Albert J. Kooistra

Albert J. Kooistra

Associate Professor


  1. 2014
  2. From three-dimensional GPCR structure to rational ligand discovery

    Kooistra, Albert J., Leurs, R., De Esch, I. J. P. & Graaf, C. D., 1 Jan 2014, G Protein-Coupled Receptors - Modeling and Simulation. Springer New York LLC, p. 129-157 29 p. (Advances in Experimental Medicine and Biology, Vol. 796).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  3. The Receptor Concept in 3D: From Hypothesis and Metaphor to GPCR–Ligand Structures

    Kooistra, Albert J., de Graaf, C. & Timmerman, H., 1 Jan 2014, In: Neurochemical Research. 39, 10, p. 1850-1861 12 p.

    Research output: Contribution to journalReviewResearchpeer-review

  4. KLIFS: A knowledge-based structural database to navigate kinase-ligand interaction space

    Van Linden, O. P. J., Kooistra, Albert J., Leurs, R., De Esch, I. J. P. & De Graaf, C., 23 Jan 2014, In: Journal of Medicinal Chemistry. 57, 2, p. 249-277 29 p.

    Research output: Contribution to journalReviewResearchpeer-review

  5. 2015
  6. Analyzing multitarget activity landscapes using protein-ligand interaction fingerprints: Interaction cliffs

    Méndez-Lucio, O., Kooistra, Albert J., Graaf, C. D., Bender, A. & Medina-Franco, J. L., 23 Feb 2015, In: Journal of Chemical Information and Modeling. 55, 2, p. 251-262 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. The viral G protein-coupled receptor ORF74 hijacks β-arrestins for endocytic trafficking in response to human chemokines

    De Munnik, S. M., Kooistra, Albert J., Van Offenbeek, J., Nijmeijer, S., De Graaf, C., Smit, M. J., Leurs, R. & Vischer, H. F., 20 Apr 2015, In: PLOS ONE. 10, 4, e0124486.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Combinatorial consensus scoring for ligand-based virtual fragment screening: A comparative case study for serotonin 5-HT3A, histamine H1, and Histamine H4 receptors

    Schultes, S., Kooistra, Albert J., Vischer, H. F., Nijmeijer, S., Haaksma, E. E. J., Leurs, R., De Esch, I. J. P. & De Graaf, C., 26 May 2015, In: Journal of Chemical Information and Modeling. 55, 5, p. 1030-1034 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Structure-based prediction of g-protein-coupled receptor ligand function: A β-adrenoceptor case study

    Kooistra, Albert J., Leurs, R., De Esch, I. J. P. & De Graaf, C., 26 May 2015, In: Journal of Chemical Information and Modeling. 55, 5, p. 1045-1061 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Structure-based virtual screening for fragment-like ligands of the G protein-coupled histamine H4 receptor

    Istyastono, E. P., Istyastono, E. P., Kooistra, Albert J., Vischer, H. F., Kuijer, M., Roumen, L., Nijmeijer, S., Smits, R. A., De Esch, I. J. P., Leurs, R. & De Graaf, C., 1 Jun 2015, In: MedChemComm. 6, 6, p. 1003-1017 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. 2016
  12. KLIFS: A structural kinase-ligand interaction database

    Kooistra, Albert J., Kanev, G. K., Van Linden, O. P. J., Leurs, R., De Esch, I. J. P. & De Graaf, C., 1 Jan 2016, In: Nucleic Acids Research. 44, D1, p. D365-D371

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Function-specific virtual screening for GPCR ligands using a combined scoring method

    Kooistra, Albert J., Vischer, H. F., McNaught-Flores, D., Leurs, R., De Esch, I. J. P. & De Graaf, C., 24 Jun 2016, In: Scientific Reports. 6, 28288.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 196033213