Jesper M. Mathiesen

Jesper M. Mathiesen

Associate Professor


  1. Published

    mGluR5: Exploration of Orthosteric and Allosteric Ligand Binding Pockets and Their Applications to Drug Discovery

    Mølck, C., Harpsøe, Kasper, Gloriam, David E., Mathiesen, Jesper M., Nielsen, S. M. & Bräuner, Hans, Oct 2014, In: Neurochemical Research. 39, 10, p. 1862-1875 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    cAMP biosensors applied in molecular pharmacological studies of G protein-coupled receptors

    Mathiesen, Jesper M., Vedel, L. & Bräuner, Hans, 2013, In: Methods in Enzymology. 522, p. 191-207 17 p.

    Research output: Contribution to journalJournal articleResearch

  3. Published

    The metabotropic glutamate receptor 4 is internalized and desensitized upon protein kinase C activation

    Mathiesen, Jesper M. & Ramirez, M. T., 1 Jun 2006, In: British Journal of Pharmacology. 148, 3, p. 279-290 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    The C-terminal tail of CRTH2 is a key molecular determinant that constrains GalphaI- and downstream-signaling cascade activation

    Schroeder, R., Merten, N., Mathiesen, Jesper M., Martini, L., Letunic, A. K., Krop, F., Blaukat, A., Fang, Y., Tran, E., Ulven, Trond, Drewke, C., Whistler, J., Pardo, L., Gomeza, J. & Kostenis, E., 2009, In: Journal of Biological Chemistry. 284, 2, p. 1324-1336 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Structures of metabotropic GABAB receptor

    Papasergi-Scott, M. M., Robertson, M. J., Seven, A. B., Panova, O., Mathiesen, Jesper M. & Skiniotis, G., 2020, In: Nature. 584, 7820, p. 310-314 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Structure-activity relationships for negative allosteric mGluR5 modulators

    Kaae, B. H., Harpsøe, Kasper, Kvist, T., Mathiesen, Jesper M., Mølck, C., Gloriam, David E., Jimenez, H. N., Uberti, M. A., Nielsen, S. M., Nielsen, Birgitte, Bräuner, Hans, Sauerberg, P., Clausen, Rasmus Prætorius & Madsen, Ulf, 2012, In: ChemMedChem. 7, 3, p. 440-451

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Structural insights into the activation of metabotropic glutamate receptors

    Koehl, A., Hu, H., Feng, D., Sun, B., Zhang, Y., Robertson, M. J., Chu, M., Kobilka, T. S., Laeremans, T., Steyaert, J., Tarrasch, J., Dutta, S., Fonseca, R., Weis, W. I., Mathiesen, Jesper M., Skiniotis, G. & Kobilka, B. K., 7 Feb 2019, In: Nature. 566, 7742, p. 79-84

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Structural insights into differences in G protein activation by family A and family B GPCRs

    Hilger, D., Kumar, K. K., Hu, H., Pedersen, M. F., O'Brien, E. S., Giehm, L., Jennings, C., Eskici, G., Inoue, A., Lerch, M., Mathiesen, Jesper M., Skiniotis, G. & Kobilka, B. K., 2020, In: Science. 369, 6503

    Research output: Contribution to journalComment/debateResearchpeer-review

  9. Published

    Structural Insights into the Process of GPCR-G Protein Complex Formation

    Liu, X., Xu, X., Hilger, D., Aschauer, P., Tiemann, J. K. S., Du, Y., Liu, H., Hirata, K., Sun, X., Guixa-Gonzalez, R., Mathiesen, Jesper M., Hildebrand, P. W. & Kobilka, B. K., 16 May 2019, In: Cell. 177, 5, p. P1243-1251

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Real-time trafficking and signaling of the glucagon-like peptide-1 receptor

    Roed, S. N., Wismann, P., Underwood, C. R., Kulahin, N., Iversen, H., Cappelen, K. A., Schäffer, L., Lehtonen, J., Hecksher-Soerensen, J., Secher, A., Mathiesen, Jesper M., Bräuner, Hans, Whistler, J. L., Knudsen, S. M. & Waldhoer, M., Feb 2014, In: Molecular and Cellular Endocrinology. 382, 2, p. 938-949 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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