computational methods: steric effects of ethyl vs. vinyl group
Stærk, Dan, Norrby, P. & Jaroszewski, J. W., 2001, In: Journal of Organic Chemistry. 66, p. 2217-2221Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Coupling HPLC-SPE-NMR with a microplate-based high-resolution antioxidant assay for efficient analysis of antioxidants in food – Validation and proof-of-concept study with caper buds
Wiese, S., Wubshet, S. G., Nielsen, J. & Stærk, Dan, 2013, In: Food Chemistry. 141, 4, p. 4010-4018Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Coupling microplate-based antibacterial assay with liquid chromatography for high-resolution growth inhibition profiling of crude extracts: Validation and proof-of-concept study with Staphylococcus aureus
Ardalani, H., Anam, S., Kromphardt, K. J. K., Stærk, Dan & Kongstad, Kenneth Thermann, 2021, In: Molecules. 26, 6, 12 p., 1550.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Coupling of a high-resolution monoamine oxidase-A inhibitor assay and HPLC-SPE-NMR for advanced bioactivity-profiling of plant extracts
Grosso, C., Jäger, A. & Stærk, Dan, 2013, In: Phytochemical Analysis. 24, 2, p. 141-147Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cytotoxic activity of some phenanthroindolizidine N-Oxide alkaloids from Cynanchum vincetoxicum
Stærk, Dan, Christensen, J., Lemmich, E., Duus, J. Ø., Olsen, C. E. & Jaroszewski, J. W., 2000, In: Journal of Natural Products. 63, 11, p. 1584-1586Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Data-dependent acquisition-mass spectrometry guided isolation of new benzoxazinoids from the roots of Acanthus mollis L.
Bhattarai, B., Steffensen, S. K., Stærk, Dan, Laursen, B. B. & Fomsgaard, I. S., 2022, In: International Journal of Mass Spectrometry. 474, 10 p., 116815.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Detection of Seasonal Variation in Aloe Polysaccharides Using Carbohydrate Detecting Microarrays
Isager Ahl, Louise, Al-Husseini, N., Al-Helle, S., Stærk, Dan, Grace, O. M., Willats, W. G. T., Mravec, Jozef, Jørgensen, Bodil & Rønsted, Nina, 2019, In: Frontiers in Plant Science. 10, p. 1-14 512.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Development of a bioassay-coupled HPLC-SPE-ttNMR platform for identification of α-glucosidase inhibitors in apple peel (Malus × domestica Borkh.)
Schmidt, J. S., Lauridsen, M. B., Dragsted, Lars Ove, Nielsen, J. & Stærk, Dan, 2012, In: Food Chemistry. 135, 3, p. 1692-1699 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Discovering new natural products directly from crude extracts by HPLC-SPE-NMR: chinane diterpenes in Harpagophytum procumbens
Clarkson, C., Stærk, Dan, Hansen, S. H., Smith, P. J. & Jaroszewski, J. W., 2006, In: Journal of Natural Products. 69, p. 527-530Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dovyalicin-type spermidine alkaloids from Dovyalis species
Rasmussen, B., Nkurunziza, A., Witt, M., Oketch-Rabah, H. A., Jaroszewski, J. W. & Stærk, Dan, 2006, In: Journal of Natural Products. 69, p. 1300-1304Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dual High-Resolution α-Glucosidase and Radical Scavenging Profiling Combined with HPLC-HRMS-SPE-NMR for Identification of Minor and Major Constituents Directly from the Crude Extract of Pueraria lobata
Liu, B., Kongstad, Kenneth Thermann, Qinglei, S., Nyberg, N., Jäger, A. & Stærk, Dan, 13 Feb 2015, In: Journal of Natural Products. 78, 2, p. 294–300 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dual high-resolution inhibition profiling and HPLC-HRMS-SPE-NMR analysis for identification of α-glucosidase and radical scavenging inhibitors in Solanum americanum Mill.
