Christian Adam Olsen
Professor
Biopharmaceuticals
Jagtvej 162
2100 København Ø
- Published
Design, Synthesis, Biological Evaluation, and Structural Characterization of Potent Histone Deacetylase Inhibitors Based on Cyclic alpha/beta-Tetrapeptide Architectures
Montero, A., Beierle, J. M., Olsen, Christian Adam & Ghadiri, M. R., 4 Mar 2009, In: Journal of the American Chemical Society. 131, 8, p. 3033-3041Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lipids Reprogram Metabolism to Become a Major Carbon Source for Histone Acetylation
McDonnell, E., Crown, S. B., Fox, D. B., Kitir, B., Ilkayeva, O. R., Olsen, Christian Adam, Grimsrud, P. A. & Hirschey, M. D., 1 Nov 2016, In: Cell Reports. 17, 6, p. 1463-1472 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Arylfluorosulfate-Based Electrophiles for Covalent Protein Labeling: A New Addition to the Arsenal
Martín-Gago, P. & Olsen, Christian Adam, 21 Jan 2019, In: Angewandte Chemie - International Edition. 58, 4, p. 957-966 10 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Innovative Strategies for Selective Inhibition of Histone Deacetylases
Maolanon, A. R., Madsen, A. S. & Olsen, Christian Adam, 21 Jul 2016, In: Cell Chemical Biology. 23, 7, p. 759-768 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Methyl effect in azumamides provides insight into histone deacetylase inhibition by macrocycles
Maolanon, A. R., Villadsen, J. S., Christensen, Niels Johan, Hoeck, C., Friis, T., Harris, P., Gotfredsen, C. H., Fristrup, P. & Olsen, Christian Adam, 2014, In: Journal of Medicinal Chemistry. 57, 22, p. 9644-9657 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Natural and Synthetic Macrocyclic Inhibitors of the Histone Deacetylase Enzymes
Maolanon, A., Kristensen, H., Leman, L., Ghadiri, R. & Olsen, Christian Adam, 2017, In: ChemBioChem. 18, 1, p. 5-49 45 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Substrates for Efficient Fluorometric Screening Employing the NAD-Dependent Sirtuin 5 Lysine Deacylase (KDAC) Enzyme
Madsen, A. S. & Olsen, Christian Adam, 14 Jun 2012, In: Journal of Medicinal Chemistry. 55, 11, p. 5582-5590Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Effect of Various Zinc Binding Groups on Inhibition of Histone Deacetylases 1-11
Madsen, A. S., Kristensen, H. M. E., Lanz, A. G. & Olsen, Christian Adam, Mar 2014, In: ChemMedChem. 9, 3, p. 614-626 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A potent trifluoromethyl ketone histone deacetylase inhibitor exhibits class-dependent mechanism of action
Madsen, A. S. & Olsen, Christian Adam, 2016, In: MedChemComm. 7, p. 464-470 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Investigating the Sensitivity of NAD(+)-dependent Sirtuin Deacylation Activities to NADH
Madsen, A. S., Andersen, C., Daoud, M., Anderson, K. A., Laursen, J. S., Chakladar, S., Huynh, F. K., Colaco, A. R., Backos, D. S., Fristrup, P., Hirschey, M. D. & Olsen, Christian Adam, 25 Mar 2016, In: Journal of Biological Chemistry. 291, 13, p. 7128-7141 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 101364066
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Synthesis and antiangiogenic activity of N-alkylated levamisole derivatives
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391
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Cross-Talk between Staphylococcus aureus and Other Staphylococcal Species via the agr Quorum Sensing System
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360
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The agr inhibitors solonamide B and analogues alter immune responses to Staphylococccus aureus but do not exhibit adverse effects on immune cell functions
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