Bente Frølund
Professor
Medicinal Chemistry
Jagtvej 162
2100 København Ø
- Published
New synthesis and tritium labeling of a selective ligand for studying high-affinity γ-hydroxybutyrate (GHB) binding sites
Vogensen, S. B., Marek, A., Bay, T., Wellendorph, Petrine, Kehler, J., Bundgaard, C., Frølund, Bente, Pedersen, M. H. F. & Clausen, Rasmus Prætorius, 2013, In: Journal of Medicinal Chemistry. 56, 20, p. 8201–8205Research output: Contribution to journal › Journal article › Research › peer-review
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Målrettet fisketur i hjernen giver ny viden om Fantasy’s virkningssted
Villumsen, I. S., Vogensen, S. B., Frølund, Bente, Clausen, Rasmus Prætorius & Wellendorph, Petrine, 2011, In: Lægemiddelforskning. 2011, p. 26-28Research output: Contribution to journal › Journal article › Communication
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Målrettet fisketur i hjernen giver ny viden om Fantasys virkningssted
Villumsen, I. S., Vogensen, S. B., Frølund, Bente, Clausen, Rasmus Prætorius & Wellendorph, Petrine, Dec 2011, In: Lægemiddelforskning. 2011, p. 26-28Research output: Contribution to journal › Journal article › Communication
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Differences in kinetics of structurally related competitive GABAA receptor antagonists
Vestergaard, H. T., Cannillo, C., Frølund, Bente & Kristiansen, Uffe, 2007, In: Neuropharmacology. 52, 3, p. 873-882Research output: Contribution to journal › Journal article › Research › peer-review
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Imidazole-4-acetic acid, a new lead structure for interaction with the taurine transporter in outer blood-retinal barrier cells
Valembois, S. A. N., Krall, J., Frølund, Bente & Steffansen, B., 30 May 2017, In: European Journal of Pharmaceutical Sciences. 103, p. 77-84 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Synthesis, pharmacology and biostructural characterization of novel a4ß2 nicotinic acetylcholine receptor agonists
Ussing, C. A., Hansen, C. P., Petersen, J. G., Jensen, Anders A., Rohde, L. A. H., Ahring, P. K., Nielsen, E. Ø., Kastrup, Jette Sandholm Jensen, Gajhede, Michael, Frølund, Bente & Balle, T., 2013, In: Journal of Medicinal Chemistry. 56, 3, p. 940-951Research output: Contribution to journal › Journal article › Research › peer-review
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Exploring the NCS-382 Scaffold for CaMKII alpha Modulation: Synthesis, Biochemical Pharmacology, and Biophysical Characterization of Ph-HTBA as a Novel High-Affinity Brain-Penetrant Stabilizer of the CaMKII alpha Hub Domain
Tian, Yongsong, Shehata, M. A., Gauger, Stine Juul, Veronesi, C., Hamborg, L., Thiesen, L., Bruus-Jensen, J., Royssen, J. S., Leurs, U., Larsen, A. S. G., Krall, J., Solbak, Sara Marie Øie, Wellendorph, Petrine & Frølund, Bente, 2022, In: Journal of Medicinal Chemistry. 65, 22, p. 15066–15084Research output: Contribution to journal › Journal article › Research › peer-review
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Discovery and Optimization of 5-Hydroxy-Diclofenac toward a New Class of Ligands with Nanomolar Affinity for the CaMKIIα Hub Domain
Tian, Yongsong, Shehata, M. A., Gauger, Stine Juul, Ng, C. K. L., Solbak, Sara Marie Øie, Thiesen, L., Bruus-Jensen, J., Krall, J., Bundgaard, C., Gibson, K. M., Wellendorph, Petrine & Frølund, Bente, 2022, In: Journal of Medicinal Chemistry. 65, 9, p. 6656-6676Research output: Contribution to journal › Journal article › Research › peer-review
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Lack of evidence for synaptic high-affinity γ-hydroxybutyric acid (GHB) transport in rat brain synaptosomes and 11 Na+ -dependent SLC neurotransmitter transporters
Thiesen, L., Frølund, Bente & Wellendorph, Petrine, Apr 2019, In: Journal of Neurochemistry. 149, 2, p. 195-210 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
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In vitro and in vivo evidence for active brain uptake of the GHB analogue HOCPCA by the monocarboxylate transporter subtype 1
Thiesen, L., Kehler, J., Clausen, Rasmus Prætorius, Frølund, Bente, Bundgaard, C. & Wellendorph, Petrine, 2015, In: Journal of Pharmacology and Experimental Therapeutics. 354, 2, p. 166-174 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 1302625
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5-(Piperidine-4-yl)-3-hydroxypyrazole: a novel scaffold forprobing the orthosteric GABAA receptor binding site
Research output: Contribution to conference › Poster › Research
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269
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Functional characterization of GABAA receptor-mediated modulation of cortical neuron network activity in microelectrode array recordings
Research output: Contribution to journal › Journal article › Research › peer-review
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181
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Discovery of a new class of orthosteric antagonists with nanomolar potency at extrasynaptic GABAA receptors
Research output: Contribution to journal › Journal article › Research › peer-review
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