Silva, E. L. E., Almeida-Lafetá, R. C., Borges, R. M. & Stærk, Dan, 2017, In: Fitoterapia. 118, p. 42-48Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dual high-resolution α-glucosidase and PTP1B profiling combined with HPLC-PDA-HRMS-SPE-NMR analysis for the identification of potentially antidiabetic chromene meroterpenoids in Rhododendron capitatum
Liang, Chao, Kjaerulff, Louise, Hansen, Paul Robert, Kongstad, Kenneth Thermann & Stærk, Dan, 2021, In: Journal of Natural Products. 84, p. 2454-2467Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Edible seaweed as future functional food: Identification of α-glucosidase inhibitors by combined use of high-resolution α-glucosidase inhibition profiling and HPLC-HRMS-SPE-NMR
Liu, B., Kongstad, Kenneth Thermann, Wiese, S., Jäger, A. K. & Stærk, Dan, 2016, In: Food Chemistry. 203, p. 16-22 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of residual water and microwave heating on half-lifes of reagents and reactive intermediates in peptide synthesis
Shelton, A. P. T., Pedersen, S. L., Stærk, Dan & Jensen, Knud Jørgen, 2012, In: Chemistry: A European Journal. 18, 29, p. 9024-9031 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Efficient and versatile COMU-mediated solid-phase submonomer synthesis of arylopeptoids (oligomeric N-substituted aminomethyl benzamides)
Hjelmgaard, T., Faure, S., Stærk, Dan, Taillefumier, C. & Nielsen, J., 2011, In: Organic & Biomolecular Chemistry. 9, p. 6832-6843 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Eremane, viscidane and isozizaene diterpenoids from the leaves of Eremophila rigida and their absolute configurations
Liang, Chao, Ndi, C., Semple, S., Buirchell, B., Coriani, S., Møller, Birger Lindberg & Stærk, Dan, 2024, In: Phytochemistry. 219, 16 p., 113972.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Erratum: "Naravelia zeylanica: Occurrence of primary benzamides in flowering plants" (Natural Product Research vol. 19 (3) (291-294))
Jaroszewski, J. W., Stærk, Dan, Holm-Møller, S. B., Jensen, T. H., Franzyk, Henrik & Somanadhan, B., 1 Jun 2005, In: Natural Product Research. 19, 4, 1 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Erythrocyte membrane modifying agents and the inhibition of Plasmodium falciparum growth: structure-activity relationships for betulinic acid analogues
Ziegler, H. L., Franzyk, Henrik, Sairafianpour, M., Tabatabai, M., Tehrani, M. D., Bagherzadeh, K., Hägerstrand, H., Stærk, Dan & Jaroszewski, J. W., 2004, In: Bioorganic & Medicinal Chemistry. 12, p. 119-127Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evaluation of the antidiabetic potential of Psidium guajava L. (Myrtaceae) using assays for α-glucosidase, α-amylase, muscle glucose uptake, liver glucose production and triglyceride accumulation in adipocytes
Beidokhti, M. N., Eid, H. M., Villavicencio, M. L. S., Jäger, A. K., Lobbens, E. S., Rasoanaivo, P. R., McNair, Laura M., Haddad, P. S. & Stærk, Dan, 17 Apr 2020, In: Journal of Ethnopharmacology. 257, 8 p., 112877.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Expanding the landscape of diterpene structural diversity by stereochemically controlled combinatorial biosynthesis
Andersen-Ranberg, Johan, Kongstad, Kenneth Thermann, Nielsen, M. T., Bjerg Jensen, N., Pateraki, Irini, Bach, S. S., Hamberger, B., Zerbe, P., Stærk, Dan, Bohlmann, J., Møller, Birger Lindberg & Hamberger, B. R., 2016, In: Angewandte Chemie International Edition. 55, 6, p. 2142-2146 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Expanding the terpene biosynthetic code with non-canonical 16 carbon atom building blocks
Ignea, C., Raadam, Morten Hessellund, Koutsaviti, A., Zhao, Yong, Duan, Yaotao, Harizani, M., Miettinen, Karel, Georgantea, P., Rosenfeldt, M., Viejo-Ledesma, S. E., Petersen, Mikael Agerlin, Bredie, Wender, Stærk, Dan, Roussis, V., Ioannou, E. & Kampranis, Sotirios, 2022, In: Nature Communications. 13, 16 p., 5188.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Expedient solution-phase synthesis and NMR studies of arylopeptoids
Hjelmgaard, T., Faure, S., Stærk, Dan, Taillefumier, C. & Nielsen, J., 2011, In: European Journal of Organic Chemistry. 2011, 22, p. 4121-4132 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Facilitated visual interpretation of scores in principal component analysis by bioactivity-labeling of 1H NMR spectra - metabolomics investigation and identification of a new α-glucosidase inhibitor in Radix Astragali
