Albert J. Kooistra

Albert J. Kooistra

Associate Professor

ORCID: 0000-0001-5514-6021

Publication year:
All
1 - 25 out of 53Page size: 25
Sort by: 1st author

  1. Identification of novel α7 nicotinic receptor ligands by in silico screening against the crystal structure of a chimeric α7 receptor ligand binding domain

    Akdemir, A., Edink, E., Thompson, A. J., Lummis, S. C. R., Kooistra, Albert J., De Graaf, C. & De Esch, I. J. P., 1 Oct 2012, In: Bioorganic and Medicinal Chemistry. 20, 19, p. 5992-6002 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Structure-Based Virtual Screening for Ligands of G Protein-Coupled Receptors: What Can Molecular Docking Do for You?

    Ballante, F., Kooistra, Albert J., Kampen, S., de Graaf, C. & Carlsson, J., 2021, In: Pharmacological Reviews. 73, 4, p. 527-565

    Research output: Contribution to journal › Review › Research › peer-review

  3. Route to Prolonged Residence Time at the Histamine H1 Receptor: Growing from Desloratadine to Rupatadine

    Bosma, R., Wang, Z., Kooistra, Albert J., Bushby, N., Kuhne, S., van den Bor, J., Waring, M. J., de Graaf, C., de Esch, I. J., Vischer, H. F., Sheppard, R. J., Wijtmans, M. & Leurs, R., 25 Jul 2019, In: Journal of Medicinal Chemistry. 62, 14, p. 6630-6644 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    A community Biased Signaling Atlas

    Caroli, J., Mamyrbekov, A., Harpsøe, Kasper, Gardizi, S., Dörries, L., Ghosh, E., Hauser, Alexander Sebastian, Kooistra, Albert J. & Gloriam, David E., 2023, In: Nature Chemical Biology. 19, p. 531–535

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  5. Crystal structure-based virtual screening for fragment-like ligands of the human histamine H 1 receptor

    De Graaf, C., Kooistra, Albert J., Vischer, H. F., Katritch, V., Kuijer, M., Shiroishi, M., Iwata, S., Shimamura, T., Stevens, R. C., De Esch, I. J. P. & Leurs, R., 8 Dec 2011, In: Journal of Medicinal Chemistry. 54, 23, p. 8195-8206 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Small and colorful stones make beautiful mosaics: Fragment-based chemogenomics

    De Graaf, C., Vischer, H. F., De Kloe, G. E., Kooistra, Albert J., Nijmeijer, S., Kuijer, M., Verheij, M. H. P., England, P. J., Van Muijlwijk-Koezen, J. E., Leurs, R. & De Esch, I. J. P., 1 Apr 2013, In: Drug Discovery Today. 18, 7-8, p. 323-330 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. The viral G protein-coupled receptor ORF74 hijacks β-arrestins for endocytic trafficking in response to human chemokines

    De Munnik, S. M., Kooistra, Albert J., Van Offenbeek, J., Nijmeijer, S., De Graaf, C., Smit, M. J., Leurs, R. & Vischer, H. F., 20 Apr 2015, In: PLOS ONE. 10, 4, e0124486.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    GPCR activation mechanisms across classes and macro/microscales

    Hauser, Alexander Sebastian, Kooistra, Albert J., Munk, C., Heydenreich, F. M., Veprintsev, D. B., Bouvier, M., Babu, M. M. & Gloriam, David E., 2021, In: Nature Structural and Molecular Biology. 28, 11, p. 879-888

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Utilizing drug-target-event relationships to unveil safety patterns in pharmacovigilance

    Hauser, Alexander Sebastian, Kooistra, Albert J., Sverrisdóttir, E. & Sessa, Maurizio, 2020, In: Expert Opinion on Drug Safety. 19, p. 961-968

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Synthesis and Characterization of a Bidirectional Photoswitchable Antagonist Toolbox for Real-Time GPCR Photopharmacology

    Hauwert, N. J., Mocking, T. A. M., Da Costa Pereira, D., Kooistra, Albert J., Wijnen, L. M., Vreeker, G. C. M., Verweij, E. W. E., De Boer, A. H., Smit, M. J., De Graaf, C., Vischer, H. F., De Esch, I. J. P., Wijtmans, M. & Leurs, R., 28 Mar 2018, In: Journal of the American Chemical Society. 140, 12, p. 4232-4243 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Structure-based virtual screening for fragment-like ligands of the G protein-coupled histamine H4 receptor

    Istyastono, E. P., Istyastono, E. P., Kooistra, Albert J., Vischer, H. F., Kuijer, M., Roumen, L., Nijmeijer, S., Smits, R. A., De Esch, I. J. P., Leurs, R. & De Graaf, C., 1 Jun 2015, In: MedChemComm. 6, 6, p. 1003-1017 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Molecular determinants of ligand binding modes in the histamine H 4 receptor: Linking ligand-based three-dimensional quantitative structure-activity relationship (3D-QSAR) models to in silico guided receptor mutagenesis studies

    Istyastono, E. P., Nijmeijer, S., Lim, H. D., Van De Stolpe, A., Roumen, L., Kooistra, Albert J., Vischer, H. F., De Esch, I. J. P., Leurs, R. & De Graaf, C., 8 Dec 2011, In: Journal of Medicinal Chemistry. 54, 23, p. 8136-8147 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. PDEStrIAn: A Phosphodiesterase Structure and Ligand Interaction Annotated Database As a Tool for Structure-Based Drug Design

    Jansen, C., Kooistra, Albert J., Kanev, G. K., Leurs, R., De Esch, I. J. P. & De Graaf, C., 11 Aug 2016, In: Journal of Medicinal Chemistry. 59, 15, p. 7029-7065 37 p.