Liu, Y., Nyberg, N., Jäger, A. K. & Stærk, Dan, 2017, In: Molecules. 22, 3, 12 p., 411.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Fluorophore labeling of a cell-penetrating peptide induces differential effects on its cellular distribution and affects cell viability
Birch, D., Christensen, M. V., Stærk, Dan, Franzyk, Henrik & Nielsen, Hanne Mørck, 2017, In: B B A - Biomembranes. 1859, 12, p. 2483-2494Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Food preference and performance of the larvae of a specialist herbivore: variation among and within host-plant populations
Leimu, R., Riipi, M. & Stærk, Dan, 2005, In: Acta Oecologica. 28, p. 325-330Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Forbedret test af nye lægemidler mod malaria
Christensen, J., Stærk, Dan, Ziegler, H. L., Sairafianpour, M. & Jaroszewski, J. W., 2001, In: Lægemiddelforskning. p. 8-9Research output: Contribution to journal › Journal article › Communication
- Published
Fremtidens bæredygtige medicin fra naturen: Nye teknologier hjælper med at finde nålen i høstakken
Stærk, Dan, 2022, In: Pharma. 2022, 2, p. 20-22Research output: Contribution to journal › Contribution to newspaper - Newspaper article › Communication
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Fremtidens funktionelle fødevarer - et vigtigt middel i kampen mod livsstilssygdomme
Stærk, Dan, 2012, Profil/Fødevarer & Sundhed. København: Københavns Universitet, Kommunikation, p. 18-19 2 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Communication
- Published
Fungal plasma membrane H+-ATPase inhibitory activity of o-hydroxybenzylated flavanones and chalcones from Uvaria chamae P. Beauv
Kongstad, Kenneth Thermann, Wubshet, S. G., Kjellerup, L., winther, A. L. & Stærk, Dan, 20 Jun 2015, In: Fitoterapia. 105, p. 102-106 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Furolabdane diterpenoids from Pseudodictamnus aucheri (Boiss.) Salmaki & Siadati (Lamiaceae) as chemophenetic markers
Sadani, S., Sarrafi, Y. & Stærk, Dan, 2021, In: Biochemical Systematics and Ecology. 98, 4 p., 104304.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
HPLC-HRMS-SPE-NMR combined with high resolution in vitro screening for natural fungicides
Kongstad, Kenneth Thermann, Wubshet, S. G., Kjellerup, L., Winther, A. & Stærk, Dan, Dec 2016, In: Planta Medica. 82, S 01Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
HPLC-HRMS-SPE-NMR for accelerated identification of compounds in complex plant extracts: New coumarine derivatives from Coleonema album (Thunb.) Bartl. & Wendl
de Cássia Lemos Lima, R., Gramsbergen, S. M., Van Staden, J., Jäger, A. K., Kongstad, Kenneth Thermann & Stærk, Dan, Dec 2016, In: Planta Medica. 82, S 01Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
HPLC-NMR Techniques for Plant Extract Analysis
Stærk, Dan, Lambert, M. & Jaroszewski, J. W., 20 Mar 2008, Medicinal Plant Biotechnology: From Basic Research to Industrial Applications. Wiley-VCH, p. 29-48 20 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
HPLC-NMR techniques for plant extract analysis
Stærk, Dan, Lambert, M. & Jaroszewski, J. W., 2006, Medicinal Plant Biotechnology. From Basic Research to Applications. Kayser, O. & Quax, W. J. (eds.). Weinheim: Wiley-VCH, p. 29-48Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
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HPLC-SPE-NMR hyphenation in natural products research: optimization of analysis of Croton membranaceus extract
Lambert, M., Stærk, Dan, Hansen, S. H. & Jaroszewski, J. W., 2005, In: Magnetic Resonance in Chemistry. 43, p. 771-775Research output: Contribution to journal › Journal article › Research › peer-review
- Published
HPLC-SPE-NMR identification of a novel metabolite containing the benzo[c]oxepin skeleton from the endophytic fungus Pestalotiopsis virgatula culture
Kesting, J. R., Stærk, Dan, Tejesvi, M. V., Kini, K. R., Prakash, H. S. & Jaroszewski, J. W., 2009, In: Planta Medica. 75, 10, p. 1104-1106 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hemolymph metabolites and osmolality are tightly linked to cold tolerance of Drosophila species: a comparative study
Olsson, T., MacMillan, H. A., Nyberg, N., Stærk, Dan, Malmendal, A. & Overgaard, J., 15 Aug 2016, In: The Journal of Experimental Biology. 219, 16, p. 2504-2513 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Heterologous production of the widely used natural food colorant carminic acid in Aspergillus nidulans
Frandsen, R. J. N., Khorsand-Jamal, P., Kongstad, Kenneth Thermann, Nafisi, M., Kannangara, R. M., Stærk, Dan, Okkels, F. T., Binderup, K., Madsen, B., Møller, Birger Lindberg, Thrane, U. & Mortensen, U. H., 2018, In: Scientific Reports. 8, p. 1-10 10 p., 12853.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High resolution antioxidant assay guided HPLC-HRMS-SPE-NMR analysis of Penicillium namyslowskii extract
Wubshet, S. G., Nyberg, N. & Stærk, Dan, 2012.Research output: Contribution to conference › Poster › Research
- Published
High resolution techniques: General discussion
Adair, E., Afonso, C., Bell, N. G. A., Davies, A. N., Delsuc, M. A., Godfrey, R., Goodacre, R., Hawkes, J. A., Hertkorn, N., Jones, D., Lameiras, P., Le Guennec, A., Lubben, A., Nilsson, M., Paša-Tolić, L., Richards, J., Rodgers, R. P., Rüger, C. P., Schmitt-Kopplin, P., Schoenmakers, P. J. & 8 others, , 1 Jan 2019, In: Faraday Discussions. 218, p. 247-267 21 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
High-dose naloxone, an experimental tool uncovering latent sensitisation: pharmacokinetics in humans.
Papathanasiou, T., Springborg, A., Kongstad, Kenneth Thermann, Stærk, Dan, Møller, Kirsten, Taylor, B. K., Lund, Trine Meldgaard & Werner, M. U., 2019, In: British Journal of Anaesthesia. 123, 2, p. e204-e214Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High-resolution Assays Combined with HPLC-HRMS-SPE-ttNMR for Identification of Antidiabetic Compounds in root of Scutellaria Baicalensis
Tahtah, Y., Jønsson, L. H., Nyberg, N., Jäger, A. & Stærk, Dan, 2014.Research output: Contribution to conference › Poster › Research
- Published
High-resolution PTP1B inhibition profiling combined with HPLC-HRMS-SPE-NMR for identification of PTP1B inhibitors from Miconia albicans
Lima, R. D. C. L., Kongstad, Kenneth Thermann, Kato, L., José das Silva, M., Franzyk, Henrik & Stærk, Dan, 2018, In: Molecules. 23, 7, 13 p., 1755.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High-resolution PTP1B inhibition profiling combined with high-performance liquid chromatography - high-resolution mass spectrometry - solid-phase extraction - nuclear magnetic resonance spectroscopy: Proof-of-concept and antidiabetic constituents in crude extract of Eremophila lucida
Tahtah, Y., Wubshet, S. G., Kongstad, Kenneth Thermann, Heskes, A. M., Pateraki, Irini, Møller, Birger Lindberg, Jäger, A. & Stærk, Dan, 2016, In: Fitoterapia. 110, p. 52-58 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High-resolution assays combined with HPLC for identification of antidiabetic constituents in Vietnamese plants
Trinh, T. D. B., Stærk, Dan & Jäger, A. K., 26 Aug 2015.Research output: Contribution to conference › Poster › Research
- Published
High-resolution bacterial growth inhibition profiling combined with HPLC-HRMS-SPE-NMR for identification of antibacterial constituents in Chinese plants used to treat snakebites
Liu, Y., Nielsen, M., Stærk, Dan & Jäger, A., 2014, In: Journal of Ethnopharmacology. 155, 2, p. 1276-1283 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 1299056
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Identification of α-glucosidase inhibitors in apple peel - a chemometric approach
Research output: Contribution to conference › Poster › Research
Published -
4055
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Itoside A and 4-hydroxytremulacin from Dovyalis caffra and Dovyalis zeyheri
Research output: Contribution to journal › Journal article › Research › peer-review
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3008
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Identification of reaction products between drug substances and excipients by HPLC-SPE-NMR: Ester and amide formation between citric acid and 5-aminosalicylic acid
Research output: Contribution to journal › Journal article › Research › peer-review
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