    Research output: Contribution to journal › Review › Research › peer-review

  14. Discovery of novel Trypanosoma brucei phosphodiesterase B1 inhibitors by virtual screening against the unliganded TbrPDEB1 crystal structure

    Jansen, C., Wang, H., Kooistra, Albert J., De Graaf, C., Orrling, K. M., Tenor, H., Seebeck, T., Bailey, D., De Esch, I. J. P., Ke, H. & Leurs, R., 14 Mar 2013, In: Journal of Medicinal Chemistry. 56, 5, p. 2087-2096 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Structural Chemogenomics Databases to Navigate Protein-Ligand Interaction Space

    Kanev, G. K., Kooistra, Albert J., de Esch, I. J. P. & de Graaf, C., 3 Jun 2017, The Future of Drug Discovery. Elsevier Science Inc., Vol. 1-8. p. 444-471 28 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  16. Published

    KLIFS: an overhaul after the first 5 years of supporting kinase research

    Kanev, G. K., de Graaf, C., Westerman, B. A., de Esch, I. J. P. & Kooistra, Albert J., 2021, In: Nucleic Acids Research. 49, D1, p. D562-D569

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. The Landscape of Atypical and Eukaryotic Protein Kinases

    Kanev, G. K., de Graaf, C., de Esch, I. J. P., Leurs, R., Würdinger, T., Westerman, B. A. & Kooistra, Albert J., Nov 2019, In: Trends in Pharmacological Sciences. 40, 11, p. 818-832 15 p.

    Research output: Contribution to journal › Review › Research › peer-review

  18. Published

    Predicting the target landscape of kinase inhibitors using 3D convolutional neural networks

    Kanev, G. K., Zhang, Y., Kooistra, Albert J., Bender, A., Leurs, R., Bailey, D., Würdinger, T., Graaf, C. D., de Esch, I. J. P. & Westerman, B. A., 2023, In: PLOS Computational Biology. 19, 9, 19 p., e1011301.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. A structural chemogenomics analysis of aminergic GPCRs: Lessons for histamine receptor ligand design

    Kooistra, Albert J., Kuhne, S., De Esch, I. J. P., Leurs, R. & De Graaf, C., 1 Sep 2013, In: British Journal of Pharmacology. 170, 1, p. 101-126 26 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    GPCRdb in 2021: integrating GPCR sequence, structure and function

    Kooistra, Albert J., Mordalski, S., Pándy-Szekeres, Gáspár, Esguerra, M., Mamyrbekov, A., Munk, C., Keserű, G. M. & Gloriam, David E., 2021, In: Nucleic Acids Research. 49, D1, p. D335-D343

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. From three-dimensional GPCR structure to rational ligand discovery

    Kooistra, Albert J., Leurs, R., De Esch, I. J. P. & Graaf, C. D., 1 Jan 2014, G Protein-Coupled Receptors - Modeling and Simulation. Springer New York LLC, p. 129-157 29 p. (Advances in Experimental Medicine and Biology, Vol. 796).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  22. From heptahelical bundle to hits from the haystack: Structure-based virtual screening for GPCR ligands

    Kooistra, Albert J., Roumen, L., Leurs, R., De Esch, I. J. P. & De Graaf, C., 11 Feb 2013, G Protein Coupled ReceptorsModeling, Activation, Interactions and Virtual Screening. p. 279-336 58 p. (Methods in Enzymology, Vol. 522).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  23. The Receptor Concept in 3D: From Hypothesis and Metaphor to GPCR–Ligand Structures

    Kooistra, Albert J., de Graaf, C. & Timmerman, H., 1 Jan 2014, In: Neurochemical Research. 39, 10, p. 1850-1861 12 p.

    Research output: Contribution to journal › Review › Research › peer-review

  24. Published

    An online GPCR structure analysis platform

    Kooistra, Albert J., Munk, C., Hauser, Alexander Sebastian & Gloriam, David E., 2021, In: Nature Structural and Molecular Biology. 28, 11, p. 875-878

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Function-specific virtual screening for GPCR ligands using a combined scoring method

    Kooistra, Albert J., Vischer, H. F., McNaught-Flores, D., Leurs, R., De Esch, I. J. P. & De Graaf, C., 24 Jun 2016, In: Scientific Reports. 6, 28288.

    Research output: Contribution to journal › Journal article › Research › peer-review

Previous 1 2 3 Next

ID: 196033213